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This document lists several sexually transmitted infections including HIV/AIDS, HPV, syphilis, gonorrhea, chancro blando, chlamydia, genital herpes, lymphogranuloma venereum, pediculosis, and identifies it as being from the 6th semester, group 7, year 2011.

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Introduction: malignant syphilis is an uncommon form of secondary syphilis.This presentation usually occurs in immunocompromised patients, especially in those ones infected by human immunodeficiency virus (HIV). However, it is known that it might exceptionally affect individuals with normal immune response. Case report: in this manuscript, we report a case with ocular involvement in a male immunocompetent patient. He had extended skin lesions and conjunctival hyperemia on the right eye. After the laboratorial investigation we confirmed syphilis and excluded human immunodeficiency virus (HIV) infection. Considering he had uveitis, the case was conducted as neurosyphilis.and the treatment was made with Ceftriaxone, followed by excellent clinical response. Conclusion: given the increasing number of cases of syphilis, in patients with polymorphic skin lesions associated with systemic symptoms, it is important to exclude immunosuppression and even in immunocompetent.subjects this condition should always be a differential diagnosis. Keywords: Malignant Syphilis; Immunocompetent; Uveitis

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