Chapter 2 - hematology.pdf

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Chapter 2
Hematology
(200 question)

1) CO2 transported in Plasma as
a. Bicarbonate ions (HCO3)
b. Carbonate ions
c. Carbohydrate
d. CO2.
2) Diseases associated with inherited hemolytic anemia
a. Sickle cell diseases.
b. Thalassemia.
c. G6PD.
d. ALL.
3) In Disseminated Intravascular Coagulation (DIC) diagnosis by
a. PT
b. PTT
c. Reduced in fibrinogens level
d. Severe Thrombocytopenia *reduced Platelets*
e. ALL

4) B- Cell produce.
a. Antibodies
b. Cytokines
c. Sugar
d. Toxic
5) DAT positive test occurs in Cases such as
a. Hemolytic disease of newborn
b. Hemolytic Blood transfusion
c. Warm reactive autoantibodies
d. All.
6) Leukocytes have short life Spain polymorph nuclear
multiple lopes and have mobile phagocytosis have
receptor for IgG and complement.
a. Basophiles
b. Monocyte
c. Lymphocytes
d. Neutrophils

7) Leukocytes involved in anaphylactic hypersensitivity and inflammatory
reaction
a. Basophiles
b. monocytes
c. Lymphocytes
d. Eosinophil.
8) Fixed tissue macrophages are
a. Monocytes
b. Lymphocytes
c. Neutrophils
d. Eosinophils.
9) A guideline reference range for MCV in health patient
a. 80 - 98fl
b. 27 - 32 pg
c. 31.5 -36 g/dl.
d. 15 -18 mg/dl.

10) Guideline reference range for MCH in health patient
a. 80 - 98fl
b. 27 - 32 pg
c. 31.5 -36 g/dl.
d. 15 -18 mg/dl.
11) A guideline reference range for MCHC in health patient
a. 80 - 98fl
b. 27 - 32 pg
c. 31.5 -36 mg/dl.
d. 15 -18 g/dl.
12) Anticoagulant used in W.B. Cs counting
a. Sodium citrate
b. SPS
c. EDITA
d. Heparin.

13) In manual counting of platelets the solution used is
a. Acetic acid
b. Normal saline
c. Ammonium oxalate reagent
d. Non
14) One of the following test cannot perform using capillary blood
a. Hemoglobin
b. Platelets
c. WBCs
d. RBCs
15) Neutrophils count in normal patient.
a. 21- 40 %
b. 1-6%
c. 0 -1 %.

16) Anticoagulant used in ESR test
a. Sodium citrate
b. Ammonium oxalate
c. EDITA
d. Heparin
17) Raised reticulocyte counts found when there is
a. Hemolytic anemia
b. Diabetius mellitus
c. Pancretic disease
d. Stomach ulcer
18) The main HB in infant below 3 months.
a. HBA
b. HBA2
c. HBF
d. HBS

19) Anticoagulant used in prothrombin time-assays-
a. Sodium citrate
b. Ammonium oxalate
c. SPS
d. EDITA
20) The person should not have donated blood within the
previous
a. 3 months.
b. 5month.
c. 2 months.
d. 1 year.
21) Blood grouping antibodies are
a. IgG
b. IgM
c. IgE
d. IgD

22) Antibodies associated in Rh.
a. IgG
b. IgM
c. IgE
d. IgD
23) The nature of Antibodies
a. Glycoprotein
b. Polysaccharide
c. Lipids
d. Cardiolipin

24) Immunoglobin consists of five parts of Antibodies (Pentamoric).
a. IgG
b. IgM
c. IgD
d. IgA
25) Heparin tube color
a. Red
b. Blue
c. Green
d. Yellow
26) A good complement fixing antibodies
a. IgG
b. IgM
c. IgD
d. IgE

27) Normal plasma clot APTT
a. 26- 40 Sec.
b. 1-16 Sec.
c. 12- 15 Sec.
d. 4 min
28) Normal plasma Prothrombin time (PT)
a. 36-50 Sec.
b. 15-20 Sec.
c. 12-16 Sec.
d. 4 min

29) Normal plasma clot Thrombin time (TT).
a. 36-50 Sec.
b. 11-16 Sec.
c. 12-15 Sec.
d. 1-4 min
30) EDITA tube color
a. Red
b. Blue
c. Green
d. Lavender
31) Sodium citrate tube color
a. Red
b. Blue
c. Green
d. Yellow

32) A person with A blood group can receive blood from:
a. A blood group donor.
b. B blood group donor.
c. Blood group donor.
d. A and C
33) Philadelphia chromosome is a specific chromosomal abnormality that is
associated with.
a. ALL
b. AML
c. CML
d. None.

34) Life Spain of platelets in bags stored at R.T.
a. 35 day
b. 41 day
c. 3 months
d. 5 day.
35) Cells not contain nucleus.
a. Erythrocyte
b. Leukocyte
c. Platelets
d. blast cell
36) T. cell maturation in
a. Bone marrow
b. Thymus
c. Spleen
d. Liver

37) Which of the following immunoglobulins is present normally in plasma at the
highest concentration?
a. IgG
b. IgM
c. IgA
d. IgD
38) Which immunoglobulin is the principal one found in secretions
such as milk?
a. IgG
b. IgM
c. IgA
d. LgE

39) Normal reticulocyte in adult is
a. 0.2-0.5 %
b. 2-5 %
c. 0.2-2 %
d. I-2 %
40) Deficiency in folate & vitamin B12 cause
a. Megaloblastic Anemia
b. Liver cirrhosis
c. Kidney failure
d. Kala azar
41) Which of the following immunoglubin have four molecules?
a. IgG
b. IgE
c. IgA
d. IgM S

42) Which of the following can't donate blood
a. Person have Hb>13 mg/dl
b. Woman is pregnant
c. Person free from syphilis
d. ALL
43) Which of the following transmitted through blood transfusion
a. Malaria
b. Aids
c. Cytomegalovirus (CMV)
d. All of the above

44) Red blood cell synthesis in bone marrow from
a. Fate cell
b. Cord cell
c. Myeloid cell
d. Stem cells s
45) Leukemia characterized by a greatly increased in leukocyte
count
a. ALL
b. AML
c. CML
d. None.

46) Platelets synthesis in bone marrow from
a. Fate cell
b. Cord cell
c. Myeloid cell
d. Megakaiyocyte
47) Granulocytic leukemia
a. ALL
b. AML
c. CML
d. None.
48) The Lowest rang of platelets'
a. 450 x 103
b. 100 x 103
c. 250 x 103
d. 500 x 103

49) Factor II of blood clotting is:
a. Christmas factor
b. Fibrinogen
c. Prothrombin
d. Thromboplastin
50) Factor I of blood clotting is:
a. Christmas factor
b. Fibrinogen
c. Prothrombin
d. Thromboplastin

51) One of the intrinsic pathways
a. Factor XI
b. Factor XIII
c. Factor I
d. Factor VII
52) Factors present only in Extrinsic Pathway.
a. Factor XI
b. Factor XIII
c. Factor I
d. Factor VII
53) Test for Intrinsic pathway:
a. Bleeding time
b. Thrombin time
c. Prothrombin time
d. Partial thromboplastin time PTT

54) Infectious mononucleosis is caused by:
a. Echo virus
b. Coxsaki virus
c. Epstein Barr virus EBV
d. Cytomegalo virus
55) Malaria diagnosis by
a. Thick blood film
b. Thin blood film
c. Skin scraping
d. X-ray

56) In ABO the Rh container color?
a. Yellow
b. Blue
c. Red
d. Colorless
57) MCV measuring Unit
a. FL (Fimtolitre)
b. Pg (Picogram)
c. g/1
d. Mg/di.
58) MCH measuring Unit
a. FL (Fimtolitre)
b. Pg (Picogram)
c. g/1
d. mg/d1.
59) MCHC measuring Unit
a. FL (Fimtolitre)
b. Pg (Picogram)
c. g/I

d. mg/d1.
60) More abundant leukocyte
a. Basophile
b. Monocyte
c. Lymphocyte
d. Neutrophils

61) One test in the following can diagnose anemia :
a. CBC
b. PT
c. PTT
d. Platelets
62) The following test do in chemical lab except
a. CBC
b. Creatinine
c. SGPT
d. Uric acid
63) If blood clot occur that is called.
a. Hemolysis
b. Blood coagulation
c. Thrombosis
d. Purification

64) Substance cannot trans and absorbed without a factor
a. Iron
b. Vitamin B12
c. Folic acid
d. Vitamin A
65) The main site of production of ATP in the cell is
a. Cell wall
b. Cell membrane
c. Cytoplasm
d. Mitochondria

66) Number of bonds in Antibodies
a. 2
b. 3
c. 4
d. 5
67) Antibodies contain four IG
a. Ig M
b. Ig A
c. Ig D
d. IgG

68) Which one of the following is not an anticoagulant?
a. Heparin
b. Citrate
c. Phosphate
d. EDITA
69) Prolonged bleeding time commonly occurs in
a. Damage to vascular endothelium
b. Disorder of platelets
c. Disorder of blood coagulation
d. ALL
70) Prolonged bleeding time commonly occurs in
a. Defect PTT
b. Reduction Platelets number
c. Reduction W.BC.
d. ALL

71) Permanent deferral of a donor occurs in
a. Hepatitis
b. AIDS
c. A and B
d. Mumps
e. Rubella
72) A pheresis is the collection of
a. CSF
b. Bone marrow aspiration
c. Blood component
d. 24 h. urine

73) The total leukocytes count less than normal range
a. Typhoid infection
b. Leukopenia
c. S.Pyogenes
d. A and B
74) Primary homeostasis
a. Platelets adhesion (Plug)
b. RBCs destruction
c. W.B.Cs formation
d. Prothrombin time

75) Glucose-6-phosphate enzymes are present in
a. W.B.Cs
b. Erythrocyte
c. Plasma
d. Platelets
76) Blood collected on plain tube (without anticoagulant) must
a. Be incubate at 37c for 30 min
b. Not be clotte
c. Be hemolysed
d. Be mixed

77) The all ABO group true except:
a. AB group transfusion only to person AB
b. A group transfusion to group A and O group
c. O group can transfusion into person have A and B and 0 group
d. O group the contain both Antigen A and B
78) All component of blood except:
a. Platelet
b. Red cells and white
c. Plasma
d. Cell wall
79) Can transfusion from blood:
a. Whole blood
b. Platelets
c. Red cells

d. All the abov
80) The general Trans O group to:
a. A group
b. B group
c. O group
d. ALL groups
81) Thrombocytopenia sees in:
a. Megaloplastic anemia
b. A plastic anemia
c. Iron deficiency
d. Pernicious anemia

82) ESR measured
a. Millimeters
b. Centimeter
c. Milligram
d. Dl.
83) Strong antigen:
a. Vitamin
b. Carbohydrate
c. Proteins
d. Saccharide
84) ANA is (Antinuclear antibody):
a. Allergy
b. Sideroblastic anemia
c. Graft-rejection
d. Autoimmune disease

85) Normocytic Normochromic anemia found in
a. Pernicious anemia
b. Megaloplastic anemia
c. a plastic anemia
d. Iron. Deficiency
86) Neonatal jaundice is
a. Hemolytic jaundice
b. Obstructive jaundice
c. Hepatic jaundice
d. Physiological jaundice
87) The blood cells that play a major role in preventing
infection of the body are
a. Erythrocyte
b. Leukocyte
c. Platelets
d. Blast Cells

88) The dimeric Antibodies is
a. IgG
b. IgM
c. IgE
d. IgA
89) Which of the following of immunoglobulin inflexible:
a. IgG
b. Ig M
c. Ig A
d. Ig E

90) One test in the following can diagnose iron deficiency:
a. CBC
b. Cretinin
c. sGPT
d. Uric acid
91) The maximum store of the platelet is
a. 35 days
b. 7 days
c. 5 days
d. 120 days

92) In agglutination test the antigen used is:
a. Soluble
b. Insoluble
c. All of the above
d. Non of the above
93) Which of the following tubes used in
serology tests :
a. Plan tube
b. EDTA tube
c. Heparin tube
d. Lavender tube

94) Hormone replication of RBCs:
a. Erythropoietin
b. Creatin kinas
c. Amylase
d. Progesterone
95) Variation in RBCs size:
a. Microcyrosis-
b. Macrocytosis
c. Anisocytosis
d. Poikiocytosis

96) All the following estimation can be done on plasma EDTA blood
except:
a. Glucose
b. Urea
c. Calcium
d. HIV test
97) Lenses near the slide in light microscope:
a. Objective
b. Stage
c. Eye lenses
d. Arms

98) Storage temperature of platelets
a. 37 C
b. 35 — 40
c. 22 — 27
d. 4
99) It's function is to transport oxygen from the lung to the tissue:
a. Haptoglobin
b. Bilirubin
c. Myoglobin
d. Hemoglobin

100) Responsible for cellular immune:
a. T- cell
b. B-cell
c. NK cell
d. Plasma cell
101) The Ag in ABO system:-
a. A.B.0
b. H. A.B.O
c. A.B.H
d. None

102) Reticulocyte stain with super vital to show:-
a. RNA
b. Organs
c. Network
d. Nucleus
103) In AML we see:-
a. Blast cell more 20%
b. No blast cells
c. More increase in WBCs
d. ALL

104) We done the following exam for donor except:-
a. HIV
b. HCV
c. H BV
d. H AV
105) Lipid and clot factor remove to obtain:-
a. Plasma
b. Plasma protein
c. Serum
d. Non above
106) In blood group use:-
a. Known cell with unknown serum
b. Unknown cell with known serum
c. Know cell with unknown cell
d. Unknown cell- with unknown serum

107) The gene in ABO system:-
a. A.B.O gene
b. A gene
c. A.B.H gene
d. AB gene
108) The antibody of blood group is:
a. Anti A and B
b. Anti A and C
c. Anti A and 0
d. All of the above

109) leukocyte increase in case :
a. Chemotherapy
b. Radiation
c. Bacterial infection
d. All of the above
110) Ferritin measure
a. Hemolytic anemia
b. Aplastic anemia
c. Iron diffeciancy anemia
d. Megaloblastic anemia

111) The following index sensitive and will measure the total of
iron deficiency anemia EXCEPT?
a. Transferrin
b. Fereitin
c. TIBC
d. Hb electrophoresis
112) To differentiate between hemophilia A and B
a. Leukocyte count
b. Factor assay
c. PT and PTT assay
d. All of the above

113) When the micro invades, the body B-cell will secret
antibody and it will transfer to
a. Memory cell
b. Plasma cell
c. Phygocytic cell
d. Cytotoxic
114) Poikilocytosis is:
a. Variation in red cell size
b. Variation in red cell color
c. Variation in red cell shape
d. None of the above

115) Blood plasma consists of
a. 90 % Water and 10 % other component
b. 10 % Water and 90 % other component
c. 50 % Water and 50 % other component
d. 99% water and 1 % other component
116) Arterial blood for
a. Blood chemical
b. Hormones
c. Blood gases
d. Enzyme

117) In the plain tube what happen to the sample:
a. Clotting
b. Hemolysis
c. Not doted
d. Separated
118) The HB which found in 96% is:
a. 2alpha + 2 beta
b. 2alpha + 2 delta
c. 2alpha + 2 gamma
d. 2alpha + 3 beta

119) The most common blood group is:
a. O blood group
b. A blood group
c. B blood group
d. AB blood group
120) Number of light chain in Antibodies
a. 1
b. 2
c. 3
d. 4
121) One of these test effected by slight hemolytic
a. Potassium
b. Blood glucose
c. Triglyceride
d. Cholesterol

122) ESR effected by
a. Viscosity
b. Cell shape
c. Anticoagulant
d. All of the above
123) The most problem in Pregnancy
a. Fetus +ve and mother - ve
b. Fetus - ve and mother +ve
c. Mother +ve and Fetus +ve
d. Mother -ve and Fetus -ve

124) Differential test for
a. Erythrocyte
b. Leukocyte
c. Platelets
d. Blast cell
125) Which of the following will give the best overall picture of a patient's iron stores:,
a. Albumin
b. Transferrin
c. Haptoglobin
d. ferritin
126) Increase In thalassemia
a. HbA
b. HbA2
c. HbF
d. HbS

127) Haemocytometer used in counting
a. Erythrocyte
b. Leukocyte
c. Platelets
d. Semen
e. ALL
128) Serum is plasma without
a. Lipid
b. Cholesterol
c. Fibrinogen
d. Fibrin

129) Methylen blue component of
a. Leishman stain
b. Giemsa stain
c. Sudan black
d. Gram stain
130) AB father and B mother give phenotype except
a. A
b. AB
c. B
d. O

131) Blood collect in anticoagulant tub should be
a. Gently mix
b. Clot
c. Hemolysis
d. Put in water bath 5 min
132) AML different from ALL by
a. More Increased WBCs
b. Granule neutrophil
c. Auer rods
d. More decrease WBCs

133) All are blood function except :
a. Hormone production
b. Oxygen transport
c. Nast transport
d. Buffer system
134) All the following can be done by hemocytometer except
a. RBCs
b. Semen
c. Lymphocyte
d. Total White blood cells

135) To fixation of thin blood film we can used
a. Acetone
b. Acetic acid
c. Acid alcohol
d. Not fixed
136) Normal value of Lymphocyte
a. 55%
b. 25%
c. 70%
d. 80%
137) Antigen in O negative person…
a. No presence of Ab.
b. No presence of Ag.
c. No Presence of Ab and Ag.
d. Presence of Ag A&B.

138) Rh negative patient means he does not have
a. E antigen
b. D antigen.
c. B antigen
d. C antigen
139) In O blood group the Ab in serum is
a. Anti A and B
b. Anti A
c. Anti B
d. Non A and B

140) Antigen and Anti-body can bind on
a. Ag on RBCs and Ab on plasma
b. Ab on RBCs and Ag in Plasma
c. Ag on RBCs and Ag in Plasma
d. Ag on RBCs and Ag in Plasma
141) Coombs test used for…
a. Auto antibodies on surface RBCs
b. Antigen RBCs
c. Antibodies in serum
d. Antigen on Cells
142) Test to detect whether red blood cells are more likely to
break down.
a. Spherocytosis
b. Osmatic fragility
c. CBC
d. Coombs test

143) MCHC Less than 31mg/dl
a. Microcytic hypochromic
b. Macrocytic hypochromic
c. Normocytic hypochromic
d. None
144) HDN
a. RH negative, 1gG cross to Placenta to Positive fetus
b. RH Positive, 1gG cross to Placenta to Positive fetus
c. RH negative, 1 gG cross to Placenta to negative fetus
d. RH Positive, 1gM cross to Placenta to Positive fetus

145) Vitamin D deficiency Cause
a. Rickets
b. Ulcer
c. blindness
d. Anemia
146) When it Elevated in the Blood it give Serum Milky Appear
o T. G
o LDL
o HDL
o Chylomicron + VLDL
147) Normal saline used in counting of
a. WBCs
b. Platelets
c. RBCs

d. Blast cell
148) In Stained Blood Film we can see
a. Differential Blood cell
b. RBCs shaped
c. Hemoglobin concentration
d. A & B
149) Blood group contain antigen B and antibodies A
a. A
b. B
c. AB
d. 0

150) Hbs increase in
a. Thalassemia
b. Sickle cell anemia
c. Normocytic Anemia
d. Microcytic Anemia
151) Most Found in children
a. AML
b. ALL
c. CML
d. CLL
152) Relative polyeythemia
a. Decreased Plasma Volume With normal RBCs
b. Decreased Plasma Volume With increase RBCs
c. Increase Plasma Volume With normal RBCs
d. Increase Plasma Volume With Decrease RBCs

153) Clean the Lenses of microscope
a. Water
b. Xylene
c. Ethylene
d. Normal saline
154) Duffy blood group
a. Cause hemolytic Disease and detect malaria parasites
b. Cannot Cause Hemolytic Disease and detect malaria
parasites
c. Do routinely in blood translation
d. All

155) Phagocytic and antigen presenting cell.
a. Macrophage
b. Natural killer
c. Neutrophils
d. Basophile
156) Vitamin K antagonist:
a. warfarin
b. Heparin
c. Protein C
d. Antithrombin III

157) Para hemophilia is the deficiency of
a. factor VIII
b. factor IX
c. factor V
d. factor VII
158) Eosinophilia is seen in:
a. food sensitivity
b. Drug sensitivity
c. Atopic dermatitis
d. all of the above

159) Multiple myeloma is a neoplastic proliferation of:
a. lymphocytes
b. Granulocytes
c. Plasma cells
d. Monocytes
160) With romanowsky stain ,2-5 lobes and give violet or pinkish
granules:
a. Neutrophil
b. Eiosinophile
c. Basophile

d. Monocyte
161) Lymphocyte is elevated in:
a. Viral infection
b. Acute bacterial infection
c. Iron deficiency anemia
d. Megaloblastic anemia
162) The smallest molecular weight Ig is:
a. IgG
b. IgM
c. IgD
d. IgE

163) Use O cell tube on lab for:
a. As control
b. To detect Ag
c. To detect Ab
164) In manual white blood cell count using hemocytometer the dilution
used is:
a. Normal saline
b. Sodium chloride
c. Glacial acetic acid
d. Water

165) Case of patient with hepatitis surface antigen (HB sag) history
with blood group O
The period time should not donate?
a. 1 month
b. 3 months
c. 3 years
d. Permanent
166) Reed-Sternberg cells are found in cases of ?
a. Acute lymphoblastic leukemia
b. Non-Hodgkin’s lymphoma
c. Hodgkin’s lymphoma
d. lymphoblastic leukemia

167) Hemoglobin breakdown in?
a. gut
b. kidney
c. lung
d. liver
168) Leukemia found in age 2-10 …?
a. ALL (Acute Lymphoblastic Leukemia)
b. AML (Acute myelogenous leukemia)
c. CML (Chronic myelogenous leukemia)
d. AML (Acute myelogenous leukemia)

169) Leukemia found in adults over 40 years …?
a. ALL (Acute Lymphoblastic Leukemia)
b. AML (Acute myelogenous leukemia)
c. CML (Chronic myelogenous leukemia)
d. AML (Acute myelogenous leukemia)
170) Low megakaryocyte in B.M found in …?
a. DIC (disseminated intravascular coagulation).
b. Pernicious anemia.
c. ITP (idiopathic thrombocytopenic purpura).
d. Acute leukemia.
171) Cryoprecipitate contains all this factor except …?
a. Factor VIII
b. Factor IX
c. Factor X
d. Factor XI

172) In patient serum for antibody screening in transfusion
reaction:
a. DAT
b. IAT
173) All of these are not true for reticulocytes except:
a. Supravital stain
b. Nucleated RBCs
c. Not contain RNA
d. Decrease in Hemolytic Anemia

174) Polychromatic non-nucleated red cell called …?
a. Reticulocyte
b. Erythrocyte
c. Pronormoblast
d. Late normoblast
175) MCV elevated in all of the following except …?
a. Vit B12 deficiency
b. folate deficiency
c. iron deficiency anemia

176) Which of the following is not use as anticoagulant in blood
transfusion ...?
a. Heparin.
b. Citrate phosphate dextrose adenine (CPD-A).
c. Citrate phosphate dextrose (CPD).
d. Warfarin.
e. Acid phosphate dextrose (APD).
177) Favism anemia …?
a. G6PD deficiency.
b. Vit B12 deficiency.
c. folate deficiency.
d. iron deficiency anemia.

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