Cannabis contains many compounds beyond just THC that have therapeutic potential. Different cannabinoids like CBD, CBG, CBC, and THCV, as well as terpenes, may help treat conditions like epilepsy, cancer, inflammation and more. While THC is best known, exploring other varieties of the cannabis plant could lead to new medical discoveries, as combinations of compounds may produce synergistic effects or enhance each other in ways that single compounds alone do not. The full therapeutic potential of cannabis and its components is still being revealed.

1. Cannabis is More Than THC JahanMarcu 4/22/2011

2. Where did Cannabis come from? Hillig KW. Genetic evidence for speciation in Cannabis (Cannabaceae).Genetic Resources and Crop Evolution. 2005;52:161-80.

3. A little more history… Shou-zhong, Y. 1997. The divine farmer's materiamedica: A translation of the ShenNong Ben Cao Jing. Boulder, CO: Blue Poppy Press. Perfumed Garden, as translated by Sir Richard Burton, Park St. Press: Rochester, VT, 1992, p. 26.

7. Cultivar: clonal propagation

9. Genetic testing can distinguish between a strain and a cultivar

10. Example, Trainwreck, Bubakush, etc are cultivars from a THC variety or strain

13. CBG plants found in Europe (de Meijer et al.2005).

14. Propyl Cannabis Strains (CBGV, THCV,CBDV)

16. Phytocannabinoids: The Future CBD: rheumatoid arthritis, inflammatory bowel disease (TNF-α inhibition) THCV: metabolic syndrome (CB1 antagonism), epilepsy (CB1-mediated) CBDV: epilepsy, bone formation/healing CBG: prostatic cancer (TRPM8 antagonism), anxiety (AEA reuptake inhibition?), antibiotic (MRSA et al.) β-Caryophyllene: selective CB2 agonist Courtesy of E. Russo.

17. Plant Wisdom: Synergy and Enhancement Anticancer THC & CBD (Marcu et al. 2010) Efficiency THC & CBC (De Long et al. 2010)

18. THC and Terpenoids May modulate activity in several ways: CB receptor interactions Increase THC affinity Remodel G proteins Changes to BBB; alters pharmokinetics “Generally, inhaled terpenoids cause sedation.” -McPartland

19. Major Components Beta-Caryophyllene Caryophyllene Oxide Limonene Linalool Myrcene Alpha-humulene Nerolidol

20. Conclusion A THC variety by any other name… The THC variety of Cannabis is NOT the only type of Cannabis Many new varieties of medicine await discovery Cannabis is not the only source of cannabinoids Different ingredients can enhance and inhibit different effects Freedomisgreen.com Cannabination.com