This study investigated the presence of residues of the antimicrobials enrofloxacin and ciprofloxacin in broiler chicken tissues from 10 brands sold for human consumption in Curitiba, Brazil. Samples of breast muscle tissue from each brand were tested using liquid chromatography coupled with mass spectrometry. The analysis detected no residues of enrofloxacin or ciprofloxacin above the allowed limits of 20-100 micrograms per kilogram. The results indicate that regulations regarding antimicrobial residue levels in poultry meat for human consumption are being followed by the companies tested in this region of Brazil.