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Test of significance-The Chi-Square
Dr. O. E. Adegbilero-Iwari
College of Medicine & Health Sciences,
Afe-Babalola University Ado-Ekiti, Ekiti, Nigeria.
1
CONTINGENCY TABLE
The classification, according to two criteria, of a set of
entities, say, people, can be shown by a table in which
the r rows represent the various levels of one criterion
of classification and the c columns represent the
various levels of the second criterion. Such a table is
generally called a contingency table, with dimension
r x c.
A 3x 2 CONTINGENCY TABLE
Weight Status
Smoking
Yes No
Underweight 17 97
Overweight 25 142
Appropriate 96 816
Chi-Square
It is the most frequently employed statistical
technique in the analysis of count or
frequency data.
It is also the most widely used distribution in
statistical applications
Uses of Chi-square
• Test of dependence
• Test of Homogeneity
• Goodness of fit
EXAMPLE
In 1992, the U.S. Public Health Service and the Centers for
Disease Control and Prevention recommended that all women
of childbearing age consume 400mg of folic acid daily to reduce
the risk of having a pregnancy that is affected by a neural tube
defect such as spina-bifida or anencephaly. In a study by
Stepanuk et al, 636 pregnant women called a teratology
information service about their use of folic acid
supplementation. The researchers wished to determine if
preconception use of folic acid and Race are dependent.
Preconceptional use of folic acid
YES NO TOTAL
White 260 299 559
Black 15 41 56
Other 7 14 21
total 282 354 636
Steps for testing the Hypothesis
i. Test of Hypotheses
• Null hypothesis (𝐻𝑂)
• Alternative hypothesis (𝐻1)
ii. Significance level
iii. Test statistic
iv. Critical value
v. Decision rule and Decision
vi. Conclusion
TEST OF HYPOTHESES
𝐻0 : There is no association between Race and
preconceptional use of folic acid (The
variables are independent)
𝐻1 : There is an association between Race and
Preconceptional use of folic acid (The
variables are dependent)
SIGNIFICANCE LEVEL
𝛼 = 0.05
TEST STATISTIC
When 𝐻0 is true,
𝑋2
is distributed ~ 𝜒2
(𝑟−1)(𝑐−1)
CRITICAL VALUE
This Is obtained from the chi-square table
𝜒2
[ 𝑟−1 𝑐−1 , 𝛼] , r = 3, c = 2
= 𝜒2
[2, 0.05] = 𝜒2
[2, 1−0.05 𝑖𝑛 𝑝𝑒𝑟𝑐𝑒𝑛𝑡𝑖𝑙𝑒]
TEST STATISTIC
𝑿𝟐
= 𝒊=𝟏
𝒌
[
(𝑶𝒊−𝑬𝒊)𝟐
𝑬𝒊
] -------------- equation (1)
CALCULATION OF TEST STATISTICS
We need to obtain the expected frequencies and
then substitute them back into equation (1) above
In general, to obtain the expected
frequency of a given cell, we multiply the
total of the row in which the cell is
located by the total of the column in
which the cell is located and divide by
the grand total.
𝑬𝟏𝟏 𝑬𝟏𝟐
𝑬𝟐𝟏 𝑬𝟐𝟐
𝑬𝟑𝟏 𝑬𝟑𝟐
YES NO Row total
White 260 299 559
Black 15 41 56
Other 7 14 21
Column total 282 354 636
𝑬𝑖𝑗 =
𝑅𝑖𝑗 × 𝐶𝑖𝑗
𝐺
𝑬𝟏𝟏 =
𝟓𝟓𝟗×𝟐𝟖𝟐
𝟔𝟑𝟔
= 247.86 𝑬𝟏𝟐 =
𝟓𝟓𝟗×𝟑𝟓𝟒
𝟔𝟑𝟔
= 311.14
𝑬𝟐𝟏 =
𝟓𝟔×𝟐𝟖𝟐
𝟔𝟑𝟔
= 24.83 𝑬𝟐𝟐 =
𝟓𝟔×𝟑𝟓𝟒
𝟔𝟑𝟔
= 31.17
𝑬𝟑𝟏 =
𝟐𝟏×𝟐𝟖𝟐
𝟔𝟑𝟔
= 9.31 𝑬𝟑𝟐 =
𝟐𝟏×𝟑𝟓𝟒
𝟔𝟑𝟔
= 11.69
𝑬𝟏𝟏 = 247.86 𝑬𝟏𝟐 = 311.14
𝑬𝟐𝟏 = 24.83 𝑬𝟐𝟐 = 31.17
𝑬𝟑𝟏 = 9.31 𝑬𝟑𝟐 = 11.69
YES NO
WHITE 260 (247.86) 299 (311.14)
BLACK 15 (24.83) 41 (31.17)
OTHER 7 (9.31) 14 (11.69)
𝑿𝟐
= 𝒊=𝟏
𝒌
[
(𝑶𝒊−𝑬𝒊)𝟐
𝑬𝒊
]
=
(260−247.86)2
247.86
+
(299−311.14)2
311.14
+
(15−24.83)2
24.83
+
(41−31.17)2
31.17
+
(7−9.31)2
9.31
+
(14−11.69)2
11.69
𝑋2
= 9.08960
DECISION RULE
Reject the null hypothesis (𝐻0 ) if calculated
test statistic (𝑋2
) is greater than tabulated
value otherwise do not reject.
DECISION
We reject 𝐻0 since 9.0896 (𝑋2
) is greater
than tabulated 𝜒2
value of 5.991
CONCLUSION
We conclude that there exist an association
between the preconception use of folic acid and
race which implies that the two variables are
dependent.
Exercise
Some researchers examined the beliefs held by adolescents regarding smoking and
weight. Respondents characterized their weight into three categories: underweight,
overweight or appropriate. Smoking status was categorized according to the answer to
the question, “Do you currently smoke, meaning one or more cigarettes per day?”
The following table shows the results of a telephone study of adolescents in the age
group 12-17. Does the data provide sufficient evidence to suggest that weight
perception and smoking status are related in adolescents? Take 𝛼 = 0.05
Smoking
Weight perception Yes No
Underweight 17 97
Overweight 25 142
Appropriate 96 816
Chi-square msc.pptx

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Chi-square msc.pptx

  • 1. Test of significance-The Chi-Square Dr. O. E. Adegbilero-Iwari College of Medicine & Health Sciences, Afe-Babalola University Ado-Ekiti, Ekiti, Nigeria. 1
  • 2. CONTINGENCY TABLE The classification, according to two criteria, of a set of entities, say, people, can be shown by a table in which the r rows represent the various levels of one criterion of classification and the c columns represent the various levels of the second criterion. Such a table is generally called a contingency table, with dimension r x c.
  • 3. A 3x 2 CONTINGENCY TABLE Weight Status Smoking Yes No Underweight 17 97 Overweight 25 142 Appropriate 96 816
  • 4. Chi-Square It is the most frequently employed statistical technique in the analysis of count or frequency data. It is also the most widely used distribution in statistical applications
  • 5. Uses of Chi-square • Test of dependence • Test of Homogeneity • Goodness of fit
  • 6. EXAMPLE In 1992, the U.S. Public Health Service and the Centers for Disease Control and Prevention recommended that all women of childbearing age consume 400mg of folic acid daily to reduce the risk of having a pregnancy that is affected by a neural tube defect such as spina-bifida or anencephaly. In a study by Stepanuk et al, 636 pregnant women called a teratology information service about their use of folic acid supplementation. The researchers wished to determine if preconception use of folic acid and Race are dependent.
  • 7. Preconceptional use of folic acid YES NO TOTAL White 260 299 559 Black 15 41 56 Other 7 14 21 total 282 354 636
  • 8. Steps for testing the Hypothesis i. Test of Hypotheses • Null hypothesis (𝐻𝑂) • Alternative hypothesis (𝐻1) ii. Significance level iii. Test statistic iv. Critical value v. Decision rule and Decision vi. Conclusion
  • 9. TEST OF HYPOTHESES 𝐻0 : There is no association between Race and preconceptional use of folic acid (The variables are independent) 𝐻1 : There is an association between Race and Preconceptional use of folic acid (The variables are dependent) SIGNIFICANCE LEVEL 𝛼 = 0.05
  • 10. TEST STATISTIC When 𝐻0 is true, 𝑋2 is distributed ~ 𝜒2 (𝑟−1)(𝑐−1) CRITICAL VALUE This Is obtained from the chi-square table 𝜒2 [ 𝑟−1 𝑐−1 , 𝛼] , r = 3, c = 2 = 𝜒2 [2, 0.05] = 𝜒2 [2, 1−0.05 𝑖𝑛 𝑝𝑒𝑟𝑐𝑒𝑛𝑡𝑖𝑙𝑒]
  • 11.
  • 12. TEST STATISTIC 𝑿𝟐 = 𝒊=𝟏 𝒌 [ (𝑶𝒊−𝑬𝒊)𝟐 𝑬𝒊 ] -------------- equation (1) CALCULATION OF TEST STATISTICS We need to obtain the expected frequencies and then substitute them back into equation (1) above
  • 13. In general, to obtain the expected frequency of a given cell, we multiply the total of the row in which the cell is located by the total of the column in which the cell is located and divide by the grand total.
  • 15. YES NO Row total White 260 299 559 Black 15 41 56 Other 7 14 21 Column total 282 354 636 𝑬𝑖𝑗 = 𝑅𝑖𝑗 × 𝐶𝑖𝑗 𝐺
  • 16. 𝑬𝟏𝟏 = 𝟓𝟓𝟗×𝟐𝟖𝟐 𝟔𝟑𝟔 = 247.86 𝑬𝟏𝟐 = 𝟓𝟓𝟗×𝟑𝟓𝟒 𝟔𝟑𝟔 = 311.14 𝑬𝟐𝟏 = 𝟓𝟔×𝟐𝟖𝟐 𝟔𝟑𝟔 = 24.83 𝑬𝟐𝟐 = 𝟓𝟔×𝟑𝟓𝟒 𝟔𝟑𝟔 = 31.17 𝑬𝟑𝟏 = 𝟐𝟏×𝟐𝟖𝟐 𝟔𝟑𝟔 = 9.31 𝑬𝟑𝟐 = 𝟐𝟏×𝟑𝟓𝟒 𝟔𝟑𝟔 = 11.69
  • 17. 𝑬𝟏𝟏 = 247.86 𝑬𝟏𝟐 = 311.14 𝑬𝟐𝟏 = 24.83 𝑬𝟐𝟐 = 31.17 𝑬𝟑𝟏 = 9.31 𝑬𝟑𝟐 = 11.69 YES NO WHITE 260 (247.86) 299 (311.14) BLACK 15 (24.83) 41 (31.17) OTHER 7 (9.31) 14 (11.69)
  • 19. DECISION RULE Reject the null hypothesis (𝐻0 ) if calculated test statistic (𝑋2 ) is greater than tabulated value otherwise do not reject. DECISION We reject 𝐻0 since 9.0896 (𝑋2 ) is greater than tabulated 𝜒2 value of 5.991
  • 20. CONCLUSION We conclude that there exist an association between the preconception use of folic acid and race which implies that the two variables are dependent.
  • 21. Exercise Some researchers examined the beliefs held by adolescents regarding smoking and weight. Respondents characterized their weight into three categories: underweight, overweight or appropriate. Smoking status was categorized according to the answer to the question, “Do you currently smoke, meaning one or more cigarettes per day?” The following table shows the results of a telephone study of adolescents in the age group 12-17. Does the data provide sufficient evidence to suggest that weight perception and smoking status are related in adolescents? Take 𝛼 = 0.05 Smoking Weight perception Yes No Underweight 17 97 Overweight 25 142 Appropriate 96 816