Learn more about the Brazilian project that won silver medal in the 2014 iGEM synthetic biology in Boston / USA. A partnership between C.E.S.A.R and LIKA-UFPE.

2. A private institute that innovates in products, services and
companies with Information and Communication
Technologies (ICTs). Since its foundation in1996, the
center helps companies throughout the innovation life
cycle - from the study of contexts, design and prototyping
ideas, to developing solutions in various sectors.

3. Our mission is to perform self sustainable
transfer of knowledge in Information
Technologies between society and academia
society academia

4. design
studies &
research
prototyping
& evaluation development commercialization
C.E.S.A.R COMPANIES
setup

5. Services
Finanças
Telecom
Government
Electronic Industry
Energy
3º Sector

7. Solutions
INNOVATIVE
COMPLEX
Problems

8. Population aging combined with
increased awareness about
health have generated a greater
need for regular medical care,
which has significantly raised the
costs of the healthcare industry
in the world.

9. The treatment of
diseases is usually
performed in a
reactive way, so when
the disease is
diagnosed it is often
in an advanced stage
of development.
PATIENT DOCTOR LABORATORY
RESULTSDOCTORTREATMENT

10. Molecular diagnosis currently makes it
easy to detect primary diseases with high
specificity and sensitivity. However,
techniques are expensive, requiring much
time and skilled and trained personnel.
Ionn Torrent: state-of-the-art DNA
sequencer. It performs human genome
sequencing to estimate the risk of cancer
or other genetic diseases.
Biosensors come up as a portable
alternative, cheaper and simpler to handle
while maintaining the same sensitivity and
specificity of molecular diagnosis.
PCR Machine: performs real-
time analysis of patient
samples (cancer, viral and
bacterial diseases, etc..)

12. We believe that the use of biosensors for early detection and
diagnosis of diseases can increase the chances of patient
survival and reduce the costs of medical care compared to
reactive treatments in very advanced stages of diseases.

13. But there are still limitations of use
which prevent the unrestricted
application of biosensors by the
healthcare industry. To spread the
use of this technology, it is
necessary to develop more efficient,
reliable and user friendly systems.

15. Laboratory of Immunopathology Keizo Asami (LIKA), founded in
1986, has several research areas. Among them, there are the
diagnosis and the proposition of new therapeutic procedures.
LIKA is engaged in developing strategies to increase resolution
for diagnosis of genetic diseases, infectious agents, acquired
and autoimmune diseases.
[http://www.ufpe.br/lika/ ]

17. Bringing together LIKA's scientific experience with C.E.S.A.R.'s
technological skills, to develop biosensors for the detection of
breast cancer with the help of robotics.
The idea is to build a system which is able to process and prepare
small blood samples in an automated fashion. This system will be
coupled with biosensors that are capable of detecting breast
cancer in its early stages.
The goal is to shorten the analysis of samples from patients that
currently take 4-6 hours to less than 30 minutes.

18. http://2014.igem.org/Giant_Jamboree
The first milestone of this
partnership was the presentation
of this project at the iGEM
competition, at the event Giant
Jamboree on Nov/14 in Boston.
The event gathered more than
3000 participants during 5 days
of lectures and project
presentations. The LIKA-CESAR-
BRASIL team won a silver medal
at the competition.

19. The iGEM Competition 2014 is a
competition created by MIT for the
advancement of synthetic biology
through a worldwide competition
where teams develop their studies in
the construction of biological
systems to be operated in living cells.
http://igem.org/

22. ● Bring together a multidisciplinary team of researchers
● Create a network of complementary institutions
● Launch the LIKA.CESAR lab
● Explore the potential of biosensors in fields (agribusiness)

23. http://youtu.be/2V-yEJHLosk