The current financial situation has forced many libraries to pay unprecedented attention to how they are organized to achieve their missions. One common thread emerging in the responses is cooperation: those needing to cut costs sharply are finding that they cannot do so incrementally but must instead transform their activities in ways that spread cost and diffuse risk among many partners. The talk will cover some of the opportunities available for transformative institutional collaboration among libraries, including collaborative, open source software development as well as the challenges facing those attempting to collaborate. It will pay particular attention to the question of how to collaborate strategically: that is, how to ensure that collaboration retains or increases a library’s ability to pursue mission, enhance agility, increase sovereignty, and improve sustainability.