This document provides guidance on effective communication and collaboration in eTwinning projects. It emphasizes that collaboration requires partners to contribute and rely on each other to complete activities. Synchronous tools like video conferencing and asynchronous tools like forums and blogs can facilitate communication. Setting guidelines, breaking the ice between partners, providing feedback, and engaging students in active collaborative tasks are keys to successful projects. Regular communication through Twinspace and live sessions helps build relationships and allows reflection. Integrating a variety of Web 2.0 tools maximizes interaction and participation.