The challenges facing nonprofit organizations today are far more complex than ever before, forcing leaders to rethink their planning and place renewed focus on prioritization. But how do you help your board link their plans to realistic resource allocations? Engage in a dialogue and gather tips and tools you can use to help your board think more strategically.
Arlene A. Pietranton, PhD, CAE, executive director, American Speech-Language-Hearing Association
Kerry Stackpole, CAE, IOM, managing partner, Neoterica Partners
Workplace Change and Transition by Catherine AdenleCatherine Adenle
Is your company currently undergoing major changes that will affect you or the staff in your organization? These changes are probably in response to the evolving needs of customers. They are made possible because of the change in economy, telecommunications and digital technology. And you can expect that they will result in significant reorganisation, improvements and profitability--all will result in success that all employees will share in future but navigating the change curve for you and others will be challenging. This presentation will provide tools and resources to help you cope with the change.
Most leaders encounter resistance to change. The resistance can take various forms. People can protest the implementation plan, the approach, your leadership, the font size used in change communications, and the decision to change in the first place.
This new infographic on resistance highlights the work of three masters. Rick Maurer’s Three Types of Resistance is a classic method of understanding why people resist and how to respond effectively. Ingrid Bens teaches us how to have conversations about resistance in ways that work. The late Herb Shepard’s teachings offer wisdom from his years of work with organizations.
Use this infographic to help decide how to handle the inevitable challenges and pushback that arise during change.
Workplace Change and Transition by Catherine AdenleCatherine Adenle
Is your company currently undergoing major changes that will affect you or the staff in your organization? These changes are probably in response to the evolving needs of customers. They are made possible because of the change in economy, telecommunications and digital technology. And you can expect that they will result in significant reorganisation, improvements and profitability--all will result in success that all employees will share in future but navigating the change curve for you and others will be challenging. This presentation will provide tools and resources to help you cope with the change.
Most leaders encounter resistance to change. The resistance can take various forms. People can protest the implementation plan, the approach, your leadership, the font size used in change communications, and the decision to change in the first place.
This new infographic on resistance highlights the work of three masters. Rick Maurer’s Three Types of Resistance is a classic method of understanding why people resist and how to respond effectively. Ingrid Bens teaches us how to have conversations about resistance in ways that work. The late Herb Shepard’s teachings offer wisdom from his years of work with organizations.
Use this infographic to help decide how to handle the inevitable challenges and pushback that arise during change.
May 5, 2011 - Prsentation for members of the South Florida Organizational Development Network Regional Chapter. The presentation held at Royal Carribean Cruise Lines, Atlantic Training Room, Miami, Florida. ---------------------------------------------------------------------------
What is it all about? -----------------------------------------------------------------------------------------
According to the U.S. Small Business Administration, over 50% of Small Businesses Enterprise (SBE) in the United States fail in the first year and 95% fail within the first five years . The prevailing belief is that the majority fails because of financial difficulties. This is supported by conventional business wisdom that holds the financial and economic performance as the benchmark for SBE’s performance. However, a new research sheds some interesting light on the underlining reasons; SBEs and organizations are born premature and they focus on the wrong objectives to become successful. In this thought provoking workshop, we will explore a new definition for SBE and SBE’s decline and failure through the lenses of the EVO ModelTM . The EVO Model - Entrepreneur (“E”), business Venture (“V”) and the Organization (“O”) provides the backdrop for discussion and exploration of how SBEs and organizations can meet their strategic objectives while functioning at their respective optimal peak performance. The purpose of this workshop is to introduce a contemporary approach to the development of SBEs and organizations by focusing on the thought-behavioral-outcome process. It draws upon research in social psychology, business and management, anthropology and education. This hands-on, highly engaging and exciting workshop will conclude with a group participation exercise that will illustrate the theoretical knowledge covered in this presentation
May 5, 2011 - Prsentation for members of the South Florida Organizational Development Network Regional Chapter. The presentation held at Royal Carribean Cruise Lines, Atlantic Training Room, Miami, Florida.
What is it all about?
According to the U.S. Small Business Administration, over 50% of Small Businesses Enterprise (SBE) in the United States fail in the first year and 95% fail within the first five years . The prevailing belief is that the majority fails because of financial difficulties. This is supported by conventional business wisdom that holds the financial and economic performance as the benchmark for SBE’s performance. However, a new research sheds some interesting light on the underlining reasons; SBEs and organizations are born premature and they focus on the wrong objectives to become successful.
In this thought provoking workshop, we will explore a new definition for SBE and SBE’s decline and failure through the lenses of the EVO ModelTM . The EVO Model - Entrepreneur (“E”), business Venture (“V”) and the Organization (“O”) provides the backdrop for discussion and exploration of how SBEs and organizations can meet their strategic objectives while functioning at their respective optimal peak performance.
The purpose of this workshop is to introduce a contemporary approach to the development of SBEs and organizations by focusing on the thought-behavioral-outcome process. It draws upon research in social psychology, business and management, anthropology and education. This hands-on, highly engaging and exciting workshop will conclude with a group participation exercise that will illustrate the theoretical knowledge covered in this presentation.
Debby Hopkins, Chief Innovation Officer at Citi and CEO of Citi Ventures, has made a career out of championing innovation. Here's here advice for driving change at work.
Connect: Professional Women’s Network is online community with more than 350,000 members that discusses issues relevant to women and their success. The free LinkedIn group powered by Citi also features videos interviews with influential businesswomen, live Q&As with experts and slideshows with career advice. To learn more and join the conversation in the largest women's group on LinkedIn, visit http://www.linkedin.com//womenconnect.
Presence came together to discuss implicit bias/unconscious bias and how it impacts hiring, retention, and our experiences in the workplace. Lindsay Murdock, Inclusion Strategist discusses why we have bias, history of bias, and actionable items individuals can takeaway to combat their own biases.
Think of your DISC profile as a set of descriptors letting you know what “tools” you have in your tool belt.
Your default LEADERSHIP DIMENSION shows you which “tools” you reach for most often.
Workplace Accountability: How Effective Managers Create a Culture of OwnershipThe Business LockerRoom
Every company would love for its employees to demonstrate accountability; to take ownership of their work. However, despite their best efforts, few companies understand what it takes to create and sustain a culture of accountability. This presentation will presents the basic components of a methodology for creating workplace accountability.
May 5, 2011 - Prsentation for members of the South Florida Organizational Development Network Regional Chapter. The presentation held at Royal Carribean Cruise Lines, Atlantic Training Room, Miami, Florida. ---------------------------------------------------------------------------
What is it all about? -----------------------------------------------------------------------------------------
According to the U.S. Small Business Administration, over 50% of Small Businesses Enterprise (SBE) in the United States fail in the first year and 95% fail within the first five years . The prevailing belief is that the majority fails because of financial difficulties. This is supported by conventional business wisdom that holds the financial and economic performance as the benchmark for SBE’s performance. However, a new research sheds some interesting light on the underlining reasons; SBEs and organizations are born premature and they focus on the wrong objectives to become successful. In this thought provoking workshop, we will explore a new definition for SBE and SBE’s decline and failure through the lenses of the EVO ModelTM . The EVO Model - Entrepreneur (“E”), business Venture (“V”) and the Organization (“O”) provides the backdrop for discussion and exploration of how SBEs and organizations can meet their strategic objectives while functioning at their respective optimal peak performance. The purpose of this workshop is to introduce a contemporary approach to the development of SBEs and organizations by focusing on the thought-behavioral-outcome process. It draws upon research in social psychology, business and management, anthropology and education. This hands-on, highly engaging and exciting workshop will conclude with a group participation exercise that will illustrate the theoretical knowledge covered in this presentation
May 5, 2011 - Prsentation for members of the South Florida Organizational Development Network Regional Chapter. The presentation held at Royal Carribean Cruise Lines, Atlantic Training Room, Miami, Florida.
What is it all about?
According to the U.S. Small Business Administration, over 50% of Small Businesses Enterprise (SBE) in the United States fail in the first year and 95% fail within the first five years . The prevailing belief is that the majority fails because of financial difficulties. This is supported by conventional business wisdom that holds the financial and economic performance as the benchmark for SBE’s performance. However, a new research sheds some interesting light on the underlining reasons; SBEs and organizations are born premature and they focus on the wrong objectives to become successful.
In this thought provoking workshop, we will explore a new definition for SBE and SBE’s decline and failure through the lenses of the EVO ModelTM . The EVO Model - Entrepreneur (“E”), business Venture (“V”) and the Organization (“O”) provides the backdrop for discussion and exploration of how SBEs and organizations can meet their strategic objectives while functioning at their respective optimal peak performance.
The purpose of this workshop is to introduce a contemporary approach to the development of SBEs and organizations by focusing on the thought-behavioral-outcome process. It draws upon research in social psychology, business and management, anthropology and education. This hands-on, highly engaging and exciting workshop will conclude with a group participation exercise that will illustrate the theoretical knowledge covered in this presentation.
Debby Hopkins, Chief Innovation Officer at Citi and CEO of Citi Ventures, has made a career out of championing innovation. Here's here advice for driving change at work.
Connect: Professional Women’s Network is online community with more than 350,000 members that discusses issues relevant to women and their success. The free LinkedIn group powered by Citi also features videos interviews with influential businesswomen, live Q&As with experts and slideshows with career advice. To learn more and join the conversation in the largest women's group on LinkedIn, visit http://www.linkedin.com//womenconnect.
Presence came together to discuss implicit bias/unconscious bias and how it impacts hiring, retention, and our experiences in the workplace. Lindsay Murdock, Inclusion Strategist discusses why we have bias, history of bias, and actionable items individuals can takeaway to combat their own biases.
Think of your DISC profile as a set of descriptors letting you know what “tools” you have in your tool belt.
Your default LEADERSHIP DIMENSION shows you which “tools” you reach for most often.
Workplace Accountability: How Effective Managers Create a Culture of OwnershipThe Business LockerRoom
Every company would love for its employees to demonstrate accountability; to take ownership of their work. However, despite their best efforts, few companies understand what it takes to create and sustain a culture of accountability. This presentation will presents the basic components of a methodology for creating workplace accountability.
Data Data Everywhere: Drowning in a Sea of AnalyticsMegan Denhardt
A website gives associations access to data that makes old school direct marketers salivate. But many organizations find themselves getting bogged down in producing graphs every month, obsessing over drops in pageviews, throwing their hands up on the air, and deciding they dont have enough resources to maintain this kind of analytics analysis. Stop obsessing about the small stuff, and start learning about creating a goal-oriented, actionable analytics plan that can help your website thrive.
Lessons learned: Building Bridges for Effective eLlearningMegan Denhardt
Learn how America's Health Insurance Plans forged a cohesive and effective project team to define and articulate its complex requirements, chose an appropriate eLearning partner and worked through the implementation process to build and launch a successful program.
One of the most important and often overlooked marketing strategies is identifying and communicating your organization's unique value proposition. By understanding what characteristics distinguish your organization from others in your industry, you will be able to craft messages that are better targeted to your audiences and more effective in getting your audience to purchase from you.
Ken Esthus, account director, Marketing General Inc.
Tracy Taylor, executive director, Natural Products Foundation
Your organization has a new Facebook page with frequent Twitter updates, a YouTube channel, and every virtual bell and whistle imaginable to build your social presence. So…how do you encourage member engagement? Discuss strategies for bringing your community to life by leveraging easy-to-use tools that will take your social platform to the next level. Walk away with ideas to recognize and reward your most engaged members, generate even more viral engagement, and ultimately improve member retention.
Andy Steggles, Chief Information Officer, Risk & Insurance Management Society, Inc. (RIMS)
Membership Marketing On A Shoestring BudgetMegan Denhardt
It’s easy to develop a high-impact marketing campaign when you have millions of dollars to invest. But what if you lack the budget to compete with the big dogs – or even the big dog associations? Are you out of luck? Consigned to obscurity? Absolutely not! Join your fellow small staff association executives to share the techniques, tips and tricks that will help you stretch every marketing penny to its most productive limit.
Elizabeth Engel, CAE, Director of Marketing & Sponsorship, National Association of Children's Hospitals & Related Institutions
Kathleen Wilson, CAE, executive director, National Association of Trial Lawyer Executives
If you work in the healthcare field, this session is for you. The Trends Identification Report, written by the American Association of Medical Society Executives, will be shared and discussed. The report is written by experienced medical society executives who share their ideas on the future of health care in the US. Trends include electronic medical records and health information technology, access to health care, public health infrastructure, patient safety, quality of care, and the changing healthcare workforce.
John Jordan, CAE, executive VP & CEO, Pennsylvania Academy of Family Physicians & Foundation
Jon H. Sutton, MBA, manager, state affairs, division of advocacy & health policy, American College of Surgeons
The Legal Side Of International OperationsMegan Denhardt
Gain an understanding of the legal and cultural challenges when taking your association offshore. Discuss meetings and conference issues, how to work with with vendors and governments abroad, and trademark and intellectual property protection. Leave with a better appreciation of the legal and practical ramifications of doing business abroad.
Jonathan T. Howe, Esq., founding partner and president, Howe & Hutton, Ltd.
Kenneth Reid, CAE, executive VP, American Water Resources Association
The Buddy System Accomplishing Major Goals Through PartnershipsMegan Denhardt
To successfully accomplish major international growth initiatives, associations must often engage in partnerships with public and private sector entities to springboard the vision from design to implementation. Explore this important topic with a panel of experts and identify strategies to build your own partnerships in every corner of the globe.
Lesley-Anne Alexander, chief executive, RNIB
Len Mafrica, CAE, executive director publishing division, Oncology Nursing Society
Milagros Mostaza-Corral, director, Interel Association Management
Nikki Walker, VP, global association management & consulting, MCI Group
Todd Wurschmidt, CFRE, Ph.D., CAE, Chief Executive Officer, Paradox Associations
Shifting the Paradigm of Diversity and InclusionMegan Denhardt
An inclusive workforce boosts organizational effectiveness by lifting morale, strengthening access to new markets, and increasing productivity. Before organizations can reap these benefits, they must grow beyond simply increasing the number of affinity groups represented. Develop a better understanding of the relationship between diversity and disparities and how they affect your organization. Discover what it means to have a truly inclusive workplace and walk away with ideas and strategies you can use to reshape your organization by unleashing the power of diversity management.
Frederick Hobby, president, Institute for Diversity in Health Management
Quality Standards For Certification ProgramsMegan Denhardt
Whether you already offer a certification program or you're considering one, quality should be part of your thinking. A panel of experts will present strategies for meeting and maintaining best practices and improving your certification operations. Learn how industry standards can enable you to achieve high quality marks in all aspects of your program.
Christine D. Niero, VP, professional certification and client development, Professional Testing
Steven Schoolcraft, CSP, PE, CAE, examination director, Board of Certified Safety Professionals
Aaron White, VP/general manager, First Point Resources Management and, executive director, Cardiovascular Credentialing International
Re-Energizing Your PAC and Grassroots ProgramMegan Denhardt
Examine the key components for successful political action committees (PACs) and grassroots programs and how synergies from both can be utilized to maximize results. Discuss how these synergies will advance your government relations program. Examine proven approaches when facing PAC fatigue, how to get your organization out of a PAC rut, how to deal with competing PACs, and how to make your PAC and grassroot programs standout from the competition.
Amy Mignogna, senior manager of government affairs, Ohio Society of CPAs
Paul Williams, CAE, senior director of government relations, Assisted Living Federation of America
Using scenarios, engage in discussion around the ethical gray areas faced regularly by associations, their meetings departments and their business partners. Determine which steps should be taken to determine and encourage ethical behavior. Walk away with valuable knowledge to evaluate your policies, procedures, and practices.
Joan Eisenstodt, consultant & trainer, Eisenstodt Assocs., LLC
Practice What You Preach: World Class Engagement StrategiesMegan Denhardt
Engaged members are more passionate, more involved, more likely to become evangelists for your organizations, and more likely to continue renewing their memberships over the long term. Join one of the staff managers of the Greater Washington Network (GWN) and two volunteers to talk frankly about ASAE & The Center’s highly successful local volunteer program. Understand both the theory and practice, including the methods that work best to engage members across generations, mobilize the most individuals possible, and yield the greatest level of in-kind support possible from volunteers.
Elizabeth Engel, CAE, Director of Marketing & Sponsorship, National Association of Children's Hospitals & Related Institutions
Frances Reimers, manager, Greater Washington Network, ASAE & The Center for Association Leadership
Robert Wolfe, manager, marketing & communications, Solid Waste Association of North America
Navigating The Employment Cycle: Employer BewareMegan Denhardt
What is your organization doing to minimize risk brought about by employment liability? Identify ten areas that can trip up a nonprofit employer over the period of an employee's tenure. Avoid mistakes in the hiring and firing process, recognize and prepare for potential employment law issues, and guide your organization through the potential pitfalls lurking in the employment cycle.
Michael Buddendeck, assistant general counsel, AICPA
Lance Gibbons, of counsel, Littler Mendelson P.C.
James A. Woehlke, Esq. CAE, general counsel, New York State Society of CPAs
Associations do great work every day to improve society, but when selecting a cause to support, how do you find one that ties into your organization's mission? Listen as a 2008 Summit Award Winner advises you on which activities to undertake and how effective partnerships can help you achieve a greater good.
Steven C. Drake, president, Christmas Spirit Foundation/ Drake & Company
Matthew Shay, CAE, president and CEO, International Franchise Association
Harnessing The Basics Of Social Media In HealthcareMegan Denhardt
Understand the basics of social media as it applies to healthcare associations, gain an understanding of the necessary staff and technology investment through a case study of the American Red Cross, and walk away with ideas to better engage your members.
Ben Garrett, executive producer, On The Scene Productions, PRSA Health Academy Board
Finding Common Ground In A Shifting Economy When Membership And Cf Os UniteMegan Denhardt
Recent changes in our economy have exacerbated the differences between finance and membership professionals. A panel of CFOs and membership executives will discuss their concerns about evaluating the value of membership programs in this economy and the criteria they use to determine what programs should stay or go. Discover cost cutting tips to help you achieve your goals.
Rob Batarla, MBA, CPA, VP, finance/CFO, American Physical Therapy Association
Andrew Goldschmidt, CAE, MBA, director, membership/marketing, National Association of Counties
Susan Medick, CPA, CAE, chief financial & operations officer, Automotive Aftermarket Industry Association
Erik Schonher, MBA, VP, Marketing General Incorporated
Effective Practices For Governing A Certification ProgramMegan Denhardt
Discuss specific practices you can implement to ensure that the governance of your certification program supports the integrity required of the credential, protects the certification program, minimizes risk to your association, and serves the needs of your stakeholders.
Dale Cyr, CAE, CEO & executive director, American Registry for Diagnostic Medical Sonography
Lawrence Lynch, CAE, president, Environmental Association Management Partners
Christine D. Niero, PhD, VP, professional certification and client development, Professional Testing
Develop Social Responsibility Programs For A Global AudienceMegan Denhardt
ASAE & The Center's Global Summit on Social Responsibility showed how organizations have an opportunity to respond to a renewed call to service. Hear from organizations experienced in overseas initiatives, and explore individual and coordinated, partnership models for thinking big, doing grand work, and having life-changing effects throughout the world.
Lesley-Anne Alexander, chief executive, RNIB
Lousanne Lofgren, CAE, executive director, American Orthopaedic Foot and Ankle Society
Siada El Ramly, manager, Kellen Europe
Michelle Mason, CAE, Managing Director, American Society for Quality
Todd Wurschmidt, Interim Executive Director and Consultant, Transition Management Consulting, Inc.
Confessions Of A New CEO: Lessons Learned In My First YearMegan Denhardt
Get 10 tips for being successful in your first year as CEO. You'll hear about the mistakes made, lessons learned, and the successes enjoyed. Identify the traps new CEOs should avoid and increase the likelihood of your success as a new CEO.
Michael Fraser, CEO, Association of Maternal and Child Health Programs
Kevin Keller, CEO, Certified Financial Planners Board of Standards, Inc.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
CEO Only: Collaborate With Your Board To Achieve Your Organization’S Goals
1. Collaborate with Your Board to Achieve Your Orgnization’s Goals Arlene A. Pietranton, PhD, CAE Executive Director American Speech-Language-Hearing Association & Kerry Stackpole, EdM, CAE, IOM President & CEO Neoterica Partners
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