This document provides an overview of hospital and clinical pharmacy. It discusses the definition and functions of hospital pharmacy, drug distribution systems in hospitals like unit dose and floor ward stock systems. It also covers sterile and non-sterile manufacturing, procurement, and testing. Additional topics include the pharmacy therapeutic committee, hospital formularies, drug information services, and applying computers to pharmacy work. The document then discusses clinical pharmacy practice, patient counseling, common medical terminology, and disease states. It concludes with sections on drug interactions, adverse drug reactions, clinical toxicology, drug dependence, and bioavailability.

1. HOSPITAL AND CLINICAL
PHARMACY
By
Dr.Sowmya Spoorthi .M
Assistant Professor
KLE COLLEGE OF PHARMACY

2. Part-I: Hospital Pharmacy
Hospital
• Definition,
• Function,
classifications based on various criteria,
• organization,
• Management
• health delivery system in India.

3. Hospital Pharmacy
• Definition
• Functions
• objectives of Hospital pharmaceutical services.
• Location,
• Layout,
• Flow chart of materials and men.
• Personnel and facilities requirements including equipment's based on
individual and basic needs.
• Requirements and abilities required for Hospital pharmacists

4. Drug Distribution system in Hospitals
• Out-patient service
• In-patient services
Types of services detailed discussion of :-
• unit Dose system
• Floor ward stock system
• satellite pharmacy services
• central sterile services
• Bed side pharmacy.

5. Manufacturing
• Economical considerations
• estimation of demand.

6. Sterile manufacture-
• Large and small volume parenterals,
• facilities,
• requirements,
• layout production planning
• man-power requirements.

7. Non-sterile manufacture
• Liquid orals
• Externals
• Bulk concentrates
• Procurement of stores and testing of raw materials

8. Nomenclature and uses of surgical instruments
and Hospital Equipments and health accessories.

9. P.T.C.(pharmacy Therapeutic Committee)
• P.T.C.(pharmacy Therapeutic Committee)

10. Hospital Formulary system and their
organization, functioning, composition

11. Drug Information service and Drug Information
Bulletin

12. Surgical dressing
• cotton,
• gauze,
• bandages
• adhesive tapes including their pharmacopoeial tests for quality. Other
hospital supply eg. I.V.sets, B.G. sets, Ryals tubes, Catheters, Syringes
etc

13. • Application of computers in maintenance of records, inventory
control, medication monitoring, drug information and data storage
and retrieval in hospital retail pharmacy establishment.

14. Clinical Pharmacy:
• Introduction to Clinical pharmacy practice- Definition, scope.

15. Modern dispensing aspects- Pharmacists and
patient counseling and advice for the use of
common drugs, medication history.

16. Common daily terminology used in the
practice of Medicine.

17. Disease, manifestation and patho-physiology including salient symptoms to
understand the disease like
• Tuberculosis,
• Hepatitis,
• Rheumatoid Arthritis,
• Cardio-vascular diseases,
• Epilepsy,
• Diabetes,
• Peptic Ulcer,
• Hypertension

18. • Physiological parameters with their significance.

19. Drug Interactions
• Definition of Drug Interactions
• Mechanism of Drug Interaction.
• Drug-drug interaction with reference to analgesics, diuretics,
cardiovascular drugs, Gastro-intestinal agents. Vitamins and
Hypoglycaemic agents. Drug-food interaction.

20. Adverse Drug Reaction
• Definition
• Significance.
• Drug-Induced diseases
• Teratogenicity.

21. Drugs in Clinical Toxicity
• Introduction, general treatment of poisoning, systemic antidotes,
Treatment of insecticide poisoning, heavy metal poison, Narcotic
drugs, Barbiturate, Organo-phosphorus poisons.

22. DRUG DEPENDENCE
• COMMONLY ABUSED DRUGS ,THEIR COMPLICATIONS AND
TREATMENT
• DRUG ABUSE
• DRUG ADDICTION
• DRUG HABITUATION

23. BIO-AVAILABILITY
What is mean by Bio-availability of drugs ?
What are the factors affecting Bio-availability of Drugs ?