This document provides a summary of a presentation on translating the science on marijuana into effective public health messages. The presentation aimed to understand the latest science on marijuana use and how to frame prevention messages. It identifies concerns related to marijuana use and legalization such as addiction, impaired driving, and negative impacts on adolescent brain development and academic achievement. The presentation argues for using strong evidence from research to change the discussion on marijuana from complicated to simple and from negative to positive. It provides sample messages focused on how marijuana use could negatively impact things people care about like education, employment, and highway safety.