The document discusses various modern medical imaging modalities used for anatomical, physiological, and combined imaging. It covers modalities such as CT, MRI, ultrasound, nuclear medicine studies including PET, and emerging techniques like molecular imaging. Specific clinical applications are also mentioned, including myocardial perfusion imaging and the advantages and disadvantages of techniques like echocardiography, SPECT, PET, and CT angiography for assessing cardiac function and perfusion.

2. Contemporay
Medical
IMAGING
• Dr. V. SIVA SUBRAMANIYAN
• Dept. of Nuclear Medicine
• Sri Sathya Sai Institute of
Higher Medical Sciences,
• Prashanthigram, PUTTAPARTHY

3. MODALITIES
ANATOMICAL PHYSILOGICAL COMBINED

4. ANATOMICAL
• PLANAR • CROSS
SECTIONAL
• PLAIN X-RAYS • ULTRASOUND
• INSUFLATION • C.T.SCAN
STUDIES
• TOMOGRAMS • M.R.I

5. PHYSIOLOGICAL
• CONTRAST X-RAYS
• Ba.SWALLOW, Ba.MEALS,
Ba.enema
• I.V.U, R.G.P,M.C.U,A.U,
• ANGIOGRAMS, VENOGRAM

6. PHYSIOLOGICAL
ii
USG;Growth profile,Bio-physical
profile,Post void residue
Doppler Studies: Continuous /
Pulsed / Power Doppler
Contrast enhanced Sonography

7. PHYSIOLOGICAL
iii
• NUCLEAR MEDICINE STUDIES
• PLANAR
• SPECT
• P.E.T

8. FUSIONIMAGING
• SOFTWARE FUSION
• CO-REGISTRATION
• SPECT – CT
• PET-CT
• PET- MRI

9. SPECIALITY
CARDIAC
GENIT0–URINARY
G ASTRO–INTESTINAL
HEPATOBILIARY

10. SPECIALITY
MUSCULOSKELETAL
NEURO
ONCOLOGICAL
PAEDIATRICS

11. SPECIALITY
INTERVENTIONAL
WOMENS IMAGING
MOLECULAR IMAGING
VIRTUAL IMAGING

16. FUSION
IMAGING
• P.E.T PRINCIPLE
• P.E.T- C.T APPLICATIONS
• ONCOLOGICAL PESPECTIVE

48. MOLECULAR
IMAGING
WHAT?
WHY?
HOW?
WHEN?

49. W H A T I S ..
• Molecular Imaging defined as
IN-VIVO characterisation and
imaging of
• BIOLOGICAL PROCESSES at the
Cellular and Molecular
• with TARGETTED IMAING
TECHNIQUES.

50. HOW IS IT DIFFE
RENT
• CONVENTIONAL I M A G I N G -
EFFECT OF A PATHOLOGICAL
PROCESS IS DEPICTED
• MOLECULAR IMAGING –
DEPICTS OR DELINEATE S THE
PATHOLOICAL PROCESS
CAUSING THE DISEASE

51. B A S I C T O O L ..
•MOLECULAR PROBES
•H IGH AFFINITY–2TYP
ES
• L.M.W – RECEPTOR LIGANDS
• ENZYME SUBSTRATES
• H.M.W- MONOCLONAL Ab
• RECOMBINENT PROTEINS

54. CRITICALISSUES
• CELL INTERNALISATI
ON
• A DE Q U A T E C O N C E N T R
ATION
•RETENTION FOR LONG
ER

55. METHODS OF IMAGING
NUCLEAR IMAGING
MAGNETIC RESONANCE
OPTICAL IMAGING

56. NUCLEAR STUDI
ES
• Na I SYMPORTER TRAPPING – I
131
• THYROID / LACTATING BREAST/
GASTRIC MUCOSA
• FDG PET

57. M. R . I
• MONOCRYSTALLINE IRON
OXIDE NANO-PARTICLES
• SECOND REPORTER SYSTEM
• ENZYMATIC HYDROLYSIS

59. OPTICAL
IMAGING
• NEAR INFRA RED
FLUROSCENCE IMAGING
• BIO-LUMINESCENT PROTEINS

66. MYOCARDIAL PERFUSION
IMAGING
WHAT TO CHOOSE
Dr. V. SivaSubramaniyan
Dept . Of Nuclear Medicine
SSSIHMS,PSN

67. MODALITIES
• D.S.E- Dobutamine Stress Echo
• M.C.E- Microbubble Contrast Echo
• Gated SPECT Studies
• CARDIAC P.E.T
• MDCT- Coronary CTA
• CARDIAC M.R.I
• EBCT- Electron Beam C.T

68. DSE
• Adv. • Dis Adv.
• Cheaper • Operator deped.
• Non-ionising • Poor window
• Better Details • High end Mach.
• Specific • Variable observ.
• Parameters • Standardisation
• Numerous • Subjective

69. MCE
• Adv • DisAdva.
• Specific • Costly
• Early Detection • Availability
• Parameters • Affordability
• Quantifiable • Operator
Dependancy

70. GATED SPECT
• ONE STOP SHOP
• MYOCARDIAL VIABILTY
• EJECTION FRACTION
• REGIONAL WALL THICKENING
• STRATIFICATION
• HAEMODYNAMIC RESPONSE

78. PET
• Adv • Disadv.
• Specific • Costly
• Gold Standard • Flow & viability
• Stunning Vs separately
Hibernation • Operator
• Fusion Studies Depend.
• Parametric • Radiation
Burden

79. C.T.A
• MDCT
• 4 / 16 / 64 / 256 ------ INFINITY
• EBCT
• LINEAR ACCELARATOR BASED
• IDEAL FOR CARDIAC CYCLE

84. EMERGING
TRENDS
• SEGMENTATION
• 3D/4D RECONSTRUCTIONS
• VIRTUAL REALITY
APPLICATIONS