This document defines drugs as chemical substances that have biological effects on humans or animals. It discusses the history of drug use from ancient times to the present. Drugs are categorized as over-the-counter, behind-the-counter, or prescription only, and types include stimulants, depressants, opiates, and hallucinogens. Drugs can be administered in various ways and polydrug use carries risks. The term "drug abuse" refers to frequent use that causes harm. Commonly abused drugs are discussed like tobacco, with acute and health risks outlined.