what are Immunoglobulins , types and their structure .

1. ANTIBODY STRUCTURE

2. ANTIBODY DEFINITION
•A blood protein produced in response to a
specific antigen.
Antibodies are known as immunoglobulins ,are
Yshaped protein that are produced by immune
system .

3. IMMUNOGLOBULIN
•Are glycoproteins found in the serum portion of
the blood
•Humoral branch of the immune response
•Are produced by plasma cells in response to an
immunogen
•Vital role in immune response

5. •Heavy and light chains
•Disulfide bonds
•Interchain
•Intra chain
•Domain(heavy chain(4-5 domains)
•Light chain(2 domains)

7. HINGE REGION
•Amino acid rich region
•Mainly rich in cysteine and proline
•Found between CH1and CH2 domains

8. •Fab region
•Composed of one constant and one variable
domain of each of the heavy and light chain
•Fc region
•Tail region of an antibody which interacts
cell surface receptors called Fc receptors.