1. CLINICAL FEATURES
&
COMPLICATION OF DENGUE FEVER
BY : ATIQAH BINTI SAPIYAN
BMD 104611
2. CLINICAL TAKEN PLACE FOR 3-7
FEATURES DAYS
FEVER : ≥ 38,50 C
FEBRILE
PHASE HEADACHE
VOMITING, MYALGIA AND
JOINT PAIN
Increasing hemoconcentration,
CLINICAL hypoprotein, pleural effusion,
FEATURES ascites
CRITICAL
PHASE
Skin bleeding, mucosal bleeding
(gastrointestinal or vaginal)
Moderate to severe
RECOVERY thrombocytopenia
PHASE
3. •Dengue fever
Acute febrile illnes with two or more of the following manifestation
Headache, Retro-orbital, Myalgia, Rash, Haemorrhagic
manifestation, leukopenia
•Dengue Haemorrhagic fever
•Fever
•Haemorrhagic tendencies
•Thrombocytopenia (100.000 cell per mm 3
•A rise in the haematocrit equal than 20%
•A drop in the haematocrit following volume replacement treatment equal to
or
•greater than 20% of baseline
•Sign of plasma leakage
4.
5. DF/DHF Grade Symptoms Laboratory
DF Fever with two or more of the leukopenia occasionally.
following sign : headache, retroorbital Thrombocytopenia, may be
pain, myalgia, arthralgia present,no evidence of plasma
loss
DHF I Above sign plus posisitve tourniquet Thrombocytopenia < 100.000,
test Hct rise ≥ 20%
DHF II Above sign plus spontaneous bleeding Thrombocytopenia < 100.000,
Hct rise ≥ 20%
DHF III Above sign plus circulatory failure Thrombocytopenia < 100.000,
(weak pulse, hypotension, restlessness) Hct rise ≥ 20%
DHF IV Profound shock with undetectable Thrombocytopenia < 100.000,
blood pressure and pulse Hct rise ≥ 20%
7. Central
encephalopat
nervous
hy
system
Liver failure
and renal
Intracranial
failure
bleeding
8. Leakage of plasma into serous
space
Abnormal hemostasis lead to
hypovolumic shock and
haemorrhage in body organ.
9. Leads to hepatomegaly
Liver damage manifests as increases in levels
of alanine aminotransferase and aspartate
aminotransferase, low albumin levels, and
deranged coagulation parameters
(prothrombin time, partial thromboplastin
time).
