This document discusses various aspects of bracket prescriptions and their manipulation in orthodontic treatment. It begins by defining terms like angulation, tipping, torque, and inclination. It then compares different bracket systems like Edgewise, pre-adjusted Edgewise, and Roth and how they have evolved over time. The document specifically compares the Roth and MBT prescriptions, noting differences in tip and torque values. It discusses how bracket prescriptions can be altered through inverting, switching, swapping, or blending brackets. The concept of hybrid positioning and hybrid bracket systems is introduced. The document concludes with an overview of customized CAD/CAM brackets fabricated based on a patient's specific dental morphology and treatment plan.