Emulsion
Presented By- Saurabh Dubey
M.Pharm
Bundelkhand University
Emulsion
Biphasic system consisting of two
immiscible liquids usually water and oil.
• It consists of two phase
Internal phase -Dispersed or Discontinuous
External phase -Dispersion or Continuous
Emulsion is coarse dispersion having globule
size 0.1-100 mm
• It may be defined as biphasic liquid dosage
form in which two liquids are immiscible
with each other.
• Thermodynamically unstable, emulsifying
agents are needed
Preparation
Method
Dry Gum methods (4 Part Oil,1 Part Gum, 2 Part
Water)
Oil + Gum Triturate Add water Again
→ → →
Triturate
Wet gum method (4 Parts Oil, 1 Part Gum, 2 Part
Water)
Water + Gum Triturate Add oil Again
→ → →
Triturate
Bottle method Used for volatile or Non viscous
oils
1Part Gum + 4 Part Oil + Required Water – Add in
Dry Capped Bottle and Thoroughly shaken
Types of
Emulsion
Macro Emulsion
a) O/W
b) W/O
Multiple Emulsion
a) O/W/O
b) W/O/W
Micro Emulsion- Size range - 0.01 - 0. 1 μ
Microemulsions are clear,
thermodynamically stable isotropic liquid
mixtures of oil, water and surfactant,
frequently in combination with a
cosurfactant.
Problem of Emulsion
Identification Test of Emulsion
1. Dilution test-
Emulsion can be diluted
only with external phase.
2. Dye test- Water-
soluble solid dye tints
only o/w emulsion and
also vice versa.
3. Conductivity
test- Electric current is
conducted by o/w
emulsions because water
is the good conductor of
electricity
4. Fluorescence
test- Since oils fluoresce
under UV-light so o/w
emulsions exhibit dot
pattern, while w/o
emulsions fluoresce
throughout.
5. CoCl2 / filter paper
test- Filter paper
impregnated with CoCl2
and dried, blue color
changes to pink when
(O/W) emulsion is added.
6. Creaming
test- Direction of
creaming helps in the
identification
• O/W - upward creaming
• W/O - downward
creaming
Emulsion ppt & pdf B.Pharm , M.Pharm, Pharmacy

Emulsion ppt & pdf B.Pharm , M.Pharm, Pharmacy

  • 1.
    Emulsion Presented By- SaurabhDubey M.Pharm Bundelkhand University
  • 2.
    Emulsion Biphasic system consistingof two immiscible liquids usually water and oil. • It consists of two phase Internal phase -Dispersed or Discontinuous External phase -Dispersion or Continuous Emulsion is coarse dispersion having globule size 0.1-100 mm • It may be defined as biphasic liquid dosage form in which two liquids are immiscible with each other. • Thermodynamically unstable, emulsifying agents are needed
  • 3.
    Preparation Method Dry Gum methods(4 Part Oil,1 Part Gum, 2 Part Water) Oil + Gum Triturate Add water Again → → → Triturate Wet gum method (4 Parts Oil, 1 Part Gum, 2 Part Water) Water + Gum Triturate Add oil Again → → → Triturate Bottle method Used for volatile or Non viscous oils 1Part Gum + 4 Part Oil + Required Water – Add in Dry Capped Bottle and Thoroughly shaken
  • 4.
    Types of Emulsion Macro Emulsion a)O/W b) W/O Multiple Emulsion a) O/W/O b) W/O/W Micro Emulsion- Size range - 0.01 - 0. 1 μ Microemulsions are clear, thermodynamically stable isotropic liquid mixtures of oil, water and surfactant, frequently in combination with a cosurfactant.
  • 5.
  • 6.
    Identification Test ofEmulsion 1. Dilution test- Emulsion can be diluted only with external phase. 2. Dye test- Water- soluble solid dye tints only o/w emulsion and also vice versa. 3. Conductivity test- Electric current is conducted by o/w emulsions because water is the good conductor of electricity 4. Fluorescence test- Since oils fluoresce under UV-light so o/w emulsions exhibit dot pattern, while w/o emulsions fluoresce throughout. 5. CoCl2 / filter paper test- Filter paper impregnated with CoCl2 and dried, blue color changes to pink when (O/W) emulsion is added. 6. Creaming test- Direction of creaming helps in the identification • O/W - upward creaming • W/O - downward creaming