This document discusses diseases of the external ear that can affect hearing. It begins with the anatomy and physiology of the external ear, including the pinna, external auditory canal, and tympanic membrane. It then examines various diseases of the external ear like congenital disorders (anotia, microtia, atresia), infections (furuncle), impacted earwax, foreign bodies, exostoses, and otitis externa. These conditions can lead to conductive hearing loss by obstructing sound transmission through the external ear to the middle ear and eardrum. Early diagnosis and treatment of external ear diseases are important to prevent permanent hearing impairment.
The common ENT disorders includes Ear Disorder: Ear Infections,Hearing Disorders and Deafness, Meniere's Disease. acute otitis media, tonsillopharyngitis, sore throat, adenoid disorders, epistaxis, nasal congestion and rhinorrhea, sinusitis, and ear foreign bodies and nasal foreign bodies etc.
The common ENT disorders includes Ear Disorder: Ear Infections,Hearing Disorders and Deafness, Meniere's Disease. acute otitis media, tonsillopharyngitis, sore throat, adenoid disorders, epistaxis, nasal congestion and rhinorrhea, sinusitis, and ear foreign bodies and nasal foreign bodies etc.
Understanding Hearing Loss by Jed Kwartler, MD & Marykate Vaughn, AUD - Livin...Summit Health
People of all ages experience gradual hearing loss, often due to the natural aging process, long exposure to loud noise or other medical conditions. Learn about ear anatomy, how the hearing sense works, and the most advanced surgical practices and technology for treating hearing loss.
Understanding Hearing Loss by Jed Kwartler, MD & Marykate Vaughn, AUD - Livin...Summit Health
People of all ages experience gradual hearing loss, often due to the natural aging process, long exposure to loud noise or other medical conditions. Learn about ear anatomy, how the hearing sense works, and the most advanced surgical practices and technology for treating hearing loss.
Human ear, organ of hearing and equilibrium that detects and analyzes sound by transduction (or the conversion of sound waves into electrochemical impulses) and maintains the sense of balance (equilibrium).
The outer ear consists of skin and cartilage, called the auricle, or pinna, and the ear canal. The ear drum, or tympanic membrane, is a thin membrane that separates the outer ear from the middle ear. The middle ear is an air-filled chamber containing three small bones called ossicles. The main parts of the ear are the outer ear, the eardrum (tympanic membrane), the middle ear, and the inner ear.n an adult human, 3 bones( malleus, incus, stapes) are present as ear ossicles. The outer ear is made up of cartilage and skin. There are three different parts to the outer ear; the tragus, helix and the lobule. EAR CANAL
The Ear, Anatomy, Physiology, Clinical diseases, and pathology, hearing testsHamzehKYacoub
Ear is composed of three parts: External ear, middle ear, and the Inner ear.
Hearing tests (Rinne's and Weber's tests).
Most important hearing and ear diseases are included.
HEARING - MECHANISM, DYSFUNCTION AND TREATMENTANUGYA JAISWAL
THE DOCUMENT CONTAINS -
1.) BIOCHEMICAL AND MOLECULAR MECHANISM OF HEARING.
2.) ROLE OF VARIOUS ORGAN/SYSTEM INVOLVED IN ITS REGULATION.
3.) DYSFUNCTION OF EAR
4.) TREATMENT OF HEARING LOSS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
3. Anatomy of External ear
◦ The external ear consist of three parts
1. Auricle or pinna
2. External acoustic canal
3. Tympanic membrane
4. Anatomy and physiology of Auricle(pinna)
◦ Made up of framework of yellow elastic cartilage
◦ Projects from lateral side of the head( size, shape and angle varies)
◦ Several elevations and depressions
◦ The only visible part of the ear with its special helical shape.
◦ It is the first part of the outer ear’s anatomy that reacts to sound. The pinna’s function is to act as a kind of funnel which assists
in directing the sound further into the ear. Without this funnel the sound waves would take a more direct route into the
auditory canal. This would be both difficult and wasteful, as much of the sound would be lost, making it harder to hear and
understand the sounds.
◦ The pinna is essential due to the difference in pressure inside and outside the ear. The resistance of the air is higher inside the
ear than outside because the air inside the ear is compressed and thus under greater pressure.
5. ◦ In order for the sound waves to enter the ear in the
best possible way the resistance must not be too
high.
◦ This is where the pinna helps by overcoming the
difference in pressure inside and outside the ear.
◦ The pinna functions as a kind of intermediate link
which makes the transition smoother and less brutal
allowing more sound to pass into the auditory canal
(meatus).
6. Anatomy and physiology of External acoustic
(auditory) canal
◦ Extends from the bottom of the concha to the tympanic membrane
◦ Measures about 24mm along its posterior wall
◦ Divided into two parts
1. Cartilaginous (outer 8mm of the canal)
2. Bony (inner 16mm of the canal)
◦ Outer part is directed upward , backward and medially
◦ Inner part directed downward , forward and medially
◦ Isthmus :
The narrowest part of the ear canal (isthmus) is located near the junction of the cartilaginous and bony canals
7. ◦ Once the sound waves have passed the pinna, they move
two to three centimeters into the auditory canal before
hitting the eardrum, also known as the tympanic
membrane.
◦ The external auditory canal’s function is to transmit sound
from the pinna to the eardrum
8. Anatomy and physiology of tympanic membrane
◦ Partition between external acoustic canal and middle ear
◦ Obliquely set & its posteriosuperior part is more lateral than anterioinferior part.
◦ 9-10mm tall ,8-9mm wide & 0.1mm thick
◦ Divided into two parts
1. Pars tensa (most part of T.M periphery form ring known as annulus tympanicus )
2. Pars flaccida (sharpnell’s membrane)
◦ The eardrum is an extremely sensitive part of the outer ear anatomy. Pressure from sound
waves makes the eardrum vibrate
◦ The vibrations are then transferred to the tiny bones in the middle ear
◦ external auditory canal also functions as a natural hearing aid which automatically amplifies
low and less penetrating sounds of the human voice. In this way the ear compensates for
some of the weaknesses of the human voice, and makes it easier to hear and understand
ordinary conversation
9. Physiology of hearing
◦ In order for a sound to be transmitted to the central nervous system, the energy of the sound undergoes three transformations.
◦ First, the air vibrations are converted to vibrations of the tympanic membrane and ossicles of the middle ear. These in turn
become vibrations in the fluid within the cochlea. Finally, the fluid vibrations set up traveling waves along the basilar membrane
that stimulate the hair cells of the organ of Corti. These cells convert the sound vibrations to nerve impulses in the fibers of the
cochlear nerve, which transmits them to the brainstem, from which they are relayed, after extensive processing, to the primary
auditory area of the cerebral cortex, the ultimate Centre of the brain for hearing. Only when the nerve impulses reach this area
does the listener become aware of the sound.
◦ The human ear is most sensitive to and most easily detects frequencies of 1,000 to 4,000 hertz, but at least for normal young
ears the entire audible range of sounds extends from about 20 to 20,000 hertz
10. Diseases of external ear affecting hearing
◦ Disorders of the outer ear compromise a range of ear problems that exist or are
occurring in the external part of your ear, the pinna, the ear canal, and the eardrum
(tympanic membrane) that can lead to conductive hearing loss.
◦ Congenital disorders
◦ Anotia :
◦ complete absence of pinna and lobule i.e sound waves do not travel well through the ear and
sound is not conducted efficiently from the outer ear canal to the eardrum thus leading to
conductive hearing loss
11. ◦ Microtia :
◦ occurs in approximately one in 10,000–20,000 live births as a result of the aberrant development of the first and second branchial arches. its a congenital
deformity where in the pinna is either small, abnormally shaped, or absent. It can occur in just one side or on both sides.
◦ Leads to conductive and mixed hearing loss
◦ Atresia:
◦ is a malformation of the external ear canal. It is usually on just one side and it can be a complete or partial closure. The extent of the closure directly affects
that person’s conductive hearing loss
12. ◦ Diseases of external auditory canal
◦ Fruncle: A Furuncle is a painful infection of a hair follicle located in the ear canal. It is usually caused by staphylococcus aureus bacteria.
Hearing loss may occur when a furuncle completely occludes the ear canal leading to conductive hearing loss
◦ Impacted wax:
An accumulation of wax in the ear canal which can affect the flow of sound to the tympanic membrane. A little bit of wax is good for
the ear canal as it provides lubrication and protects the ear from bacteria and insects. Excessive cerumen can cause problems with hearing and
balance.
◦ Foreign body occlusion:
Foreign bodies can be inorganic or organic such as beans or beads, cotton tips, and even insects. It can cause trauma to the ear canal,
the tympanic membrane and even the middle ear. Leads to conductive hearing loss
wax
Foreign
body
Foreign
body and
wax
13. ◦ Exostoses:
Exostoses are benign, bony growths covered by skin. These are often seen in those who have been repeatedly exposed to cold water
(i.e. swimmers).
exostosis can completely block the ear canal causing conductive hearing los
◦ Keratosis obturans
is an obscure entity characterized by accumulation of desquamated keratinous material in the bony portion of the external auditory
canal.
Patients with this condition typically present with severe otalgia, conductive hearing loss, and global widening of the external
auditory canal.
14. ◦ Otitis externa :
is a condition that causes inflammation (redness and swelling) of the external ear canal.