It heterogeneous metabolic disorder characterized by common feature of chronic hyperglycemia with disturbance of carbohydrate fat and protein metabolism.

1. CASE PRESENTATION
ON
DIABETES
(GERIATRIC)
PRESENTED BY..
Mr. Nitin H. Sonar
DEPT. OF CLINICAL PHARMACOLOGY
R. C. PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH, SHIRPUR. 425405

2. Definition:- As per WHO diabetes mellitus is defined as
heterogeneous metabolic disorder characterized by common
feature of chronic hyperglycemia with disturbance of
carbohydrate fat and protein metabolism .
Causes:-
Life style
Genetics factor
Obesity
Diet time variation
What is Diabetes?

3. • Insulin is a hormone made in your pancreas
• It works like a key to unlock cells so that blood sugar
(glucose) can enter
• Glucose is then used by the body as fuel
How Insulin Works

4. I. Type :-1 (insulin dependent)
II. Type :-2 (non insulin dependent)
III. Gestational diabetes
Etiological Classification of Diabetes

5. Blurred vision
Unusual thirst
Frequent urination
Slow-healing cuts
Unexplained tiredness
Rapid weight loss (Type 1 diabetes)
Numbness or tingling in hands or feet
Symptoms of Diabetes

6. Blood glucose test
Urine glucose test
Glucose tolerance test (GTT)
for screening purpose
Pathological Diagnosis

7. PATIENT DETAILS :-
Name:- : ABC.
Age :- : 65 Yrs.
Weight:- : 60 Kgs.
Sex:- : Female.
Height:- : 5 fit. 3 inch.
Address & Phone No.:- : Shirpur ; & 02563-251297
Outpatient:- : Yes.
PROFORMA

8. HOSPITAL DETAIL:-
Hospital Name:- :Radhey Hospital ,Shirpur
Consultant Name:- :Dr.Pragesh Shah ,MD(Medicine)
DOA:- :29 Jan 2015
Review Patient:- :25 Feb 2015
Continue…

9. SOCIAL HISTORY:-
: Non-Alcohol
: Non-Smoker
: Vegetarian
: Obey
FAMILY HISTORY:-
: None
DIAGNOSIS:-
: Diabetes mellitus Type-II
ASSOCIATE DISEASE:-
: Hyper tension
Continue…

10. Hematological Investigation:-
 Fasting:-
Post Meal:-
Laboratory Investigation
Fasting Period Result
(mg%)
Normal Value
(mg%)
Blood sugar 155 70-110
Post Meal Result
(mg%)
Normal Value
(mg%)
Blood sugar 197 70-140

11.  Urine Analysis :-
 Physical Investigation:-
Qnty.:- : 10 ml
Color:- : Yellow
Appearance:- : Clear
Odor:- : Aromatic
 Chemical investigation:-
Sugar:- : ++++
bile salt:- : Nil
Albumin:- : Nil
Continue…

12. Prescribed Medication
Sr.No. BRAND NAME API DOSE FREQUENCY CATEGORY
1 Tab.Glynose-MF
Glipizide
Metformin HCL
5 mg.
500 mg. TD
Anti hyperglycemic
2
Tab.Voglistar-MD
0.3
Voglibose IP
0.3 mg. TD
3 Tab.Piokind-15 Pioglitazone 15 mg. OD
Oral hyperglycemic
4 Tab.Olmetime-20
Olmesartan
medoximil
20 mg. OD Anti-hypertension
5 Tab.Corbis-2.5 Bisoprolol 2.5 mg. OD β1-Selective blocker
6 Tab.DLX-20 Duloxetine HCL 20 mg.
OD
Anti-depressant
7 Cap.Neurotrate
Chromium
Zinc
Vit.B complex
500 mg.
OD
Multi Vitamin
8 Tab.Vysow-M
Vildagliptin
Metformin HCL
50 mg.
500 mg.
OD
Oral hyperglycemic

13. Suppress the hepatic gluconeogenesis and glucose
output from liver the major action .
enhance insulin mediated glucose disposal in
muscle and fat . Through the do not alter translation of
GLUT4 they enhance GLUT1 transport from the
intracellular site to plasma membrane,
MOA of Metformin

14. METFORMIN:-
Depression
Mental Disturbances
Dizziness
GLIPIZIDE:-
Increased Hunger
Blurred Vision
Confusion
Duloxetine HCL:-
Muscle Aches
Dry Mouth
Weight loss
ADR’S Of Drug’s

15. • Glipizide are acting on β-cell's of pancreas organ and
Insulin secretion are increase.
MOA of Glipizide

16. • Glipizide interact with Corticosteriods,Furosemide,
Oral-contraceptives are suppress Insulin secretion.
• Avoid drinking alcohol. It lowers blood sugar and may
interfere with your diabetes treatment.
Drug-Drug Interaction

17.  Check your feet every day,
Look for cuts, blisters, red spots, swelling.
 Wash your feet every day in warm (not hot) water,
Dry well, especially between the toes.
 Never walk barefoot.
 Keep your blood sugars in good control.
Patient Counseling

18. Tripathi K.D, 2004 , “ Essential Of Medical
Pharmacology”, 6th Edition , Jaypee Publication
Page No: 254,266-269.
Harsh Mohan ,2010 , “Textbook Of Pathology”, 6th
Edition , Jaypee Publication ,Page No:818, 825-828.
www.drugdigest.com
Reference's