Dexona (Generic Dexamethasone Tablets) is a synthetic corticosteroid exhibiting both anti-inflammatory and immuno-suppressant properties. This medication is used to treat symptoms such as inflammation, certain immune disorders and in replacement therapy of an inactive or underactive adrenal gland. Generic Dexamethasone can be prescribed for skin allergies, asthma, leukaemia, blood disorders, selected rheumatic disorders, gastrointestinal disorders, skin problems, certain abnormal growths (cancers) and excessive calcium in the blood.

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Dexona Tablets (Generic Dexamethasone Tablets)

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Dexona Tablets (Generic Dexamethasone Tablets)
Dexona (Generic Dexamethasone Tablets) is a synthetic
corticosteroid exhibiting both anti-inflammatory and
immuno-suppressant properties. This medication is used to
treat symptoms such as inflammation, certain immune
disorders and in replacement therapy of an inactive or
underactive adrenal gland.
Generic Dexamethasone can be prescribed for skin allergies,
asthma, leukaemia, blood disorders, selected rheumatic
disorders, gastrointestinal disorders, skin problems, certain
abnormal growths (cancers) and excessive calcium in the
blood.

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Dexona Tablets (Generic Dexamethasone Tablets)
Active Ingredient
The active ingredient present in Dexona
tablets is Dexamethasone Sodium
Phosphate. Each Dexona tablet contains 0.5
mg of Dexamethasone.

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Dexona Tablets (Generic Dexamethasone Tablets)
Chemical Structure
The structure of Dexamethasone is given below:

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Dexona Tablets (Generic Dexamethasone Tablets)
Dexona tablets are manufactured by Zydus Alidac, a
division of Zydus Cadila Healthcare Limited, India in the
strength of 0.5 mg.
(Website: https://www.zyduscadila.com/ )
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Dexona Tablets (Generic Dexamethasone Tablets)
Dexamethasone Tablets – Brand Names
Dexamethasone tablets are available under
various drug trade names that include
Dexona, Demisone, Dexamag, Dexasone,
Dexane.

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Dexona Tablets (Generic Dexamethasone Tablets)
Uses of Dexona Tablets
Dexona (Generic Dexamethasone tablets) provides relief for inflamed
areas of the body. It is used to treat a number of different conditions, such
as inflammation (swelling), severe allergies, adrenal problems, arthritis,
asthma, blood or bone marrow problems, kidney problems, skin
conditions, and flare-ups of multiple sclerosis.
Dexamethasone is a corticosteroid (cortisone-like medicine or steroid). It
works on the immune system to help relieve swelling, redness, itching, and
allergic reactions.
Dexamethasone tablets are also used in combination with other anti-
myeloma products for the treatment of adults with multiple myeloma.
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Dexona Tablets (Generic Dexamethasone Tablets)
Dexona Tablets Dosage
The dosage of Dexona tablets (Generic Dexamethasone
Tablets) is given below:
The recommended initial oral dosage of Generic Dexamethasone tablets
varies from 0.75 to 9 mg a day depending on the indication being treated.
It must be emphasized that dosage requirements are variable and must be
individualized on the basis of the disease under treatment and the response of
the patient.
After a favorable response is noted, the proper maintenance dosage should be
determined by decreasing the initial drug dosage in small decrements at
appropriate time intervals until the lowest dosage that maintains an adequate
clinical response is reached.
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Dexona Tablets (Generic Dexamethasone Tablets)
Dexona Tablets Contraindications
Dexona tablets are contraindicated in persons with a
hypersensitivity (allergy) to Dexamethasone Sodium Phosphate
or any of the other ingredients of this medicine.
They are also contraindicated in patients with systemic fungal
infections unless specific anti-infective therapy is given. Live
virus immunisation must not be carried out in patients
undergoing therapy with this medicine since serum antibody
response diminished.
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Dexona Tablets (Generic Dexamethasone Tablets)
Storage Instructions
Dexona Tablets (Generic Dexamethasone
Tablets) have to be stored at controlled room
temperature i.e. from 20°C to 25°C (68°F to
77°F) with excursions permitted between 15° to
30°C (59° to 86°F).
Keep this as well as all other medicines away
from children and pets.
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Dexona Tablets (Generic Dexamethasone Tablets)
Warnings
Alterations in Endocrine Function: Hypothalamic-pituitary adrenal (HPA)
axis suppression, Cushing’s syndrome, and hyperglycemia can occur.
Monitor patients for these conditions with chronic use.
Immunosuppression and Increased Risk of Infections: Increased risk of
new, exacerbation, dissemination, or reactivation of latent infections.
Alteration in Cardiovascular/Renal Function: Monitor for elevated blood
pressure and sodium, and for decreased potassium levels.
Venous and Arterial Thromboembolism: Risk increased; consider
anticoagulant prophylaxis and monitor for evidence of thromboembolism.
Vaccination: Avoid the administration of live or live attenuated vaccines in
patients receiving immunosuppressive doses of corticosteroids.
Ophthalmic Effects: May include cataracts, infections, and glaucoma.

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Dexona Tablets (Generic Dexamethasone Tablets)
Warnings
Gastrointestinal Perforation: Avoid use in active or latent peptic ulcers,
diverticulitis, fresh intestinal anastomoses, and nonspecific ulcerative
colitis, since they may increase the risk of a perforation.
Osteoporosis: Increased risk; monitor for changes in bone density with
chronic use.
Behavioral and Mood Disturbances: May include euphoria, insomnia,
mood swings, personality changes, severe depression, and psychosis.
Monitor for signs and symptoms and manage promptly.
Kaposi’s Sarcoma: Kaposi’s sarcoma has been reported to occur in patients
receiving corticosteroid therapy, most often for chronic conditions.
Embryo-Fetal Toxicity: Can cause fetal harm. Advise females of
reproductive potential of the potential risk to a fetus.

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Dexona Tablets (Generic Dexamethasone Tablets)
Side Effects
The most common Dexamethasone (Dexona tablets) side
effects are cardiovascular, dermatologic, endocrine, fluid
and electrolyte disturbances, gastrointestinal, metabolic,
musculoskeletal, neurological/psychiatric, ophthalmic,
abnormal fat deposits, decreased resistance to infection,
hiccups, increased or decreased motility and number of
spermatozoa, malaise, moon face, and weight gain.
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Dexona Tablets (Generic Dexamethasone Tablets)
Dexone Tablets Overdose
Treatment of Dexamethasone overdosage is by
supportive and symptomatic therapy.
In the case of acute overdosage, according to the patient's
condition, supportive therapy may include gastric lavage
or emesis.
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Dexona Tablets (Generic Dexamethasone Tablets)
Dexona Tablets During Pregnancy
Dexamethasone (Dexona tablets) has been classified by the US FDA as
Pregnancy Category C.
Corticosteroids, including Dexamethasone, readily cross the placenta. Adverse developmental
outcomes including orofacial clefts (cleft lip with or without cleft palate), intrauterine growth
restriction, and decreased birth weight have been reported with maternal use of
corticosteroids, including Dexamethasone, during pregnancy. In animal developmental and
reproductive toxicology studies administration of corticosteroids to pregnant animals during
organogenesis resulted in structural abnormalities, embryo-fetal mortality, functional
impairment, and alterations to growth at doses equivalent to or below the recommended
doses.
Advise pregnant women of the potential risk to a fetus. As with all medications,
corticosteroids should only be prescribed when the benefits to the mother and child
outweigh the risks.
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Dexona Tablets (Generic Dexamethasone Tablets)
For more details on
Dexona Tablets click here
Dexona Tablets (Generic Dexamethasone Tablets) by Zydus Alidac,
A division of Zydus Cadila Healthcare Limited, India.
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