The document describes the Axiom Genome-Wide AFR 1 Array, which provides high coverage of genetic variants associated with disease in African and African American populations. It was designed to maximize coverage of common and rare variants down to a minor allele frequency of 1% in specific gene regions and disease-associated areas. The array contains over 893,000 SNPs selected from genome-wide association studies and databases of disease-associated variants. It enables genome-wide association studies, replication, and fine mapping with one experiment.