OpenStack Compute 101 provides an overview of OpenStack, focusing on its modules for infrastructure-as-a-service (IaaS) and the instance lifecycle management through the Nova component. Key topics include scheduling, compute drivers, resource segregation, and new features introduced in the Kilo release, such as API microversions for backward compatibility. The document emphasizes scaling compute services, understanding flavors and images, and the importance of logical groupings like regions, host aggregates, and availability zones.