This document discusses the importance of proper sedation and hydration protocols for nuclear medicine studies, especially in pediatric patients. Anesthesia is needed to minimize movement artifacts during scans and ensure diagnostic image quality. Guidelines recommend establishing intravenous access and giving oral or intravenous sedatives. Hydration protocols specify giving infants and children normal saline infusions before and after radiotracer injection to promote renal diuresis and allow accurate measurement of glomerular filtration rate. Following standardized protocols leads to benefits like avoiding repeat scans and making conclusive diagnoses.