The document outlines the role and responsibilities of a Drug and Therapeutics Committee (DTC) within a healthcare organization. The DTC conducts medication evaluations and analyses to select drugs that offer the best outcomes while minimizing risks and costs. It is responsible for medication safety monitoring, error prevention, and developing clinical guidelines. Within the National Institute of Urology Nepal, the DTC considers cost-effectiveness, safety, and patient compliance when comparing drug alternatives, and uses an evidence-based process to evaluate medications for formulary inclusion.