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Cardiac Output Measurement
Ms.P.Nishanthi KIT-CBE
Introduction to Cardiac Output
● Cardiac output is the product of heart rate (HR) and stroke volume
(SV) and is measured in liters per minute.
● HR is most commonly defined as the number of times the heart
beats in one minute.
● SV is the volume of blood ejected during ventricular contraction or
for each stroke of the heart.
Importance of Cardiac Output Measurement
● The management of hemodynamically unstable patients requires
an assessment of the cardiac output (CO) and the patients'
intravascular volume status (cardiac preload).
● In most instances the absolute value of the CO is less important
than the response of the CO to a therapeutic intervention.
Methods for Cardiac Output Measurement
● Thermodilution
● Doppler Ultrasound
● Echocardiography
● Fick Principle
● Impedance Cardiography
● Arterial Pressure Waveform Analysis
Thermodilution Method
● The thermodilution method involves injection of a definite amount
of heat into the bloodstream, and the corresponding downstream
temperature change is recorded.
● A cold fluid is often used as an indicator in the thermodilution
method, because cold fluid is less harmful to the blood and tissue
than a hot fluid.
Doppler Ultrasound
● A Doppler ultrasound is a noninvasive test that can be used to
estimate the blood flow through your blood vessels by bouncing
high-frequency sound waves (ultrasound) off circulating red blood
cells.
● A regular ultrasound uses sound waves to produce images, but
can't show blood flow.
Echocardiography
● An echocardiogram uses sound waves to create pictures of the
heart. This common test can show blood flow through the heart and
heart valves.
● Your health care provider can use the pictures from the test to find
heart disease and other heart conditions.
Fick Principle
● The Fick principle states that uptake of oxygen in blood by the lung
(mL/min) is equal to the product of the AVO2 diff of the oxygen and
the blood flow to the lung.
● Therefore, if the arterial O2 content, venous O2 content and oxygen
consumption are measured, the CO can then be calculated.
Impedance Cardiography
● Impedance cardiography and bioreactance are two methods of
quantifying cardiac function without invasive monitoring.
● Both methods use electrophysiology to measure how changes in
aortic blood volume and flow influence transmission of a known
electrical current across the thorax.
Arterial Pressure Waveform Analysis
● The arterial waveform reflects the change in pressure over time, or
dP/dt, and thus the slope of the upstroke reflects this.
● Generally speaking, the steeper the slope, the quicker the rise, the
greater the dP/ dt, and the stronger the contractile forces appear.
Clinical Applications
● Management of heart failure
● Assessment of shock
● Intraoperative monitoring
● Intensive care settings
Factors Affecting Cardiac Output
● Management of heart failure
● Assessment of shock
● Intraoperative monitoring
● Intensive care settings

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Cardiac output measurement.pptx

  • 2. Introduction to Cardiac Output ● Cardiac output is the product of heart rate (HR) and stroke volume (SV) and is measured in liters per minute. ● HR is most commonly defined as the number of times the heart beats in one minute. ● SV is the volume of blood ejected during ventricular contraction or for each stroke of the heart.
  • 3. Importance of Cardiac Output Measurement ● The management of hemodynamically unstable patients requires an assessment of the cardiac output (CO) and the patients' intravascular volume status (cardiac preload). ● In most instances the absolute value of the CO is less important than the response of the CO to a therapeutic intervention.
  • 4. Methods for Cardiac Output Measurement ● Thermodilution ● Doppler Ultrasound ● Echocardiography ● Fick Principle ● Impedance Cardiography ● Arterial Pressure Waveform Analysis
  • 5. Thermodilution Method ● The thermodilution method involves injection of a definite amount of heat into the bloodstream, and the corresponding downstream temperature change is recorded. ● A cold fluid is often used as an indicator in the thermodilution method, because cold fluid is less harmful to the blood and tissue than a hot fluid.
  • 6. Doppler Ultrasound ● A Doppler ultrasound is a noninvasive test that can be used to estimate the blood flow through your blood vessels by bouncing high-frequency sound waves (ultrasound) off circulating red blood cells. ● A regular ultrasound uses sound waves to produce images, but can't show blood flow.
  • 7. Echocardiography ● An echocardiogram uses sound waves to create pictures of the heart. This common test can show blood flow through the heart and heart valves. ● Your health care provider can use the pictures from the test to find heart disease and other heart conditions.
  • 8. Fick Principle ● The Fick principle states that uptake of oxygen in blood by the lung (mL/min) is equal to the product of the AVO2 diff of the oxygen and the blood flow to the lung. ● Therefore, if the arterial O2 content, venous O2 content and oxygen consumption are measured, the CO can then be calculated.
  • 9. Impedance Cardiography ● Impedance cardiography and bioreactance are two methods of quantifying cardiac function without invasive monitoring. ● Both methods use electrophysiology to measure how changes in aortic blood volume and flow influence transmission of a known electrical current across the thorax.
  • 10. Arterial Pressure Waveform Analysis ● The arterial waveform reflects the change in pressure over time, or dP/dt, and thus the slope of the upstroke reflects this. ● Generally speaking, the steeper the slope, the quicker the rise, the greater the dP/ dt, and the stronger the contractile forces appear.
  • 11. Clinical Applications ● Management of heart failure ● Assessment of shock ● Intraoperative monitoring ● Intensive care settings
  • 12. Factors Affecting Cardiac Output ● Management of heart failure ● Assessment of shock ● Intraoperative monitoring ● Intensive care settings