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DNA Structure and
Replication
What is DNA?
 Contains genetic information for all living
things(acts as blueprint or code).
 Found in nucleus of cell.
 Shape is double helix – looks like twisted ladder
or twisted zipper.
 DNA is a polymer made of repeating subunits
called nucleotides.
 Nucleotides have three parts: a simple sugar, a
phosphate group, and a nitrogenous base.
 Backbone or sides of the ladder are the sugar
(deoxyribose).
 Rungs of the ladder or middle is the bases.
Structure
 In DNA, there are four possible nitrogenous bases:
adenine (A), guanine (G), cytosine (C), and thymine (T).
Adenine (A) Guanine (G) Thymine (T)
Cytosine (C)
Bases put into 2 categories.
Purines: A and G
Pyrimidines: T and C (both contain Y)
Base Pairing Rule
 Always Together
Adenine always pairs with Thymine
forms 2 hydrogen bonds with each other
Cytosine always pairs with Guanine
forms 3 hydrogen bonds with each other
 Amount of adenine
always equal to the
amount of thymine.
 Amount of guanine
always equal to the
amount of cytosine.
 Base pairings results
in strands that are
complementary where
sequences on one
strand determines
sequence on the
other..
Complementary base pairs
What is the complementary
stand?
 AGTACCGATACGGAATAGC
 GGTTACATAAATCGGTACC
 TACCGGAGTAGCATTACTT
 CATTACCCAATGGACGTTA
DNA Replication
 The process in which DNA makes an identical
copy of itself.
 Cell divides, DNA coils into 46 chromosomes=
23 pairs, one from mom and one from dad.
 An enzyme unzips the DNA molecule,
complementary base pairs are added to each side
of the separated strands producing two identical
DNA molecules.
Replication
of DNA
DNA
Replication
Replication
Discovery
 1949: biochemist Chargaff observed that in
DNA, A=T and G=C.
 1953: Rosalind Franklin took X-ray of DNA.
 From X-ray, Watson and Crick developed model
of DNA helix.

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DNA Structure and Replication PowerPoint

  • 2. What is DNA?  Contains genetic information for all living things(acts as blueprint or code).  Found in nucleus of cell.  Shape is double helix – looks like twisted ladder or twisted zipper.
  • 3.  DNA is a polymer made of repeating subunits called nucleotides.  Nucleotides have three parts: a simple sugar, a phosphate group, and a nitrogenous base.  Backbone or sides of the ladder are the sugar (deoxyribose).  Rungs of the ladder or middle is the bases. Structure
  • 4.  In DNA, there are four possible nitrogenous bases: adenine (A), guanine (G), cytosine (C), and thymine (T). Adenine (A) Guanine (G) Thymine (T) Cytosine (C) Bases put into 2 categories. Purines: A and G Pyrimidines: T and C (both contain Y)
  • 5. Base Pairing Rule  Always Together Adenine always pairs with Thymine forms 2 hydrogen bonds with each other Cytosine always pairs with Guanine forms 3 hydrogen bonds with each other
  • 6.  Amount of adenine always equal to the amount of thymine.  Amount of guanine always equal to the amount of cytosine.  Base pairings results in strands that are complementary where sequences on one strand determines sequence on the other.. Complementary base pairs
  • 7. What is the complementary stand?  AGTACCGATACGGAATAGC  GGTTACATAAATCGGTACC  TACCGGAGTAGCATTACTT  CATTACCCAATGGACGTTA
  • 8.
  • 9. DNA Replication  The process in which DNA makes an identical copy of itself.  Cell divides, DNA coils into 46 chromosomes= 23 pairs, one from mom and one from dad.  An enzyme unzips the DNA molecule, complementary base pairs are added to each side of the separated strands producing two identical DNA molecules.
  • 11.
  • 12. Discovery  1949: biochemist Chargaff observed that in DNA, A=T and G=C.  1953: Rosalind Franklin took X-ray of DNA.  From X-ray, Watson and Crick developed model of DNA helix.