At Creative Biolabs, the proprietary protocol and tailored biopanning strategy allow the increase of candidates with higher affinity and desired specificity (e.g. binders recognize conformational epitope rather than linear epitope). In general, by conducting four rounds library screening, our scientists can select scFv/Fab antibodies with the affinity of 10-7. Through constructing serial sub-libraries of the isolated scFv/Fab antibodies, we can increase the affinity from 10-8 to 10-9. Moreover, Creative Biolabs has successfully obtained a scFv antibody with an extremely high affinity of 10-12.

1. antibody screening cells
• Featured Screening Services at Creative Biolabs
• Magic™ Therapeutic Antibody Discovery Service
• Premade Antibody Library Screening
• Premade Single Domain Antibody Library Screening
• Premade Peptide Library Screening
• Internalization Antibody Screening
• Protease Substrate Screening
• Thermal Stable scFv/Fab Screening
• pH-sensitive Biomolecules Discovery Services
• Other Applications of Our Library Screening Service
• Antibody discovery
• Affinity maturation
• Humanization
• Identify enzyme inhibitor
• Map epitopes on antigens
• Discover/Validate new therapeutic targets
• Discover interaction between ligand and receptor
• In terms of years of experience in phage display realm, Creative Biolabs utilizes its advanced technology platforms and specialized expertise to serve our global clients with high-quality library screening services. Our scientists are confident in tailoring our customers the most
reliable and cost-effective protocol to facilitate their meaningful research.