Cell junctions allow communication between cells and attachment to the extracellular matrix. There are several types of cell junctions: tight junctions join adjacent cells tightly to form a waterproof seal, especially in epithelial tissues; gap junctions allow small molecules and ions to pass between cells rapidly; and desmosomes connect cells laterally through cadherin proteins to keep neighboring cells together, found especially in heart, intestine, and skin cells. Hemidesmosomes attach cells to the extracellular matrix through integrin proteins in the basal layer of skin.

1. CELL JUNCTION
• Cell Junction are contact point b/w the plasma membrane
• It is also known as Cell Communication & Intracellular Bridge
• Cell to cell communication
• Cell to matrix communication

2. 1.) Tight Junctions
• Adjacent cells become tightly packed together to form a tight junctions
• Watertight Junction b/w two adjacent cells
• It is mainly found in Epithelial tissue
• Two major protein:- Occludin & Claudin
• Function:- It provides strength & stability
to tissues

3. 2.) Gap Junction
• Cell to communicate each other for rapid transfer of ions, small
molecules & sometimes big molecules
• Also called Nexus
• Most cells like epithelial, cardiac & muscle cells communicated by gap
junctions
• Functions:- allow the passage
of small water ions& molecules

4. 3.) Desmosome
• Also known as Intracellular point
• Cell to cell communication
• Arranged laterally on random side of cell membrane
• These junction keeps the neighbouring cells together
• Includs protein like Cadherins protein, linker protein, keratin protein
• It is found in Heart’s cells,
intestine’s cells, skin’s cells

5. 4.) Hemidesmosome
• Cell to matrix communication
• It is found in keratinocyte of epidermis of skin that attach to ECM
• They are similar in form desmosome
• Connects the cell, through a plaque to the
basale lamina by integrin protein

6. 5.)Adherence Junction
• It is also known as intermediate junction or belt junction
• Connects bundle of actin filaments from cell to cell & cell to matrix
• It form like belt
• Function :- Helps in changing shape of the cell

7. 🙏🙏Thank You 🙏🙏
• By Mrintunjay Kumar