Drift cars
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Drifting cars has become a popular hobby among young people, with competitions held to support skill development, though it carries many dangers such as fires, crashes or death. Abdo Feghali is a famous drifter in the Middle East who has won numerous tournaments.
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2018 07-cooper surgical-santiago munne_02072018
This document discusses next steps in preimplantation genetic testing (PGT). It compares different biopsy stages such as polar body, cleavage-stage embryo, and blastocyst biopsies. Blastocyst biopsy has advantages of being non-invasive, having high concordance with trophectoderm biopsy, and reducing impact of embryo biopsy. The document also discusses whole genome amplification methods like array comparative genomic hybridization and next generation sequencing that are used for PGT and their advantages and limitations. Finally, it reviews studies on the possibility of non-invasive PGT using spent culture media and highlights variables like culture conditions, amplification methods, and PGT platforms that impact the results of non-invasive testing.
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This document discusses next steps in preimplantation genetic testing (PGT). It compares different biopsy stages such as polar body, cleavage-stage embryo, and blastocyst biopsies. Blastocyst biopsy has advantages of being non-invasive, having high concordance with trophectoderm biopsy, and reducing impact of embryo biopsy. The document also discusses whole genome amplification methods like array comparative genomic hybridization and next generation sequencing that are used for PGT and their advantages and limitations. Finally, it reviews studies on the possibility of non-invasive PGT using spent culture media and highlights variables like culture conditions, amplification methods, and PGT platforms that impact the results of non-invasive testing.
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(Fiore et al., 2017).
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The presentation discusses the evolution of ovarian stimulation for assisted reproductive technology (ART). It begins with a historical perspective of gonadotropin development from urinary sources to recombinant products. It then examines primary factors affecting IVF success like age, ovarian reserve markers, and cause of infertility. The presentation concludes by exploring more individualized clinical strategies like tailoring gonadotropin doses, flexible GnRH antagonist protocols, and LH supplementation to improve IVF outcomes.
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Female infertility is the inability of a female to conceive a baby naturally. If a woman keeps having miscarriages, it is also called female infertility.
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Sperm DNA fragmentation refers to the breaking of DNA strands into pieces and can be a cause of male infertility. Approximately 25% of infertile men have higher levels of sperm DNA fragmentation. Traditional semen analysis provides limited information and does not differentiate between fertile and infertile sperm. A sperm DNA fragmentation test provides a DNA Fragmentation Index that can help predict fertility potential and avoid failed fertility treatment cycles. The test is fast, cost-effective, and does not require complex equipment. It can benefit couples facing unexplained infertility or unsuccessful fertility treatments like IUI or IVF by identifying DNA damage as a potential cause.
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3) Both phenotypes can experience insulin resistance, so lifestyle changes and insulin sensitizers may benefit both groups.
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This document discusses sperm DNA fragmentation, which refers to breaks in sperm DNA. It notes that a high level of fragmentation can compromise the possibility of a successful pregnancy. While fragmentation does not seem to affect early embryo development, it can impact later stages. Fragmentation is associated with lower success rates for treatments like IUI, IVF, and ICSI. The document outlines various tests for measuring fragmentation and notes treatment options depend on the specific cause and severity of the fragmentation. Lifestyle changes may help in some cases by reducing oxidative stress, while varicocele repair or using testicular sperm extraction with ICSI may also improve outcomes.
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Learning Objectibves :
1.To define and describe the mechanism of ovulation
2.To review the different phases of the menstrual cycle and its physiology
" Ovulation (ovum release) occurs when estradiol levels usually peak as the ovulatory phase begins. Progesterone levels also begin to increase. Stored LH is released in massive amounts (LH surge), usually over 36 to 48 hours, with a smaller increase in FSH.
Insight into AZF region of y chromosome and male infertility
1) The study analyzed 120 patients with azoospermia or severe oligospermia to evaluate the relationship between AZF microdeletions and male infertility. 2) 64% of microdeletions were located in the AZFc locus, while 20% were AZFb+c deletions and 13% were AZFb deletions. 3) AZFb deletions cause spermatogenic arrest, while AZFc deletions result in a variable phenotype ranging from hypospermatogenesis to Sertoli cell-only syndrome. Reproductive hormone levels alone cannot determine AZF microdeletions.
Cipromega training
Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic that is highly effective against both gram-positive and gram-negative bacteria. It was the first quinolone developed that could be administered orally to treat serious infections. A new extended release formulation, CiproMega, was developed to provide the benefits of once daily dosing for improved patient compliance compared to the previous twice daily dosing. Clinical trials demonstrated CiproMega was as effective as, and in some cases more effective than, the previous twice daily dosing regimen with fewer side effects.
Calcium and Vitamin D Supplementation in Pregnancy
lectured delivered by Dr Sujoy Dasgupta in the CME on "High Risk Pregnancy" organized by the BOGS (Bengal Obettric snd Gynaecological Society) and Wanburry Pharma
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This document provides information about Prof. Narendra Malhotra, including his professional qualifications and positions held. It lists that he is a practicing obstetrician gynecologist in Agra with special interests in high risk obstetrics, ultrasound, laparoscopy, infertility and genetics. It also provides information about Malhotra Nursing & Maternity Home Pvt. Ltd. and Global Rainbow Health Care in Agra.
Optimum Vitamin Nutrition (OVN) for Swine - Gilbert M. Weber
Recent research on vitamin requirement of modern swine breeds under current husbandry conditions is limited; tabular recommendations may underestimate the actual needs of growing pigs and breeding sows.
Clinical / subclinical vitamin deficiency can still occur within industrial swine production:
optimum vitamin supplementation prevents from deficiency and
exploits the genetic performance potential of swine.
Superior dietary supplementation levels of certain vitamins do provide additional value, such as improved stress and disease resistance, adequate welfare or better product quality.
Adjuvants in por (1)
Role of adjuvants in poor ovarian responders , undergoing infertility treatment , in terms of Intra uterine inseminations ( IUI ) to In Vitro Fertilization ( IVF )
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Drug induced bone marrow suppression can occur through direct toxicity or idiosyncratic reactions. The timing and severity of myelosuppression from chemotherapy depends on the drug characteristics, patient factors, and blood cell life cycles. Common mechanisms include damaging proliferating progenitor cells or stem cells in the bone marrow. Diagnosis involves monitoring blood counts, and treatment focuses on managing complications and supporting blood cell production.
Update in vzv in preg.
This document discusses varicella zoster virus (VZV) infection in pregnancy. It notes that VZV causes chickenpox and shingles. Infection in pregnancy carries risks for both mother and fetus. For the fetus, infection before 20 weeks can cause congenital varicella syndrome, while infection within 5 days of delivery poses risks for neonatal varicella. The document recommends varicella vaccination and outlines protocols for managing exposure during pregnancy.
Folic acid supplementation during pregnancy
1. The document discusses folic acid supplementation recommendations during pregnancy. It recommends that all women of reproductive age take a folic acid supplement before and during early pregnancy to help prevent neural tube defects and other congenital anomalies.
2. Women are classified as low, moderate, or high risk depending on their personal and family health histories. The recommendations include taking 0.4 mg, 1.0 mg, or 4.0 mg of folic acid daily based on risk level, beginning several months before conception through the first trimester and continuing through pregnancy.
3. Folic acid supplementation has been shown to reduce the risk of neural tube defects by up to half, as well as certain other birth defects, anemia
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This document discusses intracytoplasmic morphologically selected sperm injection (IMSI), a technique that uses higher magnification than conventional ICSI to select sperm for fertilization. It provides background on sperm morphology and vacuoles, and their relationship to fertility outcomes. Studies comparing IMSI to ICSI are summarized, finding improved outcomes with IMSI, especially in cases of poor semen quality or previous ICSI failure. Guidelines for when IMSI may be beneficial over conventional ICSI are presented.
Balancing Fat Nutrition to Optimise Transition Cow Performance .pptx
Balancing Fat Nutrition to Optimise Transition Cow Performance
A cow’s transition period is a key time since most of the metabolic and infectious diseases occur then.
Higher demand of energy and nutrients for the synthesis of colostrum and milk coupled with decreased feed intake force the transition cows to undergo negative energy balance (NEB) and micronutrient deficiencies. When metabolism does not meet production demands, incidence of clinical or subclinical metabolic disorders increases. Because innate and acquired immunity are suboptimal during this period, animals are more prone to infection
Proper supplementation at this moment may prevent future diseases and production losses.
In early lactation, the challenge for the cow to shift gear to accelerate copious milk production against loss of appetite results in nutrient deficiencies and subsequent negative energy balance leading to mobilisation of body reserves and compromised immunity
(Fiore et al., 2017).
Endocrine, adipose tissue, liver, digestive system and mammary gland are key components of the adaptations that dairy cows experience to achieve the necessary balance to adjust to the onset of sustained increasing milk production.
If unchecked metabolic stress in the affected cows can burden dairy producers with increased poor cow health, infertility, culling rates, inefficient nutrient utilisation and economic loss
In early lactation, the challenge for the cow to shift gear to accelerate copious milk production against loss of appetite results in nutrient deficiencies and subsequent negative energy balance leading to mobilisation of body reserves and compromised immunity
(Fiore et al., 2017).
Endocrine, adipose tissue, liver, digestive system and mammary gland are key components of the adaptations that dairy cows experience to achieve the necessary balance to adjust to the onset of sustained increasing milk production.
If unchecked metabolic stress in the affected cows can burden dairy producers with increased poor cow health, infertility, culling rates, inefficient nutrient utilisation and economic loss
In early lactation, the challenge for the cow to shift gear to accelerate copious milk production against loss of appetite results in nutrient deficiencies and subsequent negative energy balance leading to mobilisation of body reserves and compromised immunity
(Fiore et al., 2017).
Endocrine, adipose tissue, liver, digestive system and mammary gland are key components of the adaptations that dairy cows experience to achieve the necessary balance to adjust to the onset of sustained increasing milk production.
If unchecked metabolic stress in the affected cows can burden dairy producers with in
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The document discusses the process of machine design, which involves recognizing needs, specifying product requirements, selecting mechanisms and materials, developing a general configuration layout, designing individual elements, testing and modifying prototypes, and creating detailed drawings for production. Some key steps include considering various design options, balancing costs and performance, and using flexible approaches to solve problems that arise during the design process.
Types of gears
Gears are used to transmit motion between rotating shafts and can change the speed and torque characteristics. The document discusses various types of gears including spur gears, helical gears, bevel gears, worm gears, and rack and pinion gears. It also covers planetary or epicyclic gears which are used in automatic transmissions to achieve large speed reductions in a compact space. Standard specifications for parameters like pressure angle, addendum, dedendum, and circular pitch are provided for designing gear teeth.
Screw jack
The document discusses screw jacks, which are mechanical devices that use a screw mechanism to convert rotational motion into linear motion to raise or lower loads. Screw jacks operate by turning a lead screw, and can be manually operated or powered. Common types include scissor jacks and bottle jacks. The document outlines the components, materials, manufacturing processes, and assembly of a typical screw jack, noting that frames are often made of cast iron while screws use hardened steel or bronze for nuts. Screw jacks provide mechanical advantage through their screw mechanisms to allow lifting of heavy loads with minimal effort.
Brakes
The document discusses different types of braking systems used in vehicles. It describes parking brakes, service brakes, drum brakes, disc brakes, hydraulic braking systems, and anti-lock braking systems (ABS). The key components of braking systems like the master cylinder, calipers, rotors, and pads are explained. Common brake system issues and how to diagnose them are also covered.
Hydraulic turbines
contains pelton turbine , kaplan turbine , and francis turbine with their working. contains GIF and videos of working
Gearbox
The document discusses the components and operation of a gearbox. It defines a gearbox as a collection of mechanical components that deliver power from an engine through a series of gear ratios. It then describes the main components of a manual gearbox and why they are still used in sports cars due to driver control. The document outlines how different gear ratios are used to obtain varying speeds and torque levels. Finally, it details the purpose and components of a synchronized gearbox and how synchronization works in three phases to smoothly engage gears.
HYDRAULIC BRAKING SYSTEMS
Hydraulic braking systems use pressurized brake fluid to transmit force through the hydraulic circuit and generate braking force. The fluid pressure is created by the brake pedal acting on the master cylinder and distributed through the lines to the wheel cylinders or calipers, where pistons increase the force and create braking force to slow the vehicle. Drum brakes use expanding brake shoes to create friction on the inner surface of the drum, while disc brakes use calipers and brake pads to squeeze the rotor. Hydraulic systems provide balanced braking force to all wheels through proportioning valves.
Hydraulic brakes
The document discusses hydraulic brakes. It begins with an introduction explaining that hydraulic brakes use brake fluid to transfer pressure from the controlling unit like the brake pedal to the actual brake mechanism near the wheels. It then covers the classification, principles, construction, operation, and advantages/disadvantages of hydraulic brake systems. The construction section describes components like the master cylinder, wheel cylinder, brake shoes, brake drum, brake fluid, and brake lines/hoses.
Braking systems
This document summarizes different types of braking systems used in vehicles. It describes the basic requirements and components of braking systems. The main types discussed are drum brakes, disc brakes, and various power brakes such as hydraulic, vacuum, air, and electric brakes. It provides details on the construction and operation of these different braking methods. The purpose is to classify and explain the functioning of common braking technologies used to stop vehicle motion.
Screw Jack Design
The document describes the design of a screw jack that can lift up to 3 tons. It identifies the need, outlines the research conducted, and describes the components designed. The team designed a screw, nut, handle, frame, and cup. Design calculations were performed to determine specifications. Materials were selected based on withstanding torsional, bending and axial loads. The conclusion discusses using a 5/8" acme power screw and improving the design with a two start thread and longer handle to reduce required force.
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- 3. spread dramatically between young people and there is a competition based on supporting the young people and the development of skills
- 4. Has many dangers, such as the burning of the car or disintegrated or death
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- 8. Good bye