Digital commerce is profoundly disrupting retail and represents significant growth opportunities. It now encompasses many merchants, platforms, and services beyond just Amazon and eBay. Digital commerce 2.0 is causing massive disruption, enabling permanent changes to consumer behavior, and taking an increasing share of spending. The online retail market in the US is forecast to grow from $155 billion to $249 billion from 2010 to 2014, representing over 8% of total retail sales. A variety of sectors like online retail, platforms, mobile, and infrastructure are innovating in digital commerce. Successful brands will be multichannel leaders across these sectors.