1. *BLOOD
TRANSFUSION
- Dr.Chintan
(9441375293)

2. *
* Blood loss – accidents, surgical operations
* Severe anemia
(Pregnancy & emergency surgery
– quick restoration of Hb)
* Exchange transfusion
* Blood diseases – Aplastic
anemia, agranulocytosis, leukemias, hemophilia, purpura, clotting &
bleeding disorders
* Acute CO poisoning

3. *
* Donor selection
* Cross matching
* Major – Donor cell with recipient plasma
* Minor – Recipient cells with donor plasma
* Universal donor (O –ve)
* Universal recipient (AB +ve)

4. *

8. *
* Chills, rigors, fever, skin rash, itching, urticaria
* Anaphylactic shock
* Circulatory overload
* Iron overload – hemosiderosis
* Transmission of diseases, alloimmunization
* Infection
* Thrombophlebitis
* Air embolism
* Hyperkalemia
* Hypocalcaemia
* Hypothermia → cardiac arrest → sudden death

9. *
* Hemolysis – hemoglobinemia & hemoglobinuria (red urine), heart rate
↑, BP ↓, dyspnea, bronchospasm, nausea, vomiting,, pulmonary
edema, CCF…………. Jaundice
* Chest pain, back pain
* Renal stone
* Renal shutdown – anuria
* Renal vasoconstriction, circulatory shock, kidney tubules blockage
* Uremia, Coma, death
* TRALI, FNHTR, DHTR, GVHD

10. *
* 1 unit of blood (300 ml) – every 3 months
* ACD mixture (21 days)
* Cold storage
- RBC swell (loss of K, ↑ in Na, water)
- 80 % - 24 hrs. – Destroyed at 1% / day
- WBCs, Platelets – absent after 24 hrs.
* Blood components – PCV, FFP, Platelets

11. *THANQ……