Deerghayushkara rasayan drugs (2) pdf (1)

Concepts of Rasayan
and
Deerghayushkara rasayana
drugs
Dr. RASHMI SRIVASTAVA
MD. Ph.D.
READER, DEPT. OF DRAVYAGUNA
RGGPG AYURVEDIC COLLEGE, PAPROLA, H.P.

DEERGHAYUSHKARA RASAYANA DRUGS
RASAYANA
DEERGHAYUSHKARA
DRUGS

RASAYANA- ROOT MEANING
 is composed of two words
Rasa + Ayaan
 RASA : Rasa, Raktadi Dhatu
 AYANA : Means to achieve
 Rasayana literally means the method or
measures by which one can obtain the best
qualities of Dhatus or Tissues.

IN SHODASANGA HRIDAYAM, RASAYANA
IS MENTIONED AS ONE AMONG SIXTEEN
BRANCHES OF AYURVEDA
iz;kstua pkL; LoLFkL; LokLF;j{k.kekrqjL; fodkjiz’keua
p A p lw 30@26
Primary objective of health care is
prevention of disease & promotion of
health

References
 nh/kZek;%q Le`fra es/kkekjksX;a r#.ka o;% A
izHkko.kZLojkSnk;Za nsgsfUnz;cya ije~ AA
okfDLkf)a iz.kfra dkfUra yHkrs uk jlk;ukr~ A
ykÒ®ik;® gh ’kLrkuka jlknhuka jlk;ua AA
¼p fp 1@7&8½
 jlk;ua p rTKs;a ;TtjkO;kf| uk’kuea A
¼’kk³~Zx/kj½
 ;TtjkO;kf/k fo/oafl Òs"kta rn~jlk;ua AA
¼HkS j½
 o;% LFkS;Zdjk.kkEk¸kua ykÒ®ik¸kks jlk;ue~ A
¼VYg.k½

DEFINITION OF RASAYANA BY DIFFERENT
ACHARYAS
 Charaka
 Rasayana is the means for attaining a disease free
state, gaining youthfulness and hence longevity. It
also improves memory and intelligence along with
lustre, complexion and voice. It promotes physical
strength and maintains healthy sense organs. All
these are achieved by the attainment of excellent
dhatus.
ref.- ch.chi.1/78

Cont.…
 Susruta
 Susruta has defined rasayana in Ashtanga
Ayurveda as a branch that improve longevity along
with physical and mental strength and immunity.
Ref.- su.su.1/15
 Chakrapani datta
 rasayana averts senility and diseases.
 Sharngadhara
 Similar view is given by him that rasayana act as
anti ageing and immunity promoting

AHARA RASAYANA (Dietary rasayana)
VIHARA RASAYANA (Code of conduct )
AUSADHA RASAYAN (Drug rasayana)
AS PER CONTENT OF RASAYANA

Benefits of RASAYANA
nh/kZek;q% increases longevity
Le`fr% enhances memory
es/kk promoting intellect
vkjksX;a preventing diseases
r#.ka o;% youthfulness
izHkko.kZ enhances complexion/lustre
LojkSnk;Z tone up speech and vocal cord
nsgsfUnz;Ckya enhances physical strength and tone up the
sensory and motor organs
okfDLkf)% truthfulness
dkfUr% increases the glow (Ch. Chi. 1/8)

Resistance against diseases
Improvement in bodily strength and mental faculties
Prevention of ageing
RASAYANA is a branch of Ayurvedic medicine which improves the
fundamental tissues like Dhatu, Agni, Srotas etc. of human body
leading to
LoLFkL;kstZLdja ;Rrq rn~ o`";a rnzlk;ue~A

MECHANISM OF ACTION AS PER
AYURVEDA
RASAYANA
RASA AGNI SROTAS DRAVYA PRABHAV
By improving
the nutritional
value of
plasma
by improving
metabolic
activities
by improving
microcirculation
Due to specific
potency of the
drugs
All these lead to improved nourishment
Improved quality of tissues
ykÒ®ik;® gh ’kLrkuka jlknhuka jlk;ua

Scope of Rasayana
tjkfuoZrd O;kf/kfuorZd Izk’kLr/kkrqtud nh?kkZ;q"dj
Prevents
Senile
Degenerat
ion
Prevents
/Cures
Diseases
Keeps
Body
Tissue
Healthy
Provides
Longevity
Preventive Curative Promotive
vktfJd
jlk;u
nqX/k ?k`rkH;kl
uSfefÙkd jlk;u
lfiZxqM-&{kr{kh.k
;ksxjkt jlk;u & ik.Mq
vxLR; gjhrdh &dkl
P;ouizk’k & dkl
dkE; jlk;u

Functions of kamya rasayana
KAMYA RASAYAN
• PRANAKAMYA-
• izk.kk;qcZyoh;ksZtLdjks ÒofUr ¼lq lw 6@17½
• MEDHAKAMYA-
• es/kk;S vfr’k;su fgre~ ¼p lw 27@64½
• SRIKAMYA

Srikamya
Wholesome drugs may consider under Srikamya Deerghayushkara
drugs which is beneficial for the quality of life along with extension of
life span
 o.;Z% & o.kkZ; fgr% A
 Pk{kq";e~ & p{kq"ks fgra p{kq";e~ A
nk#gfjnzk us=;ks% ija fgre~ A
 d.B~;e~ & d.Bk; fgre~ A
 ds’;% & ds’ksH;ks fgr% A
 Thouh;% & izk.k’kfDroèkZuh;% A
 cY;% & cyk; fgrks cY;% A
 â|e~ & #P;e~++] ân;k; fgre~ A
(Dravyagunakosah)

DIFFERENT PERSPECTIVES OF KAMYA
RASAYANA
 {khja thouh;kuke~
 jlLriZ.kh;kuke~
 vEya â|kuke~
 vkeyda o;LFkkiukuke~
 gjhrdh iF;kuke~
 {khj?k`rkH;klks jlk;ukuke~
 O;k;ke% LFkS;Zdjk.kke~
 g"kZ% izh.kukuke~ (ch. su. Chapter 25)

HRIDYA MAHAKASHAYA
 vkezkezkrdfydqpdjenZo`{kkEykEyosrldqoycnjnkfMeekrqyq³xkuhfr
n’ksekfu â|kfu HkofUr A ¼p lw 4@10½
 Amra, Amrataka, Likucha, Karamarda, Vrikshamla,
Amlavetasa, Kuvala, Badara, Dadima, matulunga

Giving emphasis on PARA OJAS
rUegr~ rk egkewykLrPpkSt% ifjj{krk A
ifjgk;Zk fo’ks"ks.k eulks nq%[kgsro% AA
â|a ;r~ L;k|nkStL;a lzksrlka ;r~ izlknue~ A
rRrr~ lsO;a iz;Rusu iz’keks Kkueso p AA
¼p lw 30@13&14½

Why deerghayushkara drugs are needed??
By the rasayana therapy, improvement of both physical and
mental faculties can be achieved
And the ojas of the person decreases
As a result, all the seven dhatus become abnormal
Unhealthy food, irregular and improper routine and mental
perturbations like bhaya (fear), krodha (anger), shoka (grief), lobha
(greed), moha (attachment), ayasa (confusion) etc cause all types of
morbidities

Interpretation….
OXIDATIVE DAMAGE OF THE CELLS
AGE RELATED PROBLEMS DEVELOP
neurohormonal secretions disturbed
more free radicals formation
Disturbance in balance of anabolism and catabolism

 Ageing is a phenomena which indicates that as one is
growing older, he is loosing his age or nearing death-
the end of life
 Specifically refers to; biological ageing
 Biological ageing is a complex process associated
with accumulated cellular damage by environmental
or genetic factors with increasing age
AGEING

OLD AGE DISEASE
 Pertaining to the physical decline
 Pertaining to the mental decline
1. Bones and joints/ ligaments- reduced bone mineral
density, osteoporosis, delayed union of fractured bones,
degenerative arthritis
2. Nutritional disorders
3. Metabolic disorders
4. Degenerative disorders- RA, Atherosclerosis,
Parkinsonism, Alzheimer’s disease

AYURVEDIC PERSPECTIVE OF
DEERGHAYU
 Some Acharyas mentioned that; we can’t increase the life
span of an individual, as it is already fixed in our classics
but can delay the process of ageing with quality of life
 Susruta described many Rasayana formulations that
increase the life span and refers them as Ayushkara
 Vayasthapana and Ayushkara are just one aspect of the
broad acting Rasayana drugs
 Prof. P.V. Sharma in Ayurveda darsanam quotes
srimadbhagawat verse, where rasayana is described as
‘o;ks:ikfHkyEcue~‘
the means of delaying the process of ageing and retaining
the beauty

 Dalhana explains that Vayasthapana indicates retardation
of the process of ageing and maintaining a life span of 100
years, whereas Ayushkara drugs increase the life span
beyond 100 years
 It has been repeatedly mentioned by all Acharyas that;
Rasayana increases the life span of the person and prevents
premature ageing and different diseases

ACHARYA SHARNGADHARA’S VIEW
 Drugs used for promotive purposes according to age
DECADE OF LIFE LOSS OF IMPACT/
DESIRED EFFECT
DESIRABLE
RASAYANAS
1-10 Baalya Vacha, Swarna
11-20 Vridhi Kashmari, Bala
21-30 Chavi Amalaki, Lauha
31-40 Medha Shankhapushpi
41-50 Tvak Jyotishmati
51-60 Drishti Jyotishmati
61-70 Shukra Atmagupta,
Aswagandha
71-80 Vikrama Amalaki, Bala
81-90 Budhi Brahmi
91-100 Karmendriya Bala rasayana

RECENT RESEARCH SUGGESTS…
 INCREASE IN DROSOPHILA MELANOGASTER
LONGEVITY DUE TO RASAYANA DIET:
Preliminary results
Data indicating life span extensions of 51-55% (upto
70-95% in the pilot experiment) in a standard strain of
Drosophila melanogaster (Oregon-K) using a standard
Rasayana (Ayurvedic herbal formulation for life
extension) suitably adapted for insects
S. Priyadarshini, J.S. Ashadevi, V. Nagarjun, K.S. Prasanna
Journal of Ayurveda and integrative
medicine1(2),114, 2010

CONT…
 According to Ayurveda, human body consists of
seven constituents (sapthadhatus). The dhatus get
degenerated due to the body’s prolonged structural
changes. During old age we cannot enhance the
capacity of dhatus, but can only provide quality of
life
 For longevity - disease free state is necessary, which
can be obtained by imparting deerkhayushkara
rasayana drugs in day to day life
 By this prathama prayojana of Ayurveda will be
fulfilled

Rasayana Drugs acting on specific Dhatu
 Rasa – Draksha, Kashmari, Kharjur
 Rakta – Amalaki, Bhringraj, Palandu, Lauha
 Mamsa – Ashwagandha, Shalparni
 Meda – Guggulu, Shilajeet, Haritaki,Amrita
 Asthi –Shankha, Shukti, Laksha, Vanshalochana,
Prishniparni
 Majja – Lauh, Vasa, Majja
 Shukra – Atmagupta, Nagabala

OJA PRAPTI
jlknhuka 'kqdzkUrkuka /kkrwuka ;r~ ija rst%+&&&&CkyfeR;qP;rs AA
lq lw 15@24
 Ojas – drugs which have similar qualities to
that of ojas (all the madhura rasa, madhura
vipaka and sheeta virya dravyas which
contain primary metabolites)

Deerghayushkara Rasayana Drugs
Bala, Kashmari & Varahi act as dietary adjuvants & are good for increasing the strength
of tissues and organs
Pippali acts as “Respiratory Rasayana “
Lahsun increases the tissue enzymes
Brahmi, Vacha ,Shankhapushpi, Mandukaparni helps to increase intellect and
memory.
Guggul helps further digestion of waste products.
Amlaki and Guduchi decrease the catabolic process and thus postpone ageing. Therefore
they are “Vayasthapak Rasayana “( Adaptogenic tonic )

Cont.…
Bhallataka has a powerful immune promoting substance which
overcomes many conditions like RA & some sages of malignanacy
Punarnava promotes the kidney functions and improves the
regenerating capacity of nephrons
Shatavari is best known as a female rejuvenative drug
Haritaki act as “Digestive Rasayana “ by eliminating the
waste products from the tissue, particularly from GIT

Rasayana drugs in different fields…. as
deerghayushkara
IN BRAIN AGEING
▪ In terms of the science of today, human brain
is a highly sophisticated structure
▪ Its basic functional units- the neurons are
known to be energetically most powerful
units but have extremely poor repair and
regeneration potential
▪ Hence are prone to rapid senescence and
degenerative changes

Some rasayana Drugs acts on brain ageing
Mandukaparni
Yashtimadhu
Guduchi
Shankapushpi
Jyotishmati
Vacha
Kushmanda
Jatamansi
Aindri
Ashwagandha

DRUG RASA GUNA VEERYA VIPAKA
MANDUKPARNI TIKTA LAGHU SHEETA MADHURA
YASHTIMADHU
MADHUR GURU
SNIGDHA
SHEETA MADHURA
GUDUCHI
TIKTA,
KASHAYA
GURU, SNIGDHA USHNA MADHURA
SHANKHPUSHPI
TIKTA SNIGDHA, PICCHIL SHEETA MADHURA
JYOTISHMATI
KATU,
TIKTA
TIKSHNA USHNA KATU

VACHA KATU
TIKTA
LAGHU,
TEEKSHNA
USHNA KATU
KUSHMANDA MADHUR LAGHU
SNIGDHA
SHEET MADHUR
JATAMANSI TIKTA,
KASHAYA,
MADHUR
LAGHU
SNIGDHA
SHEET KATU
AINDRI TIKTA LAGHU USHNA KATU
ASHWAGANDHA MADHUR LAGHU,
SNIGDHA
USHNA MADHUR

Classical reference
MEDHYA RASAYANA
 esËkk;S fgre~] esËkkoËkZdfeR;FkZ% ¼nzO;xq.kdks’k½
e.Mwdi.;kZ% Lojl% ç;ksT;% {khjs.k ;"Vhe/kqdL; pw.kZe~A
jlks xqMwP;kLrq lewyiq"I;k% dYd% ç;ksT; [kyq 'ka[kiq"ihAA
vk;q% çnkU;ke;uk’kukfu cykfXuo.kZLojo/kZukfuA
es/;kfu pSrkfu jlk;ukfu es/;k fo’ks"ks.k p ’ka[kiq"ihAA
bfr es/kkdj jlk;ukfuA
.

MANDUKAPARNI
 es/kkoh o"kZ’krk;qÒZofr AA ¼lq fp 28½
 Chemical constituent
The constituent responsible is asiaticoside
 Properties
This is a triterpene which is neuro protective and has
antioxidant properties

YASHTIMADHU
The major constituent useful in brain function is
glabridin
Chemically, it is a flavonoid polyphenol, which is
proven to attenuate cerebral injuries in stroke as it is
neuro protective
 Properties
It is also proved in animal studies that it enhances
memory retention, thus it is useful in Alzheimer's
disease

GUDUCHI
 ve`rk∙e`ror~ xq.kçÒok p A ¼fiz fu½
 Botanical name- Tinospora cordifolia
 Family- Menispermaceae
 Part used- stem, root, flowers
 Chemical constituents- berberine, giloin, rich source
of trace elements (Zn, Cu)
 Rasapanchaka –
Guna - guru, snigdha
Rasa- tikta, kashaya
Vipaka- madhura
Virya- ushna

Properties
 Acts as antioxidants and protect cells from the damaging
effects of free radicals generated during immune activation
 The major constituents of guduchi is berberine,
 It is a isoquinolone alkaloid that has acetyl cholinesterase
inhibitory action,
 Berberin helps to prevent oxidative damage to bio-
molecules of brain, reduces peptides that interfere with
memory function and lowers lipids that hamper cerebral
blood flow
 So, guduchi arrests neuro degeneration which is commonly
present in Alzheimer's disease

SHANKHAPUSHPI
Convolvulus pleuricaulis having chemical constituent
convolvuline which is responsible for blocking M2 and
M4 cholinergic muscarinic receptors
 Properties
It potentiates the effect of arecoline
It enhances memory by ameliorating cognitive
defects in Alzheimer's disease

Ukke jl xq.k oh;Z foikd
,sUæh
Scrophulariaceae
Bacopa monnieri
frDr yÄq m".k dVq
T;ksfr"efr
Celastraceae
Celastrus peniculatus
dVq] frDr rh{.k m".k dVq
opk
Araceae
Acorus calamus
dVq] frDr yÄq] rh{.k m".k dVq
/kh ¼cqf++)½ o/kZd jlk;u nzO; ,oa Le`fr o/kZd nzO; (memory
enhancer and intellect promoting drugs)

/k`fr o/kZd jlk;u nzO; ¼retention of memory)
e.Mwdi.khZ
Umbelliferae
Centella asiatica
frDr] d"kk; yÄq ’khr e/kqj
’ka[kiq"ih
Convulvulaceae
Convolvulus pluricaulis
frDr fLuX/k] fifPNy ’khr e/kqj
dw"ek.M
Cucurbitaceae
Benincasa hispida
e/kqj yÄq] fLuX/k ’khr e/kqj
eqysBh
Leguminosae
Glycyrrhiza glabra
e/kqj xq:] fLuX/k ’khr e/kqj
vkEkydh
Euphorbiaceae
Emblica officinalis
Ikapjl
¼vEy ç/kku½
Xq:] :{k ’khr e/kqj

vkstkso/kZd jlk;u o cY; jlk;u (immunity boosters)
cyk
Malvaceae
Sida cordifolia
e/kqj yÄq] fLuX/k] fifPNy ’khr e/kqj
vfrcyk
Malvaceae
Abutilon indicum
egkcyk
Malvaceae
Sida rhombifolia
jktcyk
Malvaceae
Sida veronicefolia
fonkjh
Leguminosae
Pueraria tuberosa
e/kqj yÄq] fLuX/k ’khr e/kqj
Okkjkgh dUn
Dioscoreaceae
Dioscorea bulbifera
dVq] frDr]
d"kk;
yÄq] fLuX/k m".k dVq

cY; jlk;u (strength promoters)
thoUrh e/kqj yÄq] fLuX/k] ’khr e/kqj
Eqkn~xi.khZ e/kqj yÄq] :{k ’khr e/kqj
Ekk"ki.khZ e/kqj] frDr yÄq] fLuX/k ’khr e/kqj
v’oxa/kk e/kqj] frDr yÄq] fLuX/k ’khr e/kqj
ukxcyk e/kqj] d"kk; xq:]fLuX/k] fifPNy ’khr e/kqj
Ukxneu e/kqj fLuX/k] fifPNy ’khr e/kqj
’kkyi.khZ e/kqj] frDr xq:] fLuX/k m".k e/kqj
i`f’ui.khZ e/kqj] frDr xq:] fLuX/k m".k e/kqj

/kkrqiks"kd jlk;u nzO; (tissue enhancers)
Ä`r e/kqj xq:] fLuX/k] ’khr e/kqj
nqX/k e/kqj xq:] fLuX/k ’khr e/kqj
’krkojh e/kqj] frDr xq:] fLuX/k ’khr e/kqj
[ktqZj e/kqj xq:] fLuX/k ’khr e/kqj
æk{kk e/kqj fLuX/k] xq:] e`nq ’khr e/kqj

vfXu ¼atBjkfXu o /kkRokfXu½ ds Lrj ij (digestives)
fiIiyh dVq yÄq]fLuX/k] rh{.k vuq".k’khr e/kqj
fp=d dVq yÄq] :{k] rh{.k m".k dVq
fgaxq dVq yÄq] fLuX/k]rh{.k m".k dVq
HkYykrd dVq]frDr] d"kk; yÄq]fLuX/k] rh{.k m".k e/kqj
Ä`r dqekjh dVq] frDr xq:]fLuX/k]
fifPNy
m".k dVq

lzksrksa ds Lrj ij
efjp
Piperaceae
Piper nigrum
dVq yÄq]rh{.k m".k dVq
gjhrdh
Combretaceae
Terminalia chebula
iapjl yÄq] :{k m".k e/kqj
HkYykrd
Anacardiaceae
Semecarpus anacardium
dVq] frDr d"kk; yÄq] fLuX/k] rh{.k m".k e/kqj
xqXxqy
Burseraceae
Commiphora mukul
frDr] dVq yÄq] :{k] rh{.k]
fo’kn] lw{e] lj
m".k dVq
jlksu
Liliaceae
Allium sativum
Iakpjl fLuX/k]rh{.k] fifPNy m".k dVq

okr izd`fr ds vuqlkj jlk;u nzO;
v’oxa/kk
Solanaceae
Withania somnifera
frDr]dVq] e/kqj yÄq] fLuX/k m".k e/kqj
xqMwph
Menispermaceae
Tinospora cordifolia
frDr fLuX/k] fifPNy m".k e/kqj

fiRr izd`fr iq#"k esa ykHkdkjh jlk;u nzO;
vkeydh
Euphorbiaceae
Emblica
officinalis
iapjl xq:] :{k ’khr e/kqj
’krkojh
Liliaceae
Asparagus
racemosus
e/kqj] frDr xq:] fLuX/k ’khr e/kqj

dQ çd`fr iq#"k esa ykÒdkjh jlk;u nzO;
HkYykrd
Anacardiaceae
Semecarpus anacardium
dVq]frDr] d"kk; yÄq]fLuX/k] rh{.k m".k e/kqj
jlksu
Liliaceae
Allium sativum
Iakpjl fLuX/k m".k dVq
fiIiyh
Piperaceae
Piper longum
dVq yÄq]fLuX/k] rh{.k vuq".k’khr e/kqj
xqXxqy
Burseraceae
Commiphora mukul
frDr] dVq yÄq]:{k]rh{.k]
fo’kn lw{e
m".k dVq

Probable mode of action of deerghayushkara
drugs- Ayurvedic perspective
 From the above table, it is clear that most of the drugs of
rasayana property; are having madhura rasa, madhura
vipaka and sheeta virya
 Having brimhana/anabolic property; they nourish each
dhatu leading to the formation of excellent essence i.e. ojas
 Thereby increases vyadhikshamatwa (immunity against
diseases)
 Those dravyas which are having katu rasa, ushna virya, also
acts as rasayana by their specific agni deepana and sroto
shodhana properties
 In this way, the aim of Ayurveda is fulfilled

Deerkhayushkara rasayana dravyas- in
modern perspective
❑Immunomodulators
❑Antioxidants
❑Primary metabolites

IMMUNO MODULATOR
❑Chronic stress has an immunosuppressive action
which adversely affects the defense mechanism of
the body by producing OFRs
 One of the major use of Rasayan drug is modulation
of the immune response
 The difference between rasayana drugs and immuno
stimulants is that the former appear to optimize the
immune system only when it is compromised. They
have been shown to influence both cellular and
humoural immunity by acting on immune function
mediators

ANTI-OXIDANTS
 Oxidation is chemical reaction that can produce free
radicals, leads to chain reactions; that may damage
the cells.
 Anti-oxidant is a molecule that inhibits the oxidation
of other molecules and neutralize the damage caused
by free radicals
 Prevents age related diseases and improve the
quality of life of an aged one

FLAVONOIDS
 Flavonoids are a group of plant metabolites though
to provide health benefits through cell signaling
pathways and anti oxidant effects
 Flavonoids have great potential to inhibit the
generation of reactive oxygen species (ROS) and
reduce the levels of ROS

❑In animal models and clinical trials, several
rasayana drugs are showing antioxidant and
Immuno-modulator activity. Rasayana drugs
retard the process of ageing probably by
acting as free radical scavenger and by
enhancing the immune status of the body.
(Arora et al.,1999)

PRIMARY METABOLITES
 Primary metabolites is a kind of metabolite that is directly
involved in normal growth, development, and
reproduction and perform the physiological function in
an organism
 Comprises carbohydrates, lipids, proteins, vitamins, lactic
acid etc
 Eg: Varahi - o"kZ’krek;qjokIuksfr AA
Vidari - o`)®∙fi r#.kk;rs AA
Shanaphala- o;LrL; u ’kh;Zrs AA ¼ lq fp½
Gambhari- ds’;a jlk;ua es/;e~ AA ¼ lq lw ½

RASAYANA DRUGS WITH IMMUNO-
MODULATORY ACTIVITY
Aconitum heterophyllum Holarrhena antidysentrica
Aloe vera Mangifera indica
Asparagus racemosus Picrorrhiza kurroa
Andrographis paniculata Piper longum
Allium sativum Randia dumatorum
Curcuma longa Shilajit
Gmelina arborea Sphaeranthus indicus
Glycyrrhiza glabra Tinospora cordifolia
Hemidesmus indicus Withania somnifera

RASAYANA DRUGS WITH ANTIOXIDANT
ACTIVITY
Asparagus racemosus Piper longum
Bacopa monnieri Tinospora cordifolia
Boerrhavia diffusa Picrorrhiza kurroa
Centella asiatica Curcuma longa
Convolvulus pluricaulis Shilajit
Witania somnifera
Emblica officinalis

AMALAKI AMLA GURU,RUKSHA SHEET MADHUR
ASHWAGANDHA MADHUR LAGHU,SNIGDHA USHNA MADHUR
BALA MADHUR LAGHU,SNIGDHA SHEET MADHUR
GUDUCHI TIKTA GURU, SNIGDHA USHNA MADHUR
GOKSHURA MADHUR GURU,SNIGDHA SHEET MADHUR
GUGGULU TIKTA,
KATU
SNIGDHA,PICHILA USHNA KATU
HARITAKI KASHAYA
PRADHAN
LAGHU,RUKSHA USHNA MADHUR

PUNARNAVA MADHUR
TIKTA
LAGHU
RUKSHA
USHNA MADHUR
SHALIPARNI MADHUR
TIKTA
GURU
SNIGDHA
USHNA MADHUR
PIPPALI KATU LAGHU
SNIGDHA
TIKSHNA
ANUSHNAS
HEET
MADHUR
SHATAVARI MADHUR
TIKTA
GURU
SNIGDHA
SHEET MADHUR
VIDARIGANDHA MADHUR
TIKTA
GURU
SNIGDHA
USHNA MADHUR

PROPERTIES OF SOME
DEERGHAYUSHKARA DRUGS
1. Amalaki
2. Bibhitaki
3. Haritaki
4. Pippali
5. Gambhari
6. Bala
7. Eranda
8. Bilwa
9. Shatavari
10. Ashwagandha
11. Gokshura
12. Punarnava
13. Amlavetas
14. Tagar

AMALAKI
o;LFkkiukuke~
 Botanical name- Emblica officinalis
 Family- Euphorbeaceae
 Part used- fruit, seed
 Chemical constituents- phyllemblin, ascorbic acid
(Vit C), Gallic acid, tannins, pectin
 Rasapanchaka-
Rasa- Lavana rahita pancha rasa
Guna- Guru, Ruksha, Sheeta
Vipaka- Madhura
Virya- Sheeta

 As rasayana-
Amalaka rasayana (Ch. Chi 1.2.8 also 1.1.58-74)
For maintaining youthfulness amalaka is the best one.
(AH.U.40.56)
o Properties
Strong antioxidant and anti-ageing agent, stimulating hair
growth

o Recent research
o The health benefits of Indian Traditional Ayurvedic Rasayana
Drugs including Amalaki Rasayana;
o Including free radical scavenging, prevention of lipid
peroxidation, inhibition of DNA damage, and protection and
rapid regeneration of bone marrow stem cells, increase/
restoration of antioxidants
Manjeshwar Shrinath Baliga, Raghavendra Haniadka
Foods and Dietary Supplements in the Prevention and Treatment of Disease in
Older Adults, 2015

BIBHITAKI
 Botanical name- Terminalia bellirica
 Family- Combretaceae
 Part used- fruit, seed
 Chemical constituents- chebulinic acid, chebulagic acid,
corilagin, tannins, ellagic acid, terpenes,
flavonoids,glycosides
 Rasapanchaka-
Guna- Ruksha, Laghu
Rasa- Kashaya
Vipaka- Madhura
Virya- Ushna

 Properties
antioxidant properties, free radical scavenging
activities, beneficial for hair growth, antibacterial
activity

HARITAKI
 gjhrdh iF;kuke~
 Botanical name- Terminalia chebula
 Family- Combretaceae
 Part used- fruit
 Chemical constituents- chebulagic acid, chebulinic acid,
corilagin, amino acid.
 Rasapanchaka-
Guna- laghu, ruksha
Rasa- pancha rasa (lavana varjit), kashaya pradhana
Vipaka-madhura
Virya- ushna
Prabhava- tridosha hara

As rasayana
 Two haritaki fruits taken with jaggery, honey, sunthi, pippali
& salt (according to season) provides happiness & longevity.
(AH.U.39.147; also VM.69.3)
 Haritaki fried in ghee should be taken followed by intake of
ghee. It provides firm strength in the body. (AH.U.39.148)
Properties
antioxidant properties, free radical scavenging activities,
neuro protective

PIPPALI
jlk;uh
 Botanical name- Piper longum
 Family - Piperaceae
 Part used- fruit, root
 Rasapanchaka -
Guna- laghu, snigdha, tikshna
Rasa- katu
Vipaka- madhura
Virya- anushansheeta

 Chemical constituents
 In roots:
Piperine, piplartine, triacontane, dihydro-stigmasterol
glycosides
 In stems :
Two alkaloids piperlongumine and piperlonguminine
 Dried fruit :
piperine, piplartine, lignin d–sesamin, two piperdine
alkaloids

 Essential oil: Terpinolene, zingiberene, P- cymene, P-
methoxyacetophenone, two sesquiterpenes
 Piperine: It can turn a marginally effective substance into
a highly effective one by simply raising bioavailability
and intracellular residency time
Properties
Bioavailability enhancement, Hepato-protective activity,
anti-amoebic property

GAMBHARI
 Botanical name- Gmelina arborea
 Family- verbenaceae
 Part used- Mool, Phala, Patra Twaka
 Rasapanchaka
Guna- guru
Rasa- Kashaya, Tikta, Madhura
Vipaka- Katu
Virya- Ushna, (fruit- sheet)
Dosha karma – tridosha shamak

 Roots comprise yellow thick, oil, resin, an alkaloid and little
benzoic acid.
 Fruits consist of butyric acid and tartar acid, sugar and little
tannin.
 Leaves contain luteolin, which is an antioxidant classified
as a flavonoid

• Properties
• Helpful herb to improve digestion and
absorption in body.
• Good supporter for normal functioning of
heart.
• It is used in improving brain functioning
and it has feature to improve intelligence.
• Natural anti-aging agent.
• A natural strength enhancer of the body.
• It has properties of good aphrodisiac
(improve the quantity and quality of semen)
agent.

• One of the useful herb which has features
to increase milk secretion in the lactating
mother.
• Fruit of Gambhari is also efficient in
nourishing hair and promotes growth of
hair
• The fruits have advantageous anabolic
effects in tuberculosis to accelerate the
healing of cavitation in the lungs.

BALA
alkaloid (ephedrine, pseudoephedrine), flavanones,
phytosterols, malvalic acid
 Properties
aphrodisiac, rejuvenate urinary system, maintain
health of muscles

ERANDA
 ,j.Mewya o`";okrgjk.kke~ AA ¼p lw½
 Botanical name- Ricinus communis
 Family- Euphorbiaceae
 Part used- root, leaf, seed, oil
 Rasapanchaka-
Guna- snigdha, tikshna, sukshma
Rasa- madhura, anuras- katu, kashaya
Vipaka- madhura
Virya- ushna

 Chemical composition
 In root & root bark: Germanicol ester derivative , an
unidentified triterpene, inorganic material-K-
Na,Mg,Cl,No3,Fe,Al,Mn,Ca,Co3. & gallotanins.
 Oil: Chlorogenic, oleic, palmitic, ricinoleic, stearic,
dihydrostearic uric acids, hexadecanoic, hydrocyanic &
tocopheroles.
 Properties
aphrodisiac, effect on central nervous system (pericarp- in
mice), analgesic activity

BILWA
 Botanical name- Aegle marmelos
 Family- Rutaceae
 Part used- Mool, Phala, Patra, Twaka
 Chemical constituents- Marmelosin, Marmin,
Aegelinin, Aeglemarmelosine.
 Rasapanchaka
Guna- Laghu, Ruksha
Rasa- Kashaya, Tikta
Vipaka- Katu
Virya- Ushna

 Properties
 Leaf extract have phenolic and flavonoids contents,
β- carotene, glutathione, α- tocopherol, ascorbic
acid; due to which it shows good antioxidant
properties
 Recent researches also indicate that fruit pulp has
antioxidant properties

SHATAVARI
Active constituents
Steroidal saponins, oligospirostanoside
(~immunoside), flavonoids
Properties
Anti oxidant property increases larval G6PD activity
thus; extends life span (Drosophila study),
immunomodulator, immunoadjuvant, Galactagogue

ASHWAGANDHA
Active constituents
Various alkaloids, steroidal lactones, saponins
Properties
Withanamides (isolated from fruits) - effective in
protecting against beta- amyloid induced neurotoxicity
Antioxidant, adaptogenic, anxiolytic, anti-
inflammatory, anti- arthritic, hypolipidemic properties

WS root extract- neurotransmitter function
(catecholamines), acetylcholine regulation, serotonergic
effect( may be responsible for memory enhancing and
cognitive function)
ASHWAGANDHA

GOKSHURA
flavonoids, flavonol glycosides, steroidal saponins
and alkaloids.
 Properties
aphrodisiac, immunomodulator, absorption
enhancer, cardiotonic, central nervous system
protective, diuretic.

PUNARNAVA
iquuZok & jlk;us
 The name Punarnava itself means rejuvenation
Roots- rotenoids, flavonoids, punarnavoside (a
phenolic glycoside), C- methyl flavone, punarnavine
(alkaloids)
 Properties
adaptogenic, immuno modulator, antioxidant,
aphrodisiac and nootropic activities

Recent researches shows;
 strong antioxidant activity of extracts of B. diffusa
dried root powder
 In stressful conditions, it has demonstrated the
ability to buffer the elevations of serum cortisol and
prevent the suppression of the immune system
 Leaves revealed stronger antioxidant properties than
roots

AMLAVETAS
 Botanical name- Hyppophae rhamnoides (sea
buckthorn)
 Family- Elaeagnaceae
 Part used-Fruits
 Rasapanchaka-
Rasa- Amla
Guna- Laghu, Ruksha, Teekshna
Veerya- Ushna
Vipaka- Amla

Chemical constituents:
Rich source of vit. C
In Hippophae rhamnoides- polyphenoles
include flavonols, catechins, proanthocyanidins,
and chlorogenic acids, whereas the main fatty
acids of Hippophae rhamnoides are palmitoleic
acid, palmitic acid, linoleic acid, and oleic acid
Properties:
Berries show antioxidant activity
AMLAVETAS

List of drugs for Deerghayu in day to
day life
eqLrd fonkjh
vrlh fiIiyh
vtZqu nkyphuh
vkeydh rqylh
djenZ v’oxa/kk
e.Mwdi.khZ 'keh
esFkh f'kxzq
okjkgh ukfjdsy

SOME DEERGHAYUSHKARA FORMULATIONS
MENTIONED IN CLASSICS
 okjkfgdUn jlk;u ;ksx
 ’k.kQy jlk;u ;kssx
 fonkjhewy ;kssx
 e.Mwdi.khZ Lojl jlk;u
 Okpk jlk;u ;kssx
 ’krikd opk ?k`r
 es/kko/kZd opkfn ;kssx
 vk;qoZ/kZd jlk;u ;kssx
 Ckqf)es/kko/kZd x.k
 vk;qo/kZd x.k

TAKE HOME MESSAGE
 One who want to live a healthy, long life with
QUALITY, should follow the rules which are
mentioned in our classics
 Everyone should impart rasayan dravyas in the form
of ahara like green leafy vegetables and fruits, vihara
(Achara rasayana) and aushadha in day to day life to
embrace “Ayurvedamay jivan”

vk;qosZn% viuk;s
nh?kkZ;q% cus

Deerghayushkara rasayan drugs (2) pdf (1)

Deerghayushkara rasayan drugs (2) pdf (1)

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