This document discusses aneuploidy, which is an abnormal number of chromosomes. It defines aneuploidy and provides examples of monosomy and trisomy. Monosomy is having one fewer chromosome, like Turner Syndrome which is missing an X chromosome. Trisomy is having one extra chromosome, the most common being Down Syndrome which is trisomy 21. The document outlines objectives and provides details about different types of aneuploidy conditions.

1. BIOL22
PRINCIPLES OF GENETICS
Prepared by:
Romeo B. Pore Jr.
Instructor:
Mr. Peter Sultan

2. ANEUPLOIDY

3. Objectives
 Discuss what is Aneuploidy
 What are the examples of Aneuploidy
 The difference between Monosomy and Trisomy

4. Aneuploidy
 Is an abnormal number of chromosomes such as
having a single extra chromosome (47) or a
missing chromosomes (45).

5. Two examples of Aneuploidy
 MONOSOMY
 TRISOMY

6. Two examples of Aneuploidy
 MONOSOMY
A human with monosomy would only have 45
chromosomes instead of 46.

7. Human with monosomy
e.g. Turner Syndrome

8. Types of monosomy
 COMPLETE MONOSOMY
This type is due to the unsuccessful
separation of a pair of chromosomes during meiosis
called Nondisjunction.
 PARTIAL MONOSOMY
Where only some of the chromosomes
missing

9. Two examples of Aneuploidy
 TRISOMY
Trisomy is a genetic condition that result in an extra copy of
a chromosomes. It has 47 chromosomes instead of 46.

11. Autosomal aneuploids
 Trisomy 13 or D-trisomy (Patau Syndrome)
 Trisomy 18 or E-trisomy (Edward Syndrome)
 Trisomy 21 or G-trisomy (Down Syndrome)