Case Studies of Industry Academia Collaborations

Case Studies of Industry
Ac a d e m i a C o l l a b o r at i o n s

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Contents
Introduction.................................................................................. 8
Dynamics of Industry – Institute Collaborations.............................. 11
Case Study 1................................................................................. 14
Case Study 2................................................................................. 18
Case Study 3................................................................................. 23
Case Study 4................................................................................. 25
Case Study 5................................................................................. 27
Case Study 6................................................................................. 28
Case Study 7................................................................................. 30
Case Study 8................................................................................. 31
Case Study 9*
................................................................................ 33
Case Study 10*
.............................................................................. 34
Case Study 11*
.............................................................................. 36
Case Study 12*
.............................................................................. 37
Case Study 13*
.............................................................................. 39
Case Study 14............................................................................... 40
Case Study 15............................................................................... 41

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Academia Collaborations
8
Creation of a compendium of industry – academia
collaboration stories has been one of the long-
standing agendas of the CII National Committee on
Higher Education. The last such compendium was
published by CII in 2013 in partnership with the
Ministry of Human Resource Development on the
occasion of an international workshop on industry
– academia collaborations. That compendium had
focused only on IITs and a couple of NITs. The present
compendium goes beyond these premier institutions
to include some of those in tier II and tier III cities as
well. It provides but a glimpse of the work being done
by the two sides together.
There are several initiatives through which CII’s higher
education committee works on bringing industry
closer to academia. These include the Prime Minister’s
Fellowship Scheme for Doctoral Research which
is a public-private partnership between Science &
Engineering Research Board, Department of Science
& Technology, Government of India and CII. Launched
in 2012 at the platform of CII’s higher education
summit called the University – Industry Congress,
this fellowship has been awarded to more than 125
PhD students till date and more than 100 companies
are working with students in more than 60 premier
institutions. These partnerships are of the highest and
the ideal type – for collaborative research work which
accrue benefits to both industry and institutes.
Partnerships can, however, be of several kinds. As
a follow-up to the 2013 CII – MHRD workshop
mentioned above, CII had launched an initiative on
industry-academia collaboration called the CII 100:100.
The plan was to facilitate partnerships between 100
companies and 100 academic institutions. Under the
higher education committee, a sub-committee was set
up under the chairmanship of Dr Naushad Forbes. The
members of the sub-committee were Dr Anil Kakodkar,
Mr R Mukundan, Prof U. B. Desai, Mr Subbu Goparaju,
Dr. Arvind Bhardwaj, Dr Surinder Kapur, Dr Sanjay
Dhande, Prof Indranil Manna, Dr Prahlada, Prof Devang
Khakhar, Prof R Shevgaonkar, Mr Ninad Karpe, Mr Suhas
Baxi, Mr Ganesh Natarajan and Prof SN Mahendra. This
sub-committee identified seven different ways through
which industry and academic institutions could be
exhorted to work together. These were:-
1. Faculty sabbaticals in industry: A company
could, in consultation with its research and
HR teams, create appropriate short-duration
positions for faculty in its own office / research
laboratory. The research team could identify the
topics / issues / areas / problems and fix suitable
emolument in consultation with the HR team for
this position. The shortlisted institute could then
be informed about the topics / issues / areas /
problems identified by the research team and it
could recommend the names of one-two faculty
members. The faculty could spend two-three
months’ time at the company for which it would
be paid a consultancy fee which will be over and
above the salary he / she would be getting from
the institute. This fee will be the attraction point
for faculty to leave the institute and work on
problem-solving for industry. The exposure to real-
time challenges which such an interaction would
provide to faculty would also help in improving
their interaction with students and passing on to
them the required industry-relevant knowledge.
2. Chair professor at institute: Industry could create
an endowment to sponsor a faculty position at
a chosen department of a chosen institute for a
specified number of years. For instance, a company
with core mechanical engineering business could
select the mechanical engineering department of
an institute and give it, say Rs 50 lakh to set up a
faculty chair in its name for a period of three years.
The institute would then shortlist candidates and
appoint a suitable person, in consultation with the
company, for that chair. The chair professor would
work in close coordination with the company and
also help it on its research problems.
3. Setting up laboratories at institutes: A third
way of collaboration between a company and
an institute could be that the company sets up
its research laboratory inside an institute. The
benefit for the company would be that it will save
on land cost if it were to set up the laboratory
on its own outside. The company could also avail
financial help which the institute would get from
the government for setting up the laboratory. It
would get tax benefits for investment in R&D and
Introduction

9
also get academic researchers of the institute to
work on its problems. Research at the laboratory,
however, would not be limited to that of the
sponsoring company. Students would get to work
on latest machines and equipment which would
make them industry-ready and the engagement
would be a win-win for both parties.
4. Visiting faculty: This form of collaboration
would not require any financial commitment
from the company other than that of committing
its resources for periodic visits to institutes. The
selected companies would identify key personnel
who would be suitable for such visits and share
their profiles with CII which in turn will coordinate
with identified institutes for the exact date and
time of the visits.
5. Student internships: This form of collaboration
would also not require any financial commitment
from the company other than a commitment of
sparing time and resources to provide at least two-
month long internships to students. For this, the
company would have to identify the departments
and the maximum number of students in one
batch that it would be willing to take. The company
could also list out its expectations / requirements
from the students for this internship. CII will
work with the institutes to fix exact locations and
time of internships. Some suggestions of Prof
Shevgaonkar, the then director of IIT Delhi, in this
context were: “Internship should be for a period of
six months i.e., a summer preceding or following
semester. The colleges should increase the credits
for the internship with well-defined assessment
guidelines. For each student or for a group of
students an academic mentor be identified whose
research interests coincide with the technical
activities of that industry. This will also help in
strengthening academia-industry relationship over
a sustained period. If possible, the work carried
out during the internship should be allowed to be
extended towards the B.Tech / BE project. Industry
should accept interns for six months with adequate
financial support to make the intern financially
self-supporting. The intern should be involved in a
specific project and his / her contributions should
be reported to the academic institution with due
assessment and credit.
6. Joint research projects: Companies could team
up with PhD students registered at identified
universities / institutes / research laboratories and
develop joint research projects to be handled by
the identified student. The student, on the basis of
this partnership, could in turn apply for scholarship
under the Prime Minister’s Fellowship Scheme for
Doctoral Research. If the project was selected
by the Apex Council of this scheme, the student
would get scholarship from the government as
well as from the partner company. The per student
financial commitment under this scheme will be
approximately Rs 20 lakh over a period of four
years.
7. Lectures in video mode: For this, CEOs / CTOs/
CFOs / Research Heads of companies would have
to volunteer roughly two hours of their time
and suggest a suitable topic for a talk which CII
would arrange to video record. Technical talks
could be arranged from the machine rooms of
companies to give the viewers / students a hands-
on feel which could potentially make up for lack
of opportunities for students to visit companies.
CII would host these video lectures on its website
and depending upon the response, would work
on scaling up this initiative.
Another model of partnership was added to this list
by Prof Uday B. Desai, Director, IIT Hyderabad -- that
of Fractional Credit Courses.
In Prof Desai’s words, “We observed that it is very
difficult for an industry person, who is interested in
teaching, to devote 42 lecture hours. This has been a
bottleneck for industry persons to spend time at IITs.
Thus, we created the concept of Fractional Credit (FC)
courses – we now have 0.5, 1, 1.5 2, 2.5, and 3
credit courses each having, respectively, 7, 14, 21, 28,
35 and 42 lecture hours. These courses are graded just
like regular courses by having exams, presentations,
project report or any other innovative evaluation
process, and they appear on the student’s transcript.
At present 6 FC course credits can be counted
towards the total credits for graduation. We now
regularly have FC courses being taught by industry
persons. This way, industry is getting to know IITH
and our students and faculty are rubbing shoulders
with industry personnel. We have courses ranging
from highly technical subjects like cloud computing,
computer networks, to entrepreneurship and photo
journalism.”

10
Since 2013 when CII started championing 100:100,
partnerships have been facilitated between scores of
companies and institutes. The target of 100 has been
achieved and enlarged to CII 500:500. But efforts in
this direction continue within the higher education
committee year after year. In 2016, the chairman
of the committee Mr Vijay Thadani set up a sub-
committee on industry-academia partnerships under
the chairmanship of Dr V. Ramgopal Rao, Director, IIT
Delhi and Mr Datta Kuvalekar, R&D Head at Forbes
Marshall, Pune. This sub-committee identified certain
key barriers in scaling up partnerships:-
1. The ability of industry to define a specific problem
that needed academic rigour and had the top
management of that firm supporting the cause.
2. While IITs had a research culture and the ecosystem
to foster research collaborations, most other
institutions failed to provide a mechanism which
could foster such collaborations.
3. The connect between a known problem in a firm to
a known competence in an institution of learning
was missing. This boiled down to awareness of
expertise. There was also a dearth of platforms for
such sharing.
4. Lack of a standard template for both firms and
institutions on the basis of which collaborations
could be scaled up. This could well be termed
as “standardization” of various models of
interaction.
5. Incentivisation of such collaborations. While one
could argue that these interactions should happen
for the greater good of the country, at firm and
faculty level such interactions needed to have
a direct benefit on mutual technology / science
development. Here schemes that were available
for such collaborations could be made visible.
To create more visibility for the need to develop
partnerships between institutes and industry, this sub-
committee suggested taking the cluster approach. This
included connecting a clutch of academic institutions
with neighbouring industry clusters.
Work is afoot within CII in this direction. This
compendium highlights some of the stories of
collaborations, including some from the Prime
Minister’s Fellowship Scheme. CII would like to
acknowledge the support extended by Prof Rupinder
Tewari, Chief Coordinator of the DST Centre for Policy
Research at Panjab University for this compendium.
Five case studies illustrated in this report are sourced
from the Industry – Academia R&D Ecosystem in
India…. An Evidence-Based Study, authored by
Prof Tewari and shared by him with CII as reference
material. We would also like to thank Dr Vinnie
Jauhari, Director, Education Advocacy at Microsoft
India, for taking out the time to write a chapter for
this report on the “Dynamics of Industry-Academia
Collaborations”.
We hope that the subsequent editions of this
compendium will be able to find and highlight
many more success stories of industry – academia
collaborations.
By Shalini S. Sharma
Senior Consultant & Head – Education
Confederation of Indian Industry
Partnerships formed under Prime Minister’s
Fellowship Scheme are of the highest and
the ideal type – for collaborative research
work which accrue benefits to both industry
and institutes.

11
The world is evolving fast with digital technologies
pervading every aspect of our lives. Job market is
evolving rapidly. New technologies such as cloud,
mobility, big data are transforming the way business
is conducted and offering unique insights into better
experiences for consumers. University – industry
partnerships can go a long way in fostering deeper
learning and development of talent which industry
and universities would both cherish.
The relationship between universities and academics
can be at different levels. It could be categorized as
a step-wise process which could be looked at in four
distinct stages:
Stage 1: Getting to know each other
Stage 2: Light touch engagements
Stage 3: Deeper engagement
Stage 4: Strategic partnership coupled with
strong investments
The relationship can begin with both sides getting
to know and understand each other. The initial
interactions can be in the form of visits, round tables
and workshops.
In the first phase of collaboration, a road map for
areas of mutual interest can be drawn and the success
of initial engagement will determine the pathway
to deeper engagement. Light touch engagements
could be about a conference sponsorship, doing
few engagements with students or faculty. A deeper
engagement would require substantial investments
on both sides. It could range from one specific project
to a wider canvas of agreements. Stage four is about
a strategic partnership where there could be joint
programs, sponsored chairs, sponsored research
projects, funding of PhDs and may be infrastructure
investment as well. IIT Chennai opened the doors to
investments at their industrial park at the campus. The
industry partners were expected to spend time with
students and also mentor them on their projects. The
physical proximity of industry folks with the classes
enabled a deeper interaction rather than executives
having to travel to spend time on the campus.
Success of the partnership depends on the learning
curve for engagement for both universities and
industry. A higher degree of maturity on both sides
would also lead to engagement at a far deeper
level. However, for a large company with diversity of
interests, the willingness of various entities to engage
with academics would be at a very different level. For
excellence, vision coupled with investments to realize
the vision are important.
There are several factors that contribute to success of
partnerships between industry and academics. Some
of these are:
1. Clarity and prioritization on areas where deeper
outcomes can emanate
2. Structured framework on both sides to engage
3. Funding available for partnership
4. Ease of engagement
5. Leadership commitment
6. Laying out processes and regular rhythm to
evaluate how progress is being made
In an emerging ecosystem, there will always be a need
for a lot to do on both university and industry side.
However, on both sides, there are strict schedules
around work and studies and also bandwidth
challenges are huge. Anything that has to be done in
passing will only lead to mediocre outcomes. Based
on several years of experience on managing higher
education institute and managing university relations
from the corporate side, there are several learnings
which can be shared.
There needs to be a clarity on the vision of
engagement. The choices must be clearly laid out.
Whether it is a combination of research, working with
students / teachers / social aspects there must be a
Vinnie Jauhari, Ph.D. (IIT Delhi)
Director, Education Advocacy
Microsoft Corporation India Pvt. Ltd.
Dynamics of Industry – Institute Collaborations

12
clarity. There would always be much to do but where
can each entity add value must be clearly defined.
Prioritizing among various areas is important.
Structured framework on both sides to engage:
There should be resources allocated on both sides
to take the discussions forward. Unless there are
dedicated resources, it will be an uphill task to
have a great partnership. There are several models
that can be embraced for engagement. It could be
through business engagement or university relations
department, CSR or philanthropic engagements or a
combination of them.
Funding availability on both sides is important.
Unless there are dedicated funds in terms of investment
and resources on both sides, the outcomes would be
very limited. If research collaboration is an agenda,
then collaborative projects, sponsorship of masters or
doctoral work could be an important way to further
the area. The issues related to IP rights also need to
be addressed.
Ease of engagement is also an important area. Too
much rigidity and strict policies can be deterrent.
In a space where collaboration can be helpful, the
engagements could be lighter and much more open.
This gives a huge learning opportunity for students
and teachers. Exposure to design thinking, building
competencies around emerging technologies, building
capacity in these areas can be hugely effective.
Leadership commitment sets the culture for
engagement on both sides. If there is a commitment
from the top, the teams do get involved and tangible
outcomes can be achieved.
Laying out clear processes for engagement are
important. Regular reviews on the progress ensures
that stumbling blocks are removed.
There is much to learn from best practices of some of
the international universities on traditions of learning.
These have been student-centred learning institutes
with a good balance of teaching and research. In
all these universities which have exceled in research,
industry partnerships have played a key role which
have brought in commercial pragmatism in the system.
The confluence of all the three entities - government,
universities and industry plays a great role in
transforming the education landscape. The examples
of most developed economies prove that. Whether
it is Singapore, China, Japan, the UK, the US or
Netherlands, there are lot of similarities in the positive
role that each of the three stakeholders - universities,
industry and government played in the same.
There are several very positive examples of university -
industry engagement. There are several organisations
in industry that have worked closely with the academic
community. Infosys has a dynamic program through
which they work closely with campuses enabling
exposure for students in technical areas and building
up exposure to soft skills. Intel works with universities
to set up Intel innovation labs. HP Inc offers courses
in new technical areas. Microsoft offers Imagine
Academy through which institutions can have access
to state-of-the-art courses in tracks such as computer
science, productivity and infrastructure building in
industry certifications. It also provides avenues for
students to engage meaningfully in areas such as
cloud, app development, data sciences.
There are opportunities for students to participate in
Imagine Cup where they use technology meaningfully
to solve various problems in the ecosystem. It is a
global competition where students participate across
the globe. Adobe, Dell Computers work with schools
on building exposure to technologies. Microsoft
also works on capacity building of faculty in higher
education through its Saksham program. There
are also programs for capacity building of teachers
in K-12 through the Microsoft Innovative Educator
Expert Program. The Showcase School program is a
road map of complete transformation in learning and
embraces pathways to 1:1 learning. The Microsoft
Learning Consultants work closely with schools and
universities and help provide exposure to technologies
in education which help build 21st
century skills.
Industry also works on several solutions that help
enhance productivity in education.
Niti Aayog’s initiative - Atal Tinkering Labs is an
amazing program to support innovation and out of
The confluence of all the three entities -
government, universities and industry plays
a great role in transforming the education
landscape. The examples of most developed
economies prove that.

13
the box thinking in school students. Niti Aayog has
invited industry to also step in and extend support
to schools and expose them to innovation and new
technologies that can help them build projects to
solve problems that matter to India. Several industry
players have come forward in support and are working
with schools. Microsoft has also adopted 25 schools
to build exposure to emerging technology areas for
students and teachers in these schools.
There are several areas where this is an opportunity
to collaborate between academia, industry and
government. The government supports with
infrastructure and research grants to universities and is
taking several positive steps to build exposure of faculty
and students. Industry is a key stakeholder as it hires
from universities. Also, the partnership extends to doing
pilots on emerging technologies, testing products and
new ideas working with students and faculty.
A lot of work that happens in newer areas requires
experimentation on the side of both partners. There is a
need for working together and having mutual trust. Even
to build that a working relationship needs to be achieved
and impact needs to be demonstrated by both sides.
Evidence on success from both India and abroad
has certain commonalities. Insights from universities
in Singapore, China, USA provide enough evidence
of strong investments in developing the research
competence of faculty. They become the champions
of futuristic research and industry looks up to them for
advice and makes massive investments in funding the
research. Likewise, the policy supports the evolution
and dynamism in creating exposure to state-of-the-
art curriculum and also providing a great environment
for brightest minds to embrace the profession. There
are several lessons to be learnt from excellence
demonstrated by top universities. There has to be
a balance between great teaching institutions and
research institutions. Both have their own importance.
In both cases the gradates emanating must be life-
long learners, global citizens who are more tolerant
and peace loving, and willing to embrace change.
For this, each of the stake holders -- government,
universities and industry will have to willingly put in
their best minds to auger change.
The views expressed by the author are her own and
do not necessarily represent the views of Microsoft.

14
About CFTRI
CSIR−Central Food Technological Research Institute
(CFTRI), Mysore, is a constituent laboratory of the
Council of Scientific and Industrial Research (CSIR),
New Delhi. This premier food research institution of
India came into existence in 1950. Food Technology
being inter-disciplinary in nature the mandate or
vision of the Institute is fulfilled through various R&D
departments and support departments. Research
focus of CSIR-CFTRI is on engineering sciences,
technology development, translational research, food
protection and safety.
About General Mills
General Mills, founded as flour mill 1866, is the
world’s sixth largest food company, operating in more
than 100 countries with global sales of almost $15
billion. In India, they have a robust business and a
growing presence. Families in India know and trust
their products e.g. Pillsbury whole wheat and multi
grain Atta; Pillsbury cake mixes; Betty Crocker baking
mixes and cookie cake; Nature Valley granola bars;
Häagen-Dazs super premium ice cream. R&D focus is
on delivering innovation to grow businesses, creating
technology to shape the future, and protecting
quality.
How the collaboration began
The first meeting between the two sides took place
four years ago. From the institutes it was Dr. C.
Anandharamakrishnan, Principal Scientist, Food
Engineering Department who is also the research
supervisor of one of the recipients of Prime Minister’s
Fellowship for Doctoral Research Ms Padma Ishwarya,
S. and from industry it was Mr. Srinivasulu Naladala,
Head, R&D of General Mills India (Mumbai) and his
team of scientists from GM. The meeting took place
on the occasion of an international conference held
at CFTRI in December 2013. During the technical
discussion, Dr. Anandharamakrishnan explained the
accomplishments of his research group, especially in
the field of computational modeling for optimization
of baking process. The team of scientists from GM
was greatly impressed with this.
At the same session, Mr. Srini of GM described the
general outline of an innovative challenge of tracking
the behaviour of micron-scale dimensioned gas
bubbles in fermented bakery products, especially in
the presence of a particulate ingredient, for which
his R&D team was trying to seek solutions. From the
institute side, Dr. Anandharamakrishnan and Padma
Ishwarya gave an insight into how to go about tackling
the challenges involved in the study. The infrastructure
required for carrying out such a study on dynamic gas
bubbles in food system was sophisticated, involving
cutting-edge imaging technique and the technical
expertise to handle the same. CFTRI is well-known
for its state-of-the-art facilities to carry out any kind
of analysis pertaining to the field of food science &
technology. Hence, the sound technical credentials
of the research guide, the enthusiasm of the doctoral
student, the host institute’s established excellence in
Company: General Mills India Pvt. Ltd., Mumbai
Institute: CSIR – Central Food Technological Research Institute (CFTRI), Mysore
Project: A combined computational modeling and experimental approach to investigate the influence of
particulate ingredients on volume and structure development in baked food systems
Funding for this project was provided by both government and industry under the Prime Minister’s
Fellowship Scheme. It is a public-private partnership between Science & Engineering Research Board,
Government of India and Confederation of Indian Industry.
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Ms. Padma
Ishwarya (CSIR-CFTRI). Her academic guide was Dr. C. Anandharamakrishnan, Principal Scientist, Food
Engineering Department. Her industry mentor was Dr. Kiran Desai, Senior Scientist II, General Mills India.
CASE STUDY 1

15
the field of food research and the industry partner’s
quest to seek the solution for an innovative research
problem, were the driving factors for initiating the
academia-industry collaboration. It was during the
same time that the call for application towards the
Prime Minister’s Fellowship scheme was announced.
The institute invited GM to establish the collaboration
through the Prime Minister’s Fellowship Scheme.
Industrial relevance of the research
problem
Volume and structure development is a significant
phenomenon in baked goods systems. The interest of
the industry was to elucidate an approach to maintain
the volume even after the inclusion of a functional
particulate ingredient such as wheat bran in bread,
a popular leavened bakery product. In the above
context, the entrainment and retention of gas cells
in the structural starch-gluten network are considered
central to the volume development during bread
making process. Thus, the requirement from the
industry’s perspective were to,
• Understand and predict the bubble behaviour
during the bread making process.
• Develop insights around the bubble dynamics
which can be applied in general to baked
products category.
• Investigate the specific influence of adding wheat
bran particulates on the volume and structural
development of bread.
• Develop novel methods to modulate volume and
sensory attributes of bread whilst allowing the
incorporation of wheat bran.
Significant learnings and insights from the study were
envisaged to be of potential application in developing
product innovations across the global markets of
General Mills, mainly for boosting the fibre content in
bakery products.
Academic relevance of the research
problem
Wheat bran is a significant ingredient of industrial
relevance owing to its nutritional and nutraceutical
benefits. A long-term apprehension with respect
to bran addition in bread dough formulation is its
adverse effect on volume development. The impact
of bran addition has been considered predominantly
with respect to the volume and texture of final
product (loaf), rather than the volume and rheological
properties of dough during the intermediate stages.
The aerated structure created in mixer was considered
to have a direct effect on the final baked loaf texture.
This research study was aimed at explicating the
effect of bran addition on the development of aerated
structure. In this context, a relevant quantifying
parameter that could explain the influence of bran
addition on the evolution of aerated structure during
the breadmaking process is the ‘bubble dynamics’.
This approach is unique as bubble dynamics is often
less studied owing to its transient nature and the
opacity of dough leading to limitations in visualizing
the bubbles. The study was intended to establish that
the negative impact of wheat bran addition leading to
reduced loaf volume is routed through its influence on
bubble dynamics during the different stages of bread
making. Moreover, a comprehensive model for bubble
growth was not available in the literature, which was
proposed to be developed in this study. Nevertheless,
studying the bubble size distribution, growth and
retention are difficult in real time due to the complex
and simultaneous variations in the rheology and
interfacial properties of the dough. Thus, the present
study also aimed at developing a computational model,
to simulate the relationship between viscoelastic
behavior of dough and bubble size and use the above
to predict the influence of particulate addition on the
bubble dynamics of the bakery dough.
Furthermore, the structural properties of particulate
ingredients play a major role on the change in
dough behavior. Therefore, suitable modification of
particulate structure holds significance. Through a
thorough experimental investigation, the foremost
objective of the research work was to develop an
approach to modulate the property of wheat bran
particulate ingredient in order to achieve a high
quality of the final product.
The journey of success
With the objectives clearly mapped, the research work
was started. Discussions in frequent and convenient
intervals through tele-conference and Skype were
planned to collate the inputs from the stakeholders
of both the institution and the industry. Each stage
of the work was meticulously planned and the results
obtained were critically analyzed.
As required by the industry and instigated by the
gap-in-literature in this field of research, the bubble

16
growth mechanism in bread dough and the influence
of bran addition on the same were effectively
elucidated through an advanced imaging technology.
From the findings of this study, a new mechanism
of “coalescence-mediated bubble growth” in bread
dough was proven as the phenomenon that governs
volume development during the bread-making
process. A cutting-edge technique was employed as
the particulate engineering approach to modulate the
property of wheat bran to alleviate its negative impact
on final product quality. Compared to the dough
formulations containing whole wheat flour, the dough
with modified wheat bran resultant from the novel
approach developed in this study resulted in a 2-fold
increase in the mean bubble size of leavened dough;
improvement in bubble coalescence frequency and a
2-fold increase in the specific volume of bread loaf,
in addition to optimal sensory quality. The findings
obtained from this study were successfully used to
develop an industry relevant model which could be
applied for aerated bakery products similar to bread.
Not only for the industrial relevance, the research work
was equally lauded for its scientific depth in all the
technical forums in which the work was presented.
Outcome
Two international publications have been achieved
from this research work, in addition to two best poster
awards in 2014 and 2015 chapters of the Indian
Convention of Food Scientists and Technologists
(ICFOST), organized by the Association of Food
Scientists and Technologists of India (AFSTI). A part
of the research work was also selected for “Speaker
presentation” at the 18th
World Congress of Food
Science & Technology (IUFoST 2016), held at Dublin,
Ireland during August 2016. Notably, the chair of the
session on “Physical Properties of Foods”, in which this
work was presented, appreciated the significance of
this research with respect to its usefulness in solving
the current concerns with product quality of gluten-
free baked products and suggested that the work can
possibly be extended in the above line of research.
Two international publications have been
achieved from this research work, in addition
to two best poster awards in 2014 and
2015 chapters of the Indian Convention of
Food Scientists and Technologists (ICFOST),
organized by the Association of Food
Scientists and Technologists of India (AFSTI)
Image Courtesy: www.videoblogs.com

R.V. COLLEGE OF ENGINEERING
(Autonomous Institution affiliated to Visvesvaraya Technological University-Belagavi)
R.V. Vidyaniketan Post, Mysuru Road, Bengaluru – 560059. Karantaka.
Ph.080-67178020 / 21 Fax: 080-67178011
e-mail: principal@rvce.edu.in http://www.rvce.edu.in
Programs Offered
B.E:
Aerospace, Biotech, Civil, CSE. Chemical, ECE, EEE, E&IE,
IEM, ISE, Mechanical, Telecommunication Engg.
M.Tech (20) MCA, M.Sc (Engg.) & Ph.D Programs.
* All Departments are recognized as Research Centres by VTU *
NIRF
Ranking
(2016-17)
49th
Ranked in top 10 Pvt.
Colleges in the country
by various magazines
13 RVCE Alumni
qualified Civil Services
Exam in 2016-17
One of the Best NCC
Institute for Karnataka
& Goa Directorate
Placement
 Total No. of companies visited – 135(2017-18, till Dec. 17)
 Total No. of offers made – 902 (2017-18, till Dec. 17)
 Total No. of single offers made (No. of students placed) – 735
(2017-18, till Dec. 17)
 Highest Package: Rs. 40.0 lakhs/annum.
 Average Package: Rs. 6.05 lakhs/annum.
 Average Package for IT companies: Rs. 10.40 lakhs/ annum.
 Placement: Around 95%
Ranked 2nd in Sports
& Cultural Activities
under VTU
Infrastructure:
- Centralized Data Centre, 0.5 MW Roof Top
Solar, 980 KVA Generator Set.
- Library: Titles – 47518, Volumes – 91704,
E-Books – 29000, National Journals (Print) –
233.
- Newly built Cauvery Hostel
- Sports Centre with sophisticated facilities,
Gymnasium.
- Bank, Health Centre, Post Office, Medical
Shop, Stationery Shop, Food Court,
Repographic facilities.
Vision: “Leadership in Quality Technical Education, Interdisciplinary Research &
Innovation, With a Focus on Sustainable and Inclusive Technology”.
Estb.
1963
Accredited
by
NBA &
NAAC
MoUs: 70+ with Industries/
Academic Institutions
Executed more than Rs. 35 crores
worth sponsored research projects
& consultancy works since 3 years
Total Citations: (last 3 years)
Scopus – 1505
Web of Sciences – 1014
Google Scholar - 5381
Patents: Filed – 32 (last 3 years)
Published -08
Outcome Based Education (OBE)
- 200 credit UG courses have 50 credits
Experiential Learning and Project Based
Learning.
- Use of ICT tools including e-learning
material, QEEE, MOODLE, NPTEL,
MOOCS, Bridge Courses, as a part of Self-
study, Flipped Class Room
- Use of Online Assessment, Software
Assisted Learning, EDUSAT Programmes
and Language Lab.
- Initiation of research culture for first year
students through Journals reference for self-
study & assignment.
- 15 Industry based labs.
- Holistic development of students through
NCC, NSS, Cultural activities, Sports &
Community services.
Innovative teams
Ashwa Racing (Formula Style
Hybrid & Combustion Race Cars),
Helios Racing (All-Terrain Vehicle
(ATV)), Chimera (Hybrid Vehicles),
Garuda (Super Mileage Cars),
Vyoma (Unmanned Aerial Vehicles
(UAV)), Jatayu (Autonomous Aerial
Vehicles), Solar Car, Ashtra Robotics
(Robotics), Antariksh (Student
Nanosatellite Builder Team) and
Krushi (Tractor).
Interdisciplinary
Research Centres
Centre of Excellence in:
- Macroelectronics
- Internet of Things
- Microgrids

18
About IIT Bombay
Indian Institute of Technology Bombay (IITB)
established in 1958, was the first to be set up
with foreign assistance. The institute is recognized
worldwide as a leader in the field of engineering
education and research. Research and academic
programmes at IIT Bombay are driven by an
outstanding faculty, many of whom are reputed
for their research contributions internationally.
The department of Metallurgical Engineering and
Materials Science of IITB seeks to create an exciting,
diverse, collaborative and supportive environment
that advances in the science and engineering of
materials by developing fundamental understanding,
adopting frontier technologies, providing education
and enabling technological innovations.
About Tata Steel
The research & development and scientific services
division of Tata Steel at Jamshedpur, set up in 1937
as the ‘Research and Control Laboratory’, was one
of its kind in India. Its three departments – research
and development, scientific services and refractory
technology group – support the Tata Steel group,
particularly its operations in India and South-East
Asia, by developing new products and processes to
create competitive advantage, better environmental
performance and enhanced sustainability.
The proposed research project was initiated after
the preliminary technical discussions were held at
the company. The project was formulated to address
the important features that were missed in past
literature. It was proposed that the outcome of the
project should open up a technical possibility in
tailoring the desired microstructure. Later, the aim
of the project was divided into four objectives. The
first three objectives were dedicated to development
of a technology to improve the performance of
wires and the fourth objective was designed to solve
an industrial problem. It was also decided to have
frequent technical discussions to assess the progress
of the project. Because of the continuous of efforts
from both academic supervisor and industry mentor
the objectives were successfully completed.
Research problem
Steel wires, more specifically, patented pearlitic steel
wires, are an important component of the modern
technological society [1-5]. In 1900, Willamsburg
suspension bridge was ~500 m and used steel wire of
~1300 MPa strength. In the year 1990, on the other
hand, the bridge of Akashi Kaikyo was of ~2000 m
span and used ~1800 MPa steel cables. Even more
astonishing were the developments in steels wires for
tyre cords: strength increased from ~2.7 GPa in 1980
to ~4 GPa in the year 2000. Today, there are pearlitic
wires with strength approaching ~5-6 GPa and has
adequate ductility [3-5]. The technological possibilities
of fine pearlite, the only functional structural nano-
composite, is thus enormous.
Company: Tata Steel Limited, Jamshedpur
Institute: Indian Institute of Technology Bombay
Project: Microstructural engineering in wire rod: Possibilities
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Mr. Akula Durga
Vara Prasad (IITB). His academic guides were Prof. Indradev Samajdar (IITB) and Prof. R. D. Doherty (Drexel
University, Philadelphia, USA). His industry mentor was Dr. Saurabh Kundu (Tata Steel).
CASE STUDY 2

19
Pearlite is an important constituent of steel wires,
which imparts great strength and toughness after wire
drawing process. Manufacturing of steel wires has
multiple processing stages including rough drawing,
patenting, fine drawing, stress relieving and copper
coating or galvanizing, if necessary. Wires have a typical
composition of carbon varying within 0.65-1.3 per
cent, manganese between 0.2-0.8 per cent and other
elements in traces. The prime objective of drawing
is to increase the strength of the wire without much
reduction in ductility and fatigue resistance. Adequate
ductility ensures proper distribution of stresses during
processing of wires as well as during service. Hence,
it becomes important for any wire manufacturer to
understand the processes that determine the wire
ductility under different loading conditions. Ductility
of a wire is generally measured in terms of tensile
elongation, resistance to torsion loading and bend-
value. Each of these values depends fully or partially
on parameters such as final wire microstructure,
residual stresses, aging and surface quality. Torsional
ductility is the key parameter which decides the
performance of cables that are used in suspension
bridges. This problem was discussed by eminent
metallurgists by considering various parameters, like
inter-lamellar spacing, morphology, but no optimal /
reliable solution could be found. Thus, this project
between IIT Bombay and Tata Steel aimed to find a
solution to this much-awaited problem.
Objectives of collaboration
After several rounds of discussion, IITB and Tata Steel
laid down the following objective of this joint project:
1) Definingarelationbetweenpearlitemorphology
and ferrite crystallographic orientation
Pre-strained wire rods, supplied by Tata Steel, will be
subjected to austentizing followed by air cooling.
Morphological orientations, of the pearlite colonies
will be studied with respect to transformation
textures and anisotropic residual stress.
2) Microstructures and mechanical properties of
as drawn and laboratory annealed pearlitic
steel wires
During stress relief operation, changes in the two-
phase structure will be monitored with respect
to the residual stresses. Special emphasis will be
given of the through thickness stress relief of the
actual industrial samples.
3) Microstructural engineering in eutectoid steel:
A technological possibility
This will be done through miniature samples on
coarse pearlitic grains. The objectives were to find
out rationale behind curling and strain partitioning.
4) Study of delamination of the wires: Role of
prior drawing microstructure
This study involved the use of very sophisticated
instruments like 3-dimensional atom probe and
it is proposed that the delamination is mainly
originated from prior drawing microstructure.
Outcome of the project
This project comprised four independent, yet
interrelated, objectives, which are also independent
publications.
The project started with a controversy in literature:
Hillert’s [6] argument on the unimportance of
crystallography in pearlite growth versus experimental
observations [7,8] showing ‘uncharted’ implications
of transformation induced stresses. A combination
of EBSD and conventional metallography showed
that 2-dimensional pearlite morphology often had
‘restricted’ ferrite crystallography: a relationship
appeared to be defined by the minimum elastic
stiffness of the ferrite. These 2-d observations were
extended to 3-dimension and to coarse pearlite
colonies: clearly defining the habit plane and growth
direction of the pearlite. All these are presented in first
objective: attributing minimization of elastic strain
energy as a controlling parameter for the pearlite
growth. The possible outcome of this also indicates
a possibility of tailoring pearlite morphology through
control of ferrite crystallographic texture and state
of residual stress. This has been exploited later in
objective 1.
The strength of the pearlite is expected to depend
on a Hall-Petch type relation [9,10]. It is, however,
unknown how work hardening would affect such a
relationship. The second objective used two types of
wires: as drawn (AD) and LA (laboratory annealed).
LA wires were produced from the AD: by austentizing
and then air cooling to reform the pearlite structure.
The LA wires of the same diameter had similar
microstructures (similar alignment and interlamellar
spacing) as that of the AD, but no work hardening.
These wires, AD and LA of six different diameters,
thus provided a detailed test-matrix for relating the

20
mechanical responses with different microstructural
parameters. For example, it was shown that work
hardening did not affect tensile yield strength: but
influenced the ductility (both tensile and torsional
and torsional strength. Strengths, both tensile
and torsional, were controlled by the interlamellar
spacing; while pearlite alignment was a critical factor
in determining torsional ductility. The knowledge
emerging from this objective 2 is new, it also suggests
possible technological applications for the LA wires. A
combination of objective 1 and objective 2 indicates
possibilities of tailoring pearlite microstructure to
achieve desired tensile and torsional properties. And
that constituted objective 3.
Inobjective3,thewirerodspecimensweresubjectedto
controlled thermomechanical processing: application
of different cooling rates and / or external stresses
during austenite-pearlite phase transformation.
These enabled major changes in pearlite alignment,
and minor (albeit consistent) changes in interlamellar
spacing. Interestingly, in the absence of significant
residual stresses, the pearlite alignment was still
controlled by the ferrite crystallographic texture.
The microstructural engineering (through improved
axial alignment of pearlite) through controlled TMP
gave a four-fold increase in torsional ductility. TMP
of eutectoid steel thus appears to have interesting
technological possibility. Of course such a possibility
remains to be tested in the actual industrial
environment, but a clear implication of objective 3 is
reflected on objective 4.
Objective 4 originated from a live industrial problem.
The industrial partner reported occasional (10 per
cent < of the actual production) delamination
of pearlitic wires subjected to a drawing strain of
~2.5. The original wire rods, with post wire drawing
delamination, had noticeably lower axial alignment of
the pearlite: 22±5 per cent versus 34±4 per cent in
the non-delaminated wires. Carbide dissolution and
formation of supersaturated ferrite were the clear
cause for the delamination, which was effectively
mitigated with controlled laboratory annealing.
These results are indeed expected. The novelty of this
objective started with direct observations on ‘top-hat’
specimens. They revealed significant differences in
work hardening and in shear localizations. These were
controlled by pearlite morphology and interlamellar
spacing. Prior-drawing microstructure of coarse
misaligned pearlite thus emerged as a critical factor
in the wire drawing induced (and potentially pre-
mature) delamination of the pearlitic wires.
Uniqueness and benefits of the project
This project helps in better understanding of the
transformation of austenite to pearlite in steel.
With this knowledge, we have successfully modified
the microstructure by controlling the cooling rate.
The wires with this microstructure enables the
improvements in torsional ductility by four times.
The new route suggests the application of blowing
air instead of using lead bath. The usage of lead
bath in industry could affect the environment, so, by
adopting the new processing route, one can avoid the
lead bath practice. This is the major contribution to
the environment as well as to the society.
References
1. M. Elices, M. Elices, Journal of Materials Science 39
(2004) 3889 – 3899:
2. M. Zelin and R. M. Shemenski, Wire Journal International,
August 2007, pp. 69-73.
3. G. Langford, Metallurgical Transactions A, 1977, n. 1,
pp. 465-477.
4. E. Doege, Steel Wire Technology, Applied Materials
Technology, Material teknik, Sweden.
5. Yang et al, Materials Science and Engineering: A, Volume
508, Issues 1-2, 20 May 2009, Pages 148-155.
6. M. Hillert, “The formation of Pearlite” in Decomposition
of Austenite by Diffusional Processes (edited by V. F.
Zackay and H. I. Aaronson), Interscience (a division of
John Wiley and Sons/New York), 1962.
7. S. A. Hackney And G. J. Shiflet: Scripta Metall., Vol. 19,
Pp. 757-762, 1985
8. M. J. Whiting And P.Tsakiropoulos, Scripta Metall Et
Mater, Vol. 32, No. 12, Pp. 1965-1966, 1995.
9. J. D. Embury and R, M. Fisher: Acta Met., 1966, Vol. 14,
p, 147-159.
10. G. Langford, Metall. Trans. A. 8 (1970) 121 – 132.
It was also decided to have frequent
technical discussions to assess the progress
of the project. Because of the continuous
of efforts from both academic supervisor
and industry mentor the objectives were
successfully completed.

21
Publications from this project
1. Durgaprasad. A, Giri. S, Lenka. S, Kundu. S, Mishra. S,
Chandra. S, Doherty. R. D, Samajdar. I, (2017) “Defining
a relationship between pearlite morphology and ferrite
crystallographic orientation”: Acta Materialia, vol. 129,
pp. 278-289.
2. Durgaprasad. A, Giri. S, Lenka. S, Kundu. S, Mishra.
S, Chandra. S, Doherty. R. D, Samajdar. I,: (2017)
“Microstructural and Mechanical properties evolution
during wire drawing of pearlitic steel wires”: Metall.
Trans A., vol. 48, pp. 4583-4597
3. Durgaprasad. A, Giri. S, Lenka. S, Kundu. S, Mishra.
S, Chandra. S, Doherty. R. D, Samajdar. I: “Effect of
controlled Thermo-mechanical processing on pearlite
morphology”: Under review “Metallurgical and
Materials Transactions-A”
4. Durgaprasad. A, Giri. S, Lenka. S, Kundu. S, Mishra. S,
Chandra. S, Doherty. R. D, Samajdar. I. “Delamination of
Pearlitic Steel Wires: The Defining Role of Prior Drawing
Microstructure”, Under review “Metallurgical and
Materials Transactions-A”

23
AboutManipalCollegeofPharmaSciences
MCOPS comes under Manipal University. It has
infrastructure to conduct research in all major disciplines
of pharmaceutical sciences including formulation
development, drug discovery and development studies,
molecular and cellular levels studies, herbal drug
development, clinical research and quality assurance.
Strand Life Sciences
Strand Life Sciences, formerly Strand Genomics, is
a Bangalore-based in silico technology company. Its
key focus areas are data mining, research biology
to develop software and services for life sciences
research. Strand Life Sciences was founded in October
2000 by Dr Vijay Chandru, Dr Ramesh Hariharan, Dr
Swami Manohar, and Dr V. Vinay. The company now
also focuses on core life science, especially, running
cancer samples in NGS platform and precision
medicine using liquid biopsy samples.
Project background
While pursuing a project on ABC transporters in breast
cancer, Dr. Vaijayanti Gupta of Strand Life Sciences was
looking for a research lab and dedicated researcher to
solve an industrial problem on drug resistance.
Sai Balaji Andugulapati, a key researcher working on this
project finished his M. Pharmacy in Manipal College of
Pharma Sciences and then joined as a Junior Research
Fellow in Dr. Annapoorni Rangarajan’s lab in Indian
institute of Sciences (IISc) Bangalore. He was working in
the area that Strand Life Sciences was interested in. The
company suggested that Balaji does his PhD on the topic.
Sai Balaji, registered for PhD in MCOPS, got selected for
Prime Minister’s Fellowship for Doctoral Research.
Sai Balaji started pursuing his PhD with the combined
research problem on ABC transporters, titled ‘Study the
role of ABCC family of drug transporters in cancer chemo
resistance’. While conducting initial experiments, the
team observed that few controls that were important to
complete the project were missing - live animal imaging
and flow cytometry instruments. The research team
approached Strand Life Science and suggested that
they collaborate with Dr. Annapoorni Rangarajan (IISc)
to complete the experimental problems. With great
inputs and guidance from Dr. Annapoorni Rangarajan,
Dr. Vaijayanthi Gupta and Dr. N Udupa, the research
work was successfully completed. The researcher
too finished his PhD and published his work in good
peer reviewed journals. He published his work in 6
international journals. He also worked on other projects
and published in 7 more international journals.
Project outcomes
Sai Balaji worked majorly on breast cancer especially
on drug resistance. In this study, the group (Sai Balaji,
MCOPS, IISc and Strand Life Sciences) examined the
expression of ABCC3 in breast cancers and studied
its role in drug resistance and stemness of breast
cancer cells in comparison with the more studied
ABCC1. It was observed that similar to ABCC1, the
transcripts levels of ABCC3 was significantly high in
breast cancers compared to adjacent normal tissue.
The study highlights the importance of ABCC3
transporters in drug resistance to chemotherapy in the
context of breast cancer. Further, these results suggest
that combinatorial inhibition of these transporters
together with standard chemotherapy can reduce
therapy-induced resistance in breast cancer.
Company: Strand Life Sciences
Institute: Manipal College of Pharmaceutical Sciences & Indian institute of Sciences (IISc) Bangalore
Project: Study the role of ABCC family of drug transporters in cancer chemo resistance
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Mr. Andugulapati
Sai Balaji. His academic guides were Dr. Annapoorni Rangarajan (IISc), Dr. N Udupa and Dr. C Mallikarjuna
Rao. His industry mentor was Dr. Vaijayanti Gupta, Strand Life Sciences.
CASE STUDY 3

RAISONI GROUP
a vision beyond
In 5
Years
153
Patents
Filed
Pan India
Rank
within 10.
IN
INDIA
BY
RAE NC K
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Top innovator award of DST-CII-AICTE initiative, ranked in
Gold category as per 2015 and in Platinum category as per 2016
AICTE-CII survey report.
• Credit transfer scheme with
COEP & VJTI
• Incubation Center
• Involvement of experts from IITs,
NITs and industries incurriculum
design Learner centric system
• More electives with prerequisites
• Open Elective
• Choice Based Credit System with
Relative Grading
• Re-examination within a month
• Interdisciplinary Subjects
• Projects Every Year
• Open Ended Experiments
• Short term certiﬁcate courses
• Self study based on ICT,
communication skill courses
• 15% syllabus updated every year
• Teachers Assessment through
Quizzes, Seminars, Assignment etc.
• Activity Based Learning
• Remedial Teaching at Multi levels
• Psychological counseling
• Mandatory 6 months Industry
Internship
• QEEE center with IIT Madras
• Grade Improvement during
Degree
Our USP
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Providing Engineering Education
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with TEQIP-I & II
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/ghrce.nagpur.live @ghrce_nagpur
CRPF Gate-3, Digdoh Hills, Hingna Road, Nagpur-16
M : 09921008657, 9604787184, 9881711791, 9922083322
W : www.ghrce.raisoni.net | E : principal.ghrce@raisoni.net
G H Raisoni
College of Engineering
shellsindia.com
Ÿ 3000 Plus Students Completed 6 Months Internship in 700 Plus Companies
Ÿ 100 Plus Industry Experts involved in Project & Internship Evaluation
Ÿ Rs. 1Crore plus received as stipend by students
Ÿ 50 Plus Industry experts on Board of Studies and Advisory Boards
Ÿ 06 Industry Funded Labs Worth Rs 50 Lakhs
Ÿ by Yamaha, Mahindra, Intel, National Instruments, Texas Instruments and
Xilinx
Ÿ 10 Campus Companies through unique ‘Campuspreneur’ Programme in
Association with TiE
Ÿ 300 Plus Alumni Entrepreneurs
Ÿ G.H.Raisoni Incuabtion Centre forn urturing young entrepreneurs mentored
by IIM experts
Ÿ Institute selected for PMYUVA Programme by Government of India
Ÿ 30 plus Prizes at Technical Competitions organized by IITs, CII, IEEE and other
organizations

25
About Saurashtra University
Saurashtra University (SAU), established in 1967,
is situated in Rajkot city of the Saurashtra region of
Gujarat. The campus is spread over 360 acres. There
are 28 post-graduate departments and 297 affiliated
colleges. SAU’s core mission is to promote sustainable
growth and economic independence in rural society.
The university works towards the empowerment of
farmers. Biotechnology department serves as a centre
for academic excellence in the areas of post-graduate
and human resource development in agricultural
science. The department provides opportunities for
post-doctoral research, continuing education, faculty
upgradation and development of human resources in
new and cutting-edge technology areas.
About Solar Agrotech
Solar Agrotech is a distributor of certified cotton
seeds under the brand name “Doctor Seeds”. They are
certified collaborators of Mahyco Monsanto Biotech
(I) Ltd. The company has sound R&D base and has
three research farms at different.
The company wanted to explore new dimensions
in microbiological products. It had identified critical
problems associated with cotton farming. These were
two serious fungal wilt diseases that cause great harm
to cotton yield. R&D team investigated the problem and
came up with a proposal to overcome the problem. Mr.
Hiren Sherathiya, who was a Ph.D. scholar of Saurashtra
University, Rajkot and had registered with the research
title, “Isolation and evaluation of anti-pathogenic
bacteria from cotton rhizosphere” came in contact
with the company. The research project that he had
proposed had been identified as one of the suggested
solutions of the above-mentioned problem. So the
company got ready to share work and facilities for this
research and took the opportunity to use outcome of
research for their benefit.
While the company was initiating steps to develop
biological products for agricultural purposes, there
was no sound facility for microbial work. Also, the
company wanted to expand these facilities in their
laboratory, which was assisted by the institute. On the
other hand, the institute did not have facilities and
expertise to carry out field trials of cotton, one of the
important objectives of the work which was facilitated
by the company.
Project outcome
The research project ended with finding out of anti-
pathogenic plant growth promoting bacteria which
have sound possibilities to develop into a good
biological product for the company. This collaborative
work also helped the institute in finding out on-
ground research problems of farmers with successful
outcomes of field trial.
Company: Solar Agrotech Private Limited
Institute: Saurashtra University
Project: Isolation and evaluation of anti-pathogenic bacteria from cotton rhizosphere
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Mr. Hirenkumar
Mansukhbhai Sherthiya.
CASE STUDY 4
This collaborative work also helped the
institute in finding out on-ground research
problems of farmers with successful
outcomes of field trial.

27
About Bombay College of Pharmacy
Bombay College of Pharmacy (BCP) is a pioneering
institution in pharmaceutical education in India. It
was founded in 1957 by the Indian Pharmaceutical
Association - Maharashtra State Branch with financial
assistance from the Government of Maharashtra
and several pharmaceutical corporations. Since its
inception as a college offering a Diploma in Pharmacy,
the college has grown in stature and at present offers
Bachelors, Masters, and Doctoral programs of study
in pharmaceutical sciences.
About BASF SE
BASF SE is a German chemical company and the
largest chemical producer in the world. The BASF
Group comprises subsidiaries and joint ventures in
more than 80 countries and operates six integrated
production sites and 390 other production sites in
Europe, Asia, Australia, the Americas and Africa. Its
headquarters is located in Ludwigshafen, Germany,
and has customers in over 190 countries and supplies
products to a wide variety of industries.
Project background
BASF is highly active in supporting academic research
and this interest led to its collaboration with BCP for
developing computationally economic methods to
predict and understand drug resistance.
Research collaboration
The project was funded for a period of three years and
it ended in December 2016. The main objective of
this project was to help BASF biochemical scientists to
understand drug resistant mutations for few of their
marketed drugs by developing computational models.
The work was carried out by Prof Evans Coutinho’s
group at BCP and closely supervised by BASF scientists
Dr Ian Craig and Prof Dr Klaus-Jürgen Schleifer.
Present status
The major hurdle in this project was dearth of literature
data for the enzymes that witnessed mutations and
therefore it was difficult for the research team to
validate many of the computational results. However,
at the end of the project, the biochemists at BASF had
enough knowledge from the computational models
and methods to progress their biochemical work in
the right direction.
Company: BASF SE
Institute: Bombay College of Pharmacy
Project: Developing computationally economic methods to predict and understand drug
resistance
CASE STUDY 5
Image Courtesy: ZEISS Microscopy

28
About Loba Chemie
Loba Chemie is a company with five decades of
experience in laboratory reagents and fine chemicals.
With the recent expansion in restructuring life science
industry over the last decade, Loba Chemie has
diversified into entire new range of contract research,
pharma synthesis and R&D activities including QA
& regulatory support and scale up R&D facility with
industrial capabilities.
Project background
The company approached Prof. Krishnapriya Mohanraj
of Bombay College of Pharmacy for chiral separation
work.
Prof. Krishnapriya Mohanraj and her team had
used a chiral selector (as mobile phase additive)
for enantiomeric separation of several chiral active
pharmaceutical ingredients (APIs) by reverse phase
high performance liquid chromatography (RP-
HPLC) using non-chiral columns. The chiral selector
had to be imported from sigma aldrich. The team
developed a cost effective indigenous method for
synthesis of the chiral selector with around 150 per
cent reduction in cost. The synthesized chiral selector
also showed better performance for enantiomeric
separation (better resolution and less run time) than
the commercial imported product.
Present status
Loba Chemie showed interest in commercializing
production of the chiral selector synthesized in
a cost-effective manner. The technology transfer
was effectively executed with a Memorandum of
Understanding (MOU).
Company: Loba Chemie Private Limited
Institute: Bombay College of Pharmacy
Project: Chiral separation work
CASE STUDY 6
Image Courtesy: http://vijaychemicals.co.in

30
Uniqueness of the Project
Pigeonpea or arhar or toor dal is a major legume
crop in India and is an important source of protein
in Indian vegetarian diet. Its plant grows very slowly
in the initial phase of 45-50 days which is when it
is most susceptible to damage by weeds and pests
such as blister beetle. The aim of this research was to
develop bioagents to control the infestation by blister
beetle specially with relevance to Punjab.
How it benefits Society
The bio-pesticide developed through this research
project is safe for environment. It is less expensive than
concoction pesticides and is thus more affordable for
farmers. In future, potent strains could be tested in
Company: Sampurn Agri Ventures Private Limited
Institute: Punjab Agricultural University, Ludhiana
Project: Characterization of native bacillus thuringiensis isolates against mylabris pustulata thunberg in
pigeonpea and optimization of bioprocess parameters
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Ms Babita
Mukhija. Her academic guide was Dr Veena Khanna, Senior Microbiologist at Punjab Agricultural University
and her industry mentor was Mr Sanjeev Nagpal, CEO of Sampurn Agri Ventures.
CASE STUDY 7
various agricultural zones all over the country for
commercialization of the product to generate revenue
for farmers by enhancing the yield of the crop.

31
Uniqueness of the project
Black carrot and soybean are amongst the targeted
crops rich in bioactive anthocyanins worth utilization
as natural colorants. Industrial application demands
efficient and fast recovery extraction strategies.
The research devised enzyme and microwave-
assisted extraction strategies, established the color
enhancing and stabilising properties of heat sensitive
anthocyanins from other fruits.
Company: Prathista Industries Limited
Institute: ICAR-Indian Agricultural Research Institute, New Delhi
Project: Anthocyanins as ingredients for food industry: Strategy for extraction, functional characterization
and enhanced stability
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Mr. Manoj
Kumar Puniya. His academic guide was Dr Anil Daduja, Principal Scientist at IARI and his industry mentor
was Dr. KVSS Sairam, President of Prathista Industries.
CASE STUDY 8
How it benefits society
Enzyme and microwave-assisted extraction have
promising industrial applications for extraction
of anthocyanins from black carrots and soybean.
Co-pigmenting anthocyanins with other juices is an
effective strategy to impart high thermal stability,
improve color retention and antioxidant activity. These
strategies could serve as valuable guide to industry for
functional food market.

33
This partnership between the Surat, Gujarat-based
Sahajanand Medical Technologies and ICT Mumbai
has resulted in availability of superior and 25 per cent
cheaper products for patients. It has led to 4 coronary
stents being marketed in India and abroad under the
trade names Infinnium, Supralimus, Supralimuscore
and Everoflex. Other stents under development are
S-Link and Supraflex. More than 3.5 lakh stents have
been implanted since 2013-14 and the company has
generated a revenue of Rs 50 crore till date.
The project was partly funded by the Prime Minister’s
Fellowship Scheme for Doctoral Research which
is a public private partnership between Science &
Engineering Research Board, Department of Science &
Technology, Government of India and Confederation
of Indian Industry.
It was the industry partner who approached the
institute and they were involved in the project right
from conceptualization to patent filing, scale-up, pre-
clinical and clinical studies, product approval from
authorities and marketing.
The duration of this partnership was nine years and it
started in 2006. There were gains for all three partners
in this project. The institute got 25 per cent of the
project cost as well as 33 per cent of the consultancy
cost. Add to that, the prestige that it brought to its
name and reputation. The principal investigator’s
name became part of the patent which was generated
from this research and he got several publications to
his credit in the process.
Company: Sahajanand Medical Technologies Private Limited, Surat
Institute: Institute of Chemical Technology, Mumbai
Project: Development of novel drug eluting coronary stents
CASE STUDY 9
*
The company gained by getting entry in the global
market (over 40 countries) with superior coronary
stents. It became the first company in India to receive
the European Conformity (CE) mark. Regulatory
authorities in India not only approved the products
but also increased the shelf life from initial one year to
2.5 years for Supraflex in 2015.
*
Case study taken from Industry – Academia R&D Ecosystem in India…. An Evidence-Based Study; Courtesy Prof Rupinder
Tewari, Chief Coordinator, DST-Centre for Policy Research at Panjab University, Chandigarh
Image Courtesy: http://newsroom.cumc.columbia.edu

34
The collaboration between Mumbai-based IPCA
Labs and Panjab University has led to liposome and
nano-technology based novel pharma products for
dermatological disorders such as psoriasis, eczema
and fungal infection stability solutions.
The responsibilities of academia in this project were
concept formation, hypothesis testing, generation of
scientific lab-scale data and scientific evidences, varied
techniques for analysis, pre-formulation, formulation
development, characterization and standardization,
stability issues and assessment, package development,
product technology information.
Industry was responsible for scale-up and technology
transfer, joint development of standard operating
procedures (SOPs), filling all the gaps to fulfil the
Company: IPCA Labs Private Limited, Mumbai
Institute: Panjab University, Chandigarh
Project: Development and scale-up of some novel liposomal products
CASE STUDY 10
*
regulatory requirements, funding support for
materials and outsourcing, fellowship for scholars
and support for lab assistance and patent filing.
Other organizations which provided funding support
for infrastructure and high cost instruments included
University Grants Commission, All India Council for
Technical Education, Department of Bio-technology
and Department of Science & Technology.
The university shared with the innovator the royalty
amount, i.e., 2 per cent of ex-factory price which was
then distributed 50:50 between the university and
the investigators. The collaboration enhanced the
employability of scholars. They were quickly absorbed in
the high growth and top performing pharma companies
such as Sun Pharma, Lupin, IPCA and others.
*
Image Courtesy: http://knkx.org

36
This project was unique in the sense that it was led
largely by the industry partner, more specifically
the Founder and Managing Director of Lifecare
Innovations, Dr J N Verma. In 1990s, Dr Verma was
the only known liposome technologist in Indian
industry credited with discovery, development and
commercialization of Asia’s first liposomal product -
Liposome Agglutination Test for immune-diagnosis
of Syphilis. Various government agencies such as
DBT, NRDC and DSIR had identified Dr Verma and
committed support for creating the company Lifecare
Innovation to absorb DBT technology, carry out
translational research and commercialization of life-
saving drug for treatment of life-threatening fungal
and leishmanial infections. It was Dr Verma who
approached academia for collaborative research.
Today Lifecare Innovations has forged several
collaborations both within and outside India and
has become inspiring example of technology led
enterprise engaged in discovery and development of
novel drugs.
Company: Lifecare Innovations Private Limited, Gurgaon
Institute: Seth GS Medical College and KEM Hospital, Mumbai
Project: Scale-up process development for production of liposomal amphotericin B, awareness program
and clinical performance trials
CASE STUDY 11
*
The outcome of this project was that Fungisome the
only indigenous drug which is also superior to imported
Liposomal Amphotericin B (i.v.) was innovated,
commercialized and made available throughout India
and became preferred Liposomal Amphotericin B (i.v.)
of most of the premier hospitals in India including
AIIMS, New Delhi; PGIMER Chandigarh; Sanjay Gandhi
Post Graduate Institute of Medical Sciences, Lucknow;
Christian Medical College (CMC), Vellore; Tata
Memorial Hospital, Mumbai; Medanta-the Medicity,
Gurgaon; Apollo Group of Hospitals, New Delhi and
defense hospitals. The daily dose cost, success rate
and nephrotoxicity of Fungisome were 5900, whereas
that of the imported AmBisome were 60,000. Prior to
Fungisome, only 1 per cent of the patients needing
Amphotericin B could afford its nephrosafe Liposomal
formulation whereas within three years of Fungisome
launch, Fungisome alone catered to estimated 16 per
cent of the patients needing Amphotericin B (i.v.).
Today Fungisome is emerging as a drug of choice in
several countries. It has been launched in Latin America
under the brand name AmBullet.
The institute was paid royalty for this project.
Scientists involved in the project benefitted by getting
unprecedented recognition. In addition to other
honors and awards, the principal investigator from
KEM Hospital, Mumbai, Dr. Neelima Kshirsagar, was
conferred with B.C. Roy Award.
Today Lifecare Innovations has forged several
collaborations both within and outside India and
has become inspiring example of technology-led
enterprise engaged in discovery and development of
novel drugs.
*
The institute was paid royalty for this project.
Scientists involved in the project benefitted
by getting unprecedented recognition. In
addition to other honors and awards, the
principal investigator from KEM Hospital,
Mumbai, Dr. Neelima Kshirsagar, was
conferred with B.C. Roy Award.

37
Company: Thermax Private Limited, Pune
Institute: Indian Institute of Technology, Delhi
Project: Flow studies, mixing pattern and modeling of rotary bioreactor
CASE STUDY 12
*
*
The duration of this project was two years and it
received funding from various agencies. Maximum
funding came from Thermax – of Rs 60 lakh.
Department of Science & Technology gave Rs 37
lakh; IIT gave Rs 30 lakh; Ministry of Human Resource
Development contributed Rs 25 lakh and the Board of
Research in Nuclear Sciences gave Rs 20 lakh.
The technology for flow imaging developed at IIT-
Delhi was never used in the industry directly. It was
a challenge to do so, and this was the first ever
(anywhere in the world) that successful demonstration
and use of this technique was made in industry.
The suspected problems were fully addressed and
specific recommendations were made. Some minor
design changes and major operational changes were
made. Good efficiency was ensured and product /
technology was a commercial success in the market.
It is today marketed under the brand name “BioCask”.
It is today an important technology for end-to-end
wastewater and sludge treatment.
Role of the academic institution in this case was
conduct of in-house (in IIT) experiments, establishing
the experimental protocol and conduct of experiments,
collection and analysis of data and modelling of
flow phenomena. The company took care of design
of experimental unit, fabrication and installation.
It provided logistical and manpower support for
scientists from IIT and BARC.
Image Courtesy: www.vijetha.net

-Ph.D(DepartmentofChemistry)
MAJORRECURUITERS

39
The duration of this project was only three months
and industry partner provided Rs 6.5 lakh for it. The
responsibility of the institute was to design efficient
solar operated irrigation pumping system and the
company provided specifications for the requirement.
The company was able to get a commercial product
Company: BSES Yamuna Power Limited, New Delhi
Institute: Indian Institute of Technology, Delhi
Project: Solar power operated water pump
CASE STUDY 13
*
within a short time period. It successfully marketed
these water pumps later on in Delhi. The intellectual
property from the project was equally shared between
the institute and industry. The collaboration led to
improved water supply by reducing dependency on
electricity to run the pumps.
*
Image Courtesy: Shakti Helical Pump, from www.linkedin.com

40
Uniqueness of the Project
The project has led to development of a hydrogel
scaffolding technology for stem cell transplantation in
brain. The technology solves the problem of cellular
death and migration, post transplantation in the brain.
The hydrogel also helps in differentiation of stem cells
from neurons inside the brain.
Company: Piramal Enterprises
Institute: IITB-Monash Research Academy, Indian Institute of Technology, Bombay
Project: Engineering amyloids for nanotechnology and neuronal cell regeneration
Researcher of this project, who was also the recipient of Prime Minister’s Fellowship, was Mr. Subhadeep
Das. His academic guide was Prof. Samir K Maji, Associate Professor at IITB; Prof. John S Forsythe,
Associate Professor at Monash University and his industry mentor was Mr. Neelay Desai, Senior Vice
President, Piramal Enterprises.
CASE STUDY 14
How it Benefits Society
Stem cell therapy can completely cure debilitating brain
diseases such as Parkinson’s. This hydrogel technology
solves the current limitations of the therapy by helping
stem cells to survive as well as grow into neurons inside
the brain, bringing stem cell therapy for Parkinson’s
patients one step closer to reality.
Image Courtesy: http://www.huffingtonpost.in

41
Bhooma Energy Ventures
Bhooma Group, which began as an export-import firm
in 1990 in Mumbai, has interests in plantations, bio
fuel production, commodities and it produces energy
through waste management processes and plants.
The group works in the area of sustainable, innovative
and eco sensitive energy solutions. Bhooma Energy
Ventures has its primary focus on renewable energy
and it derives value out of waste. Bhooma Bio Fuels
focusses on bio-mass diesel generation.
IIT Guwahati
Indian Institute of Technology Guwahati is a public
institution established in 1994 by the Government
of India, in the state of Assam. It is the sixth Indian
Institute of Technology to have been established in
the country. The Institute conducts research within
its academic programmes under all departments and
academic centres. Its faculty members also conduct
research projects sponsored by various government
agencies and companies. The aim of these sponsored
research projects varies from advancement of
theoretical knowledge to development of new
technology to solving practical problems. As of March
2014, the institute had 350 research projects of total
sanctioned value of Rs 198 crore. It had applied for
37 patents out of which six had been granted and six
technology transfers completed.
Project background
A high percentage of energy consumed worldwide
comes from petrochemical sources, coal and natural
gases which are depleting at an alarming rate. The
problems caused due to the combustion of fossil
fuel call for search for cleaner energy alternatives
from renewable sources. One such alternative fuel
is biodiesel which is biodegradable, renewable, non-
toxic and has lower emissions. Biodiesel is generally
produced using oilseeds such as sunflower, soybean,
Company: Bhooma Energy Ventures
Institute: IIT Guwahati
Project: Pilot scale facility for biodiesel production using waste rubber seed as raw material
CASE STUDY 15
rapeseed, linseed, cotton and canola; majority of which
are edible in nature and have widespread commercial
value. India being an importer of edible oils, use of
these for biodiesel production is unaffordable and
illogical.
To overcome this, this project aimed at biodiesel
production from non-edible rubber seed oil which
is abundantly available in the north-east region. The
north-eastern states have emerged as significant
rubber suppliers in India. Rubber is grown across
the states of Assam, Tripura, Meghalaya, Mizoram,
Manipur, Nagaland and Arunachal Pradesh. Rubber
seed and rubber seed oil, by-products of the rubber
industry, are traditionally considered waste apart
from some trivial uses such as manufacture of inferior
quality laundry soap, paints and varnishes, grease,
tanning of leather etc. Most of this oil is discarded
due to lack of useful applications.
IIT Guwahati’s Department of Chemical Energy had
been doing research on the possibility of creating bio-
fuel using rubber seed oil and had made significant
advancements in this regard. It had established the
technology to produce biodiesel from rubber seed
but needed expertise to scale up the production
technology for mass usage and commercialization.
It was envisaged that a successful validation and
application of this technology would have widespread
benefits and would help in the expansion of rubber
processing industry in the north-eastern region
resulting in livelihood generation and supplementing
incomes of rubber growers.
Bhooma Energy Ventures was working in the field of
biodiesel for over five years, with a 25 mt biodiesel
plant commissioned in Bangalore in 2011. It was
looking for commercially viable technology to use
waste rubber seeds for biodiesel production. When it

42
came to know of the facility available at IIT Guwahati
it proposed supporting the project by providing
minimum 25 per cent of the total budget requirement
of Rs 65 lakh as per the norms of Uchchatar Avishkar
Yojana1
(UAY), along with offering to take care of the
supply chain management. The company also assured
buy-back guarantee of the produced biodiesel and all
possible technological expertise as required.
IIT Guwahati agreed to sign an agreement regarding
the project with Bhooma Energy Ventures and both
also decided to apply for UAY for funding support.
The concerned ministry -The Ministry of New and
Renewable Energy (MNRE) - was also approached
which agreed to fund 25 per cent of the project cost.
After in-depth discussions, it was decided that at
initial stages a cost efficiency survey for raw material
supply from different locations of north-east will
be done. Subsequently, the developed technology
was to be used to produce 1 mt biodiesel from the
established lab-based technology. The lubricity of
different biodiesel samples was to be measured.
Thermal and oxidation stability, cold flow properties
and other fuel properties of different alkyl esters were
to be determined. The effects of fatty acid profile and
alcohol type on the lubricity performance of biodiesel
were to be studied. Engine performance and emission
profile study of different biodiesel samples would be
carried out. At the end, customer and business models
would be developed for sustainable production.
The MOU regarding this project was awarded funding
support under UAY and the MOU was also exchanged
at Rastrapati Bhavan during the CII Session for
Industry-Academia Linkages in the presence of the
Hon’ble President of India, Union HRD Minister and
other dignitaries on 16 November 2016.
1
Uchchatar Avishkar Yojana is a funding scheme of the Ministry of Human Resource Development for industry-sponsored,
outcome-oriented research projects. It is applicable to Indian Institutes of Technology only and industry partnership is an
essential pre condition. The funding pattern under this scheme is 25 + 25 + 50 where 25 per cent of the project cost comes
from partner company, 25 per cent from relevant ministry and 50 per cent from MHRD.
Present status
The tendering process has been completed; the plant
is already set up and will be functional soon. The
interaction and collaborative development of the pilot
plant would help develop the production technology,
expertise, intellectual property and a facility for self-
sustained internal source of renewable energy.
Summary of Benefits
• First of its kind 1 mt biodiesel plant from waste
raw rubber seed
• Commercial level scaling up of indigenously
developed lab technology
• Novel initiative targeting uninterrupted power
supply in remote locations of north-eastern India
• Far-reaching environmental benefits
• Strengthening of laboratory and research facility
of both IIT Guwahati and Bhooma Energy
Ventures.
Image Courtesy: http://123rf.com

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conducive to the development of India, partnering industry, Government, and civil
society, through advisory and consultative processes.
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