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CHORDAL
PRESERVATION in
MITRAL VALVE
REPLACEMENT
BY
DR.VASANTHI
DNB-CARDIAC SURGERY
MADRAS MEDICAL MISSION
PLAN
 INTRODUCTION
 ANATOMY & PHYSIOLOGY
 HISTORICAL ASPECT
 EFFECTS OF CHORDAL PRESERVATION
 PHYSIOLOGICAL ALTERATION
 TECHNIQUES OF CHORDAL PRESRVATION
 RESULTS
 TAKE HOME MESSAGE
INTRODUCTION
 Aim of mitral valve surgery - to provide a competent, non-obstructed
valve without compromising the left ventricular (LV) function.
 Above aims are met with valve repair .
 When repair is not feasible- preservation of LV function is an
important concern.
 Awareness of deleterious effects of the loss of annulo-
ventricular continuity has increased, chordal preservation
has gained popularity
 Despite the clear advantages of complete chordal preservation ,many
surgeons still retain only the posterior leaflet
 greater technical complexity
 longer operating time
 fear of potential interference with mechanical leaflet motion
 need to undersize the mitral prosthesis possibility of LVOTO.
ANATOMY
ANNULO VENTRICULAR
CONTINUITY
 In 1922, Wiggers and Katz and later Rushmer et al proposed
the concept.
 left ventricular geometry and function -dynamic interaction
between the mitral annulus and the LV wall.
 The attachments between the mitral annulus and the LV wall
moderate the LV distension during diastole and wall tension
during systole.
 When the papillary muscles contract during the isometric
phase of the cardiac cycle,the closed MV is drawn into the LV
cavity thus reducing the longitudinal axis of the LV and
increasing its short axis.
 Diastolic recoil.
Effects of chordal transection
 Hansen -- transection of chordae to AML reduced the LV function
to a greater degree as compared to the transection of chordae to
PML.
 Chordal transection also appeared to shorten the long axis of the
LV with an increase in the short axis and dilatation of the
chamber.
 Transection of the chordae produced dyskinetic areas at the
insertion of severed papillary muscles
The parallel bars are the mitral annulus. (b) The arms of the gymnasts are
chordae and their bodies the papillary muscles. The floor is the left ventricular
wall.
Effect of chordal resection-Note dilatation & ventricular wall thickness where
chordae are resected partially or completely (a)Partial chordal resection (b)
Complete chordal resection.
Physiological changes
 Chronic MR- LV function gradually declines.
 Regurgitant stroke volume added to forward stroke
volume- increase EF in early phase.
 Progressive LV dilatation- increase Afterload.
 After MVR with chordal transection- EF determined by
contractility,preload ,afterload.
Historical aspect
 In 1964, Lillehei introduced the concept of
chordal preservation during MVR to reduce
the problem of post-operative low cardiac
output syndrome.
 David in 1981 reintroduced the concept- LV
function deteriorated if the chordae were
transected .
 Only those patients in whom the chordae
had been spared could increase the LV
ejection fraction (EF) and stroke volume
index.
 Also in the chordal preservation group, there
was better long-term systolic function and LV
performance both at rest and during exercise
TECHNIQUES
1.Preservation of posterior leaflet
1.PML Preservation-Lillehei
2.TOTAL CHORDAL
PRESERVATION
 With the development of low profile bi-leaflet mechanical
valves, and refinements in surgical technique, various
methods of total chordal preservation have been
described
 to preserve the LV systolic function
 to avoid interference with the mechanical prosthesis
function by portions of the retained subvalvular
apparatus
 to prevent left ventricular outflow tract obstruction
(LVOTO).
 In addition to these considerations, it is important to
adjust tension on the chordae during chordal
preservation as too much stress on the chordae can lead
to chordal rupture and entanglement with the prosthesis.
 Method of AML preservation should avoid the systolic
anterior motion of the AML which has the potential to
produce LVOTO.
3.DAVID’S TECHNIQUE
 Advantages :
 maintains the chordae in their natural anatomic
orientation
 reduced risk of LVOTO
 reduction in the bulk of leaflet tissue
 ADVANTAGES :
 specially useful while implanting tilting disc prosthesis where disc
entrapment is less
 Chordal continuity to the AML is well maintained.
 DISADVANTAGE :
 disturbs the normal geometric relationships of the mitral subvalvular
apparatus
 which could alter the distribution of regional LV wall stresses and disturb
chordal tension during papillary muscle contraction thereby reducing
global LV systolic and diastolic function
 Khonsari I technique -After the AML is detached from the annulus
between the two commissures, an ellipse of tissue is excised and
the rim of the leaflet tissue containing the chordae is reattached to
the anterior annulus
 Khonsari II technique-If the leaflet is thick or calcified, it is divided
into 2-5 chordal segments which are re-attached to the annulus
 ADVANTAGE :
 no reported incidence of LVOTO or interference with
prosthetic valve function.
 It is believed that myocardial rupture is prevented by
maintaining the tethering effect of the intact subvalvular
apparatus.
 CONCERN :
 chordae could become stretched around the struts of
the bioprostheses thereby exerting more stress on the
retained chordae
 Advantages :
 reduced bulk of the AML which reduces the
possibility of impairment of valve function
 low risk of LVOTO,
 reduced risk of thrombosis on the redundant
leaflet tissue.
MIKI’s TECHNIQUE
Advantage
 Simple, and LVOTO is uncommon with good preservation of LV
function
 Suitable for patients with RHD and thickened, and calcific cusps
 Allows placement of a larger prosthesis.
 Use of a low profile prosthesis further reduces the incidence of
leaflet obstruction from retained chordae.
Vander-Salm andYu
technique
ADVANTAGE:
 If the AML is large, it is reefed within the sutures and
the prosthetic valve is seated and tied.
 The native leaflet is reefed and compressed
between the prosthesis and the native annulus and
also chordal tension is evenly maintained
Safeguards-Ideal method
 The factors to be considered are the
 Simplicity
 reproducibility of the technique
 prevention of post-operative LVOTO due to systolic
anterior motion of the remaining AML risk of interference
with the prosthetic valve function.
 The technique used should allow for implantation of an
adequate size prosthesis to prevent post-operative
patient-prosthesis mismatch..
TAKE HOME MESSAGE
 Complete chordal preservation advantages.
 It preserves LV geometry and function
 reduces the operative mortality
 improves early and long-term survival
reduces the risk of ventricular rupture.
 With appropriate surgical technique even large
size prosthetic valves can be implanted and the
risk of prosthetic valve dysfunction and LV outflow
tract obstruction can be eliminated.
 There is emerging evidence which suggests that
RV function may improve significantly after LV
chordal preservation.
Chordal preservation in  mitral valve replacement

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Chordal preservation in mitral valve replacement

  • 2. PLAN  INTRODUCTION  ANATOMY & PHYSIOLOGY  HISTORICAL ASPECT  EFFECTS OF CHORDAL PRESERVATION  PHYSIOLOGICAL ALTERATION  TECHNIQUES OF CHORDAL PRESRVATION  RESULTS  TAKE HOME MESSAGE
  • 3. INTRODUCTION  Aim of mitral valve surgery - to provide a competent, non-obstructed valve without compromising the left ventricular (LV) function.  Above aims are met with valve repair .
  • 4.  When repair is not feasible- preservation of LV function is an important concern.  Awareness of deleterious effects of the loss of annulo- ventricular continuity has increased, chordal preservation has gained popularity
  • 5.  Despite the clear advantages of complete chordal preservation ,many surgeons still retain only the posterior leaflet  greater technical complexity  longer operating time  fear of potential interference with mechanical leaflet motion  need to undersize the mitral prosthesis possibility of LVOTO.
  • 7.
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  • 9. ANNULO VENTRICULAR CONTINUITY  In 1922, Wiggers and Katz and later Rushmer et al proposed the concept.  left ventricular geometry and function -dynamic interaction between the mitral annulus and the LV wall.  The attachments between the mitral annulus and the LV wall moderate the LV distension during diastole and wall tension during systole.  When the papillary muscles contract during the isometric phase of the cardiac cycle,the closed MV is drawn into the LV cavity thus reducing the longitudinal axis of the LV and increasing its short axis.  Diastolic recoil.
  • 10.
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  • 12.
  • 13. Effects of chordal transection  Hansen -- transection of chordae to AML reduced the LV function to a greater degree as compared to the transection of chordae to PML.  Chordal transection also appeared to shorten the long axis of the LV with an increase in the short axis and dilatation of the chamber.  Transection of the chordae produced dyskinetic areas at the insertion of severed papillary muscles
  • 14. The parallel bars are the mitral annulus. (b) The arms of the gymnasts are chordae and their bodies the papillary muscles. The floor is the left ventricular wall.
  • 15. Effect of chordal resection-Note dilatation & ventricular wall thickness where chordae are resected partially or completely (a)Partial chordal resection (b) Complete chordal resection.
  • 16. Physiological changes  Chronic MR- LV function gradually declines.  Regurgitant stroke volume added to forward stroke volume- increase EF in early phase.  Progressive LV dilatation- increase Afterload.  After MVR with chordal transection- EF determined by contractility,preload ,afterload.
  • 17. Historical aspect  In 1964, Lillehei introduced the concept of chordal preservation during MVR to reduce the problem of post-operative low cardiac output syndrome.  David in 1981 reintroduced the concept- LV function deteriorated if the chordae were transected .
  • 18.  Only those patients in whom the chordae had been spared could increase the LV ejection fraction (EF) and stroke volume index.  Also in the chordal preservation group, there was better long-term systolic function and LV performance both at rest and during exercise
  • 21. 2.TOTAL CHORDAL PRESERVATION  With the development of low profile bi-leaflet mechanical valves, and refinements in surgical technique, various methods of total chordal preservation have been described  to preserve the LV systolic function  to avoid interference with the mechanical prosthesis function by portions of the retained subvalvular apparatus  to prevent left ventricular outflow tract obstruction (LVOTO).
  • 22.  In addition to these considerations, it is important to adjust tension on the chordae during chordal preservation as too much stress on the chordae can lead to chordal rupture and entanglement with the prosthesis.  Method of AML preservation should avoid the systolic anterior motion of the AML which has the potential to produce LVOTO.
  • 24.
  • 25.
  • 26.  Advantages :  maintains the chordae in their natural anatomic orientation  reduced risk of LVOTO  reduction in the bulk of leaflet tissue
  • 27.
  • 28.
  • 29.  ADVANTAGES :  specially useful while implanting tilting disc prosthesis where disc entrapment is less  Chordal continuity to the AML is well maintained.  DISADVANTAGE :  disturbs the normal geometric relationships of the mitral subvalvular apparatus  which could alter the distribution of regional LV wall stresses and disturb chordal tension during papillary muscle contraction thereby reducing global LV systolic and diastolic function
  • 30.
  • 31.
  • 32.
  • 33.  Khonsari I technique -After the AML is detached from the annulus between the two commissures, an ellipse of tissue is excised and the rim of the leaflet tissue containing the chordae is reattached to the anterior annulus  Khonsari II technique-If the leaflet is thick or calcified, it is divided into 2-5 chordal segments which are re-attached to the annulus
  • 34.  ADVANTAGE :  no reported incidence of LVOTO or interference with prosthetic valve function.  It is believed that myocardial rupture is prevented by maintaining the tethering effect of the intact subvalvular apparatus.  CONCERN :  chordae could become stretched around the struts of the bioprostheses thereby exerting more stress on the retained chordae
  • 35.
  • 36.
  • 37.
  • 38.  Advantages :  reduced bulk of the AML which reduces the possibility of impairment of valve function  low risk of LVOTO,  reduced risk of thrombosis on the redundant leaflet tissue.
  • 40.
  • 41. Advantage  Simple, and LVOTO is uncommon with good preservation of LV function  Suitable for patients with RHD and thickened, and calcific cusps  Allows placement of a larger prosthesis.  Use of a low profile prosthesis further reduces the incidence of leaflet obstruction from retained chordae.
  • 42.
  • 44.
  • 45.
  • 46. ADVANTAGE:  If the AML is large, it is reefed within the sutures and the prosthetic valve is seated and tied.  The native leaflet is reefed and compressed between the prosthesis and the native annulus and also chordal tension is evenly maintained
  • 47.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56. Safeguards-Ideal method  The factors to be considered are the  Simplicity  reproducibility of the technique  prevention of post-operative LVOTO due to systolic anterior motion of the remaining AML risk of interference with the prosthetic valve function.  The technique used should allow for implantation of an adequate size prosthesis to prevent post-operative patient-prosthesis mismatch..
  • 57. TAKE HOME MESSAGE  Complete chordal preservation advantages.  It preserves LV geometry and function  reduces the operative mortality  improves early and long-term survival reduces the risk of ventricular rupture.
  • 58.  With appropriate surgical technique even large size prosthetic valves can be implanted and the risk of prosthetic valve dysfunction and LV outflow tract obstruction can be eliminated.  There is emerging evidence which suggests that RV function may improve significantly after LV chordal preservation.