This document discusses caring for dying patients. It outlines that junior doctors are often required to care for dying patients. Proper care involves early recognition that a patient is dying, continuous assessment of their needs, anticipating and promptly managing symptoms, and ensuring the patient's and family's wishes are addressed. Key goals are keeping the patient free from pain, respiratory secretions, nausea and breathlessness and providing psychological and spiritual support for the patient and family.
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the ot nursing is an essential concept that every student nurse must have an adequate knowledge in order to counteract the issues related to OT nursing.
Gowning and gloving technique Presented By Mohammed Haroon Rashid At Florence...Haroon Rashid
This Topic presented by Mohammed Haroon Rashid From Basic B.Sc Nursing Final Year students in Florence College of nursing Limtara dhamtari. This topic presented on workshop on the date 13 sep 2019.
the ot nursing is an essential concept that every student nurse must have an adequate knowledge in order to counteract the issues related to OT nursing.
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Therapeutic environment can be defined as the total of all external conditions and influences affecting an individual in the illness situation.Infection prevention in the operating room is achieved through prudent use of aseptic techniques in order to prevent contamination of the open wound.
Isolate the operating site from the surrounding unsterile physical environment.
Create and maintain a sterile field in which surgery can be performed safely.
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Types of Articles and Care of Articles Ujjwal Patel
This presentation is on topic of Types of Articles, Care of Articles and introduction to ward inventory and indent. Nursing Foundation is the core subject of First Year B.Sc. Nursing and this topic is important for the theory and the practical. This presentation briefs the detailed care of article used in hospital.
Therapeutic environment can be defined as the total of all external conditions and influences affecting an individual in the illness situation.Infection prevention in the operating room is achieved through prudent use of aseptic techniques in order to prevent contamination of the open wound.
Isolate the operating site from the surrounding unsterile physical environment.
Create and maintain a sterile field in which surgery can be performed safely.
Prevention of Accidents in An Operation Theatre-NURSINGMariaKuriakose5
This is a PowerPoint made to explain various hazards in an operation theater and with its preventive measures.This will hepl the nursing students to go through the important points rather than going into deep studies.
CODE OF ETHICS: The guiding principle in nursing
code are the direction of conduct , understanding of what is right and wrong while providing care in the hospital and community settings.The ICN code of ethics are the milestone to establish nursing as a profession.
A complete study material for a good presentation for the subject advance nursing practice in MSc Nursing level. It is presented by Angelina samuel lal.
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Year 3 work for a Nigerian nursing student end of life care a PowerPoint slide for nursing school. A university nursing student. Year 3 work for a Nigerian nursing student end of life care a PowerPoint slide for nursing school. A university nursing student. Year 3 work for a Nigerian nursing student end of life care a PowerPoint slide for nursing school. A university nursing student. Year 3 work for a Nigerian nursing student end of life care a PowerPoint slide for nursing school. A university nursing student.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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The prostate is an exocrine gland of the male mammalian reproductive system
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- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. “Caring for a Dying
Patient”
‘Am I Going To Die?’
Dr Yassir NourEldaim
Consultant of Anaesthesia&ICU
2. Introduction
• Every year, more than half a million people die
in the United Kingdom, and over half of these
deaths occur in hospital.
• Junior doctors are often required to care for
dying patients
• Early recognition of dying facilitates meeting
patients’ and relatives’ preferences for end of
life care
•Communication is the cornerstone of good end
of life care
•The principles of end of life prescribing are: to
stop non-essential drugs; convert essential
drugs to the subcutaneous route; and use
anticipatory prescribing
3. Cont: Introduction
•Terminal care is not just cancer care
but other relevant diseases include:
1. Heart failure.
2. Respiratory failure.
3. Chronic renal failure.
4. Hepatic failure.
5. Certain neurological diseases such as
multiple sclerosis and motor neurone
disease,.
6. AIDS.
4. keys
•The key to managing and supporting
the dying patient involves:
1. Identifying that the patient is dying.
2. Continuous assessment of symptoms
& psychological/spiritual needs.
3. Anticipating likely problems before
they arise so that treatments are
readily available.
4. Appropriate & prompt management
of symptoms
5. Strategic goals for the dying
patient
Both the patient’s/family’s awareness &
understanding of diagnosis of dying is
communicated and documented.
Patient is assessed and a care plan is
developed in line with the
patient’s/family’s wishes.
6. Clinical goals for the dying
patient
1. Current medication assessed & non-essential
medicines discontinued.
2. PRN subcut meds/fluids written up as
appropriate.
3. Inappropriate interventions discontinued e.g.
blood tests, BP monitoring.
4. Cardiac defibrillators (ICDs) deactivated in
consultation with cardiologist.
5. DNAR order completed.
6. Organ donation considered
7. Ongoing assessment goals for the
dying patient
1. Patient is free from pain, agitation, excessive
respiratory tract secretions &
nausea/vomiting,severe breathlessness.
2. Pressure care - if death is imminent, reposition
for comfort only – consider pressure relieving
mattress.
3. Bowel care – patient is free from bowel
problems causing distress.
4. Urinary status – patient has appropriate aids.
5. Eyes, mouth & lips clean & moist - consider
family involvement in these tasks, if
appropriate
8. Cont:Ongoing assessment goals for
the dying patient
1. Emotional & psychological care– patient and
family have appropriate support
2. Spiritual, religious and cultural support –
needs are assessed and supported
3. GP and community team informed of the
patient’s condition
4. Goals to support the family as the patient
nears death
5. Next-of-kin / significant others identified &
contact details recorded.
6. Family prepared as far as possible for the
patient’s death
10. Pronouncing Death
•It is important to pronounce and
confirm death in a professional yet
compassionate manner, knowing that
the family will remember acutely this
time, your words, and the tone of your
voice.
11. Death Certification
•A death certificate is available from the local
registrar of Births Deaths and Marriages by
providing the following details to register the
death:
1. Full name and surname of the deceased
2. Gender, marital status, occupation and date of
birth or age of the deceased.
3. Date and place of death.
4. If deceased was married, the occupation of their
spouse, or deceased spouse if widowed.
5. If deceased was a child, the occupation of the
father or, if the parents were not married the
occupation of the mother.
6. Death Notification Form of the Cause of Death.
Editor's Notes
'Next Of Kin: A person's closest living blood relative.