Challenges of public healthcare in Malaysia as an opportunities to develop smart wearable digital healthcare solutions for global market. Specific requirements on materials and packaging technology are discussed.

1. 38th
International Electronics Manufacturing Technology (IEMT)
Conference
2018
T
I E
M
2018
MELAKA
CONFERENCE
MALAYSIA
Opportunities and Challenges for Semiconductor and
Optoelectronic Packages in the Emerging Markets of 4th
Industrial Revolution: The Case of Digital Healthcare
NorAzmi Alias
Collaborative Research in Engineering Science & Technology

2. Collaboration
Talent
R&D
Incorporated in 2011,
an Industry-led catalyst for the growth of Malaysia’s
Electrical & Electronic industry.
CREST accelerates economic growth by driving collaboration
between the Industry, Academia and Government.
CREST sparks a vibrant
R&D ecosystem by spearheading activities
in 3 key areas;
R&D, Talent Development and Commercialisation.
Our Founding & Core Members, Govt. Ex-Officio

3. CREST Board – Balance between Industry, Academia and Government
Industry
Govt. Inst.
Academia
Director
Dr David Lacey
(OSRAM)
Director
En. Farid Wajidi
Northern Corridor
Implementation
Authority (NCIA)
Chairman
Dato’ Azman Mahmud
Chief Executive Officer
Malaysia Investment
Development Authority
(MIDA)
Director
Hamdan Abdul Majeed
(Khazanah)
Director
Tan Teong Khin
(Clarion)
Director
Eric Chan
(INTEL)
Director
Firdaus Abdullah
(Silterra)
Director
Professor
Datuk
Dr. Asma
Ismail (USM)
Dato’ Dr. Mohd Sofi Bin Osman
(previously with AMD, Altera,
Intel)
Dato’ Ooi Boon Chye
(Broadcomm)
Dr Hari Narayanan
A/L P Ondiveeran
(previously Motorola Solutions)
BoardMembers
Advisors

4. We are Driving Industry-driven Collaborative R&D through
Our Key Clusters and Domain Areas
Cluster
1.
Opto-electronics,
LED and Solid State
Lighting
2.
Embedded System
& Internet of Things
3.
IC Design, Test
& Validation
4.
Advance Materials &
Packaging
5.
Electronic Smart
Manufacturing
(Industry 4.0)
6
Drones, Driverless &
Autonomous Vehicle
Domain
Area
Compound
semiconductor
engineering (III-V)
Data Analytics,
Big Data Science
Advanced testing
(IC/Board/SW) -
Probe cards, JTAG
Semiconductor
device packaging -
Multi-chip packaging
(TUV, TSV)
Industrial Automation
& Robotic
Autonomous aerial
vehicle technology
Security
Low Volume, High Mix
(adaptable
manufacturing)
Gyroscopic
stabilisation system
Thermal interface
materials
Advanced wireless
communication
Advanced Polymers Sensors & Sensing
IC Design
Automation
(cell library, IP
library, AI)
Cheaper
Epoxy/Materials for
Mass-Market
Optoelectronics
Smart Factory,
IoT in Manufacturing
Closed-loop digital
control system
High Power
Electronics
Interconnect
Energy systems -
harvesting, storage,
management
Compound
semiconductor
engineering (III-V)
Additive Manufacturing &
3D Printing Technology
GPS and
geo-fencing
technology
Optical Inspection of
semi-translucent
surface
Organic, Printable
electronic
Advanced Logic
Emulation
Nano-materials and
structures for
interconnects,
circuitry,
thermal
management
Integrated Design to
Manufacturing,
Supplier in Design
Navigation and
guidance
Smart,
Autonomous
Lighting System
Visible Light
Communication
Wearables
UI/UX-specific
SoC/IC/FPGA design
Connected Supply Chain
Lightweight
materials
MARKETS Healthcare,
Transportation,
Manufacturing,
Retail, Smart City
Materials for 3D &
inkjet printing,
flexible electronics
Computer
Integrated Mfg; Efficient
Mfg Scheduling System
Energy efficient
drives
Since 2012,
strategic
focus areas
are identified
and defined
by our key
industry
stakeholders;
revisited
every 2-3
years

5. Enable Growth in Emerging Markets
Leveraging Our Capabilities in E&E
LED & Solid
State Lighting
Embedded
System & IoT
Adv. Materials
& Packaging
Industry
4.0
Drones &
Autonomous
Vehicle
IC Design, Test
& Validation
Commercialisation
Talent Development
Collaborative R&D
Our Core Areas:
Our Current Focus Areas
* not limited to shown areas; redefined every 2-3 years and based on market needs/trends
Connected Healthcare
Precision Farming
Future Transportation
Digital Manufacturing
Smart
Sustainable Living
Since 2015

6. So Enough About CREST !!!
What are we discussing this morning ???

7. Executive Summary of This Presentation
• Over last 15-20 few years we have seen accelerated evolution of electronic and
telecommunication products from the bulky size of IBM PC, Apple Computer and
Motorola Dyna Tac phone to the thin and slim yet powerful MacBook, IPad tablet or
Samsung Tab.
• Tracking of one wellness does not have to be confined inside a hospital
with wired devices, yet replace with wearables like Fitbit, Samsung Gear, Apple
Watch or Intel-powered TAG Heuer Connected Modular 45 luxury smart watch. Adjusting to
reading needs or maneuvering the tight curves at night time could not be easier with the high
brightness LED or laser diode used in many cars.
• The continuous miniaturization of electronic devices into a wearable,
thinner and light form factor yet demanding higher computing power and
communication speed demand for new packaging schemes, substrate design and materials
• These market trends, products evolution and technology challenges will be shared to invite
views and potential collaboration discussion among the participants.

8. 4th Industrial Revolution and Emerging Markets
Connected Healthcare
Precision Farming
Future Transportation
Digital Manufacturing
Smart Sustainable Living
FinTech

9. With Digitalization Comes the Disruption
Biggest supplier of books, e-books does not publish any book
Biggest taxi company does not own any car
Largest hotel chain does not own any hotel
Largest education provider
does not have its own teachers,
content nor campusMOOC

10. What do these companies, their products and/or services have in common?
Connecting MANY buyers/users to MANYsellers/providers
Lowering the COST, TIME for buyers/users
to SELECT, PURCHASE products/services
Delivering to people BEST VALUE for buyers’/users’ MONEY
DEMOCRATIZED, DISTRIBUTED, DECENTRALIZED

11. The Case for Healthcare (Malaysia context)
http://kpkesihatan.com/2015/08/06/full-text-of-dg-of-healths-opening-address-at-the-1st-malaysian-telemedicine-conference-2015/
The current (healthcare) system may not be sustainable in the long term,
with an ageing population, increase in chronic diseases and rapid rise in
health expenditure and high out-of-pocket (OOP) spending. The total
health expenditure as a percentage of GDP has increased from RM8,303
million (2.95%) in 1997 to reach RM44,748 million (4.53%) in 2013. In
comparing public to private financing for health, the ratio has been
constant at 52+% for public to 47+% over the period of 1997 to 2013. In
2013, of the total private health expenditure, 81.13% was out-of-pocket
spending increasing the risk of catastrophic health expenditure… Dato Dr
Noor Hisham Abdullah, Director General of Health Malaysia
Same Challenges in US, Europe, Japan etc.

12. Director General of Health’s View on Future of Public Health
12
The future of healthcare is
Digitized, Decentralized and Distributed

13. * not limited to devices shown here
HIS-KKM
Driving Digital
Healthcare via
Digitised
Decentralised
Distributed
Services
3D Healthcare

14. 14
Healthcare to U is starting !

15. Mooted and
Designed in
Australia
Developed and
Manufactured in
Malaysia
Clinically
Researched and
FDA Approved in
US
The world first
AI enabled stethoscope
Dr Nayyar Hussain MD, Inventor of
Stethee and CREST’s Collaborator
Realizing 3D Healthcare Services

16. Source: Mark A. Hanson et al., “Body Area Sensor Networks:
Challenges and Opportunities,” Computer, Jan. 2009
Example of current Monitoring of
ECG for cardiovascular patient
THE MOBILE DIGITAL HEALTHCARE CHALLENGE
Mobile patch for monitoring of cardiovascular & diabetic patients, physiological conditions of first responder
in rescue mission with AI and deep learning in order to predict onset of critical conDitions
Possible solutions of mobile monitoring
of cardiovascular patients

17. MC10 – Prof. John Rogers
U. of Illinois at Urbana–Champaign Sensium Vitals – Prof Chris Toumazou
Imperial College
Bionic Skin
– Prof. Takao
Someya, U. of
Tokyo
E-Skin
– Dr. Wenlong Cheng,
Monash University,
Clayton - Australia

18. SugarBEAT – Nemaura Medical
Prof Faz Chowdhury,
Oxford University
Electrozyme (now Biolinq)
Dr. Joshua Windmiller, Prof Joseph Wang
U. of California San Diego
Prof Ali Javey
U. of Califrnia Berkeley

19. Sensionics Long-Lasting Glucose Monitoring Sensor
Encased in a biocompatible
material, the sensor utilizes a
patented fluorescent, glucose
indicating polymer technology to
measure glucose in the
interstitial fluid
The measurement and display of
glucose values is done
automatically, without the need
for user intervention.

20. Challenges on Digital Mobile Patch for Cardiovascular Disease
Vital Connect
Health Patch Biosensor
Web Biotech
SPYDER Wireless ECG
Geob Int.
Hypoband for
Hypoglycaemia
Holter Monitor
Current Wearable Healthcare Solutions
• rigid & bulky
• inflexible
• limited energy capacity
• some with wires,
• high cost to patients
• flexibility
• printable on skin
• thin film battery and wireless energy
• affordable for everyone
Future of Wearable Healthcare Solutions

21. One Possible Approach to Design Elements and Consideration
for Wearable Digital Medical Patch
www-genesys.eng.cam.ac.uk

22. Market Opportunities for Wearable Fitness & Personal Health
• Gartner Inc. and Business Intelligence
reported market for Wearable Fitness
and Personal Health will increase from
$1.6B (2013) to more than $10B (2020)
• IDTechEx reported market for materials in
wearable estimated at $25B (2025), and
these technologies are essentials;
– Flexible wearable smartphones,
– Charge directly from sunlight,
– Rolled up displays,
– Transparent electrodes, barrier
layers and nanowires
• Lux Research reported new products in
medical and athletic wearable devices
require printed, flexible and organic
electronic are estimated at US$244 million
(2018)
Wearable Products Evolution (1970-2020)
Source: Credit Suisse, 2013
$1.6B&
(2013)&
$5B&
(2016)&
Fitness&&&
Personal&Health!
2020&Market&
>&US$10B&
In&Fitness&&&Personal&
Health&
Wearable&Market&Opportunity,&2018&
Total&vs.&Fitness&&&Personal&Health&
(Gartner,&Business&Intelligence)&
<<&$1B&
$4.3B&
$14.0B&
134.27M&units&
2018
2012
2010

23. Want to Help Solve Digital
Healthcare Challenges?

24. Digital Healthcare Focus Areas
Disease-centric Use Cases
Devices
University+IndustryPartnershipsNCD-CVS
University+IndustryPartnershipsNCD-Diabetic
University+IndustryPartnershipsGrowth&Dev.
University+IndustryPartnershipsRemoteElderlyCare
University+IndustryPartnershipsRehabilitation
University+IndustryPartnershipsCD-Dengue
University+IndustryPartnershipsWellness
University+IndustryPartnershipsCD-Malaria
horizontal middleware & vertical business application
Sensors
Energy Management/Embedded Sys
Adv Wireless Communication
Common Library
Reference Model
Common Architecture
Patient Healthcare Record Database
Data Analytics
Aligned with MoH pain points as
communicated by DG of Health
since May 2014

25. Open and Targeted R&D
New Product Innovation
(Including bringing VCs, other Investors)
Prototype, MVP, Validation Ecosystem & biz enhancement
Compact
Rehab
Robot
Atrial
Fibrillation
Detection
Algorithm
Printable
ECG
Patch
Early
Breast
Cancer
Detection
Salmonell
a, E-Coli,
Listeria
PoC
System
Wide
Body
Antenna
Patient
Health
Record
Wearable
Power
Mgmt
Wireless
energy &
data
transfer
Stretchab
le
Polymer
& Ink
Aedes
Detection
System
Kinetic
energy
harvester
MyCapsule
Hypoband
CR-2
Onitor
MiniHeartCatcher
12 R&D projects
3 MNCs, 5 SMEs, 2 Start-ups,
12 Universities, Public & Private Hospitals
Projects supported through the Digital Healthcare Cluster
Technology Readiness 1-3 4-6 7-9 Commercialization Scaling and beyond

26. Our Collaborative R&D Focus Areas
Supporting Growth in Emerging Markets and Verticals
Connected Healthcare
Mobile ECG patch, AI-enabled stroke rehab
system, portable E-coli-L&S detection,
Aedes real time detection, cancer early
detection, sensor, wireless energy, medical
data analytics & AI etc.
Future Transportation
Vehicle-to-X communication, autonomous
drones-transporters, LIDAR, ADAS, hybrid
energy management system, smart ECU
system and IC etc.
Precision Farming
LED-enabled plant growth,
autonomous farm machines and
drones, IoT and AI-enabled farm
management etc.
Smart Sustainable Living
• Public Safety and security
• Commuting and mobility –
autonomous, parking alert
• Renewable energy –
distributed energy harvesting,
hybrid energy management,
micro-inverter, GaN-based
power devices
• Flood, traffic, disease alert
Digital Manufacturing
• IoT and AI-enabled process
control, manufacturing
capabilities, quality management
• Autonomous manufacturing,
automation and robotics
• Integrated demand to design,
manufacturing, warehousing and
supply chain

27. Collaborative Research in Engineering Science & Technology (CREST) Center
www.crest.my
norazmialias@crest.my