The document discusses configuration tips for backing up virtual machines using vSphere and Veeam. It recommends keeping software up to date, avoiding simple deployment models, and using the direct SAN backup method. Specific tips covered include using Veeam to create offsite backups with features like tape support, backup copy jobs, WAN acceleration, and replication. Recommendations are provided for backup job types like reversed incremental and synthetic full backups. Finally, tips are given for virtual machines hosting Microsoft applications.