The document outlines a webinar on applying brain-based principles for engagement in virtual classrooms. The webinar objectives are to provide six brain-based guidelines to increase novelty, contrast, meaning and emotion in virtual learning. The webinar will present an infographic to reinforce these brain-based learning approaches. It then covers the principles of neuroplasticity, active engagement, vision being the dominant sense, social learning through mirror neurons, embracing failure as part of learning, and using practice to make learning permanent. Examples and implications for each principle are discussed.