Differentiated instruction is a teaching method that provides students with various learning experiences based on their individual needs and learning styles. This includes flexible grouping, where students are grouped in different configurations for different lessons. It also involves grouping students by learning style, using instructional scaffolding like mini lessons and modeling, integrating technology, and activating students' prior knowledge. When implementing these differentiated strategies, teachers should consider potential instructional issues such as time management, lack of support, labeling of students, and technical problems. An example lesson plan on plant lifecycles demonstrates how technology can be used for differentiation.