in 1883, a Mexican astronomer, José Bonilla, saw 450 unidentified objects crossing before the sun.
His editor dismissed the phenomenon and suggested it was caused by insects and bugs on the telescope.
In 2011, a group of researchers reanalyzed the data, and discovered the horrifying truth, that The Human Race was going to extinct!
Turns out, the objects were actually fragments of a billion-tone comet passing within a few hundred to few thousand kilometers of Earth, with the energy to wipe out the human race completely, same as the one which caused the extinction of Dinosaurs.
Astrophysics & Cosmology Masterclass November 2021Peter Coles
Slides used during a Science Week event at Maynooth University on 12th November 2021. These are the slides for the Cosmology part of the event which was run by Peter Coles and John Regan of the Department of Theoretical Physics at Maynooth University.
Astrophysics & Cosmology Masterclass November 2021Peter Coles
Slides used during a Science Week event at Maynooth University on 12th November 2021. These are the slides for the Cosmology part of the event which was run by Peter Coles and John Regan of the Department of Theoretical Physics at Maynooth University.
Bioinformatix' Rx&You: Enterprise Intelligence for MedicationsBioinformatix LLC
RX&YOU: A DIGITAL HEALTH SOLUTION DELIVERING BILLIONS IN VALUE
We are inventing the future of medication healthcare by combining five technologies to rank the efficacy of every regimen at genomic levels while simultaneously maximizing care quality and reducing costs by billions of dollars.
FOUR GLOBAL & MULTI BILLION $ PROBLEMS IN DIGITAL HEALTH:
1. MEDICATION NON-ADHERENCE – “Drugs don’t work in patients who don’t take them,” said US Surgeon General, and an est. 50% of patients don’t, costing an est. $535 billion in preventable medical expenses. According to WHO “increasing the effectiveness of adherence interventions may have a far greater impact on [population] health than any improvement in specific medical treatments.”
2. ADVERSE EVENTS – 180K patients die per year in the US from adverse medication events and interactions, making it the 4th leading cause of death. FDA, and soon 27 states, have begun requiring e-reporting of adverse events.
3. CARE COORDINATION – The average American sees 18 providers as an adult with older and sicker patients seeing an average of 28 with prescriptions from many pharmacies. Healthcare now requires a team; however, providers don’t have visibility to each other, much less what they’re prescribing and doing for their common patients.
4. PERSONALIZED MEDICINE - Comparative effectiveness research (CAR) is a Holy Grail of modern medicine – to learn which regimens are most efficacious, safest, and the best value, then to determine it more precisely based on patients’ genomic variants. Rx&You can do this and be a codex of the era of personalized medicine.
SOLUTION:
Our cloud platform ingests and collects streams of patient data, including from the IoT, transforms it into meaning, and acts. Patients receive alerts, in their preferred ways, when and how to take medications, while interactions are prevented via 100% screening, and they e-report adverse events in real-time. Providers receive team-wide reports and real-time alerts from AI rules and predictive analytics enabling them to intervene to prevent expensive medical consequences by getting the right info to who needs it most at the right times.
ICLR Friday Forum: Near-Earth Asteroid Impact (December 13, 2019)glennmcgillivray
On Friday, December 13, 2019, ICLR conducted a webinar titled 'Near-Earth Asteroid Impact: A Rare but Interesting Hazard', led by Clark R. Chapman, Senior Scientist (Retired), Dept. of Space Science Southwest Research Institute, Boulder, Colorado.
Death or property damage by an asteroid strike is an extremely unlikely hazard. Indeed another major mass-extinction, like what happened 66 million years ago when dinosaurs and many other species were extinguished, or even a civilization-threatening impact by an asteroid 1 or 2 km in diameter, is extraordinarily unlikely. But the ancient craters in Canada and other geologically stable subcontinents on Earth reflect the fact that occasional bombardment of our planet continues. There has been much success in the last two decades in detecting asteroids that could cause such totally devastating impacts. Of the more than 95% of them detected, none will strike Earth within the next century. But there has also been increasing realization that much more common impacts by much smaller asteroids are a significant hazard, even if much less frequent or dangerous than the usual natural or human-caused disasters. For instance, 1500 people were sent to hospital in western Siberia in 2013 when a 20-meter asteroid exploded with the force of a half-megaton bomb over the city of Chelyabinsk. The current low level of risk could be further and sharply reduced during the next decade if current telescope facilities are completed and become operational. If a small, oncoming asteroid can be detected before it strikes, it is technically possible to deflect it or at least provide warning in time to evacuate ground-zero.
A slideshow that I made regarding the K.T extinction. Includes one main theory and several others. Leave a like or comment if you enjoyed and hope you survive the next extinction...
Is Space Exploration Worth the Money (in 3d)Rahul Jaiswal
The ppt is actually in 3D so put on your 3D (red and cyan) glasses to watch it properly.
The images may seem to have copyright problem so dont claim it yours.
The universe: why does it exist? Why is there something rather than nothing? Where and why did structure arise: galaxies, and clusters of galaxies. This slide show is a full history of enquiry into how structure arises in the universe. It goes from Plato and Aristotle to the Nobel Prize in Physics 2011. The title Heart of Darkness refers to a book that has the full story: Heart of Darkness, by Jeremiah P Ostriker and Simon Mitton, ISBN 978 0691134307
The 12 biggest objects in the universe presented in a 5 inch screen, how crazy is that?. Be amazed of what the universe holds, be ready to blow your minds.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
2. Fatemeh Majd 2
Observation
More than 400 Misty Objects in front of the Sun
August 12, 1883
Mexican Astronomer: José Bonilla
Saw 450 dark, unidentified objects crossing before the Sun
Each one surrounded by a glowing mist.
But no one else on Earth saw such a thing.
IMAGE PLACEHOLDER
3. Fatemeh Majd 3
No One Believed
His editor dismissed the phenomenon
iFlecks of Dust
iBugs Obscuring the Telescope
iUFOs
5. Fatemeh Majd 5
So What Was It?
Shocking!!!
Fragments of a billion-ton comet
size from 50 to 800 meters across and that the
parent comet must originally have tipped the
scales at a billion tons or more
Passing within a few hundred kilometers of Earth
between 600 km and 8000 km of Earth. That’s
just a hair’s breadth.
Each at least as big as the Tunguska object
So if they had collided with Earth we would
have had 3275 Tunguska events in two days,
probably an extinction event.
How close Earth may have come to catastrophe
Bonilla observed these objects for about three
and a half hours over two days. This implies an
average of 131 objects per hour and a total of
3275 objects in the time between
observations.
In 2011, National
Autonomous University of
Mexico reanalyzed the
observation
6. Fatemeh Majd 6
Tunguska Event
What happened?
• It is the largest impact event on Earth in recorded
history.
• Occurred near the Podkamennaya Tunguska River in
what is now Krasnoyarsk Krai, Russia, at about 07:14
KRAT (00:14 UT) on June 30, 1908.
• The size of the object is estimated on the order of 60
m to 190 m.
• The energy of the blast was most likely between 10
and 15 megatons of TNT and about 1,000 times
greater than that of the atomic bomb dropped on
Hiroshima, Japan
IMAGE PLACEHOLDER
7. Fatemeh Majd 7
Tunguska Event
What happened?
• The Tunguska explosion knocked down some 80
million trees over an area of 2,150 square kilometers.
• The shock wave from the blast knocked people off
their feet and broke windows hundreds of kilometers
away.
• It produced fluctuations in atmospheric pressure
strong enough to be detected in Britain.
• Over the next few days, night skies in Asia and Europe
were aglow; it has been theorized that this was due to
light passing through high-altitude ice particles that
had formed at extremely low temperatures
IMAGE PLACEHOLDER
8. Fatemeh Majd 8
What Can We Do?
What about future impacts?
! Monitor
Find and Monitor near Earth objects
The first thing to do is to find and monitor near Earth objects above a
certain size. NASA is already doing a pretty good job with that, but the work
is not over as they are still finding more and more every year. Calculating
their orbits far in the future is the next step, and if any seem to be coming a
bit too close to Earth, we need to monitor them extra-closely and refine
orbits until we are sure one way or the other.
Test stuff
The second part is having the capabilities of rapidly deflecting an inbound
object. Ideally we would have all this stuff tested and ready to go within a
relatively short time frame, rather than having to actually do the R&D and
build the stuff after we've discovered a dangerous orbit. You don't want
your test-run to have millions, if not billions, of lives hanging in the
balance...
🔑 Be Ready