BACKGROUND: Penetrating carotid artery injuries (PCAI) in civil time are infrequent, yet they present significant diagnostic and therapeutic challenges and can be associated with significant morbidity and mortality. Proper resuscitation and urgent exploration is necessary for actively bleeding patients.
OBJECTIVE: The aim of this paper is to present our humble experience in management of such injuries with literature review.
PATIENTS AND METHODS: Herein, we present 5 cases of penetrating carotid artery injuries managed in Sulaimania and Basrah from January 1996 to 30th of November 2009.
RESULTS: All patients were young males. Three injuries were located in zone III and 2 in zone II. Four patients presented hours to days after the injury while the fifth presented after few months. Angiography was done in 2 patients with a false aneurysm of internal carotid artery (ICA). All 3 patients with ICA injuries were managed by ligation due to profuse bleeding and poor access. The 2 patients with common carotid artery (CCA) injuries in zone II had an end to end repair. All 5 patients have survived without significant neurological deficits.
CONCLUSIONS: Penetrating carotid artery injuries in zone II usually do not require preoperative angiography unlike those in zone I and III. Repair is always desired. It is a straightforward operation for zone II injuries but really challenging for zone III due to poor access. Certain zone III injuries may be just observed or treated by endovascular stenting when facilities permit. Ligation of ICA carries a high risk of stroke; however, young people with well developed circle of Willis may tolerate it well.
Key Words: carotid artery, penetrating injury, zone I, II and III, neurological deficit.
Publication Date: 2013
Publication Name: The Iraqi Postgraduate Medical Journal
BACKGROUND: Penetrating carotid artery injuries (PCAI) in civil time are infrequent, yet they present significant diagnostic and therapeutic challenges and can be associated with significant morbidity and mortality. Proper resuscitation and urgent exploration is necessary for actively bleeding patients.
OBJECTIVE: The aim of this paper is to present our humble experience in management of such injuries with literature review.
PATIENTS AND METHODS: Herein, we present 5 cases of penetrating carotid artery injuries managed in Sulaimania and Basrah from January 1996 to 30th of November 2009.
RESULTS: All patients were young males. Three injuries were located in zone III and 2 in zone II. Four patients presented hours to days after the injury while the fifth presented after few months. Angiography was done in 2 patients with a false aneurysm of internal carotid artery (ICA). All 3 patients with ICA injuries were managed by ligation due to profuse bleeding and poor access. The 2 patients with common carotid artery (CCA) injuries in zone II had an end to end repair. All 5 patients have survived without significant neurological deficits.
CONCLUSIONS: Penetrating carotid artery injuries in zone II usually do not require preoperative angiography unlike those in zone I and III. Repair is always desired. It is a straightforward operation for zone II injuries but really challenging for zone III due to poor access. Certain zone III injuries may be just observed or treated by endovascular stenting when facilities permit. Ligation of ICA carries a high risk of stroke; however, young people with well developed circle of Willis may tolerate it well.
Key Words: carotid artery, penetrating injury, zone I, II and III, neurological deficit.
Publication Date: 2013
Publication Name: The Iraqi Postgraduate Medical Journal
case study of patient "H" ALL input is greatly wanted and appreciated. Would like to know if our study groups "patient" diagnosis and prognosis and order of events coincide.
Abnormal position of descending colon with right-sided sigmoid colon and its ...Apollo Hospitals
Variations in the disposition of colon are developmental in origin. Interruption of typical locations may lead to a variety of acute and chronic pathological conditions. Here we report an unusual case of abnormal position of descending colon with right-sided sigmoid colon observed in a 70-year old male cadaver during the routine dissections for undergraduate medical students. In the present case, the descending colon crossed the vertebral column at L4 level to reach the right pelvic brim to continue as right sided sigmoid colon. Awareness of this finding is of crucial significance when performing procedures like percutaneous gastrotomy and radiologically guided entrostomy as it can lead to fatal sepsis in patients who undergo minimally invasive procedures.
Laparoscopic Cholecystectomy in Situs Inversus Totalis Patient: Our Experienc...CrimsonPublishersAICS
Laparoscopic Cholecystectomy in Situs Inversus
Totalis Patient: Our Experience by Gulzar Ahmad Bhat* and Deepak Ghulliani in Advancements in Case Studies
Introduction: Envenomation is a public health problem in developing countries. Neurovascular complications are not exceptional.
Observations: We report two cases of hemorrhagic stroke which complicate an envenomation treated late.
The fi rst patient was 27 years old woman, who had been admitted for right hemiparesis and aphasia two weeks after a viperidae bite.
She was then treated with polyvalent antivenom (FAV-Afrique®).
case study of patient "H" ALL input is greatly wanted and appreciated. Would like to know if our study groups "patient" diagnosis and prognosis and order of events coincide.
Abnormal position of descending colon with right-sided sigmoid colon and its ...Apollo Hospitals
Variations in the disposition of colon are developmental in origin. Interruption of typical locations may lead to a variety of acute and chronic pathological conditions. Here we report an unusual case of abnormal position of descending colon with right-sided sigmoid colon observed in a 70-year old male cadaver during the routine dissections for undergraduate medical students. In the present case, the descending colon crossed the vertebral column at L4 level to reach the right pelvic brim to continue as right sided sigmoid colon. Awareness of this finding is of crucial significance when performing procedures like percutaneous gastrotomy and radiologically guided entrostomy as it can lead to fatal sepsis in patients who undergo minimally invasive procedures.
Laparoscopic Cholecystectomy in Situs Inversus Totalis Patient: Our Experienc...CrimsonPublishersAICS
Laparoscopic Cholecystectomy in Situs Inversus
Totalis Patient: Our Experience by Gulzar Ahmad Bhat* and Deepak Ghulliani in Advancements in Case Studies
Introduction: Envenomation is a public health problem in developing countries. Neurovascular complications are not exceptional.
Observations: We report two cases of hemorrhagic stroke which complicate an envenomation treated late.
The fi rst patient was 27 years old woman, who had been admitted for right hemiparesis and aphasia two weeks after a viperidae bite.
She was then treated with polyvalent antivenom (FAV-Afrique®).
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
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Bilateral Peripheral Arterial Disease.pdf
1. الرحيم الرحمن هللا بسم
Bilateral Peripheral Arterial
Disease
Prof. Abdulsalam Y Taha
College of Medicine
University of Sulaimani
2022 1
2. The Case
A 60-years old man presented with rest
pain in both lower limbs mainly on
right side of few months duration. He
was an ex-smoker. Abdominal
aortography and bilateral femoral
angiography revealed total occlusion
of right common iliac artery at its
origin with plenty of collaterals. There
was a faintly opacified profunda
femoris artery. 2
3. The Case…
The right SFA was occluded down
to popliteal artery which was
faintly filled by collaterals. The
distal run off vessels in right leg
were poor. On left side, there was
a lengthy occlusion of SFA with
dense collaterals. The popliteal
artery was visible and reformed
by collaterals. 3
10. The Case…
The surgical options offered to the patient
were left femoro-popliteal bypass. But on
the right side, the surgical options were
limited due to lengthy occlusion and poor
distal run off. We thought of exploration of
right femoral artery first and possibly
localized thromboendarterectomy. If this
succeeded, then a graft between abdominal
aorta and right femoral artery might be
possible. Later, one may perform a saphenos
graft between the femoral graft and
popliteal artery. Right lumbar
sympathectomy could also be an option.
10
11. Comment
The angiographic criteria for a bypass
arterial surgery are patent inflow
vessels, segmental occlusion and patent
distal run off vessels.
Accordingly left femoropopliteal bypass
could be an option for the left lower
limb arterial disease in this patient.
However, the surgical plan was more
complicated on the right side as the
aforementioned criteria were not met.
11