22062023 Endometrial cancer risk factors all must know.pptxNiranjan Chavan
Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ where fetal development occurs. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. Endometrial cancer is sometimes called uterine cancer.
Breast cancer is increasing year by year in India and we are moving towards western statistics in prevalence of disease.
I was invited by air force gandhinagar to deliver the breast cancer awareness talk to their staff.
This presentation is all about breast cancer, early signs, symptoms, prevention, diagnosis and treatment.
Cancer that
forms in the tissue lining the uterus (the small, hollow, pear-shaped
organ in a woman's pelvis in which a fetus develops). Most endometrial
cancers are adenocarcinomas (cancers that begin in cells that make and
release mucus and other fluids).
NCI
22062023 Endometrial cancer risk factors all must know.pptxNiranjan Chavan
Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ where fetal development occurs. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. Endometrial cancer is sometimes called uterine cancer.
Breast cancer is increasing year by year in India and we are moving towards western statistics in prevalence of disease.
I was invited by air force gandhinagar to deliver the breast cancer awareness talk to their staff.
This presentation is all about breast cancer, early signs, symptoms, prevention, diagnosis and treatment.
Cancer that
forms in the tissue lining the uterus (the small, hollow, pear-shaped
organ in a woman's pelvis in which a fetus develops). Most endometrial
cancers are adenocarcinomas (cancers that begin in cells that make and
release mucus and other fluids).
NCI
breast cancer is the malignent condition of breast and it is the 2nd most common cancer in females with needs to be special attention as it its a very private things for female for early detection and its treatment, and provide a brief knowledge regarding breast cancer to all the nursing students and for their application in their c
#Breast Mass :
Objective :-ANATOMY
PHYSIOLOGY
BLOOD SUPPLY
LYMPHATIC DRAINAGE
#Anatomy of breast
#Lymphatic drainage of breast
#Anatomy of pectoral region
#Devlopement and Physiology of Breast
#Fibroadenomas
#Cystosarcoma phyllodes (CSP)
#Fibrocystic Breast Disease
#Duct Ectasia
#Galactocele
#INTRA-DUCTAL PAPILLOMA
#Gynecomastia
#FAT NECrosis
breast cancer is the malignent condition of breast and it is the 2nd most common cancer in females with needs to be special attention as it its a very private things for female for early detection and its treatment, and provide a brief knowledge regarding breast cancer to all the nursing students and for their application in their c
#Breast Mass :
Objective :-ANATOMY
PHYSIOLOGY
BLOOD SUPPLY
LYMPHATIC DRAINAGE
#Anatomy of breast
#Lymphatic drainage of breast
#Anatomy of pectoral region
#Devlopement and Physiology of Breast
#Fibroadenomas
#Cystosarcoma phyllodes (CSP)
#Fibrocystic Breast Disease
#Duct Ectasia
#Galactocele
#INTRA-DUCTAL PAPILLOMA
#Gynecomastia
#FAT NECrosis
CANSA highlights the importance of screening and early detection for breast cancer as part of its Women’s Health Campaign this October.
http://www.cansa.org.za/womens-health/
Apart from non-melanoma skin cancer, breast cancer is the most common cancer in women of all races, with a lifetime risk of 1 in 35 in South Africa, according to the 2007 National Cancer Registry.
“We encourage all women to conduct regular self-examinations once a month. Know how your breasts look and feel – discuss any changes you observe with your health practitioner. It’s also very important to go for a mammogram every year from the age of 40,”
Breast self Examination for Nursing Student. Procedure Of Breast Self examination. Component of Breast self Examination. Nurses Role in Breast Self Examination.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
7. What can be done?
Early detection!
• Monthly Self Examination
• Clinical Examination
• Annual Mammography Test
8. Monthly Self Examination
• Understand your body.
• Monthly examine your breast and underarm
area
• Start from the early age of 18
• Changes are noticeable
9. Clinical Breast Examination
• Should be performed by a doctor
• Annually for woman above 30 years of age
• Every six months for high risk patients
11. Monthly Self Examination
Step 1
•Begin by looking at your breasts in
the mirror with your shoulders
straight and your arms on your hips.
•Here's what you should look for:
• Breasts that are their usual size,
shape, and color
• Breasts that are evenly shaped
without visible distortion or swelling
Content taken from breastcancer.org
12. Monthly Self Examination
Step 1
•If you see any of the following changes, bring
them to your doctor's attention:
•Dimpling, puckering, or bulging of the skin
•A nipple that has changed position or an
inverted nipple (pushed inward instead of
sticking out)
•Redness, soreness, rash, or swelling
Content taken from breastcancer.org
13. Monthly Self Examination
Step 2
Now, raise your arms and
look for the same changes.
Content taken from breastcancer.org
14. Monthly Self Examination
Step 3
While you're at the mirror, look for any signs of
fluid coming out of one or both nipples (this
could be a watery, milky, or yellow fluid or
blood).
Content taken from breastcancer.org
15. Monthly Self Examination
Step 4
Next, feel your breasts while lying
down, using your right hand to
feel your left breast and then your
left hand to feel your right breast.
Use a firm, smooth touch with the
first few finger pads of your hand,
keeping the fingers flat and
together. Use a circular motion,
about the size of a quarter
Content taken from breastcancer.org
16. Monthly Self Examination
Step 4 continue
•Cover the entire breast from top to bottom, side
to side from your collarbone to the top of your
abdomen, and from your armpit to your
cleavage.
Content taken from breastcancer.org
17. Monthly Self Examination
Step 4 continue
Follow a pattern to be sure that you cover the whole breast. You
can begin at the nipple, moving in larger and larger circles until you
reach the outer edge of the breast. You can also move your fingers
up and down vertically, in rows, as if you were mowing a lawn. This
up-and-down approach seems to work best for most women. Be
sure to feel all the tissue from the front to the back of your breasts:
for the skin and tissue just beneath, use light pressure; use medium
pressure for tissue in the middle of your breasts; use firm pressure
for the deep tissue in the back. When you've reached the deep
tissue, you should be able to feel down to your ribcage
Content taken from breastcancer.org
18. Monthly Self Examination
Step 5
Finally, feel your breasts while
you are standing or sitting. Many
women find that the easiest way
to feel their breasts is when their
skin is wet and slippery, so they
like to do this step in the shower.
Cover your entire breast, using
the same hand movements
described in step 4.
Content taken from breastcancer.org
19. Few Self Examination Videos
https://www.youtube.com/watch?v=ZWpbkz7ZrBw
https://www.youtube.com/watch?v=UnJbwx9ncvY
20. Apprehensions and Myths
• Mammography leads to Cancer
• Too much Breast touching leads to Breast Cancer
• Talking about Breast Cancer leads to Breast Cancer
• Men don’t get Breast Cancer it affects only Women
• Breast cancer is contagious.
• Antiperspirants and deodorants cause breast cancer.
21. Apprehensions and Myths
• Wearing an underwire bra increases Breast Cancer
• Only big Breast woman get Breast Cancer
• Injury to Breast leads to Breast Cancer
• All Lumps in the Breast are Cancer
• Breast Cancer is curable if detected early