The document summarizes Cartic Ramakrishnan's dissertation on extracting semantic metadata from text to facilitate knowledge discovery in biomedicine. It defines knowledge discovery as opportunistic search over an ill-defined space leading to surprising but useful knowledge. It discusses using ontologies and text mining to extract semantic relationships from unstructured text and represent them as structured semantic metadata to enable knowledge exploration and discovery. It presents preliminary work on automating some of Swanson's biomedical discoveries by extracting relationships between concepts from parsed sentences in publications.