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AXIOMX

CAPTURING WORLD’S PROBLEMS
ABOUT AXIOMX
• AxioMx is applying knowledge gained from the past 15
  years of human genome sequencing to produce highly
  specific recombinant antibodies against the human
  proteome. The existing antibody development
  paradigm is too slow and does not always result in
  consistent, renewable, and quality antibodies. Through
  proprietary advances in traditional phage display
  antibody library design, phage display screening and
  affinity maturation technologies, we rapidly generate
  antibodies at the required binding and specificity
  criteria. At AxioMx, we believe our platform will lead
  to the wide adoption of recombinant antibody use in
  research and diagnostic applications.
Introducing Custom Antibody Services

• AxioMx offers custom recombinant antibody discovery and
  development services ranging from peptide synthesis to large-scale
  antibody production.
• Our custom antibody design and development process begins by
  understanding the antigen and establishing our customer's
  specification requirements for each antibody. Together we
  determine the desired antibody specificity, affinity, structural
  modifications, labels or tags, based on the applications and sample
  types with which the antibody will be used. The result is an
  application-optimized antibody that works.
• The AxioMx Antibody Development Team is comprised of
  proteomic and genomic experts. Together, we work with you from
  design to delivery of your custom antibody. Our focus is the quality
  of your experience working with us and the quality of your custom
  antibody.
Technology Summary
• AxioMx has developed synthetic recombinant antibody
  libraries, commonly known as phage display libraries,
  with greater than ten billion unique clones. Diversity in
  our libraries is restricted to the most variable positions
  in the complementarity determining regions (CDRs) of
  natural antibody sequences. Our antibody frameworks
  have been optimized for protein expression, and our
  libraries efficiently generate binders to peptides as
  well as protein antigens.
• We utilize a "rapid liquid approach" in our
  automated phage display screening methodology to
  select for antibodies with both high affinity and high
  specificity.
A Complete Services Offering. From
      Peptides to Production.

• Our range of services include phage display
  library development and screening services,
  epitope mapping, affinity maturation,
  antibody structural modification, and antibody
  production.
CONTACT US
• AxioMx, Inc.
  688 East Main Street
  Branford, CT 06405
• Main: 203-208-1918
  Fax: 203-433-4068
• Directions:
• Take I-95 to exit 55 for US-1 / East Main Street
  toward North Branford
  Turn right onto US-1 / East Main Street
  Travel 1.7 miles on US-1 / East Main Street to 688
  E. Main Street

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AXIOMX

  • 2. ABOUT AXIOMX • AxioMx is applying knowledge gained from the past 15 years of human genome sequencing to produce highly specific recombinant antibodies against the human proteome. The existing antibody development paradigm is too slow and does not always result in consistent, renewable, and quality antibodies. Through proprietary advances in traditional phage display antibody library design, phage display screening and affinity maturation technologies, we rapidly generate antibodies at the required binding and specificity criteria. At AxioMx, we believe our platform will lead to the wide adoption of recombinant antibody use in research and diagnostic applications.
  • 3. Introducing Custom Antibody Services • AxioMx offers custom recombinant antibody discovery and development services ranging from peptide synthesis to large-scale antibody production. • Our custom antibody design and development process begins by understanding the antigen and establishing our customer's specification requirements for each antibody. Together we determine the desired antibody specificity, affinity, structural modifications, labels or tags, based on the applications and sample types with which the antibody will be used. The result is an application-optimized antibody that works. • The AxioMx Antibody Development Team is comprised of proteomic and genomic experts. Together, we work with you from design to delivery of your custom antibody. Our focus is the quality of your experience working with us and the quality of your custom antibody.
  • 4. Technology Summary • AxioMx has developed synthetic recombinant antibody libraries, commonly known as phage display libraries, with greater than ten billion unique clones. Diversity in our libraries is restricted to the most variable positions in the complementarity determining regions (CDRs) of natural antibody sequences. Our antibody frameworks have been optimized for protein expression, and our libraries efficiently generate binders to peptides as well as protein antigens. • We utilize a "rapid liquid approach" in our automated phage display screening methodology to select for antibodies with both high affinity and high specificity.
  • 5. A Complete Services Offering. From Peptides to Production. • Our range of services include phage display library development and screening services, epitope mapping, affinity maturation, antibody structural modification, and antibody production.
  • 6.
  • 7. CONTACT US • AxioMx, Inc. 688 East Main Street Branford, CT 06405 • Main: 203-208-1918 Fax: 203-433-4068 • Directions: • Take I-95 to exit 55 for US-1 / East Main Street toward North Branford Turn right onto US-1 / East Main Street Travel 1.7 miles on US-1 / East Main Street to 688 E. Main Street