This document discusses brain-based teaching strategies that support long-term retention. It explains how memories are processed and stored in different areas of the brain. The four main lobes (parietal, frontal, temporal, occipital) and hippocampus are involved at different stages of encoding, consolidating, and retrieving memories. The document then provides examples of instructional strategies teachers can use to enhance long-term memory, such as giving handouts before lectures, priming students with advance organizers, modeling executive functioning skills, and providing retrieval practice through low-stakes assessments. Suggested accommodations for students with memory deficits include notes, checklists, activating prior knowledge, and self-evaluation.