Appendicitis is caused by an obstruction in the appendix, usually by stool or a foreign object, which leads to bacterial infection. The classic symptoms are pain that begins in the lower right abdomen and progresses over hours. A physical exam may reveal tenderness at McBurney's point. Complications can arise if the appendix ruptures, leading to peritonitis or abscess formation. Treatment is an appendectomy, which can be performed via different incision types like a gridiron or Lanz incision.