This document discusses three cranioplasty solutions from Biomet: HTR-PEKK, HTR-PMMA, and CranioCurve. HTR-PEKK is a laser sintered implant made of PEKK polymer that can be delivered in 8 days. HTR-PMMA is made of PMMA beads and PHEMA coating and allows for possible bone ingrowth. CranioCurve is a pre-contoured titanium mesh that is contourable and comes in multiple sizes and shapes.
⚕️ Su-Por®: Porous Polyethylene Sterile, Non-Pyrogenic & MR Safe ~ Craniomaxillofacial Implants for Reconstructive Surgery
⚕️ Why SU-POR?
~~~~~~~~~~~
✔️ SU-POR Surgical Implants are manufactured from a linear high-density polyethylene
✔️ Implants allow for tissue ingrowth because of the interconnecting open pore structure
✔️ The firm nature of the material allows carving with a sharp instrument without collapsing the pore structure
✔️ Surgical Implants are also intended for augmentation and restoration of contour in the craniomaxillofacial skeleton
✔️ The porosity of SU-POR Surgical Implants is maintained large, with average pore sizes greater than 100 microns and pore volume in the 50% range.
⚕️ SU-POR Surgical: Shapes
~~~~~~~~~~~~~~~~~~
✔️ Implants, available in blocks, sheets and preformed anatomical shapes are intended for non-weight bearing applications of craniofacial reconstruction/cosmetic surgery and repair of craniofacial trauma.
✔️ Select from an array of anatomical shapes, sheets, blocks, and spheres including:
o Preformed shapes for chin, malar, rim, midface and mandibular augmentation
o Reconstructive shapes for traumatic defects
o Sheets, wedges and blocks for orbital floor and wall repair
o Spheres and Conical Orbital Implants for enucleation and evisceration procedures
⚕️ Implants can be customized to accommodate the individual need of the patient.
⚕️ Su-Por®: Porous Polyethylene Sterile, Non-Pyrogenic & MR Safe ~ Craniomaxillofacial Implants for Reconstructive Surgery
⚕️ Why SU-POR?
~~~~~~~~~~~
✔️ SU-POR Surgical Implants are manufactured from a linear high-density polyethylene
✔️ Implants allow for tissue ingrowth because of the interconnecting open pore structure
✔️ The firm nature of the material allows carving with a sharp instrument without collapsing the pore structure
✔️ Surgical Implants are also intended for augmentation and restoration of contour in the craniomaxillofacial skeleton
✔️ The porosity of SU-POR Surgical Implants is maintained large, with average pore sizes greater than 100 microns and pore volume in the 50% range.
⚕️ SU-POR Surgical: Shapes
~~~~~~~~~~~~~~~~~~
✔️ Implants, available in blocks, sheets and preformed anatomical shapes are intended for non-weight bearing applications of craniofacial reconstruction/cosmetic surgery and repair of craniofacial trauma.
✔️ Select from an array of anatomical shapes, sheets, blocks, and spheres including:
o Preformed shapes for chin, malar, rim, midface and mandibular augmentation
o Reconstructive shapes for traumatic defects
o Sheets, wedges and blocks for orbital floor and wall repair
o Spheres and Conical Orbital Implants for enucleation and evisceration procedures
⚕️ Implants can be customized to accommodate the individual need of the patient.
EnvisionTEC 3D printers are known for accuracy, surface finish, reliability and speed. Our machines also deliver extreme flexibility with the power to print multiple materials.
Contact Engineering Technique – an all India distributors of EnvisionTEC 3D Printers. http://www.enggtechnique.com/3D-Printers
Dr. Guilherme Rocha, Dr. Paulo Ferrara, Dr. Leonardo Torquetti, Dra. Luciene Barbosa analisam os resultados dos implantes de Anel de Ferrara de Arco longo no pós operatório de 6 meses
OEMs and suppliers see promise in the ability of manufacturing and software to expand the use of custom implants in orthopaedics. Multiple companies are focused on the custom market. This session provides the surgeon perspective on these devices. What are the benefits? When should and shouldn't they be used? Will the market take off?
GORE® VIABIL® Short Wire Biliary Endoprosthesis - Product BrochureCONMED Corporation
The GORE® VIABIL® Short Wire Biliary Endoprosthesis is currently the only fully covered metal stent with anti-migration technology proven to minimize the risk of reintervention.
A multicentric nonrandomized study was conducted in which a new 320-ICRS was placed in 138 eyes of 130 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), keratometry, corneal volume, asphericity, lines of vision gain/loss, and vectorial analysis were assessed preoperatively and at the final follow-up visit after the procedure.
Inside you will find a large variety of Conical Connection & Internal Hex Connection products, compatible with leading systems in the market.
dibay™ - YOUR ONLINE IMPLANT SYSTEM
Hip Replacement Stem Cell Coating Business Plan-Hipsters R UsSagar Desai
A business plan for a startup focused on developing a stem cell coating to be used on hip replacement prosthetics. We outlined the technology to be used, regulations to be followed, and financials for the early development of the company. We also detailed the necessary quality requirements for a quality product.
Biotec dental implants are manufactured at our own state-of-the-art, in-house production facilities in Germany and comply with the highest standards. Our full Product Catalogue contains implants, prosthetics, CAD/CAM abutments as well as kits & tools. Download: http://biotec-implant.com
EnvisionTEC 3D printers are known for accuracy, surface finish, reliability and speed. Our machines also deliver extreme flexibility with the power to print multiple materials.
Contact Engineering Technique – an all India distributors of EnvisionTEC 3D Printers. http://www.enggtechnique.com/3D-Printers
Dr. Guilherme Rocha, Dr. Paulo Ferrara, Dr. Leonardo Torquetti, Dra. Luciene Barbosa analisam os resultados dos implantes de Anel de Ferrara de Arco longo no pós operatório de 6 meses
OEMs and suppliers see promise in the ability of manufacturing and software to expand the use of custom implants in orthopaedics. Multiple companies are focused on the custom market. This session provides the surgeon perspective on these devices. What are the benefits? When should and shouldn't they be used? Will the market take off?
GORE® VIABIL® Short Wire Biliary Endoprosthesis - Product BrochureCONMED Corporation
The GORE® VIABIL® Short Wire Biliary Endoprosthesis is currently the only fully covered metal stent with anti-migration technology proven to minimize the risk of reintervention.
A multicentric nonrandomized study was conducted in which a new 320-ICRS was placed in 138 eyes of 130 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), keratometry, corneal volume, asphericity, lines of vision gain/loss, and vectorial analysis were assessed preoperatively and at the final follow-up visit after the procedure.
Inside you will find a large variety of Conical Connection & Internal Hex Connection products, compatible with leading systems in the market.
dibay™ - YOUR ONLINE IMPLANT SYSTEM
Hip Replacement Stem Cell Coating Business Plan-Hipsters R UsSagar Desai
A business plan for a startup focused on developing a stem cell coating to be used on hip replacement prosthetics. We outlined the technology to be used, regulations to be followed, and financials for the early development of the company. We also detailed the necessary quality requirements for a quality product.
Biotec dental implants are manufactured at our own state-of-the-art, in-house production facilities in Germany and comply with the highest standards. Our full Product Catalogue contains implants, prosthetics, CAD/CAM abutments as well as kits & tools. Download: http://biotec-implant.com
With Piezomed, users can concentrate on the surgical procedure with a piece o...A-dec Australia
Piezomed from W&H facilitates the work of the oral surgeon with its innovative ultrasound technology. High-frequency microvibrations allow cutting with incredible precision and in addition, with the so called cavitation effect, you can also ensure an almost blood-free surgical site.
Bio3 Dental Implants Product 2018 Fresh and [Updated] AleksSokolov1
Making more smiles affordable for everyone and on any budget. Bio3 Implants is made in Germany and shipped to more than 60 countries.
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Visit CONMED at the AAOS 2017 Annual Meeting - Booth #2133 to see our new products and live in-booth presentations from Drs. Jeffrey Abrams, Myriam Capasso, Alex Castagna, James Cook, Gregory Fanelli, David Flanigan, Gonzalo Gomez and Joseph Tauro #AAOS2017
The Future of Personalized Implants in Joint Replacement: Additive, Robotics,...April Bright
Orthopedics is primed for mass customization of implants thanks to advancements in additive, AI and robotics. Fully leveraged, the technologies can produce patient-specific implants that achieve clinical benefit, decrease cost and maintain O.R. workflow. Founder and Chief Medical Officer of Monogram Orthopaedics, Douglas Unis, M.D., shares his reimagined vision of personalized joint replacement implants and just-in-time inventory solutions.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
3. Features
HTR-PEKK
Patient-Specific Anatomic Fit
Laser Sintered
PEKK Polymer
QuickTurnaround
Thickness Options
High Strength
Modification
Designed and manufactured based on uncompressed DICOM CT data
Laser sintered (3D printed) for precise, clean, and efficient manufacturing
Poly-Ether-Ketone-Ketone
Order for delivery in 8 business days
Unique design allows for flexibility of implant thickness and edge detail, highlighting our
patient-specific approach
High-strength, solid material with a compression strength of more than 34Kpsi1
May be modified by burring
1
OPM material Spec, on file. OsteoFab™ Medical Parts and Implants.
4. Features
HTR-PMMA
2
Eppley, Barry L., Michael Sadove, Hans Holmstrom, and Karl-Erik Kahnberg. HTR Polymer Facial Implants: A FiveYear Clinical Experience. Aesthetic Plastic Surgery (1995): 445-50.•3
Eppley, Barry L., Matthew Kilgo, and John J. Coleman.“Cranial Reconstruction with Computer Generated HardTissue Replacement Patient-Matched
Implants: Indications, SurgicalTechnique, and LongTerm Follow Up.”Plastic and Reconstructive Surgery (2001): 109.3: 864-71.
Patient-Specific Anatomic Fit
Copolymer Construction
Porous
Negative Surface Charge
Two Sterile Implants
Pre-Plated
Designed and manufactured based on uncompressed DICOM CT data
Polymethylmethacrylate (PMMA) beads and a Polyhydroxyethylmethacrylate (PHEMA) coating
Thickness Options
Unique design allows for flexibility of implant thickness and edge detail, highlighting our
patient-specific approach
Pore diameter ranges from 150-350 microns and supports possible connective tissue and
bone ingrowth3
May have minor positive effects on bony ingrowth and inhibition of bacterial adhesion3
Two gamma-sterilized implants are provided for each case
Pre-plating service is available which may help reduce operating room time
May be modified by burringModification
Hydrophilic
Allows placement of implant into antibiotic solution pre operatively; enables vascular flow
post operatively2
Cranio-Bro-d4.indd 5 5/26/15 12:25 PM
5. Anatomic shape
Features
CranioCurve™
Pre-Contoured
Titanium
Off the Shelf
Contourable
Variety
Anatomic shape to minimize the need for cutting
Pre-contoured to the general shape of an adult skull to minimize lengthy intraoperative bending
0.6mm Grade IITitanium for a balance of flexibility and strength
Allows for immediate cranioplasty in a variety of cranial regions
The 0.6mm mesh is contourable to allow for minor intraoperative adjustments
Use in conjunction with the Biomet 1.5mm Neuro Lorenz®
Plating System for easy integration
Left Parietal, Large - LPL
01-9523
Right Parietal, Small - RPS
01-9522
Left Parietal, Small - LPS
01-9521
Right Parietal, Large - RPL
01-9524
Occipital-OCC
01-9520
Compatibility
Multiple sizes and shapes for a variety of anatomic areas
6. To complement your cranioplasty procedures, please see our full portfolio of cranial closure products. To learn more about the broad range of Biomet
craniomaxillofacial solutions, please visit biometmicrofixation.com.
Mimix®
ThinFlap™
SterileTrac™
1.5 Neuro System RapidFlap® Spin Down
iQ™ Intelligent System