SlideShare a Scribd company logo
Dr. Markus Roggen
President / CSO
Birds, Bees and Buds:
How to Talk About Cannabis
and How to Label it Correctly
Math Class
Sorry, no sex ed. today
Exam Question 1
Mary Jane bought an eight of Lemon OG.
This strain has 23.3% total THC.
She then rolls one half-gram joint.
If she takes three puffs, how much THC, in millimole, has she
consumed?
Exam Question 2
Bubba Kush has 20.2% THC and costs $4.20 per eight.
Lemon OG has 23.3% THC and costs $7.10 per eight.
Which one gives me the most bang for my buck?
Exam Question 2
Bubba Kush has 20.2% THC and costs $4.20 per eight.
Lemon OG has 23.3% THC and costs $7.10 per eight.
Which one gives me the most bang for my buck?
Cost per %point of THC:
Bubba Kush: $0.21
Lemon OG: $0.30
Outline
• How do we buy cannabis today?
• But total THC% is wrong and you lose money!
• Current labeling is bad
• New approaches to labeling
Introduction
DELIC Labs is a research venture that seeks to add fundamental
scientific insight to the field of cannabis and mushroom
production.
We seek to support the cannabis and mushroom industries by
establishing a centralized hub in Vancouver, BC, for collaborative
research focused on:
• Process Design
• Process Optimization
• Process Analytics
• Formulation Research
Collaborative Research
DELIC Labs collaborates with academic, industry and private
groups around the globe. Some highlights of those collaborations
are:
• University of British Columbia, Vancouver
• Loyalist College, Belleville
• Via Innovations by Dr. Monica Vialpando
• Verdient Science by Dr. Linda Klumpers
Fundamental Collaboration
• Chemometrics and data analytics for process control and
optimization
• Kinetic studies to understand mechanisms
• In-process analytics for process control
• Computational studies to understand mechanisms
• Process development, like crystallization
Fundamental Cannabis and Mushroom Chemistry
Research Topics
How do We Buy Cannabis
Today?
Statistics on cannabis sales. Yes, more math!
The Economics of Labeling
• Consumers look at the %THC number and chose the highest.
• Which other industry does that?
The Economics of Labeling
• Consumers look at the %THC number and chose the highest.
• Which other industry does that?
• Pharma? No!
The Economics of Labeling
• Which is the best wine?
The Economics of Labeling
• Which is the best wine?
The Total THC% Problem
• This is a pure THCA crystal: 100% THCA
• Use following formula to calculate total THC%
• 𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877 + ∆9𝑇𝐻𝐶 %𝑤𝑡. = total THC%
• Therefore this pure THCA crystal has 87.7% total THC!?!
The Total THC% Problem
• A pure THCA crystal must have 100% total THC
• Old Formula
• 𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877 + ∆9𝑇𝐻𝐶 %𝑤𝑡. = 𝑡𝑜𝑡𝑎𝑙 %𝑇𝐻𝐶
• We have to add term for weight loss of sample
•
𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877+∆9𝑇𝐻𝐶 %𝑤𝑡.
(𝑃𝑟𝑜𝑑𝑢𝑐𝑡 − 0.123∗𝑇𝐻𝐶𝐴)
= 𝑡𝑜𝑡𝑎𝑙 𝑇𝐻𝐶%
The Total THC% Problem
• You are underreporting the amount of THC in your products.
• You are losing $$$ per pound of flower.
• Very rough estimate:
23.28 20.15
24.12
20.72
0
5
10
15
20
25
30
Lemon OG Bubba Kush
Total
THC
(%)
Figure 1: Cannabis Change in Total
THC
total THC% using new formula
total THC% using current formula
The Total THC% Problem
• You are underreporting the amount of THC in your products.
• You are losing $$$ per pound of flower.
• Very rough estimate:
•>$400 million
missed for USA sales 2022
23.28 20.15
24.12
20.72
0
5
10
15
20
25
30
Lemon OG Bubba Kush
Total
THC
(%)
Figure 1: Cannabis Change in Total
THC
total THC% using new formula
total THC% using current formula
The Total THC% Problem
• You are underreporting the amount of THC in your products.
• You are losing $$$ per pound of flower.
• And your hemp is hot!
0.29
0.24
0.30
0.25
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
Autopilot Hemp Belle W37
Total
THC
(%)
Figure 2: Hemp Change in Total THC
total THC% using new formula
total THC% using current formula
Labeling Mess
Customer needs an advanced degree in mathematics
• Flower: weight percentage, i.e. THC%
Labeling Mess
Customer needs an advanced degree in mathematics
• Flower: weight percentage, i.e. THC%
• Vape cartridges: THC% or mg/g
Labeling Mess
Customer needs an advanced degree in mathematics
• Flower: weight percentage, i.e. THC%
• Vape cartridges: THC% or mg/g
• Edibles: THC in milligrams per unit.
Labeling Mess
Customer needs an advanced degree in mathematics
• Flower: weight percentage, i.e. THC%
• Vape cartridges: THC% or mg/g
• Edibles: THC in milligrams per unit.
• Tinctures: mg/mL
Who can keep up with all this?
New Approach to Labeling
Sell the buzz, not dead weight
New Approaches to Labeling
Standard Drink
• With alcohol, we inherently know that we can drink more
ounces of beer than vodka before we are drunk.
• Standard Drink = fixed amount of pure alcohol.
• The volume changes to even out the amount of alcohol
consumed.
New Approaches to Labeling
Standard Dank
• Package sizing not by weight but THC or CBD amount.
• Standard Dank = 5 mg THC or CBD.
• Same cannabinoid mass across all product categories
• Package in serving sizes of Standard Danks.
Standard Danks: 1 40 85 180
New Approach to Labeling v2
More Medical Marijuana, less Recreational Cannabis, please!
New Approaches to Labeling
International Units
• Nutraceuticals sold with International Units (IU) on the label.
• Pharmacology: IU = measure of the effect.
• 1000 IU of Vitamin D per day.
• Arbitrary, but round number = easy to remember.
• It is based on biological activity.
• Easy to compare different forms, i.e. tablet or tincture.
New Approaches to Labeling
Intoxication Units
• For THC, CBD set a normalized number of 100 IU for a single
dose of effect.
• Edible: 5 mg of THC = 100 IU.
• Pre-rolls / Vape: One puff = 100 IU.
• CBD Tincture: 300mg of CBD = 100 IU.
Intoxication Units: 100 3,000 40,000 1000
New Approaches to Labeling
Intoxication Units
• But, that is difficult!
• So, do the work!
New Approaches to Labeling
Intoxication Units
• But, that is difficult!
• So, do the work!
Does Size matter for Performance?
A Study of how Particle Size
influences Joint Smoking
-10
10
30
50
70
90
110
Puff count cannabinoid/puff (mg*10) cannabinoid/joint (mg) % recovery
THC 1-mm THC 3-mm THC 5-mm CBD 1-mm CBD 3-mm CBD 5-mm
New Approaches to Labeling
Intoxication Units
• But, that is difficult!
• So, do the work!
A Randomized, Triple-Blind, Comparator-
Controlled Parallel Study Investigating the
Pharmacokinetics of Cannabidiol and
Tetrahydrocannabinol in a Novel Delivery
System, Solutech, in Association with
Cannabis Use History
Parting Thoughts
• %THC sells the first package, return customers look for flavor.
• %THC is a niche quality that no outsider understands.
• New customers might be put off by it.
• "The real quantitative quality marker in cannabis is terpene
concentration.” (Emerald Cup / SC Labs co-founder Alec Dixon)
Parting Thoughts
• Educate customers about flavor and effect, not just %THC.
• Don’t sell “weight + %THC”.
• Sell a fixed amount of THC.
• Sell convenience not math problems!
• Standard Dank: mass of cannabinoids before consumption.
• Intoxication Units: resulting effects after consumption.
Expertise
CSO: Dr. Markus Roggen
Dr. Roggen has been actively involved in the cannabis industry for over 5 years in executive positions
executive positions overseeing production, R&D and process optimization for multiple producers. Dr.
multiple producers. Dr. Roggen is also a trusted advisor and mentor for multiple startups, startup
startups, startup accelerators and organizations.
DELIC LabsTeam
Our team covers a wide range of expertise,
including analytical chemistry, process chemistry,
engineering physics, data science and statistics.
ScientificAdvisor: Prof.GlennSammis
Prof. Sammis is a Full Professor in the Chemistry Department at the University of British Columbia. He
has built an internationally recognized research group working on the development of novel synthetic
methods for the preparation of natural products and pharmaceuticals.
References
• https://thecannabisscientist.com/testing-processing/totally-
miscalculated-the-total-thc-problem
• https://www.cannabisbusinesstimes.com/article/why-current-thc-
labeling-confusing-holding-industry-back-dr-markus-roggen/
• https://www.liebertpub.com/doi/full/10.1089/can.2021.0176#utm
_source=FastTrack&utm_medium=email&utm_campaign=can
• https://www.cannabissciencetech.com/view/does-size-matter-
for-performance-a-study-of-how-particle-size-influences-joint-
smoking
Birds, Bees and Buds:  How to Talk About Cannabis and How to Label it Correctly

More Related Content

Similar to Birds, Bees and Buds: How to Talk About Cannabis and How to Label it Correctly

Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
Markus Roggen
 
Cannabinoid and Harm Reduction among cannabis users
Cannabinoid and Harm Reduction among cannabis users Cannabinoid and Harm Reduction among cannabis users
Cannabinoid and Harm Reduction among cannabis users
Sébastien Béguerie
 
How Can You Tell How Much THC and CBD is in Your Marijuana?
How Can You Tell How Much THC and CBD is in Your Marijuana?How Can You Tell How Much THC and CBD is in Your Marijuana?
How Can You Tell How Much THC and CBD is in Your Marijuana?
Evergreen Buzz
 
How Do You Know the Level of THC or CBD in Your Cannabis?
How Do You Know the Level of THC or CBD in Your Cannabis?How Do You Know the Level of THC or CBD in Your Cannabis?
How Do You Know the Level of THC or CBD in Your Cannabis?
Cannabis News
 
Hemp Processing Overview. Cultivate 2021
Hemp Processing Overview. Cultivate 2021Hemp Processing Overview. Cultivate 2021
Hemp Processing Overview. Cultivate 2021
Markus Roggen
 
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
Markus Roggen
 
2024 Numerator Consumer Study of Cannabis Usage
2024 Numerator Consumer Study of Cannabis Usage2024 Numerator Consumer Study of Cannabis Usage
2024 Numerator Consumer Study of Cannabis Usage
Neil Kimberley
 
Crystallizing the science of CBD purification
Crystallizing the science of  CBD purificationCrystallizing the science of  CBD purification
Crystallizing the science of CBD purification
Markus Roggen
 
Total Legal: A “Joint” Journey into the Chemistry of Cannabinoids
Total Legal: A “Joint” Journey into the Chemistry of CannabinoidsTotal Legal: A “Joint” Journey into the Chemistry of Cannabinoids
Total Legal: A “Joint” Journey into the Chemistry of Cannabinoids
Markus Roggen
 
Artificial Intelligence for Craft Cannabis Products
Artificial Intelligence for Craft Cannabis ProductsArtificial Intelligence for Craft Cannabis Products
Artificial Intelligence for Craft Cannabis Products
Markus Roggen
 
Cannabis Testing The Current Landscape
Cannabis Testing The Current LandscapeCannabis Testing The Current Landscape
Cannabis Testing The Current Landscape
Mike Bernhardt
 
Healthy Hemp Solutions CBD Presentation
Healthy Hemp Solutions CBD PresentationHealthy Hemp Solutions CBD Presentation
Healthy Hemp Solutions CBD Presentation
HealthyHempcom
 
ElSohley Award Lecture 2020
ElSohley Award Lecture 2020ElSohley Award Lecture 2020
ElSohley Award Lecture 2020
Markus Roggen
 
Cannabis Extraction:  A scientist’s approach to the industry
Cannabis Extraction:  A scientist’s approach to the industryCannabis Extraction:  A scientist’s approach to the industry
Cannabis Extraction:  A scientist’s approach to the industry
Markus Roggen
 
Don't Hold Your Breath! Cannabis Labs Virtual 2021
Don't Hold Your Breath! Cannabis Labs Virtual 2021Don't Hold Your Breath! Cannabis Labs Virtual 2021
Don't Hold Your Breath! Cannabis Labs Virtual 2021
Markus Roggen
 
LabRoots 2019: Molecular Manipulation
LabRoots 2019: Molecular ManipulationLabRoots 2019: Molecular Manipulation
LabRoots 2019: Molecular Manipulation
Markus Roggen
 
mythbusters-dispelling-drug-testing-myths (1).pdf
mythbusters-dispelling-drug-testing-myths (1).pdfmythbusters-dispelling-drug-testing-myths (1).pdf
mythbusters-dispelling-drug-testing-myths (1).pdf
ssuserfba5da
 
Crescent Pure
Crescent PureCrescent Pure
Crescent Pure
Vaishnavi Lakkaraju
 
How to make hemp CBD oil - Hemprove
How to make hemp CBD oil - HemproveHow to make hemp CBD oil - Hemprove
How to make hemp CBD oil - Hemprove
Hemprove
 
Why There is More THC in Your Cannabis Chocolates Than You Think
Why There is More THC in Your Cannabis Chocolates Than You ThinkWhy There is More THC in Your Cannabis Chocolates Than You Think
Why There is More THC in Your Cannabis Chocolates Than You Think
Evergreen Buzz
 

Similar to Birds, Bees and Buds: How to Talk About Cannabis and How to Label it Correctly (20)

Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
Cannabis Chemistry Industrial Applications of Chemistry & Innovation and Entr...
 
Cannabinoid and Harm Reduction among cannabis users
Cannabinoid and Harm Reduction among cannabis users Cannabinoid and Harm Reduction among cannabis users
Cannabinoid and Harm Reduction among cannabis users
 
How Can You Tell How Much THC and CBD is in Your Marijuana?
How Can You Tell How Much THC and CBD is in Your Marijuana?How Can You Tell How Much THC and CBD is in Your Marijuana?
How Can You Tell How Much THC and CBD is in Your Marijuana?
 
How Do You Know the Level of THC or CBD in Your Cannabis?
How Do You Know the Level of THC or CBD in Your Cannabis?How Do You Know the Level of THC or CBD in Your Cannabis?
How Do You Know the Level of THC or CBD in Your Cannabis?
 
Hemp Processing Overview. Cultivate 2021
Hemp Processing Overview. Cultivate 2021Hemp Processing Overview. Cultivate 2021
Hemp Processing Overview. Cultivate 2021
 
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
Don’t hold your breath: Smoke and vaping studies on cannabis products to qua...
 
2024 Numerator Consumer Study of Cannabis Usage
2024 Numerator Consumer Study of Cannabis Usage2024 Numerator Consumer Study of Cannabis Usage
2024 Numerator Consumer Study of Cannabis Usage
 
Crystallizing the science of CBD purification
Crystallizing the science of  CBD purificationCrystallizing the science of  CBD purification
Crystallizing the science of CBD purification
 
Total Legal: A “Joint” Journey into the Chemistry of Cannabinoids
Total Legal: A “Joint” Journey into the Chemistry of CannabinoidsTotal Legal: A “Joint” Journey into the Chemistry of Cannabinoids
Total Legal: A “Joint” Journey into the Chemistry of Cannabinoids
 
Artificial Intelligence for Craft Cannabis Products
Artificial Intelligence for Craft Cannabis ProductsArtificial Intelligence for Craft Cannabis Products
Artificial Intelligence for Craft Cannabis Products
 
Cannabis Testing The Current Landscape
Cannabis Testing The Current LandscapeCannabis Testing The Current Landscape
Cannabis Testing The Current Landscape
 
Healthy Hemp Solutions CBD Presentation
Healthy Hemp Solutions CBD PresentationHealthy Hemp Solutions CBD Presentation
Healthy Hemp Solutions CBD Presentation
 
ElSohley Award Lecture 2020
ElSohley Award Lecture 2020ElSohley Award Lecture 2020
ElSohley Award Lecture 2020
 
Cannabis Extraction:  A scientist’s approach to the industry
Cannabis Extraction:  A scientist’s approach to the industryCannabis Extraction:  A scientist’s approach to the industry
Cannabis Extraction:  A scientist’s approach to the industry
 
Don't Hold Your Breath! Cannabis Labs Virtual 2021
Don't Hold Your Breath! Cannabis Labs Virtual 2021Don't Hold Your Breath! Cannabis Labs Virtual 2021
Don't Hold Your Breath! Cannabis Labs Virtual 2021
 
LabRoots 2019: Molecular Manipulation
LabRoots 2019: Molecular ManipulationLabRoots 2019: Molecular Manipulation
LabRoots 2019: Molecular Manipulation
 
mythbusters-dispelling-drug-testing-myths (1).pdf
mythbusters-dispelling-drug-testing-myths (1).pdfmythbusters-dispelling-drug-testing-myths (1).pdf
mythbusters-dispelling-drug-testing-myths (1).pdf
 
Crescent Pure
Crescent PureCrescent Pure
Crescent Pure
 
How to make hemp CBD oil - Hemprove
How to make hemp CBD oil - HemproveHow to make hemp CBD oil - Hemprove
How to make hemp CBD oil - Hemprove
 
Why There is More THC in Your Cannabis Chocolates Than You Think
Why There is More THC in Your Cannabis Chocolates Than You ThinkWhy There is More THC in Your Cannabis Chocolates Than You Think
Why There is More THC in Your Cannabis Chocolates Than You Think
 

More from Markus Roggen

Have a Good Trip? How to Analyze Psychedelics
Have a Good Trip? How to Analyze PsychedelicsHave a Good Trip? How to Analyze Psychedelics
Have a Good Trip? How to Analyze Psychedelics
Markus Roggen
 
From Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
From Leaf to Lab: Uncovering the Molecular Mysteries of CannabisFrom Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
From Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
Markus Roggen
 
Your Secret Sauce to Succeeding as a Cannabis Business: A Data-Driven Approach
Your Secret Sauce to Succeeding as a  Cannabis Business:  A Data-Driven ApproachYour Secret Sauce to Succeeding as a  Cannabis Business:  A Data-Driven Approach
Your Secret Sauce to Succeeding as a Cannabis Business: A Data-Driven Approach
Markus Roggen
 
How Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
How Long Is Your Trip? Analysing the Micros and Heroics of PsychedelicsHow Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
How Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
Markus Roggen
 
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in CannabisSimulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
Markus Roggen
 
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-ChemieVon ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
Markus Roggen
 
Structure Activity Relationship between the Emerging Psychedelic Industry and...
Structure Activity Relationship between the Emerging Psychedelic Industry and...Structure Activity Relationship between the Emerging Psychedelic Industry and...
Structure Activity Relationship between the Emerging Psychedelic Industry and...
Markus Roggen
 
ACS Fall 2022: Purple Rain
ACS Fall 2022: Purple RainACS Fall 2022: Purple Rain
ACS Fall 2022: Purple Rain
Markus Roggen
 
Out of the Shadows: Identifying Impurities in Cannabis Products
Out of the Shadows: Identifying Impurities in Cannabis ProductsOut of the Shadows: Identifying Impurities in Cannabis Products
Out of the Shadows: Identifying Impurities in Cannabis Products
Markus Roggen
 
Deep Purple: Discolouration in CBD products
Deep Purple: Discolouration in CBD productsDeep Purple: Discolouration in CBD products
Deep Purple: Discolouration in CBD products
Markus Roggen
 
Slow is Smooth & Smooth is Fast!
Slow is Smooth & Smooth is Fast!Slow is Smooth & Smooth is Fast!
Slow is Smooth & Smooth is Fast!
Markus Roggen
 
Cannabis/Hemp Decarboxylation Monitoring by IR
Cannabis/Hemp Decarboxylation Monitoring by IRCannabis/Hemp Decarboxylation Monitoring by IR
Cannabis/Hemp Decarboxylation Monitoring by IR
Markus Roggen
 
Psilocybin Analytical Methods. MJBiz Daily Webinar
Psilocybin Analytical Methods. MJBiz Daily WebinarPsilocybin Analytical Methods. MJBiz Daily Webinar
Psilocybin Analytical Methods. MJBiz Daily Webinar
Markus Roggen
 
Data Analytics for Process Optimization
Data Analytics for Process OptimizationData Analytics for Process Optimization
Data Analytics for Process Optimization
Markus Roggen
 
Data-Analytics for Cannabis Extraction
Data-Analytics for Cannabis ExtractionData-Analytics for Cannabis Extraction
Data-Analytics for Cannabis Extraction
Markus Roggen
 
What is in your vape?! CannMed 2019 Presentation
What is in your vape?! CannMed 2019 PresentationWhat is in your vape?! CannMed 2019 Presentation
What is in your vape?! CannMed 2019 Presentation
Markus Roggen
 
Optimization of the Decarboxylation Reaction in Cannabis Extract
Optimization of the Decarboxylation Reaction in Cannabis ExtractOptimization of the Decarboxylation Reaction in Cannabis Extract
Optimization of the Decarboxylation Reaction in Cannabis Extract
Markus Roggen
 

More from Markus Roggen (17)

Have a Good Trip? How to Analyze Psychedelics
Have a Good Trip? How to Analyze PsychedelicsHave a Good Trip? How to Analyze Psychedelics
Have a Good Trip? How to Analyze Psychedelics
 
From Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
From Leaf to Lab: Uncovering the Molecular Mysteries of CannabisFrom Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
From Leaf to Lab: Uncovering the Molecular Mysteries of Cannabis
 
Your Secret Sauce to Succeeding as a Cannabis Business: A Data-Driven Approach
Your Secret Sauce to Succeeding as a  Cannabis Business:  A Data-Driven ApproachYour Secret Sauce to Succeeding as a  Cannabis Business:  A Data-Driven Approach
Your Secret Sauce to Succeeding as a Cannabis Business: A Data-Driven Approach
 
How Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
How Long Is Your Trip? Analysing the Micros and Heroics of PsychedelicsHow Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
How Long Is Your Trip? Analysing the Micros and Heroics of Psychedelics
 
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in CannabisSimulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
Simulations of Test Reduction Using Pooled Heavy Metals Analysis in Cannabis
 
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-ChemieVon ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
Von ⍺-Pinene bis O-acetyl-THC: Eine breite Übersicht der Cannabis-Chemie
 
Structure Activity Relationship between the Emerging Psychedelic Industry and...
Structure Activity Relationship between the Emerging Psychedelic Industry and...Structure Activity Relationship between the Emerging Psychedelic Industry and...
Structure Activity Relationship between the Emerging Psychedelic Industry and...
 
ACS Fall 2022: Purple Rain
ACS Fall 2022: Purple RainACS Fall 2022: Purple Rain
ACS Fall 2022: Purple Rain
 
Out of the Shadows: Identifying Impurities in Cannabis Products
Out of the Shadows: Identifying Impurities in Cannabis ProductsOut of the Shadows: Identifying Impurities in Cannabis Products
Out of the Shadows: Identifying Impurities in Cannabis Products
 
Deep Purple: Discolouration in CBD products
Deep Purple: Discolouration in CBD productsDeep Purple: Discolouration in CBD products
Deep Purple: Discolouration in CBD products
 
Slow is Smooth & Smooth is Fast!
Slow is Smooth & Smooth is Fast!Slow is Smooth & Smooth is Fast!
Slow is Smooth & Smooth is Fast!
 
Cannabis/Hemp Decarboxylation Monitoring by IR
Cannabis/Hemp Decarboxylation Monitoring by IRCannabis/Hemp Decarboxylation Monitoring by IR
Cannabis/Hemp Decarboxylation Monitoring by IR
 
Psilocybin Analytical Methods. MJBiz Daily Webinar
Psilocybin Analytical Methods. MJBiz Daily WebinarPsilocybin Analytical Methods. MJBiz Daily Webinar
Psilocybin Analytical Methods. MJBiz Daily Webinar
 
Data Analytics for Process Optimization
Data Analytics for Process OptimizationData Analytics for Process Optimization
Data Analytics for Process Optimization
 
Data-Analytics for Cannabis Extraction
Data-Analytics for Cannabis ExtractionData-Analytics for Cannabis Extraction
Data-Analytics for Cannabis Extraction
 
What is in your vape?! CannMed 2019 Presentation
What is in your vape?! CannMed 2019 PresentationWhat is in your vape?! CannMed 2019 Presentation
What is in your vape?! CannMed 2019 Presentation
 
Optimization of the Decarboxylation Reaction in Cannabis Extract
Optimization of the Decarboxylation Reaction in Cannabis ExtractOptimization of the Decarboxylation Reaction in Cannabis Extract
Optimization of the Decarboxylation Reaction in Cannabis Extract
 

Recently uploaded

Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Leonel Morgado
 
Randomised Optimisation Algorithms in DAPHNE
Randomised Optimisation Algorithms in DAPHNERandomised Optimisation Algorithms in DAPHNE
Randomised Optimisation Algorithms in DAPHNE
University of Maribor
 
Immersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths ForwardImmersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths Forward
Leonel Morgado
 
bordetella pertussis.................................ppt
bordetella pertussis.................................pptbordetella pertussis.................................ppt
bordetella pertussis.................................ppt
kejapriya1
 
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
yqqaatn0
 
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdfwaterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
LengamoLAppostilic
 
Basics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different formsBasics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different forms
MaheshaNanjegowda
 
SAR of Medicinal Chemistry 1st by dk.pdf
SAR of Medicinal Chemistry 1st by dk.pdfSAR of Medicinal Chemistry 1st by dk.pdf
SAR of Medicinal Chemistry 1st by dk.pdf
KrushnaDarade1
 
Bob Reedy - Nitrate in Texas Groundwater.pdf
Bob Reedy - Nitrate in Texas Groundwater.pdfBob Reedy - Nitrate in Texas Groundwater.pdf
Bob Reedy - Nitrate in Texas Groundwater.pdf
Texas Alliance of Groundwater Districts
 
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
vluwdy49
 
Medical Orthopedic PowerPoint Templates.pptx
Medical Orthopedic PowerPoint Templates.pptxMedical Orthopedic PowerPoint Templates.pptx
Medical Orthopedic PowerPoint Templates.pptx
terusbelajar5
 
Oedema_types_causes_pathophysiology.pptx
Oedema_types_causes_pathophysiology.pptxOedema_types_causes_pathophysiology.pptx
Oedema_types_causes_pathophysiology.pptx
muralinath2
 
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills MN
 
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC  APPERCEPTION  TEST(TAT) cognitive abilities, creativity, and critic...THEMATIC  APPERCEPTION  TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
Abdul Wali Khan University Mardan,kP,Pakistan
 
Equivariant neural networks and representation theory
Equivariant neural networks and representation theoryEquivariant neural networks and representation theory
Equivariant neural networks and representation theory
Daniel Tubbenhauer
 
8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf
by6843629
 
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
yqqaatn0
 
Micronuclei test.M.sc.zoology.fisheries.
Micronuclei test.M.sc.zoology.fisheries.Micronuclei test.M.sc.zoology.fisheries.
Micronuclei test.M.sc.zoology.fisheries.
Aditi Bajpai
 
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
University of Maribor
 
Shallowest Oil Discovery of Turkiye.pptx
Shallowest Oil Discovery of Turkiye.pptxShallowest Oil Discovery of Turkiye.pptx
Shallowest Oil Discovery of Turkiye.pptx
Gokturk Mehmet Dilci
 

Recently uploaded (20)

Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
 
Randomised Optimisation Algorithms in DAPHNE
Randomised Optimisation Algorithms in DAPHNERandomised Optimisation Algorithms in DAPHNE
Randomised Optimisation Algorithms in DAPHNE
 
Immersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths ForwardImmersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths Forward
 
bordetella pertussis.................................ppt
bordetella pertussis.................................pptbordetella pertussis.................................ppt
bordetella pertussis.................................ppt
 
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
如何办理(uvic毕业证书)维多利亚大学毕业证本科学位证书原版一模一样
 
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdfwaterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
 
Basics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different formsBasics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different forms
 
SAR of Medicinal Chemistry 1st by dk.pdf
SAR of Medicinal Chemistry 1st by dk.pdfSAR of Medicinal Chemistry 1st by dk.pdf
SAR of Medicinal Chemistry 1st by dk.pdf
 
Bob Reedy - Nitrate in Texas Groundwater.pdf
Bob Reedy - Nitrate in Texas Groundwater.pdfBob Reedy - Nitrate in Texas Groundwater.pdf
Bob Reedy - Nitrate in Texas Groundwater.pdf
 
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
 
Medical Orthopedic PowerPoint Templates.pptx
Medical Orthopedic PowerPoint Templates.pptxMedical Orthopedic PowerPoint Templates.pptx
Medical Orthopedic PowerPoint Templates.pptx
 
Oedema_types_causes_pathophysiology.pptx
Oedema_types_causes_pathophysiology.pptxOedema_types_causes_pathophysiology.pptx
Oedema_types_causes_pathophysiology.pptx
 
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...
 
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC  APPERCEPTION  TEST(TAT) cognitive abilities, creativity, and critic...THEMATIC  APPERCEPTION  TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
 
Equivariant neural networks and representation theory
Equivariant neural networks and representation theoryEquivariant neural networks and representation theory
Equivariant neural networks and representation theory
 
8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf
 
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
原版制作(carleton毕业证书)卡尔顿大学毕业证硕士文凭原版一模一样
 
Micronuclei test.M.sc.zoology.fisheries.
Micronuclei test.M.sc.zoology.fisheries.Micronuclei test.M.sc.zoology.fisheries.
Micronuclei test.M.sc.zoology.fisheries.
 
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
 
Shallowest Oil Discovery of Turkiye.pptx
Shallowest Oil Discovery of Turkiye.pptxShallowest Oil Discovery of Turkiye.pptx
Shallowest Oil Discovery of Turkiye.pptx
 

Birds, Bees and Buds: How to Talk About Cannabis and How to Label it Correctly

  • 1. Dr. Markus Roggen President / CSO Birds, Bees and Buds: How to Talk About Cannabis and How to Label it Correctly
  • 2. Math Class Sorry, no sex ed. today
  • 3. Exam Question 1 Mary Jane bought an eight of Lemon OG. This strain has 23.3% total THC. She then rolls one half-gram joint. If she takes three puffs, how much THC, in millimole, has she consumed?
  • 4. Exam Question 2 Bubba Kush has 20.2% THC and costs $4.20 per eight. Lemon OG has 23.3% THC and costs $7.10 per eight. Which one gives me the most bang for my buck?
  • 5. Exam Question 2 Bubba Kush has 20.2% THC and costs $4.20 per eight. Lemon OG has 23.3% THC and costs $7.10 per eight. Which one gives me the most bang for my buck? Cost per %point of THC: Bubba Kush: $0.21 Lemon OG: $0.30
  • 6. Outline • How do we buy cannabis today? • But total THC% is wrong and you lose money! • Current labeling is bad • New approaches to labeling
  • 7. Introduction DELIC Labs is a research venture that seeks to add fundamental scientific insight to the field of cannabis and mushroom production. We seek to support the cannabis and mushroom industries by establishing a centralized hub in Vancouver, BC, for collaborative research focused on: • Process Design • Process Optimization • Process Analytics • Formulation Research
  • 8. Collaborative Research DELIC Labs collaborates with academic, industry and private groups around the globe. Some highlights of those collaborations are: • University of British Columbia, Vancouver • Loyalist College, Belleville • Via Innovations by Dr. Monica Vialpando • Verdient Science by Dr. Linda Klumpers Fundamental Collaboration
  • 9. • Chemometrics and data analytics for process control and optimization • Kinetic studies to understand mechanisms • In-process analytics for process control • Computational studies to understand mechanisms • Process development, like crystallization Fundamental Cannabis and Mushroom Chemistry Research Topics
  • 10. How do We Buy Cannabis Today? Statistics on cannabis sales. Yes, more math!
  • 11. The Economics of Labeling • Consumers look at the %THC number and chose the highest. • Which other industry does that?
  • 12. The Economics of Labeling • Consumers look at the %THC number and chose the highest. • Which other industry does that? • Pharma? No!
  • 13. The Economics of Labeling • Which is the best wine?
  • 14. The Economics of Labeling • Which is the best wine?
  • 15. The Total THC% Problem • This is a pure THCA crystal: 100% THCA • Use following formula to calculate total THC% • 𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877 + ∆9𝑇𝐻𝐶 %𝑤𝑡. = total THC% • Therefore this pure THCA crystal has 87.7% total THC!?!
  • 16. The Total THC% Problem • A pure THCA crystal must have 100% total THC • Old Formula • 𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877 + ∆9𝑇𝐻𝐶 %𝑤𝑡. = 𝑡𝑜𝑡𝑎𝑙 %𝑇𝐻𝐶 • We have to add term for weight loss of sample • 𝑇𝐻𝐶𝐴 %𝑤𝑡. × 0.877+∆9𝑇𝐻𝐶 %𝑤𝑡. (𝑃𝑟𝑜𝑑𝑢𝑐𝑡 − 0.123∗𝑇𝐻𝐶𝐴) = 𝑡𝑜𝑡𝑎𝑙 𝑇𝐻𝐶%
  • 17. The Total THC% Problem • You are underreporting the amount of THC in your products. • You are losing $$$ per pound of flower. • Very rough estimate: 23.28 20.15 24.12 20.72 0 5 10 15 20 25 30 Lemon OG Bubba Kush Total THC (%) Figure 1: Cannabis Change in Total THC total THC% using new formula total THC% using current formula
  • 18. The Total THC% Problem • You are underreporting the amount of THC in your products. • You are losing $$$ per pound of flower. • Very rough estimate: •>$400 million missed for USA sales 2022 23.28 20.15 24.12 20.72 0 5 10 15 20 25 30 Lemon OG Bubba Kush Total THC (%) Figure 1: Cannabis Change in Total THC total THC% using new formula total THC% using current formula
  • 19. The Total THC% Problem • You are underreporting the amount of THC in your products. • You are losing $$$ per pound of flower. • And your hemp is hot! 0.29 0.24 0.30 0.25 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 Autopilot Hemp Belle W37 Total THC (%) Figure 2: Hemp Change in Total THC total THC% using new formula total THC% using current formula
  • 20. Labeling Mess Customer needs an advanced degree in mathematics • Flower: weight percentage, i.e. THC%
  • 21. Labeling Mess Customer needs an advanced degree in mathematics • Flower: weight percentage, i.e. THC% • Vape cartridges: THC% or mg/g
  • 22. Labeling Mess Customer needs an advanced degree in mathematics • Flower: weight percentage, i.e. THC% • Vape cartridges: THC% or mg/g • Edibles: THC in milligrams per unit.
  • 23. Labeling Mess Customer needs an advanced degree in mathematics • Flower: weight percentage, i.e. THC% • Vape cartridges: THC% or mg/g • Edibles: THC in milligrams per unit. • Tinctures: mg/mL Who can keep up with all this?
  • 24. New Approach to Labeling Sell the buzz, not dead weight
  • 25. New Approaches to Labeling Standard Drink • With alcohol, we inherently know that we can drink more ounces of beer than vodka before we are drunk. • Standard Drink = fixed amount of pure alcohol. • The volume changes to even out the amount of alcohol consumed.
  • 26. New Approaches to Labeling Standard Dank • Package sizing not by weight but THC or CBD amount. • Standard Dank = 5 mg THC or CBD. • Same cannabinoid mass across all product categories • Package in serving sizes of Standard Danks. Standard Danks: 1 40 85 180
  • 27. New Approach to Labeling v2 More Medical Marijuana, less Recreational Cannabis, please!
  • 28. New Approaches to Labeling International Units • Nutraceuticals sold with International Units (IU) on the label. • Pharmacology: IU = measure of the effect. • 1000 IU of Vitamin D per day. • Arbitrary, but round number = easy to remember. • It is based on biological activity. • Easy to compare different forms, i.e. tablet or tincture.
  • 29. New Approaches to Labeling Intoxication Units • For THC, CBD set a normalized number of 100 IU for a single dose of effect. • Edible: 5 mg of THC = 100 IU. • Pre-rolls / Vape: One puff = 100 IU. • CBD Tincture: 300mg of CBD = 100 IU. Intoxication Units: 100 3,000 40,000 1000
  • 30. New Approaches to Labeling Intoxication Units • But, that is difficult! • So, do the work!
  • 31. New Approaches to Labeling Intoxication Units • But, that is difficult! • So, do the work! Does Size matter for Performance? A Study of how Particle Size influences Joint Smoking -10 10 30 50 70 90 110 Puff count cannabinoid/puff (mg*10) cannabinoid/joint (mg) % recovery THC 1-mm THC 3-mm THC 5-mm CBD 1-mm CBD 3-mm CBD 5-mm
  • 32. New Approaches to Labeling Intoxication Units • But, that is difficult! • So, do the work! A Randomized, Triple-Blind, Comparator- Controlled Parallel Study Investigating the Pharmacokinetics of Cannabidiol and Tetrahydrocannabinol in a Novel Delivery System, Solutech, in Association with Cannabis Use History
  • 33. Parting Thoughts • %THC sells the first package, return customers look for flavor. • %THC is a niche quality that no outsider understands. • New customers might be put off by it. • "The real quantitative quality marker in cannabis is terpene concentration.” (Emerald Cup / SC Labs co-founder Alec Dixon)
  • 34. Parting Thoughts • Educate customers about flavor and effect, not just %THC. • Don’t sell “weight + %THC”. • Sell a fixed amount of THC. • Sell convenience not math problems! • Standard Dank: mass of cannabinoids before consumption. • Intoxication Units: resulting effects after consumption.
  • 35. Expertise CSO: Dr. Markus Roggen Dr. Roggen has been actively involved in the cannabis industry for over 5 years in executive positions executive positions overseeing production, R&D and process optimization for multiple producers. Dr. multiple producers. Dr. Roggen is also a trusted advisor and mentor for multiple startups, startup startups, startup accelerators and organizations. DELIC LabsTeam Our team covers a wide range of expertise, including analytical chemistry, process chemistry, engineering physics, data science and statistics. ScientificAdvisor: Prof.GlennSammis Prof. Sammis is a Full Professor in the Chemistry Department at the University of British Columbia. He has built an internationally recognized research group working on the development of novel synthetic methods for the preparation of natural products and pharmaceuticals.
  • 36. References • https://thecannabisscientist.com/testing-processing/totally- miscalculated-the-total-thc-problem • https://www.cannabisbusinesstimes.com/article/why-current-thc- labeling-confusing-holding-industry-back-dr-markus-roggen/ • https://www.liebertpub.com/doi/full/10.1089/can.2021.0176#utm _source=FastTrack&utm_medium=email&utm_campaign=can • https://www.cannabissciencetech.com/view/does-size-matter- for-performance-a-study-of-how-particle-size-influences-joint- smoking

Editor's Notes

  1. How we buy cannabis today Why this math is wrong The economics of current labeling (including all types of labels, terpenes vs. THC, Wine/Vodka) New Approaches to Labeling Standard Dank Joint paper Intoxication Units Volker’s paper Outro