This document provides tips for authors to promote their published scientific articles in order to maximize visibility and impact. It recommends optimizing article content for search engines, using features like graphical abstracts and AudioSlides. Authors should share their work on social media, create an online profile on sites like LinkedIn and ORCID, start a blog, and work with their institution's press office to promote their research to the media. The publisher, Elsevier, will also promote selected articles through press releases and newsletters sent to journalists.
Microblogging for Enhancing the Research AccessibilityNader Ale Ebrahim
There are statistically significant associations between higher citations for articles and the use of various social networking sites such as Twitter, Facebook, blogs and forums. Twitter is a microblogging tool and social media site created in 2006 that gives you a chance to share quick thoughts using not more than 140 characters in a post. It’s a great way to share your current research, publications and links to achieve maximum publicity. Twitter assist you to stay current with the literature and new developments in your field of interest. Proper tools allow the researchers to increase the research impact and citations. This presentation will provide various techniques on how microblogging improving your research impact and visibility.
Microblogging for Enhancing the Research AccessibilityNader Ale Ebrahim
There are statistically significant associations between higher citations for articles and the use of various social networking sites such as Twitter, Facebook, blogs and forums. Twitter is a microblogging tool and social media site created in 2006 that gives you a chance to share quick thoughts using not more than 140 characters in a post. It’s a great way to share your current research, publications and links to achieve maximum publicity. Twitter assist you to stay current with the literature and new developments in your field of interest. Proper tools allow the researchers to increase the research impact and citations. This presentation will provide various techniques on how microblogging improving your research impact and visibility.
Beyond the Journal Impact Factor: Altmetrics; New Ways of Measuring Impactsbeas1
A powerpoint presentation given at Portland State University Library as part of the Library's workshop series for faculty. Download the file to see the notes for each slide.
There are currently approximately 28,000 journals publishing 1.5 million papers annually. Although the majority of new journals are legitimate, the credentials of some are questionable. Such journals and publishers are referred to as 'predatory'. They commonly send spam emails to potential authors, solicit submissions and request payment of article processing charges, but lack academic rigour or credibility. This presentation will look at examples of publishers, publications and provide practical tips to identify and avoid predatory publishers.
Beyond the Journal Impact Factor: Altmetrics; New Ways of Measuring Impactsbeas1
A powerpoint presentation given at Portland State University Library as part of the Library's workshop series for faculty. Download the file to see the notes for each slide.
There are currently approximately 28,000 journals publishing 1.5 million papers annually. Although the majority of new journals are legitimate, the credentials of some are questionable. Such journals and publishers are referred to as 'predatory'. They commonly send spam emails to potential authors, solicit submissions and request payment of article processing charges, but lack academic rigour or credibility. This presentation will look at examples of publishers, publications and provide practical tips to identify and avoid predatory publishers.
Professional Digital Presence for the Librarian Reseachermputerba
Good Day,
Take the survey https://bit.ly/2ZlJvkR
My colleagues Heather Alexander, Dominican College, and Hua Sun, Shandong University of Arts, and I are researching the development of librarians as professionals. Part of this research comes in the shape of a survey found at https://bit.ly/2ZlJvkR. The study looks at one aspect of this research, the promotion of librarians as researchers.
Generally speaking, librarians conduct research as part of their work. Usually, this research involves day to day tasks such as the gathering usage statistics for ILL, databases, and the physical library. These are important within the institution. At other times the information gathered by librarians has practical implications for the profession as a whole and are shared in publications or conference presentations.
As part of our research, we want to know if and with what tools librarians promote their research as professionals. In particular, we are looking at the use of social media to create a professional digital presence.
Please help us in this study by taking the survey at https://bit.ly/2ZlJvkR . The survey takes less than 10 minutes. We are doing this solely for scholarly purposes.
If you would like to review the sites discussed in the survey, please see the presentation at https://bit.ly/2JxSfiR .
Thank you,
Mark Puterbaugh
Reference Librarian PT
mark.puterbaugh@rutgers.edu
ORCiD: https://orcid.org/0000-0002-6371-5439
Institute for Global Environmental Strategies (IGES) - Mendeley Institution E...Nurhazman Abdul Aziz
The Institute for Global Environmental Strategies (IGES) was established in March 1998 under an initiative of the Japanese government and with the support of Kanagawa Prefecture based on the "Charter for the Establishment of the Institute for Global Environmental Strategies".
Their Mendeley Institution Edition can be accessed via http://www.mendeley.com/groups/3790841/institute-for-global-environmental-strategies-iges/
Download Mendeley for free at http://mendeley.com
Academic social networking allows you to connect with other researchers in your field, share your publications and datasets, get feedback on your non-peer-reviewed work, and to stay current with news and events in your field of interest. It gives you another place to establish your name and research and perhaps even collaborate with others. The academic, social networking, making your work more widely discoverable and easily available. LinkedIn (launched in 2003) is currently the third most popular social network in terms of unique monthly visitors, right behind Facebook and Twitter. The LinkedIn is primarily centered around careers, and it enables users to connect and share content with other professionals. In addition, it is an online CV and as a place to share your publications.
Researchers want to publish in journals that can increase the visibility and impact of their research. Increasing a journal’s visibility in the academic world in order to improve the journal’s impact and receive citations is essential. This webinar presents the fifteen strategies for journal publishers to increase the journal’s article citations without “gaming” the system. Nader, who has developed the “Research Tools” Mind Map will get you familiar with a few simple tools you need in order to grow your journal’s visibility and impact factor which can make a significant difference for many journals.
Introduction to “Research Tools”: Tools for Collecting, Writing, Publishing, ...Nader Ale Ebrahim
“Research Tools” enable researchers to collect, organize, analyze, visualize and publicized research outputs. I have collected over 700 tools that enable researchers to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. “Research Tools” consists of a hierarchical set of nodes. It has four main nodes: (1) Searching the literature, (2) Writing a paper, (3) Targeting suitable journals, and (4) Enhancing visibility and impact of the research. This presentation will provide an overview to the most important tools from searching literature to disseminating researcher outputs. The e-skills learned from the workshop are useful across various research disciplines and research institutions.
Mendeley is:
1. a reference manager allowing you to manage, read, share, annotate and cite your research papers.
2. a social & academic collaboration network with 6 Million users to connect like-minded researchers & discover research trends and statistics
3. a crowdsourced database with a unique layer of social research information and an Open API
Seminario de autores Elsevier en la Universidad de Zaragoza “How to Write Great Papers: From title to references, from submission to publication” - June 4th, 2015 - Salón de Actos - Biblioteca de Humanidades "María Moliner" Zaragoza.
Presentación de Edward Wedel-Larsen: "Mendeley. Your research anywhere"
Scholarly blogs help researchers to establish expertise, forge new intellectual bonds in their discipline, and give them a place to test out new ideas and promote their research. Blog services provide your research seen by more non-academics than your peer reviewed papers will ever be. The importance of this is not to be dismissed. Blogs are a vital tool for academics to publicly communicate about research developments and findings. Academics can also gain feedback from other peers, as well as expand their networks and enhance research visibility. This presentation will provide guidelines on blogging as a tool for increasing the article visibility and citations. Increased visibility online helps your offline recognition.
Congratulation, you published a paper. Has anyone read it? or Cited it? Citation tracking is used to discover how many times a particular article has been cited by other articles. Citation counts are not perfect. They are influenced by a number of factors. Review articles are sometimes more often cited than their quality would warrant. Poor quality papers can be cited while being criticized or refuted. In this workshop, I will explain about the advantages of "Citation Tracking" and introduced some “Research Tools” for improving the research impact and citations by “Tracking Citations”.
With the advent of Web 2.0 into research, researchers conduct research is changing, as are the resources and infrastructure which increased power their work. In the past e-Science and cyber-infrastructure was dominated by epic science using brave infrastructures. But these days we can find the researchers across all disciplines exploiting new technologies to make new research. More user focused activity is illustrated on the web as a distributed application platform, offering easy access to computational resources jointly with social networking to impart the pieces and practice of digital research. In this paper, it illustrates the tools and techniques of web 2.0 application for conducting research.
E-PIC Elsevier Product Insights for Customers - Available for Administrators ...Genevieve Musasa
- Elsevier Product Insights for Customers offers you a free and unique view on your organization's engagement with Elsevier's research content and tools.
- The dashboard is meant for administrators and librarians who recognize the role of great content and tools in a successful research strategy. It is the result of Elsevier's enduring focus on customer value and transparency.
- The Dashboard is designed to provide an easy view on the engagement of your researchers with Elsevier products: content as well as information tools.
- The current product is under development and we will continuously add more data points and insights, so please stay up to date with developments.
ScienceOpen: Rethinking Peer Review / Young Academy of ScotlandScienceOpen
Hosted by the RSE Young Academy of Scotland Open Data Working Group
The scholarly publishing paradigm is changing – Open Access, altmetrics, data-mining are increasingly setting new standards. A recent Royal Society conference on “The Future of Scholarly Scientific Communication” called in particular for sweeping reforms to the current system of peer review. The new platform ScienceOpen has taken up the challenge. In order to put the evaluation of research back in the hands of researchers, we are experimenting with new forms of author-mediated pre-publication peer review. Published articles are open for transparent post-publication peer review and versioning to reflect feedback as the scientific community reads, works with, attempts to reproduce and builds on the results. The essential efforts of peer reviewers in this process are recognized with a citable CrossRef DOI for their report. ScienceOpen goes further to extend this open research evaluation process to over 1.5 million aggregated Open Access publications. We are taking advantage of this transitional moment to rethink how scientific communication, and particularly peer review could function in the future, because we believe that scholarly publishing is not an end in itself, but the beginning of a dialogue to move the whole scientific venture forward.
How To Write And Publish the Engineering Research Paper In International Jour...PhD Assistance
Being printed in international journals demonstrates a sincere desire to showcase one’s ability to the general public. Even an internet journal can boost an author’s reputation. Of course, getting published in reputable resources isn’t easy, but if you succeed, you’ll have a myriad of possibilities, such as a better job, sponsorship, and larger payments. Phdassistance offer services to help you Publish an Engineering Research Paper, Publish an Engineering Help and Manuscript Journals publish.
To Learn More: https://bit.ly/3HPU3PK
For Enquiry:
India: +91 91769 66446
UK: +44 7537144372
Email: info@phdassistance.com
I. Introduction to scholarly publishing
II. How to get published? Practical Advices
III. Structuring your article
IV. The reviewing process
V. How not to Publish
VI. Get noticed
Improve Research Visibility by Establishing an Academic BlogNader Ale Ebrahim
Academic blogs help researchers to establish expertise, forge new intellectual bonds in their discipline, and give them a place to test out new ideas and promote their research. Blog services provide your research seen by more non-academics than your peer reviewed papers will ever be. The importance of Academic Blog is not to be dismissed. Blogs are a vital tool for academics to publicly communicate about research developments and findings. Academics can also gain feedback from other peers, as well as expand their networks and enhance research visibility and impact. This presentation will provide guidelines on Academic Blogging as a tool for increasing the article visibility and citations. Increased visibility online helps your offline recognition as well.
Mendeley Institutional Edition - Universiti Kebangasaan MalaysiaNurhazman Abdul Aziz
Universiti Kebangsaan Malaysia is one of five research universities in the country. Their MIE group can be view at http://www.mendeley.com/groups/3944951/universiti-kebangsaan-malaysia/.
Ameliorative potential of the quercetin on lead-induced testicular damage mor...Prof. Hesham N. Mustafa
Background
Quercetin, a naturally occurring flavonoid known for its potent antioxidant properties, has been investigated for its potential in counteracting the harmful effects of lead (Pb) toxicity, which induces apoptosis and oxidative damage in various human tissues. This study aims to assess the reparative effects of quercetin on lead-induced testicular damage.
Methods
Four groups, each comprising ten adult male albino rats, were randomly assigned as follows: Quercetin group, Pb group, Pb + Quercetin group, and control group. All treatments were administered orally via gavage daily for a duration of 30 days. Evaluation of sex hormone levels (serum testosterone, FSH, and LH), cytokines and inflammatory mediators (IL-1β, TNF-α, MCP-1), lead concentration, oxidative and antioxidant stress markers (superoxide anion [O2−], MDA, SOD, CAT, GSH), and sperm characteristics were carried out.
Results
The results demonstrated a significant decline in sex hormones and antioxidants, accompanied by an increase in lead concentrations, cytokines, inflammatory mediators, and oxidative stress indicators (O2−, MDA), while SOD, CAT, and GSH levels were reduced. The Pb-intoxicated group exhibited a substantial increase in dead and abnormal sperm, along with significant reductions in sperm concentration and motility. Morphometrically, a marked decrease was observed in spermatogonia, primary spermatocytes, spermatids, and sertoli cells per seminiferous tubule, as well as epithelial height. Furthermore, coadministration of quercetin exhibited notable benefits. It significantly elevated testosterone levels (P < 0.001), testicular SOD, CAT, and GSH activities, while decreasing MDA levels (P < 0.001). Quercetin also mitigated the deleterious effects of lead toxicity on sperm parameters and restored morphometric variations, including epithelial height.
Conclusions
Quercetin supplementation alongside lead exposure showed a potential for ameliorating degenerative changes caused by lead toxicity in the testicles. This cotreatment effectively reduced oxidative stress, cytokine levels, inflammatory mediators, and restored biochemical alterations, thereby improving morphometric parameters.
The pattern of branching and intercommunications of the musculocutaneous nerv...Prof. Hesham N. Mustafa
Background:
The aim of the present work was to provide evidence about the anatomical variations as regard the origin, distribution, and branching pattern of the musculocutaneous nerve (MCN).
Materials and methods:
Brachial plexus was dissected in 40 upper limbs of 20 male adult cadavers. The pattern of the musculocutaneous nerve was photographed by a digital camera.
Results:
The location and length of the nerve branches between left and right arms were recorded and statistically analyzed. In (90%) of specimens the MCN originates from the lateral cord of the brachial plexus, in (5%) it arose from the median nerve (MN), while in the remaining (5%) specimen, it was absent. The musculocutaneous nerve pierced the coracobrachialis muscle in 90% of specimens, and in the remaining (10%) did not pierce it. The motor branches to biceps brachii muscle were categorized into: Type 1 (90%): one branch that divides to supply the two heads of biceps; Type 2 (5%): double branches, innervating each head of biceps separately. The motor branches to brachialis muscle were categorized into: Type 1 (82.9%): one branch; Type 2 (14.2%): double branches and Type 3 (2.9%): three branches that innervating brachialis muscle. Communications between the MCN and the MN were observed in 35% of specimens.
Conclusions:
The knowledge of the common and uncommon musculocutaneous nerve variations is important especially to the surgeons for carrying out surgical procedures in axilla and arm.
Morphohistometric analysis of the effects of Coriandrum sativum on cortical a...Prof. Hesham N. Mustafa
Objective: Natural compounds can act as metal chelators and oxygen free radical scavengers, which allows them to be used as bioactive antagonists to heavy metals neurotoxicity. The aim of the study to analyze the morphometric effects of Coriandrum sativum (C. sativum) on lead-induced neurotoxicity.
Materials and Methods: Forty Sprague-Dawley albino rats were divided into four equal groups (ten in each group): control group; coriander group: received aqueous C. sativum extracts (600 mg/kg BW for 60 days orally); lead (Pb) group: received a daily dose of lead acetate (Pb) (10 mg/kg BW for 60 days orally); Pb+ coriandrum group: received: aqueous C. sativum extract (600 mg/kg BW) prior to 10 mg/kg BW of Pb. The following parameters malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were measured. Layers thickness and nuclei density were analyzed.
Results: Lead levels in blood and tissues were decreased significantly in the Pb group and those findings were corrected significantly (p=0.001) with C. sativum addition. Data exhibited an increase in oxidative stress marker MDA and a decrease in antioxidant enzymes activities (SOD, CAT, and GPx) significantly in the Pb group and those effects were reversed significantly (p=0.001) by C. sativum administration. The cerebellar cortex and all layers of the somatosensory cortex thickness and nuclei density were diminished significantly in the Pb group. The morphometrical measurements were corrected significantly (p=0.001) by C. sativum.
Conclusion: From the findings of the current study, Pb caused noticeable structural and functional variations in the cerebellar cortex and somatosensory cortex. C. sativum corrected these parameters as it possesses chelating and antioxidant potentials.
Background:
The anterolateral ligament (ALL) is a true well-defined ligament in the knee first described in 1879 by Segond. After the work of Claes et al., several studies were conducted about biomechanics and its role in stability of the knee. The anatomical existence of the ALL has been studied by and various radiographic diagnostic modalities and in cadavers. It originates from lateral femoral epicondyle and is inserted between Gerdy’s tubercle and the fibular head. There has been controversy about the existence of ALL in pediatric patients. The aim of this work was to confirm the presence of ALL in pediatric patients by using MRI.
Materials and Methods:
We reviewed the knee MRI scans of 100 pediatric patients (ages between one and 12 yr) who had no knee injury or congenital deformity and had been evaluated by an expert radiologist.
Results:
The ALL was detected in 90% of the pediatric patients with the use of MRI.
Conclusions:
The main finding of this study was that ALL can be seen in pediatric patients using MRI. Despite numerous studies, additional research is needed to further define the role of the ALL in knee function.
Level of Evidence:
Level IV.
Protective effect of garlic extract against maternal and fetal cerebellar dam...Prof. Hesham N. Mustafa
Background: In spite of its industrial usefulness and varied daily uses, lead (Pb) pollution is a widespread ecological problem that faces the humans in the 21th century. Pb was found to produces a wide range of toxic effects including neurotoxicity especially to the developing and young offspring. Recently, the utilisation of herbal plants has received a significant attention where there has been rising awareness in their therapeutic use; among these is the garlic. In light of the above, the current study is designed experimentally in female pregnant rats in order to investigate the beneficial role of garlic extract in the protection from the maternal and foetal cerebellar damage produced by administration of different doses of Pb during pregnancy.
Materials and methods: Positively pregnant female rats were divided into five groups; one control group, two Pb-treated groups (exposed to 160 and 320 mg/kg b.w. of Pb, respectively) and two groups treated with both Pb and garlic (exposed to Pb as previous groups together with 250 mg/kg b.w./day of garlic extract). Treatments started from day 1 to day 20 of pregnancy, where the mother rats of different experimental groups were sacrificed to obtain the foetuses. Pb level in the maternal and foetal blood and cerebellum was estimated by spectrophotometry. Specimens of the cerebellum of different mother and foetal groups were processed to histological and immunohistochemical staining for microscopic examination.
Results: The results showed that administration of Pb to pregnant rats resulted in a dose-dependent toxicity for both mothers and foetuses in the form of decrease in maternal weight gain, placental and foetal weights, brain weight and diminished foetal growth parameters, which were prominent in rat's group treated with larger dose of Pb. In Pb-treated rats, Pb level in blood and cerebellum was high when compared with the control group. The histopathological examination of the cerebellum of treated dams and foetuses showed marked alterations mainly in the form of Purkinje cell degeneration and lack of development of foetal cerebellum. Co-treatment of garlic extract along with Pb resulted in a significant decrease in Pb levels as compared with those treated with Pb alone with improvement of the histopathological changes.
Conclusions: This study was useful in evaluating the hazardous effects of uncontrolled use of Pb in general and in assessing the developmental and neurotoxicity of foetuses due to exposure during pregnancy in particular. Co-administration of garlic has beneficial effects in amelioration of Pb-induced neurotoxicity and reversing the histopathological changes of the cerebellum of mother rats and foetuses. (Folia Morphol 2018; 77, 1: 1-15).
Keywords: Purkinje cells; garlic; glial fibrillary acidic protein; lead.
Protective role of co q10 or l carnitine on the integrity of the myocardium i...Prof. Hesham N. Mustafa
Doxorubicin (DOX) is a chemotherapeutic agent used for treatment of different cancers and its clinical usage is hindered by the oxidative injury-related cardiotoxicity. This work aims to declare if the harmful effects of DOX on heart can be alleviated with the use of Coenzyme Q10 (CoQ10) or L-carnitine. The study was performed on seventy two female Wistar albino rats divided into six groups, 12 animals each: Control group; DOX group (10mg/kg); CoQ10 group (200mg/kg); L-carnitine group (100mg/kg); DOX+CoQ10 group; DOX+L-carnitine group. CoQ10 and L-carnitine treatment orally started 5days before a single dose of 10mg/kg DOX that injected intraperitoneally (IP) then the treatment continued for 10days. At the end of the study, serum biochemical parameters of cardiac damage, oxidative stress indices, and histopathological changes were investigated. CoQ10 or L-carnitine showed a noticeable effects in improving cardiac functions evidenced reducing serum enzymes as serum interleukin-1 beta (IL-1 β), tumor necrosis factor alpha (TNF-α), leptin, lactate dehydrogenase (LDH), Cardiotrophin-1, Troponin-I and Troponin-T. Also, alleviate oxidative stress, decrease of cardiac Malondialdehyde (MDA), Nitric oxide (NO) and restoring cardiac reduced glutathione levels to normal levels. Both corrected the cardiac alterations histologically and ultrastructurally. With a visible improvements in α-SMA, vimentin and eNOS immunohistochemical markers. CoQ10 or L-carnitine supplementation improves the functional and structural integrity of the myocardium.
Keywords: Cardiotoxicity; CoQ10 and L-carnitine; Dox; Vimentin; eNOS.
One year mortality rate after hip fracture in the western region of saudi ara...Prof. Hesham N. Mustafa
Background:
The mortality rate of elderly patients who sustain a hip fracture is high compared to the general population. Identifying risk factors can help predict patients at risk of hip fracture to reduce the mortality rate. No studies have shown the mortality rate of patients with hip fractures in the western region of Saudi Arabia. Therefore, this study aimed to identify the risk factors associated with the mortality of patients with hip fractures admitted to the King Abdulaziz Hospital and compare the results with other studies.
Methods:
The mortality rate (within 1 yr or less) in 177 patients over the age of 60 yr who were admitted to the university hospital between July, 2007, and September, 2012, with hip fractures was retrospectively studied. The patients were assessed with regard to gender, age, type of hip fracture, and type of surgical intervention.
Results:
The overall mortality rate 1 yr after hip fracture was 12.43%, and the mean age was 77.77 yr old. The risk factors most associated with mortality were as follows: advanced age (71 to 80 and 81 to 90 yr old), male, peritrochanteric (extracapsular) fracture, and operative fixation with dynamic hip screw.
Conclusions:
The mortality rate of patients with hip fractures within 1 yr has a high-risk potential, especially for male patients over 71 yr of age with peritrochanteric (extracapsular) fractures. Surgical treatment with dynamic hip screw also was shown to be a risk factor between the different treatment options.
Level of Evidence:
Level IV.
Biomarkers of Systemic Lupus Erythematosus and Systemic Sclerosis diseases ac...Prof. Hesham N. Mustafa
Systemic Lupus Erythematosus (SLE) and systemic sclerosis (SSc) are systemic inflammatory autoimmune disorders characterized by a large spectrum of clinical and laboratory features. The aim of the present study was to investigate the possible use of serum level of soluble intercellular adhesion molecule-1(sICAM-1) and soluble interleukin-2 receptor (sIL-2Ra) as biomarkers for monitoring of SLE and SSc disease activity. Moreover, it aimed to compare the specificity and sensitivity as well as cut-off value of both biomarkers in a sample of Egyptian patients. 50 SLE patients, 30 SSc patients and 60 age and sex matched healthy controls were enrolled in our study. sICAM-1and sIL-2Ra were measured in serum samples obtained from all participants. In addition to Erythosedimentation rate (ESR), complete blood count (CBC), Antineuclearantibodies (ANA) estimation, disease activity of both diseases were also assessed. sICAM-1and sIL-2Ra levels were higher in SLE and SSc patients versus control. Both parameters are correlated with each other as well as the activity parameters. A cut-off levels of 455.59 (ng/ml) &2525935 (pg/ml) in both SLE & SSs respectively was observed with the highest specificity and sensitivity. It could be concluded that sICAM-1 and sIL-2Ra are noninvasive biomarkers for SLE and SSc that could play a pathophysiologic role in development and progression of both diseases. Moreover, sICAM-1 and sIL-2Ra are correlated with the disease activity at cut-off values of 455.59 (ng/ml) & 2525935(pg/ml) respectively.
Morphohistometric study of the ligamentum flavum in cervical,thoracic and lum...Prof. Hesham N. Mustafa
ABSTRACT Anatomic characterization and fine structure of the human ligamentum flavum (LF), especially at different spinal levels, represent an attractive focus for the scientific and surgical application. Descrip-tive anatomical and structural study of LF at the cervical, thoracic and lumbar levels of the vertebral column in human cadavers is carried out here. The aim of the work is to clarify the anatomical features and fine structural differences in the human LF at different vertebral levels (cervical, thoracic and lumbar). Specimens of vertebral column were ob-tained from 34 human preserved cadavers. Their average age ranged between 56 and 69 years. Morphometric parameters including height, width and thickness of the ligament flavum at the mid-levels of cervical, thoracic and lumbar regions were measured. Sections obtained from different levels were stained with different stains. Morpho-metric measurements involved the relative elastic area, relative collagen area, elastic area% and collagen area% were measured.The results of the height, width and thickness of the LF at different spinal levels showed gradual increase in their mean values respectively. The LF midline gaps were found in the cervical, thoracic and lumbar regions. The morphometrical measure-ments showed that the average elastic area was highest in the cervical region and lowest in the tho-racic region. In the lumbar region, the percentages of both elastic area and the collagen area were nearly the same. The characterization of morpho-logical and histological aspects of the LF at differ-ent spinal levels will be of great importance for ap-plications in spinal surgery, biomechanical and physical rehabilitation of vertebral column.Keywords: Ligamentum Flavum – Spinal – Collagen and elastic fibers
Correlation between acl injury and involvement of the anterolateral ligament ...Prof. Hesham N. Mustafa
Background:
Clinical testing has demonstrated the role of the anterolateral ligament (ALL) in controlling anterolateral laxity and knee instability at high angles of flexion. Few studies have discussed the association between an anterior cruciate ligament (ACL) injury and ALL injury, specifically after residual internal rotation and a post-ACL reconstruction positive pivot-shift that could be attributed to ALL injury. The goal of this study was to assess the correlation between ALL injury and ALL injury with concomitant ACL injury using MRI.
Material and Methods:
This was a retrospective study of 246 patients with unilateral ACL knee injuries from a database that was reexamined to identify whether ALL injuries occurred in association with ACL injuries. We excluded the postoperative reconstructed cases. The charts were reviewed on the basis of the presence or absence of diagnosed ACL injury with no regard for age or sex.
Results:
Of the 246 patients with ACL injury, there were 165 (67.1%) patients with complete tears, 55 (22.4%) with partial tears, and 26 (10.6%) with sprains. There were 176 (71.5%) patients with ALL and associated ACL injuries, whereas 70 (28.5%) did not have associated ACL injuries. There was a significant statistical relationship between ACL and ALL injuries (P<0.0001).
Conclusions:
There is high incidence of ALL tears associated with ACL injuries. Clinicians should be aware of this injury and consider the possibility of simultaneous ALL and ACL repair to prevent further knee instability.
Level of Evidence:
Level IV.
Liver ischemia/reperfusion injury, a setting in which the functional mass is ...Prof. Hesham N. Mustafa
Liver ischemia reperfusion is induced during sur-gical procedures like liver transplantation and re-section. Multiple mechanisms have been postulat-ed to liver damage following liver ischemia reperfu-sion injury, such as oxidative stress and inflamma-tory reactions. The present study declares the pos-sible mechanism of tadalafil, toward modulating the inflammatory response. Forty-eight rats were divided into 4 groups as follows; Sham group sub-jected to midline laparotomy only. Tadalafil group administered Tadalafil 10 mg/kg intraperitoneal 45 min before sham operation. I/R (Ischemia-reperfusion) group, rats undergo 60 min of hepatic ischemia followed by 60 min of reperfusion. Tada-lafil + I/R group rats undergo a similar pattern of I/R after the treatment with Tadalafil 10 mg/kg, 45 min before ischemia. At the end of the reperfusion, the blood samples were collected for estimation of biochemical markers including liver enzymes using colorimetric assay method and serum: TNF-α (tumor necrosis factor-α), IL-6 (interleukin 6) le-vels, ICAM- 1 (Intercellular Adhesion Molecule-1) were measured. Tissues were evaluated by semi-quantitative and morphometrical approaches. Ta-dalafil succeeded in restoring normal levels of liverenzymes and ameliorating the oxidative stress as evidenced by decreasing MDA and restoring redu-ced glutathione levels in liver tissue homogenate. Also, Tadalafil exhibits anti-inflammatory effects, as it significantly decreased the levels of TNF-α, IL6 and ICAM-1. The findings are supported by BCL-2, TNF-α immunomarkers. It is concluded that modulation of the inflammatory response might be one of the mechanisms of Tadalafil-mediated he-patoprotection, so it is recommended as an adju-vant therapy in liver surgery.Keywords: Ischemia/reperfusion injury – Oxidative stress – Apoptosis – TNF-α – BCL-2
Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer’s disease ...Prof. Hesham N. Mustafa
Aluminum (Al) is a neurotoxic substance which has played an important role in the etiology, pathogenesis, and development of amyloid-β (Aβ) plaques. This study was carried out to evaluate the neuroprotective effect of aqueous cinnamon extract against aluminum chloride (AlCl3)-induced Alzheimer’s disease. Forty adult male albino rats, randomly divided into four equal groups. Control group; ACE200 group administered aqueous cinnamon extract (ACE) orally; AlCl3 group received daily intraperitoneal (i.p.) injection of AlCl3 for 60 days to induce neurotoxicity and AlCl3 + ACE200 group received a combination of AlCl3 and ACE in the same dose and route as previous groups. Aluminum administration significantly enhanced the memory impairment and the Aβ formation in the rat model. The cerebellum exhibited a significant reduced number of Purkinje cells, marked decrease in the density of dendritic arborization and prominent perineuronal spaces in the molecular layer. There was loss of dendritic spines, neurofibrillary degeneration, and appearance of neuritic plaques. Concomitant administration of AlCl3 and ACE displayed an observable protection against these changes with progressive improvement in memory and intellectual performance. In conclusion, ACE may play a protective role against formation of amyloid-β plaques in cerebellum.
Analytical Study of Clinicopathological Data of Saudi Patients with Osteoarth...Prof. Hesham N. Mustafa
SUMMARY: Knee osteoarthritis (OA) is a common disabling disease. Epidemiological studies have revealed various risk
factors for OA, including sex, aging, obesity, occupational illnesses, and chronic diseases. Here we evaluate the clinical, pathological,
and radiological findings of knee OA in a subset of Saudi patients who were subjected to total knee replacement (TKA). The study
population included 30 Saudi patients with knee OA who were operated by TKA (from June 2014 to December 2015) in the Department
of Orthopedics, Faculty of Medicine, King Abdulaziz University, Saudi Arabia. Patient’s clinical and radiological data were collected
from the hospital files. Pathological examination of the excised superior articular surface of tibia and femoral condyles were done.
Pearson Chi-squared analysis was used to test for differences between the variables in associated risk factors. There were more women
than men. Sixty per cent of patients were older than 60 years [mean age, 59.2 (females) and 61.7 (men) years-old]. All patients exceeded
obesity class 1, with females being more obese than males. Pathological examination of the superior articular surface of tibia and femoral
condyles showed high score lesions, which was more apparent in females than in males. Radiological findings showed that most lesions
were high grade. The findings of this study will help to understand the pathogenesis of OA and improve treatment decision making
relevant to TKA in knee OA in Saudi Arabia and elsewhere.
KEY WORDS: Osteoarthritis; Knee; Arthroplasty.
A Study on the Toxic Effect of Different Doses of Diclofenac Sodium on the De...Prof. Hesham N. Mustafa
SUMMARY: The toxic effects of different doses of diclofenac sodium (DS) on the kidney on the postnatal period (0-7 days) by
morphometrical and immunohistochemical methods were investigated. For this purpose, 15 female adult wistar albino rats were used and
divided into 5 main groups. Group Ia served as normal control, physiologic group Ib received normal saline, group II received low dose (3.9
mg/kg), group III received medium dose (9 mg/kg) and group IV received high dose (18 mg/kg). Male offspring’s from 0-7 days after birth
were used in this study. On the 8th day of postnatal life, all animals were anesthetized. Then, the kidney samples were analyzed. Haematoxylin
and eosin staining showed degeneration and necrosis, apparent atrophy of the glomeruli, mononuclear cell infiltration, congested vessels,
increased fibrous tissue and distortion of the proximal convoluted tubules with interruption of the brush margin of the DS treated group.
Increased level of Caspase-3 and upregulation of TNF-α with different doses of DS. In light of our findings, DS may lead to adverse effects
that are dose-dependent in the prenatal subjected kidney to this drug.
KEY WORDS: Diclofenac sodium; Proximal convoluted tubules; Apoptosis;Cyclooxygenase.
Thymoquinone ameliorates oxidative damage and histopathological changes of de...Prof. Hesham N. Mustafa
ABSTRACT
Lead (Pb) toxicity is known to be a chief environmental health issue, especially for pregnant
women and young children. Today, the use of medicinal herbs in the treatment of many diseases
and different toxic agents has become highly accepted due to their effectiveness and lower costs.
Thymoquinone (TQ), which is extracted from Nigella sativa seeds, is a potent antioxidant and anti
inflammatory agent. This study was designed to explore the optional protectivity of TQ against
maternal and fetal oxidative stress and brain damage induced by Pb administration. Pregnant
rats were distributed into seven groups: control group, TQ group, DMSO group, two groups Pb
treated (160 and 320 ppm), and two groups Pb-treated (160 and 320 ppm) co-treated with TQ.
Administration started from gestation day 1 (GD1) to day 20 (GD20) through oral gavage once
daily. Lead administration caused a dose-dependent toxicity for both mothers and fetuses. Also,
the histopathological assessment of the brains from Pb-treated groups showed marked altera
tions. Co-treatment of with TQ and Pb caused a significant decrease in Pb levels as compared
with those treated with Pb alone and amelioration of histopathological changes in the brains. It
was concluded that co-treatment of TQ along with gestational Pb exposure could mitigate the
effects against Pb-induced maternal and fetal neurotoxicity.
KEYWORDS
Lead; oxidative stress; brain;
Thymoquinone; fetal toxicity
A study on the toxic effect of different doses of Diclofenac sodium on the de...Prof. Hesham N. Mustafa
The toxic effects of different doses of diclofenac sodium (DS) on the kidney on the postnatal period (0-7 days) by morphometrical and immunohistochemical methods were investigated. For this purpose, 15 female adult wistar albino rats were used and divided into 5 main groups. Group Ia served as normal control, physiologic group Ib received normal saline, group II received low dose (3.9 mg/kg), group III received medium dose (9 mg/kg) and group IV received high dose (18 mg/kg). Male offspring’s from 0-7 days after birth were used in this study. On the 8th day of postnatal life, all animals were anesthetized. Then, the kidney samples were analyzed. Haematoxylin and eosin staining showed degeneration and necrosis, apparent atrophy of the glomeruli, mononuclear cell infiltration, congested vessels, increased fibrous tissue and distortion of the proximal convoluted tubules with interruption of the brush margin of the DS treated group. Increased level of Caspase-3 and upregulation of TNF-α with different doses of DS. In light of our findings, DS may lead to adverse effects that are dose-dependent in the prenatal subjected kidney to this drug.
Keywords : Diclofenac sodium; Proximal convoluted tubules; Apoptosis; Cyclooxygenase.
Zingiber Officinale Alleviates Maternal and Fetal Hepatorenal Toxicity Induce...Prof. Hesham N. Mustafa
This study was designed to address the protective effects of Zingiber officinale on the toxic outcomes of prenatal Cadmium administration on pregnancy outcome. Pregnant female Sprague-Dawley rats were randomly divided into four groups (eight rats/each), control group received distilled water, 2nd group treated with 8.8 mg of CdCl2/kg b. wt, 3rd group treated with 250 mg of Zingiber officinale/kg b. wt, and 4th group treated with 250 mg of Zingiber officinale/kg b. wt, followed by 8.8 mg of CdCl2/kg b.wt. Daily body weight of pregnant was recorded from GD1-GD20, and then pregnant rats were sacrificed at GD20. Samples of maternal and fetal livers and kidneys were processed for histological examination. Administration of Cd to pregnant rats showed adverse effects on pregnant mothers and their fetuses; reduced maternal weight gain, reduced absolute organ weights, reduced fetal growth parameters and placental weights together with altered histological appearance of the maternal and fetal livers and kidneys. While co-administration of Zingiber officinale showed an improvement of these toxic alterations. Zingiber officinale through its antioxidant activity could be beneficial against toxic outcomes of Cd exposure during pregnancy.
Evaluation of the safety of conventional lighting replacement by artificial d...Prof. Hesham N. Mustafa
Background
Short morning exposure to high illuminance visible electromagnetic radiations termed as artificial daylight is beneficial for the mental health of people living in geographical areas with important seasonal changes in daylight illuminance. However, the commercial success of high illuminance light sources has raised the question of the safety of long hour exposure.
Methods
We have investigated the effect of the replacement of natural daylight by artificial daylight in Swiss mice raised under natural lighting conditions. Mice were monitored for neurotoxicity and general health changes. They were submitted to a battery of conventional tests for mood, motor and cognitive functions’ assessment on exposure day (ED) 14 and ED20. Following sacrifice on ED21 due to marked signs of neurotoxicity, the expression of markers of inflammation and apoptosis was assessed in the entorhinal cortex and neurons were estimated in the hippocampal formation.
Results
Signs of severe cognitive and motor impairments, mood disorders, and hepatotoxicity were observed in animals exposed to artificial daylight on ED20, unlike on ED14 and unlike groups exposed to natural daylight or conventional lighting. Activated microglia and astrocytes were observed in the entorhinal cortex, as well as dead and dying neurons. Neuronal counts revealed massive neuronal loss in the hippocampal formation.
Conclusions
These results suggest that long hour exposure to high illuminance visible electromagnetic radiations induced severe alterations in brain function and general health in mice partly mediated by damages to the neocortex-entorhinal cortex-hippocampus axis. These findings raise caution over long hour use of high illuminance artificial light.
The Ameliorative Potential of Dexmedetomidine and Benincasa Cerifera Extract ...Prof. Hesham N. Mustafa
Renal ischemia/reperfusion injury (IRI) represents the main reason for acute kidney injury (AKI). Dexmedetomidine (Dex) and Benincasa cerifera (BC) have wide benefits due to their anti-inflammatory and antioxidant properties. This study aims to illustrate the protective effects of BC and Dex on renal IRI in a diabetic model. Sixty adult male albino rats (Wistar strain), weighing 250–300 g, were included in the study. The rats were divided into four groups, as follows: sham group: (non-diabetic); diabetes mellitus (DM) + IRI group: streptozotocin (STZ)-induced diabetic rats exposed to renal IRI on day 30 after diagnosis of diabetes; DM + IRI + BC group: STZ-induced diabetic rats treated with BC (500 mg/kg) for 30 days after diagnosis of diabetes, then exposed to renal IRI; and DM + IRI + Dex group: STZ-induced diabetic rats treated with Dex (100 µg/kg intraperitoneally) 5 min before induction of ischemia on day 30 after diagnosis of diabetes, then exposed to renal IRI. Biochemical parameters, histopathological examination, and immunohistochemical markers were evaluated. A significant improvement in the biochemical, histopathological, and immunohistochemical parameters were observed in the DM + IRI + BC group, while the DM + IRI + Dex group showed improvements in renal IRI and dyslipidemia. The present study demonstrated that oxidative stress plays a chief role in renal IRI in the STZ-induced diabetic model. Treatment with BC achieved excellent ameliorative effects, while treatment with DEX improved renal IRI.
Keywords:
Diabetes; Dexmedetomidine; Ischemia/Reperfusion; Oxidative Stress
Beneficial Effects of Curcumin Inmaternal and Fetal Oxidativestress and Brain...Prof. Hesham N. Mustafa
This study was planned to explore the protective role of curcumin (Cur) against maternal and fetal oxidative stress and cerebral damage induced by lead (Pb) during pregnancy. Positively pregnant female rats were divided into seven groups: control group, Cur group (300 mg/kg of Cur/b.wt.), DMSO group (50% DMSO), two Pb-treated groups (exposed to 160 and 320 mg/kg b.wt./day of Pb acetate, respectively), and two groups treated with both Pb and Cur (exposed to Pb as previous groups together with 300 mg/kg b.wt./day of Cur). Treatments through oral gavage once a day started from gestation day 1 (GD1) till day 20 (GD20), where the mother rats of different experimental groups were sacrificed to obtain the fetuses. Different chemical parameters were assessed. Brain specimens of mother and fetal groups were processed with examination. The results displayed that Pb administration to pregnant rats resulted in a dose-dependent toxicity for both mothers and fetuses. Also, there was a significant rise in lipid peroxidation and decreased antioxidant enzyme activities in the brains of the different Pb-treated groups. The histological examination of the brain of treated dams and fetuses showed marked alterations. Co-treatment of Cur along with Pb caused a significant decrease in Pb levels as compared with those treated with Pb alone, improving the oxidative condition with amelioration of the brain’s histopathological changes. Co-administration of Cur could have ameliorative effect against Pb-induced neurotoxicity through the reduction of oxidative stress and reversal of histopathological changes.
Keywords:
Lead; Oxidative Stress; Brain; curcumin; Fetal toxicity
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
3. 3Get Noticed
GET NOTICED
More than one million scientific
articles are published each year, and
that number is rising. So it’s increasingly
important for you to find ways to
make your article stand out.
While there is much that publishers
and editors can do to help, as the
paper’s author you are often best
placed to explain why your findings
are so important or novel.
This brochure shows you what
Elsevier does and what you can do
yourself to ensure that your article
gets the attention it deserves.
4. 4Get Noticed
PREPARING YOUR ARTICLE
When writing your article it’s important to choose the right journal. The
journal with the right scope can be key to reaching your target audience.
The easiest way for finding an Elsevier journal is using Journal Finder:
journalfinder.elsevier.com.
Also, a good abstract is instrumental. Make sure that your abstract clearly
and concisely explains what is new in your paper and why that is important.
SEO
Optimizing your article for search engines – Search Engine Optimization
(SEO) – helps to ensure it appears higher in the results returned
by search engines such as Google. This helps you attract more readers,
gain higher visibility in the academic community and potentially
increase citations.
Below are a few SEO guidelines:
• Use keywords, especially in the title and abstract.
• Add captions with keywords to all photographs, images, graphs and tables.
• Add titles or subheadings (with keywords) to the different sections
of your article.
For more detailed information on how to use SEO, see our guideline:
elsevier.com/earlycareer/guides.
Give your research the impact it deserves
Content innovations enable you to present your work in a more powerful
form, and make your article stand out from the crowd. You can take
advantage of the features, including the AudioSlides, Graphical Abstracts,
Virtual Microscope, Interactive Map Viewer and 3D Molecular Models,
on ScienceDirect to enhance your article’s value for readers.
Find out which content innovations are available for journals in your
research field: elsevier.com/about/content-innovation.
1
5. 5Get Noticed
‘Audioslides were a great tool for to get the message across to busy professionals
and the general public in 5 minutes with pretty pictures to make it accessible.
Also, it is free so anyone can use it and the resulting presentations are
open access. I think it is a fantastic vehicle to get the research out there.’
Thanh-Lan Gluckman
PhD student, Department of Zoology, University of Cambridge, UK
AudioSlides
AudioSlides are short, webcast-style presentations, which allow you
to present your research in your own words. Elsevier offers you
the option of creating your own unique AudioSlides presentation
which complement your research and provides readers with a short,
succinct overview of the article content. These appear alongside
your article once it is published on Elsevier’s ScienceDirect platform,
home to one-quarter of the world’s STM journal and book content.
AudioSlides are free to access and easy to share, independently from
the article, with colleagues, (influential) bloggers and on social media
including YouTube.
Make the most of your AudioSlides with our useful Tips and Tricks:
elsevier.com/audioslides.
Graphical abstracts
A Graphical Abstract is a visual summary of the main findings of the
article that is placed as part of your article an ScienceDirect and will turn
up in online search result lists. It will help people to understand the key
point of your article at a glance. You can make use of our professional
illustration services at the Elsevier webshop: webshop.elsevier.com.
You can use your graphical abstract as a promotional tool by for
example tweeting it, sharing it on social media or sending it to an
(influential) blogger. Always add a link to your article.
7. 7Get Noticed
PUBLISHING YOUR ARTICLE
Your article on ScienceDirect
Elsevier will publish your article on ScienceDirect, a leading information
solution providing authoritative, full-text scientific, technical and medical
content from Elsevier.By optimizing the platform and indexing all
content, Elsevier works to ensure that your article is more visible and
can be found more easily by search engines, library discovery services,
AI databases, and other innovative search and discovery tools.
Your article will be accessible immediately after acceptance, and have
a unique DOI (Digital Object Identifier), that will always link to the
latest available version of your article. Elsevier also participates in the
multi-publisher initiative CrossRef, which enables articles that cite you
to link directly to your paper. The CrossMark logo in online PDF or
HTML documents helps readers to verify that they are using the most
recent and reliable version.
Table of Contents Alert
When your article is published, a link is sent to everyone who has
subscribed to the journal’s free Table of Contents email alert.
Editors’ Choice
Your article may be selected for Editors’ Choice: the top five articles the
editor has chosen to highlight from those published in their journal over
the past 12 months. Editors write a recommendation illustrating why
they have chosen these articles and the papers are freely accessible to all
readers for up to one year.
Research Highlights app
Research Highlights is a free Elsevier app for smartphones and tablets
that highlights your article to users on the basis of search terms.
Readers can preview your article abstract in-app, then send the full text
link to their inbox. See more at: researchhighlights.elsevier.com
2
9. 9Get Noticed
PROMOTING YOUR ARTICLE
conferences
Presenting and networking at conferences personalizes your work,
giving it a face and a voice, and it can create new opportunities for
collaboration. Make sure you connect with other delegates on Facebook
and LinkedIn, and direct them to your website or blog.
If you create a poster for a conference, perhaps accompanied by flyers,
you can also post them on your website, and provide links on your blog,
social media profiles, online CV, or institutional page.
Media relations
Research statement
If you would like journalists, media outlets and the public to pick up
on your published paper, it can help to have a brief statement prepared
which explains the significance of your research and its key outcomes
in simple language. This statement can be used as a basis for
press releases or sharing on social media.
Make use of your institution’s communications channels
If you’re affiliated with a particular institution, chances are that it sends
out press releases to local media, and publishes one or more internal
newsletters. Increasingly, institutions also have their own press office
and PR/media staff. Get in touch with them to see what they can do to
help you promote your published paper.
3
10. 10Get Noticed
Media outreach by Elsevier
Elsevier promotes selected research papers to the global scientific media.
The channels available for this are: press releases, the Elsevier Research
Selection (bi-weekly email sent out to more than 1600 subscribing
journalists) and Elsevier Connect (Elsevier’s online platform with daily
stories by science, technology and health professionals).
If you think your article is interesting for a wider audience and/or
would like more information about any of the above, contact us at
researchcomm@elsevier.com to explore the possibilities.
Get started
Write a research statement
Share your research statement with relations and (influential bloggers)
Make use of your institution’s communication channels
Contact Elsevier if you think your article is interesting for
a wider audience
Share your article
Sharing your research and findings can help you make a greater impact
in your community, leading to better collaborations and potential new
ideas and innovations. Millions of researchers have access to your
formal publication hosted on ScienceDirect helping users to find, access,
and cite your research using the best available version.
11. 11Get Noticed
Share link
Elsevier will send you a ‘share link’: a personal, customized short
link that you will receive after final publication of your article.
It provides 50 days free access to your newly-published article on
ScienceDirect to anyone clicking on the link. We encourage you
to share this link on social media. After 50 days the share link will
still work but automatically revert to a link to your full text article.
The more links there are to your article from a range of relevant
websites, the more readers you’ll attract and the higher it will appear
on search engine results.
Mendeley
Mendeley is a powerful reference manager and an academic social net-
work with more than 3 million users. Create a free account to discover
relevant research, connect and collaborate with the global community.
Get started
Start a free account at mendeley.com and explore
Be discovered online
It’s important people can find you and links to your publications online.
If you have a personal page at your institute, include links to the
final version your articles on that page. There are also a few easy tools
available to help you increase your online visibility.
12. 12Get Noticed
ORCID and Scopus author profiles
Elsevier’s Scopus is the world’s largest abstract and citation database
of peer-reviewed literature and it features smart tools to track, analyze
and visualize research. When you’ve published an article in any peer-
reviewed journal, you automatically have a Scopus profile. It is a good
idea to check and update your profile containing the right publications.
ORCID (Open Researcher and Contributor ID) seeks to remedy the
systemic name ambiguity problems seen in scholarly research by
assigning unique identifiers linkable to an individual’s research output.
You can now update both your Scopus and your ORCID at
orcid.scopusfeedback.com. Please follow the easy steps online.
LinkedIn
This networking site is used professionally by 65 percent of the researchers
we surveyed. Create a profile and post your latest accomplishments.
You can enhance your profile by adding research findings, articles,
images, videos, SlideShare presentations and audio recordings
(for example, your AudioSlides presentation). You can also join relevant
groups and connect with other researchers in your discipline.
Get started
Create a profile on linkedin.com
Add a picture and your CV
Reposition the publication section to a more prominent position
at the top of your profile
13. 13Get Noticed
Include any relevant honors and awards
Enhance your profile with images, Graphical Abstracts,
AudioSlides and video
Personal website
Whereas LinkedIn is good for connecting and summarizing your
research, your own website gives people a better sense of who you
are. Create a personal professional website highlighting your research
findings, achievements, publications and ambitions. Post videos or
images to create a buzz around posters or conference presentations.
Always include links to your articles, and link to your website in your
email signature, and on all of your online and social media profiles,
to get maximum exposure. You can also add links to your academic
social networks, Facebook, LinkedIn, Twitter and other accounts.
Get started
Pick a url at which to register your website. Try your name or a
combination of initials and last name. You can check availability of urls
and register them on sites such as GoDaddy, or DomainRegistry.com.
Once you’ve registered a url, you can start creating your website.
Use a platform such as WordPress, Weebly, Yola or Jigsy.
Not all websites offer hosting, but WordPress, Weebly and Yola are
among those that do. If a platform doesn’t offer hosting, you can find a
commercial provider which does.
Use keywords in the text and metadata to increase the number of
visitors who find your page through search engine searches.
For more information see elsevier.com/earlycareer/guides
14. 14Get Noticed
Blog
Blogs are proven to be effective in promoting your research and having
an impact. You can promote in-depth conversation via your blog, and
build credibility by sharing information and responding to feedback from
other researchers. Blogs require a regular time commitment. You may
consider your blog a good exercise in learning how to communicate
science to the public.
Once you’ve started your blog, write regular updates to showcase your
research undertakings and other topics of interest. Make sure you
provide links to your journal articles and publications. Readers can follow
and subscribe to your posts, leave comments, and start conversations.
Get started
Register with one of the several blogging websites and start designing
your website.
Invite friends and colleagues from your network to follow your blog.
Some of the most popular sites offering simple-to-use blogging are
Blogger, WordPress, TypePad and MovableType.
Social media
Every day, scholarly articles receive 12,000 new mentions across
social media, news and blogs: that’s one mention every seven seconds!
It’s a powerful medium for reaching your potential readers.
You don’t have to be on all social media – it can be best to find one or
two channels that suit you and your purposes.
15. 15Get Noticed
Facebook
Facebook is a popular social media tool, but you can also leverage it for
professional purposes. You can share photos, status updates and links
regarding your research with your Facebook friends. Recent research1
shows that the richness of the content that you share on Facebook raises
the impact of the post, i.e. posting images and videos during business
hours has a positive impact on Facebook likes and comments.
You can also join groups catering for your field of expertise, connect with
like-minded research professionals and use Facebook as a collaborative
space to share with fellow researchers.
Get started
Make a profile on facebook.com
If you want to keep your regular profile for only social purposes,
create an author page for your professional endeavors
Invite fellow researchers to be a friend
Discuss ideas and carry out debates
Link to your articles
Share images, videos and audio recordings, e.g. AudioSlides,
and a Graphical Abstract
Recruit participants for research
Join groups related to your research field
1
Sabate, Ferran, 2014. “Factors Influencing popularity of branded content in Facebook
fan pages”. European Management Journal. DOI: 10.1016/j.emj.2014.05.001
16. 16Get Noticed
WeChat
WeChat is a fast growing instant messaging social network in China,
but you can also leverage it for professional purposes. This mobile-based
app offers you a great way to share photos, status updates and links
regarding your research with your WeChat friends.
You can also join groups catering for your field of expertise, connect with
like-minded research professionals and use WeChat as a collaborative
space to share with fellow researchers.
GET STARTED
Install the app on your mobile phone
Sign up with your phone number and make a profile
Add your friends to your Contacts by scanning your mobile contacts or
searching their WeChat ID, phone number, or QQ ID
Invite fellow researchers to be a friend
Discuss ideas and carry out debates in your groups
Link to your articles
Share images, status updates and links regarding your research
Ask your friends to add you to groups related to your research field
S
17. 17Get Noticed
Weibo*
Known as Chinese Twitter, Weibo is one of the most popular social
network in China. It gives you a chance to share quick thoughts using
no more than 140 characters and 9 pictures. Today, millions of people
are active on Weibo. It’s a great way to share your current research,
publications and links to new blog posts.
GET STARTED
Make a profile on weibo.com
If you want yourself and your research field to be discovered easier,
apply for verification for your account
Follow other researchers and thereby increase your own following
Post regular content, e.g. links to hot papers, events and conferences
Respond promptly to direct messages and comments
Repost. By promoting other members of your community you are
raising your own profile at the same time
Use images. A picture is twice as likely to be reposted as text
* “Weibo” is often used generically to refer to Sina Weibo.
18. 18Get Noticed
Twitter
Twitter gives you a chance to share quick thoughts using no more
than 140 characters. Today, one third of all scholars are active on Twitter.
It’s a great way to share your current research, publications and links to
new blog posts.
Get started
Make a profile on twitter.com
Follow other researchers and thereby increase your own following
Post regular content, e.g. links to hot papers, events and conferences
Respond promptly to direct messages and comments
Retweet. By promoting other members of your community you are
raising your own profile at the same time
Use images. A picture is twice as likely to be retweeted as text
Reddit site
On the popular bookmarking site Reddit, people share interesting
articles in sections dedicated to a wide range of topics, including specific
scientific fields. This is a way to communicate with a wider audience on
your research topic.
19. 19Get Noticed
Google+
Google+ makes it easier for you to be discovered online, and it’s
integrated with other Google services such as Gmail and YouTube.
Get started
Start an account or upgrade your current one if you have a Gmail or
YouTube account
Introduce yourself and add a picture
Connect with fellow researchers
Share links to your articles, AudioSlides, Graphical Abstract,
and conferences
Use Google Hangouts to hold online video meetings where you can
share and view documents
Wikipedia
Wikipedia is the well-known, free, online encyclopedia where registered
users can create and edit entries. Not everyone can have a Wikipedia
page; once you’ve published several books and articles, and have
gained a solid reputation in your field, you have a better chance of
successfully obtaining one. Links to your article from a Wikipedia page
will dramatically increase your SEO. You can try to include an entry
with a link to your article on a relevant topic page. Wikipedia has many
guidelines for writing an entry, so check its website for more details.
21. 21Get Noticed
MONITOR YOUR ARTICLE
After promoting your article, you’ll want to know how it’s been received.
Elsevier helps you monitor your success in a variety of ways.
My Research Dashboard
Any author who has published at least one article with Elsevier
within the last 10 years will be invited to register for a personalized
dashboard, offering:
• Early feedback on how your publications are being downloaded,
shared and cited;
• data about the geographic locations and research disciplines
of your readers;
• detailed information about search terms used in ScienceDirect
to find your publications; and
• a comparison of the performance of your article with other articles
Have you not been invited to register for your personal dashboard yet?
Don’t worry, as it will certainly happen soon. In the meantime,
you will continue to receive our current services:
• CiteAlert, a weekly service that automatically notifies you by email
when your work is cited by an article in an Elsevier-published journal.
• Article Usage Alerts, a quarterly email for authors notifying
them of the usage of their article for the first year after publication.
Altmetrics
Who’s talking about papers online and what’s being said? Altmetrics
allow you to track and analyze online activity around your article.
Online article mentions are monitored from social media sites
(e.g. Twitter, Facebook, Google+), science blogs, many mainstream
media outlets (including the NY Times, The Guardian, non-English
language publications like Die Zeit and Le Monde and special
interest publications like Scientific American, and New Scientist)
and reference managers for mentions of academic papers.
4
22. 22Get Noticed
Conclusion
Getting noticed today means using
the abundant online and social media
tools available to better promote
your research findings and publications
to a wider audience of researchers.
As a result, not only will your research
become more visible, but you’ll also
attract more readers, potentially increase
citations, build a stronger reputation
and expand your professional network.
The efforts you make online today will
make you stronger offline tomorrow –
so get involved, and get noticed!